Licochalcones suppress degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells

International Immunopharmacology

Volumn 10, Issue 7, 2010, Pages 769-776

  Tanifuji, Shota ^a   Aizu Yokota, Eriko ^a   Funakoshi Tago, Megumi ^a   Sonoda, Yoshiko ^a   Inoue, Hideo ^b   Kasahara, Tadashi ^a  

^a KEIO UNIVERSITY   (Japan)

^b Minophagen Pharmaceutical Co Ltd   (Japan)

Author keywords

Ca2+ influx; Degranulation; ERK; Licochalcone D; Mast cell

Indexed keywords

ANTIINFLAMMATORY AGENT; AZELASTINE; BETA N ACETYLHEXOSAMINIDASE; CALCIUM ION; ECHINATIN; ISOLIQUIRITIGENIN; LICOCHALCONE; LICOCHALCONE A; LICOCHALCONE B; LICOCHALCONE C; LICOCHALCONE D; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLANT MEDICINAL PRODUCT; PROTEIN KINASE SYK; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; EXTRACELLULAR CALCIUM; HISTAMINE RELEASE; IC 50; LEUKEMIA CELL LINE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BASOPHILS; CALCIUM; CELL DEGRANULATION; CELL LINE, TUMOR; CHALCONES; CYTOPROTECTION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCYRRHIZA; INTRACELLULAR SPACE; PHOSPHORYLATION; PHYTOTHERAPY; PLANT ROOTS; RATS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

EID: 77953020809     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.04.007     Document Type: Article

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