Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes

Proceedings of the Royal Society B: Biological Sciences

Volumn 280, Issue 1762, 2013, Pages

  Palmer, Duncan ^a,b   Frater, John ^b,c   Phillips, Rodney ^b,c   McLean, Angela R ^a,b   McVean, Gil ^a,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cytotoxic T lymphocyte; Escape; Genealogy; HIV; Peeling; Phylodynamics

Indexed keywords

CROSS SECTION; DATA SET; GENEALOGY; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE SYSTEM; NUMERICAL MODEL; PRESSURE EFFECT; STATISTICAL ANALYSIS; STOCHASTICITY;

EPITOPE; GAG PROTEIN; NEF PROTEIN; POL PROTEIN; VIRUS ANTIGEN;

BIOLOGICAL MODEL; COMPUTER SIMULATION; CYTOTOXIC T LYMPHOCYTE; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MOLECULAR EVOLUTION; MUTATION; PATHOLOGY; PHYLOGENY;

ANTIGENS, VIRAL; COMPUTER SIMULATION; EPITOPES, T-LYMPHOCYTE; EVOLUTION, MOLECULAR; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV INFECTIONS; HIV-1; HUMANS; MODELS, BIOLOGICAL; MUTATION; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PHYLOGENY; POL GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84891537769     PISSN: 09628452     EISSN: 14712954     Source Type: Journal    
DOI: 10.1098/rspb.2013.0696     Document Type: Article

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