Modulating protein-DNA interactions by post-translational modifications at disordered regions

Pacific Symposium on Biocomputing

Volumn , Issue , 2012, Pages 188-199

  Vuzman, Dana ^a   Hoffman, Yonit ^a   Levy, Yaakov ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; DNA; PHOSPHORYLATION;

DNA-BINDING PROTEIN; INTRINSICALLY DISORDERED REGIONS; PHOSPHORYLATION SITES; POSITIVELY CHARGED; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN-DNA INTERACTIONS; RANDOMLY DISTRIBUTED; SPECIFIC AND NONSPECIFIC INTERACTIONS;

PROTEINS;

DNA BINDING PROTEIN; ETS1 PROTEIN, HUMAN; PROTEIN; PROTEIN P53; TP53 PROTEIN, HUMAN; TRANSCRIPTION FACTOR ETS 1;

ACETYLATION; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOLOGY; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN PROCESSING;

ACETYLATION; AMINO ACID SEQUENCE; BINDING SITES; COMPUTATIONAL BIOLOGY; DNA-BINDING PROTEINS; HUMANS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; PROTO-ONCOGENE PROTEIN C-ETS-1; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84891425838     PISSN: 23356928     EISSN: 23356936     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (48)

1. H. Xie, S. Vucetic, L. M. Iakoucheva, C. J. Oldfield, A. K. Dunker, Z. Obradovic and V. N. Uversky, Journal of proteome research, 2007, 6, 1917-1932.
2. V. N. Uversky, C. J. Oldfield, U. Midic, H. Xie, B. Xue, S. Vucetic, L. M. Iakoucheva, Z. Obradovic and A. K. Dunker, BMC genomics, 2009, 10 Suppl 1, S7.
3. C. R. Landry, E. D. Levy and S. W. Michnick, Trends Genet, 2009, 25, 193-197.
4. L. M. Iakoucheva, P. Radivojac, C. J. Brown, T. R. O'Connor, J. G. Sikes, Z. Obradovic and A. K. Dunker, Nucleic acids research, 2004, 32, 1037-1049.
5. O. Givaty and Y. Levy, Journal of the molecular biology, 2009, 385, 1087-1097.
6. A. Marcovitz and Y. Levy, Proc Natl Acad Sci USA, In press
7. A. I. Dragan, Z. L. Li, E. N. Makeyeva, E. I. Milgotina, Y. Y. Liu, C. Crane-Robinson and P. L. Privalov, Biochemistry, 2006, 45, 141-151.
8. C. Crane-Robinson, A. I. Dragan and P. L. Privalov, Trends in Bioch Sci, 2006, 31, 547-552.
9. D. Vuzman, A. Azia and Y. Levy, J Mol Biol, 2010, 396, 674-684.
10. D. Vuzman and Y. Levy, Proc Natl Acad Sci USA, 2010, 107, 21004-21009.
11. A. Tóth-Petróczy, M. Fuxreiter and Y. Levy, J Amer Chem Soc, 2009, 131, 15084-15085
12. P. L. Privalov, A. I. Dragan, C. Crane-Robinson, K. J. Breslauer, D. P. Remeta and C. A. S. A. Minetti, J Mol Biol, 2007, 365, 1-9.
13. J. M. Gruschus, D. H. Tsao, L. H. Wang, M. Nirenberg and J. A. Ferretti, Biochemistry, 1997, 36, 5372-5380.
14. R. Joshi, J. M. Passner, R. Rohs, R. Jain, A. Sosinsky, M. A. Crickmore, V. Jacob, A. K. Aggarwal, B. Honig and R. S. Mann, Cell, 2007, 131, 530-543.
15. P. L. Privalov, A. I. Dragan, C. Crane-Robinson, K. J. Breslauer, D. P. Remeta and C. A. Minetti, J Mol Biol, 2007, 365, 1-9.
16. A. I. Dragan, Z. Li, E. N. Makeyeva, E. I. Milgotina, Y. Liu, C. Crane-Robinson and P. L. Privalov, Biochemistry, 2006, 45, 141-151.
17. J. Iwahara and G. M. Clore, J Am Chem Soc, 2006, 128, 404-405.
18. T. Hu and B. I. Shklovskii, Physical Review E, 2007, 76, 051909.
19. M. Doucleff and G. M. Clore, Proc Natl Acad Sci USA, 2008, 105, 13871-13876.
20. A. J. Bannister and E. A. Miska, Cell Mol Life Sci, 2000, 57, 1184-1192.
21. A. J. Whitmarsh and R. J. Davis, Cell Mol Life Sci, 2000, 57, 1172-1183.
22. A. M. Bode and Z. G. Dong, Nature Reviews Cancer, 2004, 4, 793-805.
23. E. Appella and C. W. Anderson, European Journal of Biochemistry, 2001, 268, 2764-2772.
24. X. Yang, Cell Death and Differentiation, 2003, 10, 400-403.
25. J. Y. Luo, M. Y. Li, Y. Tang, M. Laszkowska, R. G. Roeder and W. Gu, Proc Natl Acad Sci USA, 2004, 101, 2259-2264.
26. K. Sakaguchi, H. Sakamoto, D. Xie, J. W. Erickson, M. S. Lewis, C. W. Anderson and E. Appella, J Prot Chem 1997, 16, 553-556.
27. A. Eberharter and P. B. Becker, Embo Reports, 2002, 3, 224-229.
28. S. Y. Roth, J. M. Denu and C. D. Allis, Annual Review of Biochemistry, 2001, 70, 81-120.
29. Z. Y. Yang, C. Y. Zheng and J. J. Hayes, Journal of Biological Chemistry, 2007, 282, 7930-7938.
30. B. M. Turner, Bioessays, 2000, 22, 836-845.
31. Z. Dosztanyi, V. Csizmok, P. Tompa and I. Simon, Bioinformatics, 2005, 21, 3433-3434.
32. D. Vuzman, M. Polonsky and Y. Levy, Biophys J, 2010, 99, 1202-1211.
33. P. Tompa, Structure and function of intrinsically disordered proteins, Boca Raton, 2010.
34. A. K. Dunker, I. Silman, V. N. Uversky and J. L. Sussman, Curr Opin Struct Biol, 2008, 18, 756-764.
35. V. N. Uversky, C. J. Oldfield and A. K. Dunker, Annual Rev of Biophysics, 2008, 37, 215-246.
36. T. Hagai, A. Azia, A. Tóth-Petróczy and Y. Levy, J Mol Biol, 2011, 412, 319-324, (2011)
37. D. Vuzman and Y. Levy, Submitted, Mol BioSystems, In press.
38. M. Fuxreiter, I. Simon and S. Bondos, Trends in Bioch Sci, 36, 415-423, (2011)
39. C. Choudhary, C. Kumar, F. Gnad, M. L. Nielsen, M. Rehman, T. C. Walther, J. V. Olsen and M. Mann, Science, 2009, 325, 834-840.
40. A. R. Fersht, A. Tafvizi, F. Huang, L. A. Mirny and A. M. van Oijen, Proc Natl Acad Sci USA, 2011, 108, 563-568.
41. N. Khazanov and Y. Levy, J Mol Biol, 2011, 408, 335-355.
42. L. Jayaraman and C. Prives, Cellular and Molecular Life Sciences, 1999, 55, 76-87.
43. W. Gu and R. G. Roeder, Cell, 1997, 90, 595-606.
44. S. J. Nowak and V. G. Corces, Trends Genet, 2004, 20, 214-220.
45. M. A. Pufall, G. M. Lee, M. L. Nelson, H. S. Kang, A. Velyvis, L. E. Kay, L. P. McIntosh and B. J. Graves, Science, 2005, 309, 142-145.
46. A. H. Mao, S. L. Crick, A. Vitalis, C. L. Chicoine and R. V. Pappu, Proc Natl Acad Sci USA, 2010, 107, 8183-8188.
47. M. Borg, T. Mittag, T. Pawson, M. Tyers, J. D. Forman-Kay and H. S. Chan, Proc Natl Acad Sci USA, 2007, 104, 9650-9655.
48. D. Potoyan and G. Papoian, J Amer Chem Soc, 2011, 133, 7405-7415.