메뉴 건너뛰기




Volumn 55, Issue 1, 2014, Pages 128-137

Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin resistance

Author keywords

Apolipoprotein B 100; Apolipoprotein B 48; Cholesterol; Fatty acids; Intestine; Kinetic

Indexed keywords

APOLIPOPROTEIN B; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; INSULIN; LEUCINE; LIPOPROTEIN; MESSENGER RNA; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; TRIGLYCERIDE RICH LIPOPROTEIN; UNCLASSIFIED DRUG;

EID: 84891349027     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M040071     Document Type: Article
Times cited : (25)

References (43)
  • 1
    • 0033860359 scopus 로고    scopus 로고
    • Insulin resistance and cardiovascular disease
    • Ginsberg , H. N. 2000 . Insulin resistance and cardiovascular disease. J. Clin. Invest. 106 : 453-458 .
    • (2000) J. Clin. Invest. , vol.106 , pp. 453-458
    • Ginsberg, H.N.1
  • 2
    • 33745024354 scopus 로고    scopus 로고
    • Hyperinsulinemia is associated with increased production rate of intestinal apolipoprotein B-48- containing lipoproteins in humans
    • Duez , H. , B. Lamarche , K. D. Uffelman , R. Valero , J. S. Cohn , and G. F. Lewis . 2006 . Hyperinsulinemia is associated with increased production rate of intestinal apolipoprotein B-48- containing lipoproteins in humans. Arterioscler. Thromb. Vasc. Biol. 26 : 1357-1363 .
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 1357-1363
    • Duez, H.1    Lamarche, B.2    Uffelman, K.D.3    Valero, R.4    Cohn, J.S.5    Lewis, G.F.6
  • 3
    • 43249122976 scopus 로고    scopus 로고
    • Both intestinal and hepatic lipoprotein production are stimulated by an acute elevation of plasma free fatty acids in humans
    • Duez , H. , B. Lamarche , R. Valero , M. Pavlic , S. Proctor , C. Xiao , L. Szeto , B. W. Patterson , and G. F. Lewis . 2008 . Both intestinal and hepatic lipoprotein production are stimulated by an acute elevation of plasma free fatty acids in humans. Circulation . 117 : 2369-2376 .
    • (2008) Circulation , vol.117 , pp. 2369-2376
    • Duez, H.1    Lamarche, B.2    Valero, R.3    Pavlic, M.4    Proctor, S.5    Xiao, C.6    Szeto, L.7    Patterson, B.W.8    Lewis, G.F.9
  • 4
    • 0033858450 scopus 로고    scopus 로고
    • Metabolic abnormalities of apolipoprotein B-containing lipoproteins in non-insulin-dependent diabetes: A stable isotope kinetic study
    • Duvillard , L. , F. Pont , E. Florentin , C. Galland-Jos , P. Gambert , and B. Verges . 2000 . Metabolic abnormalities of apolipoprotein B-containing lipoproteins in non-insulin-dependent diabetes: a stable isotope kinetic study. Eur. J. Clin. Invest. 30 : 685-694 .
    • (2000) Eur. J. Clin. Invest. , vol.30 , pp. 685-694
    • Duvillard, L.1    Pont, F.2    Florentin, E.3    Galland-Jos, C.4    Gambert, P.5    Verges, B.6
  • 5
    • 0023123303 scopus 로고
    • Very low density lipoprotein metabolism in diabetes mellitus
    • Ginsberg , H. N. 1987 . Very low density lipoprotein metabolism in diabetes mellitus. Diabetes Metab. Rev. 3 : 571-589 .
    • (1987) Diabetes Metab. Rev. , vol.3 , pp. 571-589
    • Ginsberg, H.N.1
  • 6
    • 34548155292 scopus 로고    scopus 로고
    • Evidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes
    • Hogue , J. C. , B. Lamarche , A. J. Tremblay , J. Bergeron , C. Gagné , and P. Couture . 2007 . Evidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes. J. Lipid Res. 48 : 1336-1342 .
    • (2007) J. Lipid Res. , vol.48 , pp. 1336-1342
    • Hogue, J.C.1    Lamarche, B.2    Tremblay, A.J.3    Bergeron, J.4    Gagné, C.5    Couture, P.6
  • 7
    • 0035177104 scopus 로고    scopus 로고
    • Remnant-like particle (RLP) cholesterol is an independent cardiovascular disease risk factor in women: Results from the Framingham Heart Study
    • McNamara , J. R. , P. K. Shah , K. Nakajima , L. A. Cupples , P. W. Wilson , J. M. Ordovas , and E. J. Schaefer . 2001 . Remnant-like particle (RLP) cholesterol is an independent cardiovascular disease risk factor in women: results from the Framingham Heart Study. Atherosclerosis . 154 : 229-236 .
    • (2001) Atherosclerosis , vol.154 , pp. 229-236
    • McNamara, J.R.1    Shah, P.K.2    Nakajima, K.3    Cupples, L.A.4    Wilson, P.W.5    Ordovas, J.M.6    Schaefer, E.J.7
  • 8
    • 0031440816 scopus 로고    scopus 로고
    • Postprandial elevation of ApoB-48-containing triglyceriderich particles and retinyl esters in normolipemic males who smoke
    • Mero , N. , M. Syvanne , B. Eliasson , U. Smith , and M. R. Taskinen . 1997 . Postprandial elevation of ApoB-48-containing triglyceriderich particles and retinyl esters in normolipemic males who smoke. Arterioscler. Thromb. Vasc. Biol. 17 : 2096-2102 .
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 2096-2102
    • Mero, N.1    Syvanne, M.2    Eliasson, B.3    Smith, U.4    Taskinen, M.R.5
  • 10
    • 43249119219 scopus 로고    scopus 로고
    • Intestinal lipoprotein overproduction in insulin-resistant states
    • Adeli , K. , and G. F. Lewis . 2008 . Intestinal lipoprotein overproduction in insulin-resistant states. Curr. Opin. Lipidol. 19 : 221-228 .
    • (2008) Curr. Opin. Lipidol. , vol.19 , pp. 221-228
    • Adeli, K.1    Lewis, G.F.2
  • 11
    • 33745802004 scopus 로고    scopus 로고
    • Overproduction of intestinal lipoprotein containing apolipoprotein B-48 in Psammomys obesus: Impact of dietary n-3 fatty acids
    • Levy , E. , S. Spahis , E. Ziv , A. Marette , M. Elchebly , M. Lambert , and E. Delvin . 2006 . Overproduction of intestinal lipoprotein containing apolipoprotein B-48 in Psammomys obesus: impact of dietary n-3 fatty acids. Diabetologia . 49 : 1937-1945 .
    • (2006) Diabetologia , vol.49 , pp. 1937-1945
    • Levy, E.1    Spahis, S.2    Ziv, E.3    Marette, A.4    Elchebly, M.5    Lambert, M.6    Delvin, E.7
  • 12
    • 33846829068 scopus 로고    scopus 로고
    • Genes that affect cholesterol synthesis, cholesterol absorption, and chylomicron assembly: The relationship between the liver and intestine in control and streptozotosin diabetic rats
    • Lally , S. , D. Owens , and G. H. Tomkin . 2007 . Genes that affect cholesterol synthesis, cholesterol absorption, and chylomicron assembly: the relationship between the liver and intestine in control and streptozotosin diabetic rats. Metabolism . 56 : 430-438 .
    • (2007) Metabolism , vol.56 , pp. 430-438
    • Lally, S.1    Owens, D.2    Tomkin, G.H.3
  • 13
    • 34447320754 scopus 로고    scopus 로고
    • The different effect of pioglitazone as compared to insulin on expression of hepatic and intestinal genes regulating post-prandial lipoproteins in diabetes
    • Lally , S. , D. Owens , and G. H. Tomkin . 2007 . The different effect of pioglitazone as compared to insulin on expression of hepatic and intestinal genes regulating post-prandial lipoproteins in diabetes. Atherosclerosis . 193 : 343-351 .
    • (2007) Atherosclerosis , vol.193 , pp. 343-351
    • Lally, S.1    Owens, D.2    Tomkin, G.H.3
  • 15
    • 33745026603 scopus 로고
    • The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
    • Havel , R. J. , H. Eder , and J. Bragdon . 1955 . The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34 : 1345-1353 .
    • (1955) J. Clin. Invest. , vol.34 , pp. 1345-1353
    • Havel, R.J.1    Eder, H.2    Bragdon, J.3
  • 16
    • 0018191438 scopus 로고
    • Multilaboratory comparison of three heparin-Mn2+ precipitation procedures for estimating cholesterol in high-density lipoprotein
    • Albers , J. J. , G. R. Warnick , D. Wiebe , P. King , P. Steiner , L. Smith , C. Breckenridge , A. Chow , K. Kuba , S. Weidman , et al . 1978 . Multilaboratory comparison of three heparin-Mn2+ precipitation procedures for estimating cholesterol in high-density lipoprotein. Clin. Chem. 24 : 853-856 .
    • (1978) Clin. Chem. , vol.24 , pp. 853-856
    • Albers, J.J.1    Warnick, G.R.2    Wiebe, D.3    King, P.4    Steiner, P.5    Smith, L.6    Breckenridge, C.7    Chow, A.8    Kuba, K.9    Weidman, S.10
  • 17
    • 0142010508 scopus 로고    scopus 로고
    • Impact of simvastatin, niacin, and/or antioxidants on cholesterol metabolism in CAD patients with low HDL
    • Matthan , N. R. , A. Giovanni , E. J. Schaefer , B. G. Brown , and A. H. Lichtenstein . 2003 . Impact of simvastatin, niacin, and/or antioxidants on cholesterol metabolism in CAD patients with low HDL. J. Lipid Res. 44 : 800-806 .
    • (2003) J. Lipid Res. , vol.44 , pp. 800-806
    • Matthan, N.R.1    Giovanni, A.2    Schaefer, E.J.3    Brown, B.G.4    Lichtenstein, A.H.5
  • 18
    • 0015146643 scopus 로고
    • Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays
    • Desbuquois , B. , and G. D. Aurbach . 1971 . Use of polyethylene glycol to separate free and antibody-bound peptide hormones in radioimmunoassays. J. Clin. Endocrinol. Metab. 33 : 732-738 .
    • (1971) J. Clin. Endocrinol. Metab. , vol.33 , pp. 732-738
    • Desbuquois, B.1    Aurbach, G.D.2
  • 19
    • 0015058419 scopus 로고
    • Determination of plasma glucose by hexokinase-glucose-6-phosphate dehydrogenase method
    • Richterich , R. , and H. Dauwalder . 1971 . Determination of plasma glucose by hexokinase-glucose-6-phosphate dehydrogenase method. Schweiz. Med. Wochenschr. 101 : 615-618 .
    • (1971) Schweiz. Med. Wochenschr. , vol.101 , pp. 615-618
    • Richterich, R.1    Dauwalder, H.2
  • 20
    • 0016830667 scopus 로고
    • Radioimmunological determination of human C-peptide in serum
    • Heding , L. G. 1975 . Radioimmunological determination of human C-peptide in serum. Diabetologia . 11 : 541-548 .
    • (1975) Diabetologia , vol.11 , pp. 541-548
    • Heding, L.G.1
  • 21
    • 0037902984 scopus 로고    scopus 로고
    • Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
    • Vilsboll , T. , T. Krarup , J. Sonne , S. Madsbad , A. Volund , A. G. Juul , and J. J. Holst . 2003 . Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 88 : 2706-2713 .
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 2706-2713
    • Vilsboll, T.1    Krarup, T.2    Sonne, J.3    Madsbad, S.4    Volund, A.5    Juul, A.G.6    Holst, J.J.7
  • 22
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews , D. R. , J. P. Hosker , A. S. Rudenski , B. A. Naylor , D. F. Treacher , and R. C. Turner . 1985 . Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia . 28 : 412-419 .
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 23
    • 0028959538 scopus 로고
    • Quantifi cation of apolipoproteins B-100, B-48, and e in human triglyceride-rich lipoproteins
    • Kotite , L. , N. Bergeron , and R. J. Havel . 1995 . Quantifi cation of apolipoproteins B-100, B-48, and E in human triglyceride-rich lipoproteins. J. Lipid Res. 36 : 890-900 .
    • (1995) J. Lipid Res. , vol.36 , pp. 890-900
    • Kotite, L.1    Bergeron, N.2    Havel, R.J.3
  • 25
    • 0036186714 scopus 로고    scopus 로고
    • Oxazolinone derivative of leucine for GC-MS: A sensitive and robust method for stable isotope kinetic studies of lipoproteins
    • Dwyer , K. P. , P. H. Barrett , D. Chan , J. I. Foo , G. F. Watts , and K. D. Croft . 2002 . Oxazolinone derivative of leucine for GC-MS: a sensitive and robust method for stable isotope kinetic studies of lipoproteins. J. Lipid Res. 43 : 344-349 .
    • (2002) J. Lipid Res. , vol.43 , pp. 344-349
    • Dwyer, K.P.1    Barrett, P.H.2    Chan, D.3    Foo, J.I.4    Watts, G.F.5    Croft, K.D.6
  • 26
    • 0023511517 scopus 로고
    • Models to interpret kinetic data in stable isotope tracer studies
    • Cobelli , C. , G. Toffolo , D. M. Bier , and R. Nosadini . 1987 . Models to interpret kinetic data in stable isotope tracer studies. Am. J. Physiol. 253 : E551-E564 .
    • (1987) Am. J. Physiol. , vol.253
    • Cobelli, C.1    Toffolo, G.2    Bier, D.M.3    Nosadini, R.4
  • 27
    • 67650552637 scopus 로고    scopus 로고
    • Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia
    • Tremblay , A. J. , B. Lamarche , J. C. Hogue , and P. Couture . 2009 . Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia. J. Lipid Res. 50 : 1463-1471 .
    • (2009) J. Lipid Res. , vol.50 , pp. 1463-1471
    • Tremblay, A.J.1    Lamarche, B.2    Hogue, J.C.3    Couture, P.4
  • 28
    • 84879426830 scopus 로고    scopus 로고
    • Short-term, high-fat diet increases the expression of key intestinal genes involved in lipoprotein metabolism in healthy men
    • Tremblay , A. J. , B. Lamarche , V. Guay , A. Charest , V. Lemelin , and P. Couture . 2013 . Short-term, high-fat diet increases the expression of key intestinal genes involved in lipoprotein metabolism in healthy men. Am. J. Clin. Nutr. 98 : 32-41 .
    • (2013) Am. J. Clin. Nutr. , vol.98 , pp. 32-41
    • Tremblay, A.J.1    Lamarche, B.2    Guay, V.3    Charest, A.4    Lemelin, V.5    Couture, P.6
  • 30
    • 0037199988 scopus 로고    scopus 로고
    • Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction
    • Haidari , M. , N. Leung , F. Mahbub , K. D. Uffelman , R. Kohen- Avramoglu , G. F. Lewis , and K. Adeli . 2002 . Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction. J. Biol. Chem. 277 : 31646-31655 .
    • (2002) J. Biol. Chem. , vol.277 , pp. 31646-31655
    • Haidari, M.1    Leung, N.2    Mahbub, F.3    Uffelman, K.D.4    Kohen- Avramoglu, R.5    Lewis, G.F.6    Adeli, K.7
  • 31
    • 0346492596 scopus 로고    scopus 로고
    • Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly
    • Zoltowska , M. , E. Ziv , E. Delvin , M. Lambert , E. Seidman , and E. Levy . 2004 . Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly. Arterioscler. Thromb. Vasc. Biol. 24 : 118-123 .
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 118-123
    • Zoltowska, M.1    Ziv, E.2    Delvin, E.3    Lambert, M.4    Seidman, E.5    Levy, E.6
  • 32
    • 0141755321 scopus 로고    scopus 로고
    • Cellular aspects of intestinal lipoprotein assembly in Psammomys obesus: A model of insulin resistance and type 2 diabetes
    • Zoltowska , M. , E. Ziv , E. Delvin , D. Sinnett , R. Kalman , C. Garofalo , E. Seidman , and E. Levy . 2003 . Cellular aspects of intestinal lipoprotein assembly in Psammomys obesus: a model of insulin resistance and type 2 diabetes. Diabetes . 52 : 2539-2545 .
    • (2003) Diabetes , vol.52 , pp. 2539-2545
    • Zoltowska, M.1    Ziv, E.2    Delvin, E.3    Sinnett, D.4    Kalman, R.5    Garofalo, C.6    Seidman, E.7    Levy, E.8
  • 33
    • 33846040734 scopus 로고    scopus 로고
    • Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: Increased atherogenicity for the metabolic syndrome
    • Vine , D. F. , R. Takechi , J. C. Russell , and S. D. Proctor . 2007 . Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: increased atherogenicity for the metabolic syndrome. Atherosclerosis . 190 : 282-290 .
    • (2007) Atherosclerosis , vol.190 , pp. 282-290
    • Vine, D.F.1    Takechi, R.2    Russell, J.C.3    Proctor, S.D.4
  • 36
    • 84876296329 scopus 로고    scopus 로고
    • Alteration in intestinal insulin signaling in obese subjects and their effect on lipid and lipoprotein metabolism
    • Veilleux , A. , E. Grenier , A. Carpentier , A. Richard , and E. Levy . 2012 . Alteration in intestinal insulin signaling in obese subjects and their effect on lipid and lipoprotein metabolism. Diabetes . 61 (Suppl. 1): A15 .
    • (2012) Diabetes , vol.61 SUPPL. 1
    • Veilleux, A.1    Grenier, E.2    Carpentier, A.3    Richard, A.4    Levy, E.5
  • 37
    • 33744812746 scopus 로고    scopus 로고
    • Intestinal microsomal triglyceride transfer protein in type 2 diabetic and nondiabetic subjects: The relationship to triglyceride-rich postprandial lipoprotein composition
    • Phillips , C. , K. Mullan , D. Owens , and G. H. Tomkin . 2006 . Intestinal microsomal triglyceride transfer protein in type 2 diabetic and nondiabetic subjects: the relationship to triglyceride-rich postprandial lipoprotein composition. Atherosclerosis . 187 : 57-64 .
    • (2006) Atherosclerosis , vol.187 , pp. 57-64
    • Phillips, C.1    Mullan, K.2    Owens, D.3    Tomkin, G.H.4
  • 38
    • 0027945062 scopus 로고
    • Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specifi c expression and response to metabolic regulators
    • Hagan , D. L. , B. Kienzle , H. Jamil , and N. Hariharan . 1994 . Transcriptional regulation of human and hamster microsomal triglyceride transfer protein genes. Cell type-specifi c expression and response to metabolic regulators. J. Biol. Chem. 269 : 28737-28744 .
    • (1994) J. Biol. Chem. , vol.269 , pp. 28737-28744
    • Hagan, D.L.1    Kienzle, B.2    Jamil, H.3    Hariharan, N.4
  • 39
    • 0029047046 scopus 로고
    • Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: Insulin negatively regulates MTP gene expression
    • Lin , M. C. , D. Gordon , and J. R. Wetterau . 1995 . Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression. J. Lipid Res. 36 : 1073-1081 .
    • (1995) J. Lipid Res. , vol.36 , pp. 1073-1081
    • Lin, M.C.1    Gordon, D.2    Wetterau, J.R.3
  • 40
    • 77950363795 scopus 로고    scopus 로고
    • Insulin acutely inhibits intestinal lipoprotein secretion in humans in part by suppressing plasma free fatty acids
    • Pavlic , M. , C. Xiao , L. Szeto , B. W. Patterson , and G. F. Lewis . 2010 . Insulin acutely inhibits intestinal lipoprotein secretion in humans in part by suppressing plasma free fatty acids. Diabetes . 59 : 580-587 .
    • (2010) Diabetes , vol.59 , pp. 580-587
    • Pavlic, M.1    Xiao, C.2    Szeto, L.3    Patterson, B.W.4    Lewis, G.F.5
  • 41
    • 38149136598 scopus 로고    scopus 로고
    • Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents
    • Ota , T. , C. Gayet , and H. N. Ginsberg . 2008 . Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents. J. Clin. Invest. 118 : 316-332 .
    • (2008) J. Clin. Invest. , vol.118 , pp. 316-332
    • Ota, T.1    Gayet, C.2    Ginsberg, H.N.3
  • 42
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membranebound transcription factor
    • Brown , M. S. , and J. L. Goldstein . 1997 . The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membranebound transcription factor. Cell . 89 : 331-340 .
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 43
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton , J. D. , J. L. Goldstein , and M. S. Brown . 2002 . SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109 : 1125-1131
    • (2002) J. Clin. Invest. , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.