Short-term prognostic value of serum neuron specific enolase and S100B in acute stroke patients

Clinical Biochemistry

Volumn 45, Issue 16-17, 2012, Pages 1302-1307

  González García, Sergio ^a   González Quevedo, Alina ^a   Fernández Concepción, Otman ^a   Peña Sánchez, Marisol ^a   Menéndez Saínz, Caridad ^a   Hernández Díaz, Zenaida ^a   Arteche Prior, Marianela ^a   Pando Cabrera, Alejandro ^a   Fernández Novales, Carlos ^b  

^a INSTITUTO DE NEUROLOGÍA Y NEUROCIRUGÍA   (Cuba)

^b University Hospital Cdte   (Cuba)

Author keywords

Hemorrhagic stroke; Ischemic stroke; Neuron specific enolase; Outcome; S100B; Stroke

Indexed keywords

NEURON SPECIFIC ENOLASE; PROTEIN S100B;

ADULT; AGED; ANAMNESIS; ARTICLE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; COMORBIDITY; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; DISEASE SEVERITY; ENZYME BLOOD LEVEL; FEMALE; HIGH RISK PATIENT; HOSPITAL ADMISSION; HUMAN; IMMUNOASSAY; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; RATING SCALE; SYMPTOM;

ADULT; AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; DEPRESSION; FEMALE; HUMANS; INTRACRANIAL HEMORRHAGES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NERVE GROWTH FACTORS; PHOSPHOPYRUVATE HYDRATASE; PROGNOSIS; REGRESSION ANALYSIS; ROC CURVE; S100 PROTEINS; STATISTICS, NONPARAMETRIC;

EID: 84868300132     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2012.07.094     Document Type: Article

References (30)

1. Ohira T., Shahar E., Chambless L.E., Rosamond W.D., Mosley T.H., Folsom A.R. Risk factors for ischemic stroke subtypes. The Atherosclerosis Risk in Communities Study. Stroke 2006, 37:2493-2498.
2. Selakovic V., Raicevic R., Radenovic L. The increase of neuron-specific enolase in cerebrospinal fluid and plasma as a marker of neuronal damage in patients with acute brain infarction. J Clin Neurosci 2005, 12:542-547.
3. Dassan P., Keir G., Brown M.M. Criteria for a clinically informative serum biomarker in acute ischaemic stroke: a review of S100B. Cerebrovasc Dis 2009, 27:295-302.
4. Rundgrena M., Karlsson T., Nielsen N., Cronberg T., Johnsson P., Friberg H. Neuron specific enolase and S-100B as predictors of outcome after cardiac arrest and induced hypothermia. Resuscitation 2009, 80:784-789.
5. Whiteley W. Identifying blood biomarkers to improve the diagnosis of stroke. J R Coll Physicians Edinb 2011, 41:152-154.
6. Jickling G.C., Sharp F.R. Blood biomarkers of ischemic stroke. Neurotherapeutics 2011, 8:349-360.
7. González-García S., González-Quevedo A., Fernández-Concepción O., Peña-Sánchez M., Menéndez-Saínz C., Hernández-Díaz Z., et al. Serum neuron specific enolase and S100 calcium binding protein B biomarker levels do not improve diagnosis of acute stroke. J R Coll Physicians Edinb 2012, (3).
8. Whiteley W., Chong W.L., Sengupta A., Sandercock P. Blood markers for the prognosis of ischemic stroke: a systematic review. Stroke 2009, 40:e380-e389.
9. Konstantinou E.A., Venetsanou K., Mitsos A.P., Mamoura K.V., Theodosopoulou E.E., Fotis T., et al. Neuron specific enolase (NSE): a valuable prognostic factor of central nervous system dysfunction following cardiac surgery. Br J Anaesth Recovery Nurs 2008, 9:22-28.
10. Al-Rawi N.H., Atiyah K.M. Salivary neuron specific enolase: an indicator for neuronal damage in patients with ischemic stroke and stroke-prone patients. Clin Chem Lab Med 2009, 47:1519-1524.
11. González-Quevedo A., González García S., Fernández Concepción O., Santiesteban Freixas R., Quevedo Sotolongo L., Menéndez Saínz M.C., et al. Increased serum S-100B and neuron specific enolase-potential markers of early nervous system involvement in essential hypertension. Clin Biochem 2011, 44:154-159.
12. Buergo Zuaznábar M.A., Fernández Concepción O. Guías de Práctica Clínica. Enfermedad Cerebrovascular 2009, Editorial de Ciencias Médicas, La Habana, Cuba.
13. Brott T., Marler J.R., Olinger C.P., Adams H.P., Tomsick T., Barsan W.G., et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 1989, 20:864-870.
14. Bamford J., Sandercock P., Dennis M., Burn J., Warlow C. Classification and natural history of clinical subtypes of cerebral infarction. Lancet 1991, 337:1521-1526.
15. Adams H.P., Bendixen B.H., Kappelle L.J., Biller J., Love B.B., Gordon D.L., et al. Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial: TOAST Trial of Org 10172 in acute stroke treatment. Stroke 1993, 24:35-41.
16. Granger C.V., Dewis L.S., Peters N.C., Sherwood C.C., Barrett J.E. Stroke rehabilitation: analysis of repeated Barthel index measures. Arch Phys Med Rehabil 1979, 60(1):14-17.
17. Sheikh J.I., Yesavage J.A. Geriatric Depression Scale (GDS). Recent evidence and development of a shorter version. Clinical gerontology: a guide to assessment and intervention 1986, 165-173. The Haworth Press Inc., New York. T.L. Brink (Ed.).
18. Bloomfield S.M., McKinney J., Smith L., Brisman J. Reliability of S100B in predicting severity of central nervous system injury. Neurocrit Care 2007, 6:121-138.
19. Kim J.S., Yoon S.S., Kim Y.H., Ryu J.S. Serial measurement of interleukin-6, transforming growth factor-beta, and S-100 protein in patients with acute stroke. Stroke 1996, 27:1553-1557.
20. Brea D., Sobrino T., Blanco M., Cristobo I., Rodríguez-González R., Rodríguez-Yañez M., et al. Temporal profile and clinical significance of serum neuron-specific enolase and S100 in ischemic and hemorrhagic stroke. Clin Chem Lab Med 2009, 47(12):1513-1518.
21. Fassbender K., Schmidt R., Schreiner A., Fatar M., Mühlhauser F., Daffertshofer M., et al. Leakage of brain-originated proteins in peripheral blood: temporal profile and diagnostic value in early ischemic stroke. J Neurol Sci 1997, 148:101-105.
22. Cunningham R.T., Young I.S., Winder J., O'Kane M.J., McKinstry S., Johnston C.F., et al. Serum neurone-specific enolase (NSE) levels as an indicator of neuronal damage in patients with cerebral infarction. Eur J Clin Invest 1991, 21:497-500.
23. Missler U., Wiesmann M., Friedrich C., Kaps M. S-100 protein and neuron-specific enolase concentrations in blood as indicators of infarction volume and prognosis in acute ischemic stroke. Stroke 1997, 28:1956-1960.
24. Wunderlich M.T., Ebert A.D., Kratz T., Goertler M., Jost S., Herrmann M. Early neurobehavioral outcome after stroke is related to release of neurobiochemical markers of brain damage. Stroke 1999, 30:1190-1195.
25. Saenger A.K., Christenson R.H. Stroke biomarkers: progress and challenges for diagnosis, prognosis, differentiation, and treatment. Clin Chem 2010, 56(1):21-33.
26. Jauch E.C., Lindsell Ch., Broderick J., Fagan S., Tilley B., Levine S.R. Association of serial biochemical markers with acute ischemic stroke: The National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study. Stroke 2006, 37:2508-2513.
27. Pham N., Fazio V., Cucullo L., Teng Q., Biberthaler P., Bazarian J.J., et al. PLoS One Sep. 2010, 5(9). [pii: e12691].
28. Schroeter M.L., Abdul-Khaliq H., Sacher J., Steiner J., Blasig I.E., Mueller K. Mood disorders are glial disorders: evidence from in vivo studies. Cardiovasc Psychiatr Neurol 2010, [Article ID 780645]. 10.1155/2010/780645.
29. Falcone T., Fazio V., Lee C., Simon B., Franco K., Marchi N., et al. Serum S100B: a potential biomarker for suicidality in adolescents?. PLoS One 2010, 5(6):e11089. 10.1371/journal.pone.0011089.
30. Tulner D.M., Smith O.R., de Jonge P., van Melle J.P., Slomp J., Storm H., et al. Circulating cerebral S100B protein is associated with depressive symptoms following myocardial infarction. Neuropsychobiology 2009, 59(2):87-95.