Eupafolin, a skin whitening flavonoid isolated from Phyla nodiflora, downregulated melanogenesis: Role of MAPK and Akt pathways

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 386-393

  Ko, Horng Huey ^a   Chiang, Yao Chang ^b,c   Tsai, Ming Horng ^d   Liang, Chan Jung ^e   Hsu, Lee Fen ^e   Li, Shu Yu ^f   Wang, Moo Chin ^a   Yen, Feng Lin ^a   Lee, Chiang Wen ^e  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^e CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^f TAJEN UNIVERSITY   (Taiwan)

Author keywords

Eupafolin; Melanogenesis; Microphthalmia associated transcription factor; Tyrosinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEPIGMENTING AGENT; EUPAFOLIN; FLAVONOID; MELANIN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOPHENOL MONOOXYGENASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMELANOGENESIS ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; KERATINOCYTE; MEDICINAL PLANT; MELANOGENESIS; MELANOMA CELL; MOUSE; NONHUMAN; PHYLA NODIFLORA; PROTEIN EXPRESSION; REDUCTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

PHYLA NODIFLORA;

EUPAFOLIN; MELANOGENESIS; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; TYROSINASE;

ANIMALS; CELL LINE; DOWN-REGULATION; FLAVONES; HUMANS; KERATINOCYTES; MELANINS; MELANOMA; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR STRUCTURE; PIGMENTATION DISORDERS; PLANT COMPONENTS, AERIAL; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; VERBENACEAE;

EID: 84891483036     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.10.054     Document Type: Article

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