메뉴 건너뛰기




Volumn 52, Issue 1, 2014, Pages 21-32

Glucosepane: A poorly understood advanced glycation end product of growing importance for diabetes and its complications

Author keywords

carbonyl stress; glycemia; HbA1c; methyglyoxal; nephropathy; neuropathy; retinopathy

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ARGININE; CARBONYL DERIVATIVE; GLUCOSE; GLUCOSEPANE; HEMOGLOBIN A1C; LYSINE; UNCLASSIFIED DRUG; WATER;

EID: 84891394604     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2013-0174     Document Type: Review
Times cited : (56)

References (46)
  • 2
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The DCCT Research Group The Diabetes Control and Complications Trial Research Group
    • The DCCT Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 1993;329:977-86.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 3
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UKPDS33 UK Prospective Diabetes Study (UKPDS) Group
    • UKPDS33. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998;352:837-53.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 4
    • 0037986208 scopus 로고    scopus 로고
    • Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus
    • Nathan DM, Lachin J, Cleary P, Orchard T, Brillon DJ, Backlund JY, et al. Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus. N Engl J Med 2003;348: 2294-303.
    • (2003) N Engl J Med , vol.348 , pp. 2294-2303
    • Nathan, D.M.1    Lachin, J.2    Cleary, P.3    Orchard, T.4    Brillon, D.J.5    Backlund, J.Y.6
  • 5
    • 33845534203 scopus 로고    scopus 로고
    • The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study
    • Cleary PA, Orchard TJ, Genuth S, Wong ND, Detrano R, Backlund JY, et al. The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Diabetes 2006;55:3556-65.
    • (2006) Diabetes , vol.55 , pp. 3556-3565
    • Cleary, P.A.1    Orchard, T.J.2    Genuth, S.3    Wong, N.D.4    Detrano, R.5    Backlund, J.Y.6
  • 7
    • 65449151412 scopus 로고    scopus 로고
    • Therapies for hyperglycaemia-induced diabetic complications: From animal models to clinical trials
    • Calcutt NA, Cooper ME, Kern TS, Schmidt AM. Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials. Nature Rev Drug Disc 2009;8:417-29.
    • (2009) Nature Rev Drug Disc , vol.8 , pp. 417-429
    • Calcutt, N.A.1    Cooper, M.E.2    Kern, T.S.3    Schmidt, A.M.4
  • 9
    • 0242691177 scopus 로고    scopus 로고
    • Cross-linking of proteins by Maillard processes-characterization and detection of a lysinearginine cross-link derived from D-glucose
    • Lederer MO, Buhler HP. Cross-linking of proteins by Maillard processes-characterization and detection of a lysinearginine cross-link derived from D-glucose. Bioorg Med Chem 1999;7:1081-8.
    • (1999) Bioorg Med Chem , vol.7 , pp. 1081-1088
    • Lederer, M.O.1    Buhler, H.P.2
  • 10
    • 70349314616 scopus 로고    scopus 로고
    • Degradation of glucose: Reinvestigation of reactive alpha-dicarbonyl compounds
    • Gobert J, Glomb MA. Degradation of glucose: reinvestigation of reactive alpha-dicarbonyl compounds. J Agric Food Chem 2009;57:8591-7.
    • (2009) J Agric Food Chem , vol.57 , pp. 8591-8597
    • Gobert, J.1    Glomb, M.A.2
  • 11
    • 0037908888 scopus 로고    scopus 로고
    • Site-specific quantitative evaluation of the protein glycation product N(6)-(2,3-Dihydroxy-5,6-dioxohexyl)-l-lysinate by LC-(ESI)MS peptide mapping: Evidence for its key role in AGE formation
    • Biemel KM, Lederer MO. Site-specific quantitative evaluation of the protein glycation product N(6)-(2,3-Dihydroxy-5,6-dioxohexyl)-l-lysinate by LC-(ESI)MS peptide mapping: evidence for its key role in AGE formation. Bioconjug Chem 2003;14:619-28.
    • (2003) Bioconjug Chem , vol.14 , pp. 619-628
    • Biemel, K.M.1    Lederer, M.O.2
  • 12
    • 0026708910 scopus 로고
    • Crosslines A and B as candidates for the flurophores in age-and diabetesrelated cross-linked proteins, and their diacetates produced by Maillard reaction of alpha-N-acetyl-L-lysine with D-glucose
    • Nakamura K, Hasegawa T, Fukunaga Y, Ienaga K. Crosslines A and B as candidates for the flurophores in age-and diabetesrelated cross-linked proteins, and their diacetates produced by Maillard reaction of alpha-N-acetyl-L-lysine with D-glucose. J Chem Soc Chem Comm 1992:992-4.
    • (1992) J Chem Soc Chem Comm , pp. 992-994
    • Nakamura, K.1    Hasegawa, T.2    Fukunaga, Y.3    Ienaga, K.4
  • 13
    • 0034105927 scopus 로고    scopus 로고
    • Crossline levels in serum and erythrocyte membrane proteins from patients with diabetic nephropathy
    • Aoki S, Hasegawa G, Shigeta H, Obayashi H, Fujii M, Kimura F, et al. Crossline levels in serum and erythrocyte membrane proteins from patients with diabetic nephropathy. Diabetes Res Clin Pract 2000;48:119-25.
    • (2000) Diabetes Res Clin Pract , vol.48 , pp. 119-125
    • Aoki, S.1    Hasegawa, G.2    Shigeta, H.3    Obayashi, H.4    Fujii, M.5    Kimura, F.6
  • 14
    • 78751489575 scopus 로고    scopus 로고
    • Favored and disfavored pathways of protein crosslinking by glucose: Glucose lysine dimer (GLUCOLD) and crossline versus glucosepane
    • Nemet I, Strauch CM, Monnier VM. Favored and disfavored pathways of protein crosslinking by glucose: glucose lysine dimer (GLUCOLD) and crossline versus glucosepane. Amino Acids 2011;40:167-81.
    • (2011) Amino Acids , vol.40 , pp. 167-181
    • Nemet, I.1    Strauch, C.M.2    Monnier, V.M.3
  • 15
    • 84861227538 scopus 로고    scopus 로고
    • Theoretical studies on models of lysine-arginine cross-links derived from alpha-oxoaldehydes: A new mechanism for glucosepane formation
    • Nasiri R, Zahedi M, Jamet H, Moosavi-Movahedi AA. Theoretical studies on models of lysine-arginine cross-links derived from alpha-oxoaldehydes: A new mechanism for glucosepane formation. J Mol Model 2012;18:1645-59.
    • (2012) J Mol Model , vol.18 , pp. 1645-1659
    • Nasiri, R.1    Zahedi, M.2    Jamet, H.3    Moosavi-Movahedi, A.A.4
  • 16
    • 0034136370 scopus 로고    scopus 로고
    • Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo
    • Takeuchi M, Makita Z, Bucala R, Suzuki T, Koike T, Kameda Y. Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo. Mol Med 2000;6:114-25.
    • (2000) Mol Med , vol.6 , pp. 114-125
    • Takeuchi, M.1    Makita, Z.2    Bucala, R.3    Suzuki, T.4    Koike, T.5    Kameda, Y.6
  • 18
    • 16844380283 scopus 로고    scopus 로고
    • Glucosepane is a major protein cross-link of the senescent human extracellular matrix. Relationship with diabetes
    • Sell DR, Biemel KM, Reihl O, Lederer MO, Strauch CM, Monnier VM. Glucosepane is a major protein cross-link of the senescent human extracellular matrix. Relationship with diabetes. J Biol Chem 2005;280:12310-5.
    • (2005) J Biol Chem , vol.280 , pp. 12310-12315
    • Sell, D.R.1    Biemel, K.M.2    Reihl, O.3    Lederer, M.O.4    Strauch, C.M.5    Monnier, V.M.6
  • 19
    • 77955095090 scopus 로고    scopus 로고
    • Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysis
    • Fan X, Sell DR, Zhang J, Nemet I, Theves M, Lu J, et al. Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysis. Free Radic Biol Med 2010;49:847-56.
    • (2010) Free Radic Biol Med , vol.49 , pp. 847-856
    • Fan, X.1    Sell, D.R.2    Zhang, J.3    Nemet, I.4    Theves, M.5    Lu, J.6
  • 20
    • 0032997958 scopus 로고    scopus 로고
    • Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: Relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial
    • Monnier VM, Bautista O, Kenny D, Sell DR, Fogarty J, Dahms W, et al. Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial. Diabetes 1999;48:870-80.
    • (1999) Diabetes , vol.48 , pp. 870-880
    • Monnier, V.M.1    Bautista, O.2    Kenny, D.3    Sell, D.R.4    Fogarty, J.5    Dahms, W.6
  • 21
    • 84861074989 scopus 로고    scopus 로고
    • Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli)
    • Dammann P, Sell DR, Begall S, Strauch C, Monnier VM. Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli). J Gerontol A Biol Sci Med Sci 2012;67:573-83.
    • (2012) J Gerontol A Biol Sci Med Sci , vol.67 , pp. 573-583
    • Dammann, P.1    Sell, D.R.2    Begall, S.3    Strauch, C.4    Monnier, V.M.5
  • 22
    • 19944432813 scopus 로고    scopus 로고
    • Paradoxical effects of green tea (camellia sinensis) and antioxidant vitamins in diabetic rats: Improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking
    • Mustata GT, Rosca M, Biemel KM, Reihl O, Smith MA, Viswanathan A, et al. Paradoxical effects of green tea (camellia sinensis) and antioxidant vitamins in diabetic rats: improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking. Diabetes 2005;54:517-26.
    • (2005) Diabetes , vol.54 , pp. 517-526
    • Mustata, G.T.1    Rosca, M.2    Biemel, K.M.3    Reihl, O.4    Smith, M.A.5    Viswanathan, A.6
  • 23
    • 0037067723 scopus 로고    scopus 로고
    • Identification and quantification of major Maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound
    • Biemel KM, Friedl DA, Lederer MO. Identification and quantification of major Maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound. J Biol Chem 2002;277:24907-15.
    • (2002) J Biol Chem , vol.277 , pp. 24907-24915
    • Biemel, K.M.1    Friedl, D.A.2    Lederer, M.O.3
  • 24
    • 0034671714 scopus 로고    scopus 로고
    • Effect of collagen turnover on the accumulation of advanced glycation end products
    • Verzijl N, DeGroot J, Thorpe SR, Bank RA, Shaw JN, Lyons TJ, et al. Effect of collagen turnover on the accumulation of advanced glycation end products. J Biol Chem 2000;275:39027-31.
    • (2000) J Biol Chem , vol.275 , pp. 39027-39031
    • Verzijl, N.1    Degroot, J.2    Thorpe, S.R.3    Bank, R.A.4    Shaw, J.N.5    Lyons, T.J.6
  • 25
    • 0019503151 scopus 로고
    • Effects of age and diabetes mellitus on the solubility and nonenzymatic glucosylation of human skin collagen
    • Schnider SL, Kohn RR. Effects of age and diabetes mellitus on the solubility and nonenzymatic glucosylation of human skin collagen. J Clin Invest 1981;67:1630-5.
    • (1981) J Clin Invest , vol.67 , pp. 1630-1635
    • Schnider, S.L.1    Kohn, R.R.2
  • 26
    • 0019935512 scopus 로고
    • Effects of age and diabetes mellitus on the solubility of collagen from human skin, tracheal cartilage and dura mater
    • Schnider SL, Kohn RR. Effects of age and diabetes mellitus on the solubility of collagen from human skin, tracheal cartilage and dura mater. Exp Gerontol 1982;17:185-94.
    • (1982) Exp Gerontol , vol.17 , pp. 185-194
    • Schnider, S.L.1    Kohn, R.R.2
  • 27
    • 0018676475 scopus 로고
    • Native cross-links in collagen fibrils induce resistance to human synovial collagenase
    • Vater CA, Harris ED, Jr., Siegel RC. Native cross-links in collagen fibrils induce resistance to human synovial collagenase. Biochem J 1979;181:639-45.
    • (1979) Biochem J , vol.181 , pp. 639-645
    • Vater, C.A.1    Harris Jr., E.D.2    Siegel, R.C.3
  • 28
    • 34249930891 scopus 로고    scopus 로고
    • Isolation, purification and characterization of histidino-threosidine, a novel Maillard reaction protein crosslink from threose, lysine and histidine
    • Dai Z, Nemet I, Shen W, Monnier VM. Isolation, purification and characterization of histidino-threosidine, a novel Maillard reaction protein crosslink from threose, lysine and histidine. Arch Biochem Biophys 2007;463:78-88.
    • (2007) Arch Biochem Biophys , vol.463 , pp. 78-88
    • Dai, Z.1    Nemet, I.2    Shen, W.3    Monnier, V.M.4
  • 30
  • 31
    • 0022931516 scopus 로고
    • Identification of N epsiloncarboxymethyllysine as a degradation product of fructoselysine in glycated protein
    • Ahmed MU, Thorpe SR, Baynes JW. Identification of N epsiloncarboxymethyllysine as a degradation product of fructoselysine in glycated protein. J Biol Chem 1986;261:4889-94.
    • (1986) J Biol Chem , vol.261 , pp. 4889-4894
    • Ahmed, M.U.1    Thorpe, S.R.2    Baynes, J.W.3
  • 32
    • 79960008006 scopus 로고    scopus 로고
    • Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues
    • Chetyrkin S, Mathis M, Pedchenko V, Sanchez OA, McDonald WH, Hachey DL, et al. Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues. Biochemistry 2011;50:6102-12.
    • (2011) Biochemistry , vol.50 , pp. 6102-6112
    • Chetyrkin, S.1    Mathis, M.2    Pedchenko, V.3    Sanchez, O.A.4    McDonald, W.H.5    Hachey, D.L.6
  • 34
    • 80054796926 scopus 로고    scopus 로고
    • Vitamin C degradation products and pathways in the human lens
    • Nemet I, Monnier VM. Vitamin C degradation products and pathways in the human lens. J Biol Chem 2011;286:37128-36.
    • (2011) J Biol Chem , vol.286 , pp. 37128-37136
    • Nemet, I.1    Monnier, V.M.2
  • 35
    • 0022644227 scopus 로고
    • Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking
    • Brownlee M, Vlassara H, Kooney A, Ulrich P, Cerami A. Aminoguanidine prevents diabetes-induced arterial wall protein cross-linking. Science 1986;232:1629-32.
    • (1986) Science , vol.232 , pp. 1629-1632
    • Brownlee, M.1    Vlassara, H.2    Kooney, A.3    Ulrich, P.4    Cerami, A.5
  • 36
    • 0142058743 scopus 로고    scopus 로고
    • Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: A novel therapy for treatment of diabetic complications
    • Metz TO, Alderson NL, Thorpe SR, Baynes JW. Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: A novel therapy for treatment of diabetic complications. Arch Biochem Biophys 2003;419:41-9.
    • (2003) Arch Biochem Biophys , vol.419 , pp. 41-49
    • Metz, T.O.1    Alderson, N.L.2    Thorpe, S.R.3    Baynes, J.W.4
  • 37
    • 80053019857 scopus 로고    scopus 로고
    • Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice
    • Fan X, Liu X, Potts B, Strauch C, Nemet I, Monnier V. Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice. Mol Vis 2011;17:2221-7.
    • (2011) Mol Vis , vol.17 , pp. 2221-2227
    • Fan, X.1    Liu, X.2    Potts, B.3    Strauch, C.4    Nemet, I.5    Monnier, V.6
  • 38
    • 33747080843 scopus 로고    scopus 로고
    • Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification
    • Dobler D, Ahmed N, Song L, Eboigbodin KE, Thornalley PJ. Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification. Diabetes 2006;55:1961-9.
    • (2006) Diabetes , vol.55 , pp. 1961-1969
    • Dobler, D.1    Ahmed, N.2    Song, L.3    Eboigbodin, K.E.4    Thornalley, P.J.5
  • 39
    • 0242468729 scopus 로고    scopus 로고
    • Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry
    • Thornalley PJ, Battah S, Ahmed N, Karachalias N, Agalou S, Babaei-Jadidi R, et al. Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry. Biochem J 2003;375:581-92.
    • (2003) Biochem J , vol.375 , pp. 581-592
    • Thornalley, P.J.1    Battah, S.2    Ahmed, N.3    Karachalias, N.4    Agalou, S.5    Babaei-Jadidi, R.6
  • 40
    • 84875229685 scopus 로고    scopus 로고
    • The association between skin collagen glucosepane and past progression of microvascular and neuropathic complications in type 1 diabetes
    • Monnier VM, Sell DR, Strauch C, Sun W, Lachin JM, Cleary PA, et al. The association between skin collagen glucosepane and past progression of microvascular and neuropathic complications in type 1 diabetes. J Diabetes Complications 2013;27:141-9.
    • (2013) J Diabetes Complications , vol.27 , pp. 141-149
    • Monnier, V.M.1    Sell, D.R.2    Strauch, C.3    Sun, W.4    Lachin, J.M.5    Cleary, P.A.6
  • 41
    • 77956394914 scopus 로고    scopus 로고
    • DCCT and EDIC studies in type 1 diabetes: Lessons for diabetic neuropathy regarding metabolic memory and natural history
    • Pop-Busui R, Herman WH, Feldman EL, Low PA, Martin CL, Cleary PA, et al. DCCT and EDIC studies in type 1 diabetes: lessons for diabetic neuropathy regarding metabolic memory and natural history. Curr Diab Rep 2010;10:276-82.
    • (2010) Curr Diab Rep , vol.10 , pp. 276-282
    • Pop-Busui, R.1    Herman, W.H.2    Feldman, E.L.3    Low, P.A.4    Martin, C.L.5    Cleary, P.A.6
  • 42
    • 33644698951 scopus 로고    scopus 로고
    • Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes
    • Genuth S, Sun W, Cleary P, Sell DR, Dahms W, Malone J, et al. Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes. Diabetes 2005;54:3103-11.
    • (2005) Diabetes , vol.54 , pp. 3103-3111
    • Genuth, S.1    Sun, W.2    Cleary, P.3    Sell, D.R.4    Dahms, W.5    Malone, J.6
  • 43
    • 23744467295 scopus 로고    scopus 로고
    • Glycation products as markers and predictors of the progression of diabetic complications
    • Monnier VM, Sell DR, Genuth S. Glycation products as markers and predictors of the progression of diabetic complications. Ann N Y Acad Sci 2005;1043:567-81.
    • (2005) Ann N y Acad Sci , vol.1043 , pp. 567-581
    • Monnier, V.M.1    Sell, D.R.2    Genuth, S.3
  • 44
    • 79959656594 scopus 로고    scopus 로고
    • Advanced glycation end products, measured as skin autofluorescence and diabetes complications: A systematic review
    • Bos DC, de Ranitz-Greven WL, de Valk HW. Advanced glycation end products, measured as skin autofluorescence and diabetes complications: A systematic review. Diabetes Technol Ther 2011;13:773-9.
    • (2011) Diabetes Technol Ther , vol.13 , pp. 773-779
    • Bos, D.C.1    De Ranitz-Greven, W.L.2    De Valk, H.W.3
  • 45
    • 84858433338 scopus 로고    scopus 로고
    • Biomarkers in diabetes: Hemoglobin A1c, vascular and tissue markers
    • Lyons TJ, Basu A. Biomarkers in diabetes: hemoglobin A1c, vascular and tissue markers. Transl Res 2012;159:303-12.
    • (2012) Transl Res , vol.159 , pp. 303-312
    • Lyons, T.J.1    Basu, A.2
  • 46
    • 84862692196 scopus 로고    scopus 로고
    • Glycation and biomarkers of vascular complications of diabetes
    • Beisswenger PJ. Glycation and biomarkers of vascular complications of diabetes. Amino Acids 2012;42:1171-83.
    • (2012) Amino Acids , vol.42 , pp. 1171-1183
    • Beisswenger, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.