메뉴 건너뛰기




Volumn 33, Issue 11, 2013, Pages 4779-4784

Comprehensive survey of HRAS, KRAS, NRAS mutations in proliferative thyroid lesions from an ethnically diverse population

Author keywords

BRAF mutations; Follicular patterned thyroid lesions; HRAS; KRAS; KRAS codon 59 deletion; NRAS mutations

Indexed keywords

B RAF KINASE; K RAS PROTEIN; SELUMETINIB;

EID: 84891365202     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (40)

References (42)
  • 1
    • 7644237134 scopus 로고    scopus 로고
    • Mutant RAS-induced proliferation of human thyroid epithelial cells requires three effector pathways
    • Bounacer A, McGregor A, Skinner J, Bond J, Poghosyan Z and Wynford-Thomas D: Mutant RAS-induced proliferation of human thyroid epithelial cells requires three effector pathways. Oncogene 23: 7839-7845, 2004.
    • (2004) Oncogene , vol.23 , pp. 7839-7845
    • Bounacer, A.1    McGregor, A.2    Skinner, J.3    Bond, J.4    Poghosyan, Z.5    Wynford-Thomas, D.6
  • 2
    • 84863640576 scopus 로고    scopus 로고
    • RAS Mutations and oncogenesis: Not all RAS mutations are created equally
    • Miller MS and Miller LD: RAS Mutations and oncogenesis: Not all RAS mutations are created equally. Front Genet 2: 100, 2011.
    • (2011) Front Genet , vol.2 , pp. 100
    • Miller, M.S.1    Miller, L.D.2
  • 4
    • 79960038169 scopus 로고    scopus 로고
    • Functional specificity of RAS isoforms: So similar but so different
    • Castellano E and Santos E: Functional specificity of RAS isoforms: So similar but so different. Genes Cancer 2: 216-231, 2011.
    • (2011) Genes Cancer , vol.2 , pp. 216-231
    • Castellano, E.1    Santos, E.2
  • 5
    • 84861147473 scopus 로고    scopus 로고
    • A comprehensive survey of RAS mutations in cancer
    • Prior IA, Lewis PD and Mattos C: A comprehensive survey of RAS mutations in cancer. Cancer Res 72: 2457-2467, 2012.
    • (2012) Cancer Res , vol.72 , pp. 2457-2467
    • Prior, I.A.1    Lewis, P.D.2    Mattos, C.3
  • 6
    • 79960052850 scopus 로고    scopus 로고
    • RAS in cancer and developmental diseases
    • Fernandez-Medarde A and Santos E: RAS in cancer and developmental diseases. Genes Cancer 2: 344-358, 2011.
    • (2011) Genes Cancer , vol.2 , pp. 344-358
    • Fernandez-Medarde, A.1    Santos, E.2
  • 9
    • 79955669404 scopus 로고    scopus 로고
    • High prevalence of RAS mutations in RET-negative sporadic medullary thyroid carcinomas
    • Moura MM, Cavaco BM, Pinto AE and Leite V: High prevalence of RAS mutations in RET-negative sporadic medullary thyroid carcinomas. J Clin Endocrinol Metab 96: E863-868, 2011.
    • (2011) J Clin Endocrinol Metab , vol.96
    • Moura, M.M.1    Cavaco, B.M.2    Pinto, A.E.3    Leite, V.4
  • 15
    • 3242876311 scopus 로고    scopus 로고
    • BLAST: At the core of a powerful and diverse set of sequence analysis tools
    • McGinnis S and Madden TL: BLAST: At the core of a powerful and diverse set of sequence analysis tools. Nucleic Acids Res 32: W20-25, 2004.
    • (2004) Nucleic Acids Res , vol.32
    • McGinnis, S.1    Madden, T.L.2
  • 16
    • 77954065271 scopus 로고    scopus 로고
    • I-TASSER: A unified platform for automated protein structure and function prediction
    • Roy A, Kucukural A and Zhang Y: I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc 5: 725-738, 2010.
    • (2010) Nat Protoc , vol.5 , pp. 725-738
    • Roy, A.1    Kucukural, A.2    Zhang, Y.3
  • 18
    • 84863500976 scopus 로고    scopus 로고
    • The associations between RAS mutations and clinical characteristics in follicular thyroid tumors: New insights from a single center and a large patient cohort
    • Fukahori M, Yoshida A, Hayashi H, Yoshihara M, Matsukuma S, Sakuma Y, Koizume S, Okamoto N, Kondo T, Masuda M and Miyagi Y: The associations between RAS mutations and clinical characteristics in follicular thyroid tumors: New insights from a single center and a large patient cohort. Thyroid 22: 683-689, 2012.
    • (2012) Thyroid , vol.22 , pp. 683-689
    • Fukahori, M.1    Yoshida, A.2    Hayashi, H.3    Yoshihara, M.4    Matsukuma, S.5    Sakuma, Y.6    Koizume, S.7    Okamoto, N.8    Kondo, T.9    Masuda, M.10    Miyagi, Y.11
  • 19
    • 79953325102 scopus 로고    scopus 로고
    • Molecular analysis of thyroid tumors
    • Nikiforov YE: Molecular analysis of thyroid tumors. Mod Pathol 24(Suppl 2): S34-43, 2011.
    • (2011) Mod Pathol , vol.24 , Issue.SUPPL. 2
    • Nikiforov, Y.E.1
  • 20
    • 85047687680 scopus 로고    scopus 로고
    • Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of RAS mutations
    • Zhu Z, Gandhi M, Nikiforova MN, Fischer AH and Nikiforov YE: Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of RAS mutations. Am Clin Pathol 120: 71-77, 2003.
    • (2003) Am Clin Pathol , vol.120 , pp. 71-77
    • Zhu, Z.1    Gandhi, M.2    Nikiforova, M.N.3    Fischer, A.H.4    Nikiforov, Y.E.5
  • 21
    • 36749036721 scopus 로고    scopus 로고
    • Transformation efficiency of RASQ61 mutants linked to structural features of the switch regions in the presence of RAF
    • Buhrman G, Wink G and Mattos C: Transformation efficiency of RASQ61 mutants linked to structural features of the switch regions in the presence of RAF. Structure 15: 1618-1629, 2007.
    • (2007) Structure , vol.15 , pp. 1618-1629
    • Buhrman, G.1    Wink, G.2    Mattos, C.3
  • 22
    • 0022471217 scopus 로고
    • Biological and biochemical properties of human RASH genes mutated at codon 61
    • Der CJ, Finkel T and Cooper GM: Biological and biochemical properties of human RASH genes mutated at codon 61. Cell 44: 167-176, 1986.
    • (1986) Cell , vol.44 , pp. 167-176
    • Der, C.J.1    Finkel, T.2    Cooper, G.M.3
  • 23
    • 33745135726 scopus 로고    scopus 로고
    • Molecular genetic study comparing follicular variant versus classic papillary thyroid carcinomas: Association of N-RAS mutation in codon 61 with follicular variant
    • Di Cristofaro J, Marcy M, Vasko V, Sebag F, Fakhry N, Wynford-Thomas D and De Micco C: Molecular genetic study comparing follicular variant versus classic papillary thyroid carcinomas: Association of N-RAS mutation in codon 61 with follicular variant. Hum Pathol 37: 824-830, 2006.
    • (2006) Hum Pathol , vol.37 , pp. 824-830
    • Di Cristofaro, J.1    Marcy, M.2    Vasko, V.3    Sebag, F.4    Fakhry, N.5    Wynford-Thomas, D.6    De Micco, C.7
  • 24
    • 33645232222 scopus 로고    scopus 로고
    • Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas
    • Adeniran AJ, Zhu Z, Gandhi M, Steward DL, Fidler JP, Giordano TJ, Biddinger PW and Nikiforov YE: Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas. Am J Surg Pathol 30: 216-222, 2006.
    • (2006) Am J Surg Pathol , vol.30 , pp. 216-222
    • Adeniran, A.J.1    Zhu, Z.2    Gandhi, M.3    Steward, D.L.4    Fidler, J.P.5    Giordano, T.J.6    Biddinger, P.W.7    Nikiforov, Y.E.8
  • 25
    • 77956280558 scopus 로고    scopus 로고
    • Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs. Infiltrative) reveals distinct BRAF and RAS mutation patterns
    • Rivera M, Ricarte-Filho J, Knauf J, Shaha A, Tuttle M, Fagin JA and Ghossein RA: Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs. infiltrative) reveals distinct BRAF and RAS mutation patterns. Mod Pathol 23: 1191-1200, 2010.
    • (2010) Mod Pathol , vol.23 , pp. 1191-1200
    • Rivera, M.1    Ricarte-Filho, J.2    Knauf, J.3    Shaha, A.4    Tuttle, M.5    Fagin, J.A.6    Ghossein, R.A.7
  • 26
    • 77954022714 scopus 로고    scopus 로고
    • Genetic alterations in the RAS/RAF/ mitogen-activated protein kinase and phosphatidylinositol 3- kinase/AKT signaling pathways in the follicular variant of papillary thyroid carcinoma
    • Santarpia L, Myers JN, Sherman SI, Trimarchi F, Clayman GL and El-Naggar AK: Genetic alterations in the RAS/RAF/ mitogen-activated protein kinase and phosphatidylinositol 3- kinase/AKT signaling pathways in the follicular variant of papillary thyroid carcinoma. Cancer 116: 2974-2983, 2010.
    • (2010) Cancer , vol.116 , pp. 2974-2983
    • Santarpia, L.1    Myers, J.N.2    Sherman, S.I.3    Trimarchi, F.4    Clayman, G.L.5    El-Naggar, A.K.6
  • 27
    • 84884611267 scopus 로고    scopus 로고
    • Follicular Variant of Papillary Thyroid Carcinoma is a Unique Clinical Entity: A Population-Based Study of 10,740 Cases
    • Yu XM, Schneider DF, Leverson G, Chen H and Sippel RS: Follicular Variant of Papillary Thyroid Carcinoma is a Unique Clinical Entity: A Population-Based Study of 10,740 Cases. Thyroid 23: 1263-1268, 2013.
    • (2013) Thyroid , vol.23 , pp. 1263-1268
    • Yu, X.M.1    Schneider, D.F.2    Leverson, G.3    Chen, H.4    Sippel, R.S.5
  • 29
    • 33749012811 scopus 로고    scopus 로고
    • Follicular variant of papillary thyroid carcinoma: A clinicopathologic study of a problematic entity
    • Liu J, Singh B, Tallini G, Carlson DL, Katabi N, Shaha A, Tuttle RM and Ghossein RA: Follicular variant of papillary thyroid carcinoma: A clinicopathologic study of a problematic entity. Cancer 107: 1255-1264, 2006.
    • (2006) Cancer , vol.107 , pp. 1255-1264
    • Liu, J.1    Singh, B.2    Tallini, G.3    Carlson, D.L.4    Katabi, N.5    Shaha, A.6    Tuttle, R.M.7    Ghossein, R.A.8
  • 30
    • 54949150226 scopus 로고    scopus 로고
    • Aneuploidy and high S-phase as biomarkers of poor clinical outcome in poorly differentiated and anaplastic thyroid carcinoma
    • Pinto AE, Silva G, Banito A, Leite V and Soares J: Aneuploidy and high S-phase as biomarkers of poor clinical outcome in poorly differentiated and anaplastic thyroid carcinoma. Oncol Rep 20: 913-919, 2008.
    • (2008) Oncol Rep , vol.20 , pp. 913-919
    • Pinto, A.E.1    Silva, G.2    Banito, A.3    Leite, V.4    Soares, J.5
  • 32
    • 77955873741 scopus 로고    scopus 로고
    • Absence of BRAF, NRAS, KRAS, HRAS mutations, and RET /PTC gene rearrangements distinguishes dominant nodules in Hashimoto thyroiditis from papillary thyroid carcinomas
    • Sadow PM, Heinrich MC, Corless CL, Fletcher JA,\ and Nose V: Absence of BRAF, NRAS, KRAS, HRAS mutations, and RET /PTC gene rearrangements distinguishes dominant nodules in Hashimoto thyroiditis from papillary thyroid carcinomas. Endocr Pathol 21: 73-79, 2010.
    • (2010) Endocr Pathol , vol.21 , pp. 73-79
    • Sadow, P.M.1    Heinrich, M.C.2    Corless, C.L.3    Fletcher, J.A.4    Nose, V.5
  • 33
    • 36749003224 scopus 로고    scopus 로고
    • High prevalence of RET, RAS, and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population
    • Kang DY, Kim KH, Kim JM, Kim SH, Kim JY, Baik HW and Kim YS: High prevalence of RET, RAS, and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population. Thyroid 17: 1031-1038, 2007.
    • (2007) Thyroid , vol.17 , pp. 1031-1038
    • Kang, D.Y.1    Kim, K.H.2    Kim, J.M.3    Kim, S.H.4    Kim, J.Y.5    Baik, H.W.6    Kim, Y.S.7
  • 34
    • 0031783481 scopus 로고    scopus 로고
    • Prevalences of Gs alpha, ras, p53 mutations and ret/PTC rearrangement in differentiated thyroid tumours in a Korean population
    • Park KY, Koh JM, Kim YI, Park HJ, Gong G, Hong SJ and Ahn IM: Prevalences of Gs alpha, ras, p53 mutations and ret/PTC rearrangement in differentiated thyroid tumours in a Korean population. Clin Endocrinol 49: 317-323, 1998.
    • (1998) Clin Endocrinol , vol.49 , pp. 317-323
    • Park, K.Y.1    Koh, J.M.2    Kim, Y.I.3    Park, H.J.4    Gong, G.5    Hong, S.J.6    Ahn, I.M.7
  • 35
    • 4143129995 scopus 로고    scopus 로고
    • Selective occurrence of RAS mutations in benign and malignant thyroid follicular neoplasms in Taiwan
    • Liu RT, Hou CY, You HL, Huang CC, Hock L, Chou FF, Wang PW and Cheng JT: Selective occurrence of RAS mutations in benign and malignant thyroid follicular neoplasms in Taiwan. Thyroid 14: 616-621, 2004.
    • (2004) Thyroid , vol.14 , pp. 616-621
    • Liu, R.T.1    Hou, C.Y.2    You, H.L.3    Huang, C.C.4    Hock, L.5    Chou, F.F.6    Wang, P.W.7    Cheng, J.T.8
  • 36
    • 0029907969 scopus 로고    scopus 로고
    • Prevalence of activating RAS mutations in morphologically characterized thyroid nodules
    • Ezzat S, Zheng L, Kolenda J, Safarian A, Freeman JL and Asa SL: Prevalence of activating RAS mutations in morphologically characterized thyroid nodules. Thyroid 6: 409-416, 1996.
    • (1996) Thyroid , vol.6 , pp. 409-416
    • Ezzat, S.1    Zheng, L.2    Kolenda, J.3    Safarian, A.4    Freeman, J.L.5    Asa, S.L.6
  • 38
    • 0030024078 scopus 로고    scopus 로고
    • RAS oncogene mutations in thyroid tumors: Polymerase chain reaction-restriction-fragment-length polymorphism analysis from paraffin-embedded tissues
    • Capella G, Matias-Guiu X, Ampudia X, de Leiva A, Perucho M and Prat J: RAS oncogene mutations in thyroid tumors: Polymerase chain reaction-restriction- fragment-length polymorphism analysis from paraffin-embedded tissues. Diagn Mol Pathol 5: 45-52, 1996.
    • (1996) Diagn Mol Pathol , vol.5 , pp. 45-52
    • Capella, G.1    Matias-Guiu, X.2    Ampudia, X.3    De Leiva, A.4    Perucho, M.5    Prat, J.6
  • 39
    • 0025185363 scopus 로고
    • Point mutations of RAS oncogenes are an early event in thyroid tumorigenesis
    • Namba H, Rubin SA and Fagin JA: Point mutations of RAS oncogenes are an early event in thyroid tumorigenesis. Mol Endocrinol 4: 1474-1479, 1990.
    • (1990) Mol Endocrinol , vol.4 , pp. 1474-1479
    • Namba, H.1    Rubin, S.A.2    Fagin, J.A.3
  • 40
    • 0029097741 scopus 로고
    • Point mutations of RAS and Gs alpha subunit genes in thyroid tumors
    • Horie H, Yokogoshi Y, Tsuyuguchi M and Saito S: Point mutations of RAS and Gs alpha subunit genes in thyroid tumors. Jpn J Cancer Res 86: 737-742, 1995.
    • (1995) Jpn J Cancer Res , vol.86 , pp. 737-742
    • Horie, H.1    Yokogoshi, Y.2    Tsuyuguchi, M.3    Saito, S.4
  • 42
    • 39149083748 scopus 로고    scopus 로고
    • New insights in thyroid follicular cell biology and its impact in thyroid cancer therapy
    • Riesco-Eizaguirre G and Santisteban P: New insights in thyroid follicular cell biology and its impact in thyroid cancer therapy. Endocr Relat Cancer 14: 957-977, 2007.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 957-977
    • Riesco-Eizaguirre, G.1    Santisteban, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.