Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 660-666

  Guo, Chao ^a   Zhu, Yanrong ^a   Weng, Yan ^a   Wang, Shiquan ^a   Guan, Yue ^a   Wei, Guo ^a   Yin, Ying ^a   Xi, Miaomaio ^a   Wen, Aidong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apigenin 7 O glucuronide (Pubchem CID: 5319484); Breviscapine; HO 1; I R; Nrf2; Scutellarin 7 O glucuronide (Pubchem CID: 185617); Therapeutic time window

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; BREVISCAPINE; FERRIC ION; HEME OXYGENASE 1; NEURON SPECIFIC ENOLASE; TRANSCRIPTION FACTOR NRF2;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN TISSUE; BRAIN WATER; CONTROLLED STUDY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; UPREGULATION; WATER CONTENT; WESTERN BLOTTING;

ERIGERON BREVISCAPUS; RATTUS;

APIGENIN-7-O-GLUCURONIDE (PUBCHEM CID: 5319484); BREVISCAPINE; HO-1; I/R; NRF2; SCUTELLARIN-7-O-GLUCURONIDE (PUBCHEM CID: 185617); THERAPEUTIC TIME WINDOW;

ANIMALS; BRAIN ISCHEMIA; ERIGERON; FLAVONOIDS; MALE; MOLECULAR STRUCTURE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY;

EID: 84891486373     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.11.026     Document Type: Article

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