Excess of rare variants in non-genome-wide association study candidate genes in patients with hypertriglyceridemia

Circulation: Cardiovascular Genetics

Volumn 5, Issue 1, 2012, Pages 66-72

  Johansen, Christopher T ^a   Wang, Jian ^a   McIntyre, Adam D ^a   Martins, Rebecca A ^a   Ban, Matthew R ^a   Lanktree, Matthew B ^a   Huff, Murray W ^a,b   Péterfy, Miklós ^d   Mehrabian, Margarete ^d   Lusis, Aldons J ^d   Kathiresan, Sekar ^e,f   Anand, Sonia S ^g   Yusuf, Salim ^g   Lee, Ann Hwee ^h   Glimcher, Laurie H ^c,h   Cao, Henian ^a   Hegele, Robert A ^a,b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b WESTERN UNIVERSITY   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^g MCMASTER UNIVERSITY   (Canada)

^h HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Apolipoproteins; Cardiovascular diseases; Genetics; Hyperlipoproteinemia; Lipoproteins

Indexed keywords

APOC2 PROTEIN; CREB3L3 PROTEIN; GPIHBP1 PROTEIN; LMF1 PROTEIN; PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ZHX3 PROTEIN;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; HUMAN; HYPERTRIGLYCERIDEMIA; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGED; APOLIPOPROTEIN C-II; CARRIER PROTEINS; COHORT STUDIES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HETEROZYGOTE; HOMEODOMAIN PROTEINS; HUMANS; HYPERTRIGLYCERIDEMIA; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; ODDS RATIO; REPRESSOR PROTEINS; SEQUENCE ANALYSIS, DNA;

EID: 84860856675     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.960864     Document Type: Article

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