-
1
-
-
84855353573
-
Heart disease and stroke statistics-2012 update: A report from the American Heart Association
-
Roger, V. L., A. S. Go, D. M. Lloyd-Jones, E. J. Benjamin, J. D. Berry, W. B. Borden, D. M. Bravata, S. Dai, E. S. Ford, C. S. Fox, et al . 2012 . Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation . 125 : e2-e220 .
-
(2012)
Circulation
, vol.125
-
-
Roger, V.L.1
Go, A.S.2
Lloyd-Jones, D.M.3
Benjamin, E.J.4
Berry, J.D.5
Borden, W.B.6
Bravata, D.M.7
Dai, S.8
Ford, E.S.9
Fox, C.S.10
-
2
-
-
72949132104
-
Factors of risk in the development of coronary heart disease-six year follow-up experience. The Framingham Study
-
Kannel, W. B., T. R. Dawber, A. Kagan, N. Revotskie, and J. I. Stokes . 1961 . Factors of risk in the development of coronary heart disease-six year follow-up experience. The Framingham Study. Ann. Intern. Med. 55 : 33-50 .
-
(1961)
Ann. Intern. Med
, vol.55
, pp. 33-50
-
-
Kannel, W.B.1
Dawber, T.R.2
Kagan, A.3
Revotskie, N.4
Stokes, J.I.5
-
3
-
-
0027512278
-
Genetic and environmental infl uences on serum lipid levels in twins
-
Heller, D.A, U . de Faire, N. L. Pedersen, G. Dahlen, and G. E. McClearn . 1993 . Genetic and environmental infl uences on serum lipid levels in twins. N. Engl. J. Med. 328 : 1150-1156 .
-
(1993)
N. Engl. J. Med
, vol.328
, pp. 1150-1156
-
-
Heller, D.A.1
Pedersen, N.L.2
Dahlen, G.3
McClearn, G.E.4
-
4
-
-
33644810250
-
Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels
-
Boekholdt, S. M., O. W. Souverein, M. W. Tanck, G. K. Hovingh, J. A. Kuivenhoven, R. I. Peters, H. Jansen, P. M. Schiffers, E. E. Van der Wall, P. A. Doevendans, et al . 2006 . Common variants of multiple genes that control reverse cholesterol transport together explain only a minor part of the variation of HDL cholesterol levels. Clin. Genet. 69 : 263-270 .
-
(2006)
Clin. Genet
, vol.69
, pp. 263-270
-
-
Boekholdt, S.M.1
Souverein, O.W.2
Tanck, M.W.3
Hovingh, G.K.4
Kuivenhoven, J.A.5
Peters, R.I.6
Jansen, H.7
Schiffers, P.M.8
Van Der Wall, E.E.9
Doevendans, P.A.10
-
5
-
-
38649132270
-
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
-
Kathiresan, S., O. Melander, C. Guiducci, A. Surti, N. P. Burtt, J. Rieder, G. M. Cooper, C. Roos, B. F. Voight, A. S. Havulinna, et al . 2008 . Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat. Genet. 40 : 189-197 .
-
(2008)
Nat. Genet
, vol.40
, pp. 189-197
-
-
Kathiresan, S.1
Melander, O.2
Guiducci, C.3
Surti, A.4
Burtt, N.P.5
Rieder, J.6
Cooper, G.M.7
Roos, C.8
Voight, B.F.9
Havulinna, A.S.10
-
6
-
-
38649125868
-
Newly identifi ed loci that infl uence lipid concentrations and risk of coronary artery disease
-
Willer, C. J., S. Sanna, A. U. Jackson, A. Scuteri, L. L. Bonnycastle, R. Clarke, S. C. Heath, N. J. Timpson, S. S. Najjar, H. M. Stringham, et al . 2008 . Newly identifi ed loci that infl uence lipid concentrations and risk of coronary artery disease. Nat. Genet. 40 : 161-169 .
-
(2008)
Nat. Genet
, vol.40
, pp. 161-169
-
-
Willer, C.J.1
Sanna, S.2
Jackson, A.U.3
Scuteri, A.4
Bonnycastle, L.L.5
Clarke, R.6
Heath, S.C.7
Timpson, N.J.8
Najjar, S.S.9
Stringham, H.M.10
-
7
-
-
58149161560
-
Loci infl uencing lipid levels and coronary heart disease risk in 16 European population cohorts
-
Aulchenko, Y. S., S. Ripatti, I. Lindqvist, D. Boomsma, I. M. Heid, P. P. Pramstaller, B. W. Penninx, A. C. Janssens, J. F. Wilson, T. Spector, et al. 2009 . Loci infl uencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat. Genet. 41 : 47-55 .
-
(2009)
Nat. Genet
, vol.41
, pp. 47-55
-
-
Aulchenko, Y.S.1
Ripatti, S.2
Lindqvist, I.3
Boomsma, D.4
Heid, I.M.5
Pramstaller, P.P.6
Penninx, B.W.7
Janssens, A.C.8
Wilson, J.F.9
Spector, T.10
-
8
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich, T. M., K. Musunuru, A. V. Smith, A. C. Edmondson, I. M. Stylianou, M. Koseki, J. P. Pirruccello, S. Ripatti, D. I. Chasman, C. J. Willer, et al . 2010 . Biological, clinical and population relevance of 95 loci for blood lipids. Nature . 466 : 707-713 .
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
Edmondson, A.C.4
Stylianou, I.M.5
Koseki, M.6
Pirruccello, J.P.7
Ripatti, S.8
Chasman, D.I.9
Willer, C.J.10
-
9
-
-
84867839391
-
Genetics of coronary artery disease: Genome-wide association studies and beyond
-
Prins, B. P., V. Lagou, F. W. Asselbergs, H. Snieder, and J. Fu . 2012 . Genetics of coronary artery disease: Genome-wide association studies and beyond. Atherosclerosis . 225 : 1-10 .
-
(2012)
Atherosclerosis
, vol.225
, pp. 1-10
-
-
Prins, B.P.1
Lagou, V.2
Asselbergs, F.W.3
Snieder, H.4
Fu, J.5
-
10
-
-
68649101805
-
Common vs. Rare allele hypotheses for complex diseases
-
Schork, N. J., S. S. Murray, K. A. Frazer, and E. J. Topol . 2009 . Common vs. rare allele hypotheses for complex diseases. Curr. Opin. Genet. Dev. 19 : 212-219 .
-
(2009)
Curr. Opin. Genet. Dev
, vol.19
, pp. 212-219
-
-
Schork, N.J.1
Murray, S.S.2
Frazer, K.A.3
Topol, E.J.4
-
11
-
-
32444441330
-
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels
-
Cohen, J. C., A. Pertsemlidis, S. Fahmi, S. Esmail, G. L. Vega, S. M. Grundy, and H. H. Hobbs . 2006 . Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. Proc. Natl. Acad. Sci. USA . 103 : 1810-1815 .
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 1810-1815
-
-
Cohen, J.C.1
Pertsemlidis, A.2
Fahmi, S.3
Esmail, S.4
Vega, G.L.5
Grundy, S.M.6
Hobbs, H.H.7
-
12
-
-
3843056691
-
Multiple rare alleles contribute to low plasma levels of HDL cholesterol
-
Cohen, J. C., R. S. Kiss, A. Pertsemlidis, Y. L. Marcel, R. McPherson, and H. H. Hobbs . 2004 . Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science . 305 : 869-872 .
-
(2004)
Science
, vol.305
, pp. 869-872
-
-
Cohen, J.C.1
Kiss, R.S.2
Pertsemlidis, A.3
Marcel, Y.L.4
McPherson, R.5
Hobbs, H.H.6
-
13
-
-
77955070766
-
Excess of rare variants in genes identifi ed by genome-wide association study of hypertriglyceridemia
-
Johansen, C. T., J. Wang, M. B. Lanktree, H. Cao, A. D. McIntyre, M. R. Ban, R. A. Martins, B. A. Kennedy, R. G. Hassell, M. E. Visser, et al . 2010 . Excess of rare variants in genes identifi ed by genome-wide association study of hypertriglyceridemia. Nat. Genet. 42 : 684-687 .
-
(2010)
Nat. Genet
, vol.42
, pp. 684-687
-
-
Johansen, C.T.1
Wang, J.2
Lanktree, M.B.3
Cao, H.4
McIntyre, A.D.5
Ban, M.R.6
Martins, R.A.7
Kennedy, B.A.8
Hassell, R.G.9
Visser, M.E.10
-
14
-
-
84860856675
-
Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia
-
Johansen, C. T., J. Wang, A. D. McIntyre, R. A. Martins, M. R. Ban, M. B. Lanktree, M. W. Huff, M. Peterfy, M. Mehrabian, A. J. Lusis, et al . 2012 . Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia. Circ Cardiovasc Genet . 5 : 66-72 .
-
(2012)
Circ Cardiovasc Genet
, vol.5
, pp. 66-72
-
-
Johansen, C.T.1
Wang, J.2
McIntyre, A.D.3
Martins, R.A.4
Ban, M.R.5
Lanktree, M.B.6
Huff, M.W.7
Peterfy, M.8
Mehrabian, M.9
Lusis, A.J.10
-
15
-
-
79957506175
-
Strategic approaches to unraveling genetic causes of cardiovascular diseases
-
Marian, A. J., and J. Belmont . 2011 . Strategic approaches to unraveling genetic causes of cardiovascular diseases. Circ. Res. 108 : 1252-1269 .
-
(2011)
Circ. Res
, vol.108
, pp. 1252-1269
-
-
Marian, A.J.1
Belmont, J.2
-
16
-
-
0029920693
-
Lipoprotein lipase and lipolysis: Central roles in lipoprotein metabolism and atherogenesis
-
Goldberg, I. J. 1996 . Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. J. Lipid Res. 37 : 693-707 .
-
(1996)
J. Lipid Res
, vol.37
, pp. 693-707
-
-
Goldberg, I.J.1
-
17
-
-
0023423565
-
Human genes involved in lipolysis of plasma lipoproteins: Mapping of loci for lipoprotein lipase to 8p22 andhepatic lipase to 15q21
-
Sparkes, R. S., S. Zollman, I. Klisak, T. G. Kirchgessner, M. C. Komaromy, T. Mohandas, M. C. Schotz, and A. J. Lusis . 1987 . Human genes involved in lipolysis of plasma lipoproteins: mapping of loci for lipoprotein lipase to 8p22 andhepatic lipase to 15q21. Genomics . 1 : 138-144 .
-
(1987)
Genomics
, vol.1
, pp. 138-144
-
-
Sparkes, R.S.1
Zollman, S.2
Klisak, I.3
Kirchgessner, T.G.4
Komaromy, M.C.5
Mohandas, T.6
Schotz, M.C.7
Lusis, A.J.8
-
18
-
-
0032914885
-
Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins
-
Henderson, H. E., J. J. Kastelein, A. H. Zwinderman, H. E. Henderson, J. J. Kastelein, A. H. Zwinderman, E. Gagne, J. W. Jukema, P. W. Reymer, B. E. Groenemeyer, et al . 1999 . Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins. J. Lipid Res. 40 : 735-743 .
-
(1999)
J. Lipid Res
, vol.40
, pp. 735-743
-
-
Henderson, H.E.1
Kastelein, J.J.2
Zwinderman, A.H.3
Henderson, H.E.4
Kastelein, J.J.5
Zwinderman, A.H.6
Gagne, E.7
Jukema, J.W.8
Reymer, P.W.9
Groenemeyer, B.E.10
-
19
-
-
33646590329
-
Serum lipoprotein lipase concentration and risk for future coronary artery disease: The EPIC-Norfolk prospective population study
-
Rip, J., M. C. Nierman, N. J. Wareham, R. Luben, S. A. Bingham, N. E. Day, J. N. van Miert, B. A. Hutten, J. J. Kastelein, J. A. Kuivenhove, et al . 2006 . Serum lipoprotein lipase concentration and risk for future coronary artery disease: the EPIC-Norfolk prospective population study. Arterioscler. Thromb. Vasc. Biol. 26 : 637-642 .
-
(2006)
Arterioscler. Thromb. Vasc. Biol
, vol.26
, pp. 637-642
-
-
Rip, J.1
Nierman, M.C.2
Wareham, N.J.3
Luben, R.4
Bingham, S.A.5
Day, N.E.6
Van Miert, J.N.7
Hutten, B.A.8
Kastelein, J.J.9
Kuivenhove, J.A.10
-
20
-
-
59649092852
-
Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: A systematic in-depth review
-
Boes, E., S. Coassin, B. Kollerits, I. M. Heid, and F. Kronenberg . 2009 . Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. Exp. Gerontol. 44 : 136-160 .
-
(2009)
Exp. Gerontol
, vol.44
, pp. 136-160
-
-
Boes, E.1
Coassin, S.2
Kollerits, B.3
Heid, I.M.4
Kronenberg, F.5
-
21
-
-
0024541239
-
Methods and prevalence of non-insulin-dependent diabetes mellitus in a biethnic Colorado population. The San Luis Valley Diabetes Study
-
Hamman, R. F., J. A. Marshall, J. Baxter, L. B. Kahn, E. J. Mayer, M. Orleans, J. R. Murphy, and D. C. Lezotte . 1989 . Methods and prevalence of non-insulin-dependent diabetes mellitus in a biethnic Colorado population. The San Luis Valley Diabetes Study. Am. J. Epidemiol. 129 : 295-311 .
-
(1989)
Am. J. Epidemiol
, vol.129
, pp. 295-311
-
-
Hamman, R.F.1
Marshall, J.A.2
Baxter, J.3
Kahn, L.B.4
Mayer, E.J.5
Orleans, M.6
Murphy, J.R.7
Lezotte, D.C.8
-
22
-
-
0027897598
-
Is the risk of coronary heart disease lower in Hispanics than in non-Hispanic whites?
-
Rewers, M., S. M. Shetterly, S. Hoag, J. Baxter, J. Marshall, and R. F. Hamman . 1993 . Is the risk of coronary heart disease lower in Hispanics than in non-Hispanic whites? The San Luis Valley Diabetes Study. Ethn. Dis. 3 : 44-54 .
-
(1993)
The San Luis Valley Diabetes Study Ethn. Dis
, vol.3
, pp. 44-54
-
-
Rewers, M.1
Shetterly, S.M.2
Hoag, S.3
Baxter, J.4
Marshall, J.5
Hamman, R.F.6
-
23
-
-
72149101536
-
Association of a common G6PC2 variant with fasting plasma glucose levels in non-diabetic individuals
-
Demirci, F. Y., A. S. Dressen, R. F. Hamman, C. H. Bunker, C. M. Kammerer, and M. I. Kamboh . 2010 . Association of a common G6PC2 variant with fasting plasma glucose levels in non-diabetic individuals. Ann. Nutr. Metab. 56 : 59-64 .
-
(2010)
Ann. Nutr. Metab
, vol.56
, pp. 59-64
-
-
Demirci, F.Y.1
Dressen, A.S.2
Hamman, R.F.3
Bunker, C.H.4
Kammerer, C.M.5
Kamboh, M.I.6
-
24
-
-
0015719916
-
Preparation and properties of a cholesterol oxidase from Nocardia wp. and its application to the enzymatic assay of total cholesterol in serum
-
Richmond, W. 1973 . Preparation and properties of a cholesterol oxidase from Nocardia wp. and its application to the enzymatic assay of total cholesterol in serum. Clin. Chem. 19 : 1350-1356 .
-
(1973)
Clin. Chem
, vol.19
, pp. 1350-1356
-
-
Richmond, W.1
-
25
-
-
0032478227
-
Racial differences in the distribution of a low density lipoprotein receptor-related protein (LRP) polymorphism and its association with serum lipoprotein, lipid and apolipoprotein levels
-
Harris, M. R., C. H. Bunker, R. F. Hamman, D. K. Sanghera, C. E. Aston, and M. I. Kamboh . 1998 . Racial differences in the distribution of a low density lipoprotein receptor-related protein (LRP) polymorphism and its association with serum lipoprotein, lipid and apolipoprotein levels. Atherosclerosis . 137 : 187-195 .
-
(1998)
Atherosclerosis
, vol.137
, pp. 187-195
-
-
Harris, M.R.1
Bunker, C.H.2
Hamman, R.F.3
Sanghera, D.K.4
Aston, C.E.5
Kamboh, M.I.6
-
26
-
-
0015348189
-
Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge
-
Friedewald, W. T., R. I. Levy, and D. S. Fredrickson . 1972 . Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin. Chem. 18 : 499-502 .
-
(1972)
Clin. Chem
, vol.18
, pp. 499-502
-
-
Friedewald, W.T.1
Levy, R.I.2
Fredrickson, D.S.3
-
27
-
-
17344364213
-
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
-
Nickerson, D. A., S. L. Taylor, K. M. Weiss, A. G. Clark, R. G. Hutchinson, J. Stengard, V. Salomaa, E. Vartiainen, E. Boerwinkle, and C. F. Sing . 1998 . DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat. Genet. 19 : 233-240 .
-
(1998)
Nat. Genet
, vol.19
, pp. 233-240
-
-
Nickerson, D.A.1
Taylor, S.L.2
Weiss, K.M.3
Clark, A.G.4
Hutchinson, R.G.5
Stengard, J.6
Salomaa, V.7
Vartiainen, E.8
Boerwinkle, E.9
Sing, C.F.10
-
28
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett, J. C. B., J. Fry, J. Maller, and M. J. Daly . 2005 . Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics . 21 : 263-265 .
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.B.1
Fry, J.2
Maller, J.3
Daly, M.J.4
-
29
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini, Y., and Y. Hochberg . 1995 . Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B . 57 : 289-300 .
-
(1995)
J. R. Stat. Soc. Ser. B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
30
-
-
77955064853
-
A versatile gene-based test for genome-wide association studies
-
Liu, J. Z., A. F. McRae, D. R. Nyholt, S. E. Medland, N. R. Wray, K. M. Brown, N. K. Hayward, G. W. Montgomery, P. M. Visscher, N.G. Martin, et al. 2010 . A versatile gene-based test for genome-wide association studies. Am. J. Hum. Genet. 87 : 139-145 .
-
(2010)
Am. J. Hum. Genet
, vol.87
, pp. 139-145
-
-
Liu, J.Z.1
McRae, A.F.2
Nyholt, D.R.3
Medland, S.E.4
Wray, N.R.5
Brown, K.M.6
Hayward, N.K.7
Montgomery, G.W.8
Visscher, P.M.9
Martin, N.G.10
-
31
-
-
0041672374
-
Estimation and tests of haplotypeenvironment interaction when linkage phase is ambiguous
-
Lake, S. L., H. Lyon, K. Tantisira, E. K. Silverman, S. T. Weiss, N. M. Laird, and D. J. Schaid . 2003 . Estimation and tests of haplotypeenvironment interaction when linkage phase is ambiguous. Hum. Hered. 55 : 56-65 .
-
(2003)
Hum. Hered
, vol.55
, pp. 56-65
-
-
Lake, S.L.1
Lyon, H.2
Tantisira, K.3
Silverman, E.K.4
Weiss, S.T.5
Laird, N.M.6
Schaid, D.J.7
-
32
-
-
50949095168
-
Methods for detecting associations with rare variants for common diseases: Application to analysis of sequence data
-
Li, B., and S. M. Leal . 2008 . Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am. J. Hum. Genet. 83 : 311-321 .
-
(2008)
Am. J. Hum. Genet
, vol.83
, pp. 311-321
-
-
Li, B.1
Leal, S.M.2
-
33
-
-
84864953892
-
Optimal tests for rare variant effects in sequencing association studies
-
Lee, S., M. C. Wu, and X. Lin . 2012 . Optimal tests for rare variant effects in sequencing association studies. Biostatistics . 13 : 762-775 .
-
(2012)
Biostatistics
, vol.13
, pp. 762-775
-
-
Lee, S.1
Wu, M.C.2
Lin, X.3
-
34
-
-
0027406054
-
Two DNA polymorphisms in the lipoprotein lipase gene and their associations with factors related to cardiovascular disease
-
Ahn, Y. I., M. I. Kamboh, R. F. Hamman, S. A. Cole, and R. E. Ferrell . 1993 . Two DNA polymorphisms in the lipoprotein lipase gene and their associations with factors related to cardiovascular disease. J. Lipid Res. 34 : 421-428 .
-
(1993)
J. Lipid Res
, vol.34
, pp. 421-428
-
-
Ahn, Y.I.1
Kamboh, M.I.2
Hamman, R.F.3
Cole, S.A.4
Ferrell, R.E.5
-
35
-
-
0033776844
-
Genetic screening of the lipoprotein lipasegene for mutations associated with high triglyceride/low hdl-cholesterol levels
-
Razzaghi, H., C. E. Aston, R. F. Hamman, and M. I. Kamboh . 2000 . Genetic screening of the lipoprotein lipasegene for mutations associated with high triglyceride/low hdl-cholesterol levels. Hum. Genet. 107 : 257-267 .
-
(2000)
Hum. Genet
, vol.107
, pp. 257-267
-
-
Razzaghi, H.1
Aston, C.E.2
Hamman, R.F.3
Kamboh, M.I.4
-
36
-
-
57149112963
-
Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: A HuGE association review and meta-analysis
-
Sagoo, G. S., I. Tatt, G. Salanti, A. S. Butterworth, N. Sarwar, M. van Maarle, J. W. Jukema, B. Wiman, J. J. Kastelein, A. M. Bennet, et al . 2008 . Seven lipoprotein lipase gene polymorphisms, lipid fractions, and coronary disease: a HuGE association review and meta-analysis. Am. J. Epidemiol. 168 : 1233-1246 .
-
(2008)
Am. J. Epidemiol
, vol.168
, pp. 1233-1246
-
-
Sagoo, G.S.1
Tatt, I.2
Salanti, G.3
Butterworth, A.S.4
Sarwar, N.5
Van Maarle, M.6
Jukema, J.W.7
Wiman, B.8
Kastelein, J.J.9
Bennet, A.M.10
-
37
-
-
84865712382
-
Annotation of functional variation in personal genomes using RegulomeDB
-
Boyle, A. P., E. L. Hong, M. Hariharan, Y. Cheng, M. A. Schaub, M. Kasowski, K. J. Karczewski, J. Park, B. C. Hitz, S. Weng, et al . 2012 . Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22 : 1790-1797 .
-
(2012)
Genome Res
, vol.22
, pp. 1790-1797
-
-
Boyle, A.P.1
Hong, E.L.2
Hariharan, M.3
Cheng, Y.4
Schaub, M.A.5
Kasowski, M.6
Karczewski, K.J.7
Park, J.8
Hitz, B.C.9
Weng, S.10
-
38
-
-
0345620788
-
Hypertriglyceridemia: Changes in the plasma lipoproteins associated with an increased risk of cardiovascular disease
-
Brewer, H. B., Jr . 1999 . Hypertriglyceridemia: changes in the plasma lipoproteins associated with an increased risk of cardiovascular disease. Am. J. Cardiol. 83 : 3F-12F .
-
(1999)
Am. J. Cardiol.
, vol.83
-
-
Brewer Jr., H.B.1
-
39
-
-
34249694670
-
Impact of lowering triglycerides on raising HDL-C in hypertriglyceridemic and nonhypertriglyceridemic subjects
-
Miller, M., P. Langenberg, and S. Havas . 2007 . Impact of lowering triglycerides on raising HDL-C in hypertriglyceridemic and nonhypertriglyceridemic subjects. Int. J. Cardiol. 119 : 192-195 .
-
(2007)
Int. J. Cardiol
, vol.119
, pp. 192-195
-
-
Miller, M.1
Langenberg, P.2
Havas, S.3
-
40
-
-
45449094240
-
Genetic screening of the LPL gene in hypertriglyceridaemic patients
-
Wright, W. T., I. S. Young, D. P. Nicholls, and C. A. Graham . 2008 . Genetic screening of the LPL gene in hypertriglyceridaemic patients. Atherosclerosis . 199 : 187-192 .
-
(2008)
Atherosclerosis
, vol.199
, pp. 187-192
-
-
Wright, W.T.1
Young, I.S.2
Nicholls, D.P.3
Graham, C.A.4
-
41
-
-
49749147556
-
Functional signifi cance of lipoprotein lipase HindIII polymorphism associated with the risk of coronary artery disease
-
Chen, Q., H. Razzaghi, F. Y. Demirci, and M. I. Kamboh . 2008 . Functional signifi cance of lipoprotein lipase HindIII polymorphism associated with the risk of coronary artery disease. Atherosclerosis . 200 : 102-108 .
-
(2008)
Atherosclerosis
, vol.200
, pp. 102-108
-
-
Chen, Q.1
Razzaghi, H.2
Demirci, F.Y.3
Kamboh, M.I.4
-
42
-
-
84872346018
-
Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site
-
Richardson, K., J. A. Nettleton, N. Rotllan, T. Tanaka, C. E. Smith, C. Q. Lai, L. D. Parnell, Y. C. Lee, J. Lahti, R. N. Lemaitre, et al . 2013 . Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. Am. J. Hum. Genet. 92 : 5-14 .
-
(2013)
Am. J. Hum. Genet
, vol.92
, pp. 5-14
-
-
Richardson, K.1
Nettleton, J.A.2
Rotllan, N.3
Tanaka, T.4
Smith, C.E.5
Lai, C.Q.6
Parnell, L.D.7
Lee, Y.C.8
Lahti, J.9
Lemaitre, R.N.10
-
43
-
-
0031955802
-
Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: The European Atherosclerosis Research Study (EARS)
-
Humphries, S. E., V. Nicaud, J. Margalef, L. Tiret, and P. J. Talmud . 1998 . Lipoprotein lipase gene variation is associated with a paternal history of premature coronary artery disease and fasting and postprandial plasma triglycerides: the European Atherosclerosis Research Study (EARS). Arterioscler. Thromb. Vasc. Biol. 18 : 526-534 .
-
(1998)
Arterioscler. Thromb. Vasc. Biol
, vol.18
, pp. 526-534
-
-
Humphries, S.E.1
Nicaud, V.2
Margalef, J.3
Tiret, L.4
Talmud, P.J.5
-
44
-
-
0033536024
-
Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis
-
Wittrup, H. H., A. Tybjaerg-Hansen, and B. G. Nordestgaard . 1999 . Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis. Circulation . 99 : 2901-2907 .
-
(1999)
Circulation
, vol.99
, pp. 2901-2907
-
-
Wittrup, H.H.1
Tybjaerg-Hansen, A.2
Nordestgaard, B.G.3
-
45
-
-
33646029975
-
Association of lipoprotein lipase Hind III and ser 447 ter polymorphisms with dyslipidemia in Asian Indians
-
Radha, V., V. Mohan, R. Vidya, A. K. Ashok, R. Deepa, and R. A. Mathias . 2006 . Association of lipoprotein lipase Hind III and Ser 447 Ter polymorphisms with dyslipidemia in Asian Indians. Am. J. Cardiol. 97 : 1337-1342 .
-
(2006)
Am. J. Cardiol
, vol.97
, pp. 1337-1342
-
-
Radha, V.1
Mohan, V.2
Vidya, R.3
Ashok, A.K.4
Deepa, R.5
Mathias, R.A.6
-
46
-
-
34848825888
-
Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modifi ed by dietary fat intake in African American and White adults
-
Nettleton, J. A., L. M. Steffen, C. M. Ballantyne, E. Boerwinkle, and A. R. Folsom . 2007 . Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modifi ed by dietary fat intake in African American and White adults. Atherosclerosis . 194 : e131-e140 .
-
(2007)
Atherosclerosis
, vol.194
-
-
Nettleton, J.A.1
Steffen, L.M.2
Ballantyne, C.M.3
Boerwinkle, E.4
Folsom, A.R.5
-
47
-
-
34347353158
-
The S447X variant of lipoprotein lipase gene is associated with metabolic syndrome and lipid levels among Turks
-
Komurcu-Bayrak, E, A. Onat, M. Poda, S. E. Humphries, J. Acharya, G. Hergenc, N. Coban, G. Can, and N. Erginel-Unaltuna. 2007 . The S447X variant of lipoprotein lipase gene is associated with metabolic syndrome and lipid levels among Turks. Clin. Chim. Acta . 383 : 110-115 .
-
(2007)
Clin. Chim. Acta
, vol.383
, pp. 110-115
-
-
Komurcu-Bayrak, E.1
Onat, A.2
Poda, M.3
Humphries, S.E.4
Acharya, J.5
Hergenc, G.6
Coban, N.7
Can, G.8
Erginel-Unaltuna, N.9
-
48
-
-
0035200547
-
Genetic infl uences on lipid metabolism trait variability within the Stanislas Cohort
-
Pallaud, C., R. Gueguen, C. Sass, M. Grow, S. Cheng, G. Siest, and S. Visvikis . 2001 . Genetic infl uences on lipid metabolism trait variability within the Stanislas Cohort. J. Lipid Res. 42 : 1879-1890 .
-
(2001)
J. Lipid Res
, vol.42
, pp. 1879-1890
-
-
Pallaud, C.1
Gueguen, R.2
Sass, C.3
Grow, M.4
Cheng, S.5
Siest, G.6
Visvikis, S.7
-
49
-
-
40949149395
-
Polymorphisms associated with cholesterol and risk of cardiovascular events
-
Kathiresan, S., O. Melander, D. Anevski, C. Guiducci, N. P. Burtt, C. Roos, J. N. Hirschhorn, G. Berglund, B. Hedblad, L. Groop, et al . 2008 . Polymorphisms associated with cholesterol and risk of cardiovascular events. N. Engl. J. Med. 358 : 1240-1249 .
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 1240-1249
-
-
Kathiresan, S.1
Melander, O.2
Anevski, D.3
Guiducci, C.4
Burtt, N.P.5
Roos, C.6
Hirschhorn, J.N.7
Berglund, G.8
Hedblad, B.9
Groop, L.10
-
50
-
-
0031470430
-
Common variation in the lipoprotein lipase gene: Effects on plasma lipids and risk of atherosclerosis
-
Fisher, R. M., S. E. Humphries, and P. J. Talmud . 1997 . Common variation in the lipoprotein lipase gene: effects on plasma lipids and risk of atherosclerosis. Atherosclerosis . 135 : 145-159 .
-
(1997)
Atherosclerosis
, vol.135
, pp. 145-159
-
-
Fisher, R.M.1
Humphries, S.E.2
Talmud, P.J.3
-
51
-
-
0035159207
-
Physical activity modulates the combined effect of a common variant of the lipoprotein lipase gene and smoking on serumtriglyceride levels and high-density lipoprotein cholesterol in men
-
Senti, M., R. Elosua, M. Tomas, J. Sala, R. Masia, J. M. Ordovas, H. Shen, and J. Marrugat . 2001 . Physical activity modulates the combined effect of a common variant of the lipoprotein lipase gene and smoking on serumtriglyceride levels and high-density lipoprotein cholesterol in men. Hum. Genet. 109 : 385-392 .
-
(2001)
Hum. Genet
, vol.109
, pp. 385-392
-
-
Senti, M.1
Elosua, R.2
Tomas, M.3
Sala, J.4
Masia, R.5
Ordovas, J.M.6
Shen, H.7
Marrugat, J.8
-
52
-
-
0033843041
-
Lipoprotein lipase gene polymorphism, cholesterol subfractions and myocardial infarction in large samples of the general population
-
Holmer, S. R., C. Hengstenberg, B. Mayer, A. Döring, H. Löwel, S. Engel, H. W. Hense, M. Wolf, G. Klein, G. A. Riegger, et al . 2000 . Lipoprotein lipase gene polymorphism, cholesterol subfractions and myocardial infarction in large samples of the general population. Cardiovasc. Res. 47 : 806-812 .
-
(2000)
Cardiovasc. Res
, vol.47
, pp. 806-812
-
-
Holmer, S.R.1
Hengstenberg, C.2
Mayer, B.3
Döring, A.4
Löwel, H.5
Engel, S.6
Hense, H.W.7
Wolf, M.8
Klein, G.9
Riegger, G.A.10
-
53
-
-
0036208675
-
Associations of LPL and APOC3 gene polymorphisms on plasma lipids in a Mediterranean population: Interaction with tobacco smoking and the APOE locus
-
Corella, D., M. Guillen, C. Saiz, O. Portoles, A. Sabater, J. Folch, and J. M. Ordovas . 2002 . Associations of LPL and APOC3 gene polymorphisms on plasma lipids in a Mediterranean population: interaction with tobacco smoking and the APOE locus. J. Lipid Res. 43 : 416-427 .
-
(2002)
J. Lipid Res
, vol.43
, pp. 416-427
-
-
Corella, D.1
Guillen, M.2
Saiz, C.3
Portoles, O.4
Sabater, A.5
Folch, J.6
Ordovas, J.M.7
-
54
-
-
0034907585
-
Genetic variation at the lipoprotein lipase locus and plasma lipoprotein and insulin levels in the Quebec Family Study
-
Ukkola, O., C. Garenc, L. Perusse, J. Bergeron, J. P. Despres, D. C. Rao, and C. Bouchard . 2001 . Genetic variation at the lipoprotein lipase locus and plasma lipoprotein and insulin levels in the Quebec Family Study. Atherosclerosis . 158 : 199-206 .
-
(2001)
Atherosclerosis
, vol.158
, pp. 199-206
-
-
Ukkola, O.1
Garenc, C.2
Perusse, L.3
Bergeron, J.4
Despres, J.P.5
Rao, D.C.6
Bouchard, C.7
-
55
-
-
57149114180
-
Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions
-
Heid, I. M., E. Boes, M. Müller, B. Kollerits, C. Lamina, S. Coassin, C. Gieger, A. Döring, N. Klopp, R. Frikke-Schmidt, et al . 2008 . Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions. Circ Cardiovasc Genet . 1 : 10-20 .
-
(2008)
Circ Cardiovasc Genet
, vol.1
, pp. 10-20
-
-
Heid, I.M.1
Boes, E.2
Müller, M.3
Kollerits, B.4
Lamina, C.5
Coassin, S.6
Gieger, C.7
Döring, A.8
Klopp, N.9
Frikke-Schmidt, R.10
-
56
-
-
80051499915
-
Rarevariant association testing for sequencing data with the sequence kernel association test
-
Wu, M. C., S. Lee, T. Cai, Y. Li, M. Boehnke, and X. Lin . 2011 . Rarevariant association testing for sequencing data with the sequence kernel association test. Am. J. Hum. Genet. 89 : 82-93 .
-
(2011)
Am. J. Hum. Genet
, vol.89
, pp. 82-93
-
-
Wu, M.C.1
Lee, S.2
Cai, T.3
Li, Y.4
Boehnke, M.5
Lin, X.6
-
57
-
-
79151485129
-
Rare variants in the lipoprotein lipase (LPL) gene are common in hypertriglyceridemia but rare in Type III hyperlipidemia
-
Evans, D., J. Arzer, J. Aberle, and F. U. Beil. 2011 . Rare variants in the lipoprotein lipase (LPL) gene are common in hypertriglyceridemia but rare in Type III hyperlipidemia. Atherosclerosis . 214 : 386-390 .
-
(2011)
Atherosclerosis
, vol.214
, pp. 386-390
-
-
Evans, D.1
Arzer, J.2
Aberle, J.3
Beil, F.U.4
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