Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 528-535

  Kongkeaw, Chuenjid ^a   Dilokthornsakul, Piyameth ^a,b   Thanarangsarit, Phurit ^a   Limpeanchob, Nanteetip ^a   Norman Scholfield, C ^a  

^a NARESUAN UNIVERSITY   (Thailand)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Bacopa monnieri; Brahmi; Cognition; Nootropic; Speed of attention

Indexed keywords

BACOPA MONNIERI EXTRACT;

ABDOMINAL CRAMP; ARTICLE; BACOPA MONNIERI; CINAHL; COCHRANE LIBRARY; COGNITION; DATA BASE; DEMENTIA; DIARRHEA; DRUG EFFICACY; EMBASE; FLU LIKE SYNDROME; GASTROINTESTINAL SYMPTOM; HUMAN; MEDLINE; MEMORY; META ANALYSIS; NAUSEA; NEUROPSYCHOLOGICAL TEST; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPONSE TIME; XEROSTOMIA;

BACOPA MONNIERI;

ADHD; ATTENTION DEFICIT HYPERACTIVITY DISORDER; AUDITORY VERBAL LEARNING TEST; AVLT; BACOPA MONNIERI; BRAHMI; COGNITION; MCI; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; MMSE; NOOTROPIC; SPEED OF ATTENTION;

BACOPA; COGNITION; HUMANS; PLANT EXTRACTS;

EID: 84891487115     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.11.008     Document Type: Article

References (45)

1. K. Abascal, and E. Yarnell Bacopa for the brain: a smart addition to western medicine Altern. Complement. Ther. 17 2011 21 25 (10.1089/rej.2013.1431)
2. S. Aguiar, and T. Borowski Neuropharmacological review of the nootropic herb Bacopa monnieri Rejuvenation Res. 16 2013 313 326 (10.1089/rej.2013.1431)
3. ® on memory improvement in elderly participants-a double blind placebo controlled study J. Pharmacol. Toxicol. 3 2008 425 434 10.3923/jpt.2008.425.434
4. M.L. Bell, M.G. Kenward, D.L. Fairclough, and N.J. Horton Differential dropout and bias in randomised controlled trials: when it matters and when it may not Br. Med. J. 346 2013 e8668 10.1136/bmj.e8668
5. J. Birks, and R.J. Harvey Donepezil for dementia due to Alzheimer's disease Cochrane Database Syst. Rev. 2006 (1) Art. no.: CD001190. 10.1002/14651858.CD001190.pub2
6. J. Bischkopf, A. Busse, and M.C. Angermeyer Mild cognitive impairment-a review of prevalence, incidence and outcome according to current approaches Acta Psychiatr. Scand. 206 2002 403 414 (10.1034/j.1600-0447.2002.01417.x)
7. C. Calabrese, W.L. Gregory, M. Leo, D. Kraemer, K. Bone, and B. Oken Effects of a standardized Bacopa monnieri extract on cognitive perfomance, anxiey, and depression in the elderly: a randomized double-blind, placebo-controlled trial J. Altern. Complement. Med. 14 2008 707 713 (10.1089/acm.2008.0018)
8. N. Campbell, A. Ayub, M.A. Boustani, C. Fox, M. Farlow, I. Maidment, and R. Howard Impact of cholinesterase inhibitors on behavioral and psychological symptoms of Alzheimer's disease: a meta-analysis Clin. Interv. Aging 3 2008 719 728
9. J.J. Deeks, J.P.T. Higgins, and D.G. Altman Analysis and undertaking meta-analysis J.P.T. Higgins, S. Green, Cochrane Handbook for Systematic Reviews of Interventions 2008 John Wiley & Sons Chichester
10. R. Dersimonian, and N. Laird Meta-analysis in clinical trials Control. Clini. Trials 7 1986 177 188
11. L.A. Downey, J. Kean, F. Nemeh, A. Lau, A. Poll, R. Gregory, M. Murray, J. Rourke, B. Patak, M.P. Pase, A. Zangara, J. Lomas, A. Scholey, and C. Stough An acute, double-blind, placebo-controlled crossover study of 320 mg and 640 mg doses of a special extract of Bacopa monnieri (CDRI 08) on sustained cognitive performance Phytother. Res. 27 2012 1407 1413 (10.1002/ptr.4864)
12. J.C. Dumville, D.J. Torgerson, and C.E. Hewitt Reporting attrition in randomised controlled trials Br. Med. J. 332 2006 969 971
13. M.S. Forman, J.Q. Trojanowski, and V.M. Lee Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs Nat. Med. 10 2004 1055 1063 (10.1038/nm1113)
14. S. Gauthier, B. Reisberg, M. Zaudig, R.C. Petersen, K. Ritchie, K. Broich, S. Belleville, H. Brodaty, D. Bennett, H. Chertkow, J.L. Cummings, M. de Leon, H. Feldman, M. Ganguli, H. Hampel, P. Scheltens, M.C. Tierney, P. Whitehouse, and B. Winblad Mild cognitive impairment Lancet 367 2006 1262 1270 (10.1016/S0140-6736(06)68542-5)
15. S. Goswami, A. Saoji, N. Kumar, V. Thawani, M. Tiwari, and M. Thawani Effect of Bacopa monnieri on cognitive functions in Alzheimer's disease patients Int. J. Collaborative Res. Intern. Med. Public Health 3 2011 285 293
16. J.P.T. Higgins, and S.G. Thompson Quantifying heterogeneity in a meta-analysis Stat. Med. 11 2002 1539 1558 (10.1002/sim.1186)
17. A.R. Jadad, R.A. Moore, A. Moore, D. Carroll, C. Jenkinson, D.J.M. Reynolds, D.J. Gavanhan, and H.J. MeQuay Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled Clin. Trials 17 1996 1 12 (10.1016/0197-2456(95)00134-4)
18. N. Kamkaew, C. Norman Scholfield, K. Ingkaninan, N. Taepavarapruk, and K. Chootip Bacopa monnieri increases cerebral blood flow in rat independent of blood pressure Phytother. Res. 27 2013 135 138 (10.1002/ptr.4685)
19. D.O. Kennedy, A.B. Scholey, and K.A. Wesnes Modulation of cognition and mood following administration of single doses of Ginkgo biloba, ginseng, and a ginkgo/ginseng combination to healthy young adults Physiol. Behav. 75 2002 739 751
20. N. Limpeanchob, S. Jaipan, S. Rattanakaruna, W. Phrompittayarat, and K. Ingkaninan Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture J. Ethnopharmacol. 120 2008 112 117 10.1016/j.jep.2008.07.039
21. P.J. Lin, and P.J. Neumann The economics of mild cognitive impairment Alzheimers Dement. 9 2012 243 251 10.1016/j.jalz.2012.05.2117
22. J.J. Manly, M.X. Tang, N. Schupf, Y. Stern, J.P. Vonsattel, and R. Mayeux Frequency and course of mild cognitive impairment in a multiethnic community Ann. Neurol. 63 2008 494 506 (10.1002/ana.21326)
23. B.H. May, M. Lit, C.C. Xue, A.W. Yang, A.L. Zhang, M.D. Owens, R. Head, L. Cobiac, C.G. Li, H. Hugel, and D.F. Story Herbal medicine for dementia: a systematic review Phytother. Res. 23 2009 447 459
24. D. Moher, S. Hopewell, K.F. Schulz, V. Montori, P.C. Gøtzsche, P.J. Devereaux, D. Elbourne, M. Egger, and D.G. Altman CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials Br. Med. J. 340 2010 c869
25. D. Moher, A. Liberati, J. Tetzlaff, and D.G. Altman Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Ann. Intern. Med. 151 2009 264 269 c869
26. A. Morgan, and J. Stevens Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial J. Altern. Complement. Med. 16 2010 735 739 10.1089/acm.2009.0342
27. P.J. Nathan, J. Clarke, J. Lloyd, C.W. Hutchison, L. Downey, and C. Stough The acute effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy normal subjects Hum. Psychopharmacol. Clin. Exp. 16 2001 345 351 (10.1002/hup.544)
28. C. Neale, D. Camfield, J. Reay, C. Stough, and A. Scholey Cognitive effects of two nutraceuticals Ginseng and Bacopa benchmarked against modafinil: a review and comparison of effect sizes Br. J. Clin. Pharmacol. 75 2013 728 737 (10.1111/bcp.12002)
29. Negi, K.S., Singh, Y.D., Kushwaha, K.P., Rastogi, C.K., Rathi, A.K., Srivastava, J.S., 2000. Clinical evaluation of memory enhancing properties of memory plus in children with attention deficit hyperactivity disorder. Indian J. Psychiatry 42, 42-50
30. M.A. Parra, L.L. Ascencio, H.F. Urquina, F. Manes, and A.M. Ibanez P300 and neuropsychological assessment in mild cognitive impairment and Alzheimer dementia Front. Neurol. 3 2012 (10.3389/fneur.2012.00172), 10 pp
31. M.P. Pase, J. Kean, J. Sarris, C. Neale, A.B. Scholey, and C. Stough The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials J. Altern. Complement. Med. 18 2012 647 652 10.1089/acm.2011.0367
32. T. Peth-Nui, J. Wattanathorn, S. Muchimapura, T. Tong-Un, N. Piyavhatkul, P. Rangseekajee, K. Ingkaninan, and S. Vittaya-areekul Effects of 12-week Bacopa monnieri consumption on attention, cognitive processing, working memory, and functions of both cholinergic and monoaminergic systems in healthy elderly volunteers Evid.-Based Complement. Altern. Med. 2012 2012 (10.1155/2012/606424) 2012, 10 pp, Article ID 606424
33. S. Raghav, H. Singh, P.K. Dalai, J.S. Srivastava, and O.P. Asthana Randomized controlled trial of standardized Bacopa monniera extract in age-associated memory impairment Indian J. Psychiatry 48 2006 238 242 (10.4103/0019-5545.31555)
34. M. Rajani Bacopa monnieri: A Nootropic Drug 2008 Springer Heidelberg, Berlin
35. M. Rastogi, R.P. Ojha, B.P. Devi, A. Aggarwal, A. Agrawal, and G.P. Dubey Amelioration of age associated neuroinflammation on long term bacosides treatment Neurochem. Res. 37 2012 869 874 (10.1007/s11064-011-0681-1)
36. S. Roodenrys, D. Booth, S. Bulzomi, A. Phipps, C. Micallef, and J. Smoker Chronic effects of Brahmi (Bacopa monnieri) on human memory Neuropsychopharmacology 27 2002 279 281 (10.1016/S0893-133X(01)00419-5)
37. A. Russo, and F. Borrelli Bacopa monniera, a reputed nootropic plant: an overview Phytomedicine 12 2005 305 317
38. V. Sathyanarayanan, T. Thomas, S.J.L. Einöther, R. Dobriyal, M.K. Joshi, and S. Krishnamachari Brahmi for the better? New findings challenging cognition and anti-anxiety effects of Brahmi (Bacopa monniera) in healthy adults Psychopharmacology 227 2013 299 306 (10.1007/s00213-013-2978-z)
39. C. Stough, J. Lloyd, L.A. Downey, C.W. Hutchison, T. Rodgers, and P.J. Nathan The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects Psychopharmacology 156 2001 481 484 (10.1007/s002130100815)
40. C. Stough, L.A. Downey, J. Lloyd, B. Silber, S. Redman, C.W. Hutchison, K. Wesnes, and P.J. Nathan Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial Phytother. Res. 22 2008 1629 1634 (10.1002/ptr.2537)
41. S.G. Thompson Why sources of heterogeneity in meta-analysis should be investigated? Br. Med. J. 309 1994 1351 1355
42. A.C. Tricco, C. Soobiah, S. Berliner, J.M. Ho, C.H. Ng, H.M. Ashoor, M.H. Chen, B. Hemmelgarn, and S.E. Straus Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis Can. Med. Assoc. J. 185 2013 1393 1401
43. N. Uabundit, J. Wattanathorn, S. Mucimapura, and K. Ingkaninan Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model J. Ethnopharmacol. 127 2010 26 31 (10.1016/j.jep.2009.09.056)
44. A. Wimo, and B. Winblad Pharmacoeconomics of mild cognitive impairment Acta Neurol. Scand. 170 2003 94 99
45. World Health Organization G. Avanzini, J.M. Bertolote, H. de Boer, H. Breivik, T. Dua, N. Graham, A. Janca, Neurological Disorders: Public Health Challenges 2006 WHO Press Geneva