Prevalence of activating ras mutations in morphologically characterized thyroid nodules

Thyroid

Volumn 6, Issue 5, 1996, Pages 409-416

  Ezzat, Shereen ^a,b   Zheng, Lei ^a   Kolenda, Jacek ^a   Safarian, Anehita ^a   Freeman, Jeremy L ^a   Asa, Sylvia L ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; MALE; NODULAR GOITER; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE RAS; PRIORITY JOURNAL; THYROID ADENOMA; THYROID CARCINOMA; THYROID NODULE; THYROID PAPILLARY CARCINOMA;

EID: 0029907969     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/thy.1996.6.409     Document Type: Article

References (32)

1. Murray D 1991 The thyroid gland. In: Kovacs K, Asa SL (eds) Functional Endocrine Pathology. Blackwell Scientific Publications, Boston, pp 293-374.
2. LiVolsi VA 1990 Surgical Pathology of the Thyroid. W.B. Saunders, Philadelphia, PA.
3. Rosai J, Carcangiu ML, DeLellis RA 1992 Tumors of the Thyroid Gland. Atlas of Tumor Pathology, Third Series, Fascicle 5. Armed Forces Institute of Pathology, Washington, D.C.,
4. Weinberg RA 1991 Tumor suppressor genes. Science 254:1138-1146.
5. Pai EF, Kabsch W, Krengel U, Holmes KG, John J, Wittinghofer A 1989 Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation. Nature (London) 341:209-214.
6. Fagin JA 1992 Genetic basis of endocrine disease 3. Molecular defects in thyroid gland neoplasia. J Clin Endocrinol Metab 75:1398-1400.
7. Baxter JD 1991 Advances in molecular biology. Potential impact on diagnosis and treatment of disorders of the thyroid. Med Clin North Am 75:41-59.
8. Suarez HG, du Villard JA, Severino, Caillou B, Schlumberger M, Tubiana M, Parmentier C, Monier R 1990 Presence of mutations in all three ras genes in human thyroid tumors. Oncogene 5:565-570.
9. Lemoine NR, Mayall ES, Wyllie FS, Williams ED, Goyns M, Stringer B, Wynford-Thomas D 1989 High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis. Oncogene 4:159-164.
10. Suarez HG, du Villard JA, Caillou B, Schlumberger M, Tubiana M, Parmentier C, Monier R 1988 Detection of activated ras oncogenes in human thyroid carcinomas. Oncogene 2:403-406.
11. Lemoine NR, Mayall ES, Wyllie FS, Farr CJ, Hughes D, Padua RA, Thurston V, Williams ED, Wynford-Thomas D 1988 Activated ras oncogenes in human thyroid cancers. Cancer Res 48:4459-4463.
12. Farid NR, Shi Y, Zou M 1994 Molecular basis of thyroid cancer. Endocr Rev 15:202-232.
13. Cotton RGH 1993 Current methods of mutation detection. Mutat Res 285:125-144.
14. Suzuki Y, Orita M, Shiraishi M, Hayashi K, Sekiya T 1990 Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene 5:1037-1043.
15. Druker BJ, Mamon H, Roberts TM 1989 Oncogenes, growth factors, and signal transduction. N Engl J Med 321:1383-1391.
16. Namba H, Rubin SA, Fagin FA 1990 Point mutations of ras oncogenes are an early event in thyroid tumorigenesis. Mol Endocrinol 4:1474-1479.
17. Schark C, Fulton N, Jacoby RF, Westbrook CA, Straus FH, II., Kaplan EL 1990 N-ras 61 oncogene mutations in Hürthle cell tumors. Surgery 108:994-1000.
18. Karga H, Lee J-K, Vickery AL, Jr., Thor A, Gaz RD, Jameson JL 1991 Ras oncogene mutations in benign and malignant thyroid neoplasms. J Clin Endocrinol Metab 73:832-836.
19. Wright PA, Lemoine NR, Mayall ES, Wyllie FS, Hughes D, Williams ED, Wynford-Thomas D 1989 Papillary and follicular thyroid carcinomas show a different pattern of ras oncogene mutation. Br J Cancer 60:576-577.
20. Shi Y, Zou M, Schmidt H, Juhasz F, Stensky V, Robb D, Farid NR 1991 High rates of ras codon 61 mutation in thyroid tumors in an iodide-deficient area. Cancer Res 51:2690-2693.
21. Wright PA, Williams ED, Lemoine NR, Wynford-Thomas D 1991 Radiation-associated and 'spontaneous' human thyroid carcinomas show a different pattern of ras oncogene mutation. Oncogene 6:471-473.
22. Grompe M 1993 The rapid detection of unknown mutations in nucleic acids. Nature Genet 5:111-117.
23. Apel RL, Ezzat S, Bapat B, Pan N, LiVolsi VA, Asa SL 1995 Clonality of thyroid nodules in sporadic goiter. Diag Mol Pathol 4:113-121.
24. Thomas GA, Williams D, Williams ED 1989 The clonal origin of thyroid nodules and adenomas. Am J Pathol 134:141-147.
25. Namba H, Matsuo K, Fagin JA 1990 Clonal composition of benign and malignant human thyroid tumors. J Clin Invest 86:120-125.
26. Fey MF, Peter H-J, Hinds HL, Zimmermann A, Liechti-Galiati S, Gerber H, Studer H, Tobler A 1992 Clonal analysis of human tumors with M27β, a highly informative polymorphic X chromosomal probe. J Clin Invest 89:1438-1444.
27. Papadimitriou K, Yiagnisis M, Tolis G, Spandidos DA 1988 Immunohistochemical analysis of the ras oncogene protein product in human thyroid neoplasms. Anticancer Res 5:1223-1228.
28. McConahey WM, Hay ID, Woolner LB, van Heerden JA, Taylor WF 1986 Papillary thyroid cancer treated at the Mayo Clinic, 1946 through 1970: Initial manifestations, pathologic findings, therapy, and outcome. Mayo Clin Proc 61:978-996.
29. Mazzaferri EL, Jhiang SM 1994 Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med 97:418-428.
30. Namba H, Gutman RA, Matsuo K, Alvarez A, Fagin JA 1990 H-ras protooncogene mutations in human thyroid neoplasms. J Clin Endocrinol Metab 71:223-229.
31. Goretzki PE, Lyons J, Stacy-Phipps S, Rosenau W, Demeure M, Clark OH, McCormick F, Röher H-D, Bourne HR 1992 Mutational activation of RAS and GSP oncogenes in differentiated thyroid cancer and their biological implications. World J Surg 16:576-582.
32. Schark C, Fulton N, Yashiro T, Stanislav G, Jacoby R, Strauss FH, II., Dytch H, Bibbo M, Kaplan EL 1992 The value of measurement of RAS oncogenes and nuclear DNA analysis in the diagnosis of Hürthle cell tumors of the thyroid. World J Surg 16:745-752.