Serum concentrations of polychlorinated biphenyls (PCBs) in participants of the Anniston Community Health Survey

Science of the Total Environment

Volumn 473-474, Issue , 2014, Pages 286-297

  Pavuk, M ^a   Olson, J R ^b   Sjodin A ^c   Wolff, P ^d   Turner, W E ^c   Shelton, C ^e   Dutton, N D ^a   Bartell, S ^f   Carter, S ^l   Carpenter, D O ^g   Cash, J ^d   Percy, A ^d   Frumkin, H ^h   Lavender, M ⁱ   Moysich, K ^j   Rosenbaum, P ^k   Silverstone, A ^k   Weinstock, R ^k  

^a AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e JACKSONVILLE STATE UNIVERSITY   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g STATE UNIVERSITY OF NEW YORK   (United States)

^h UNIVERSITY OF WASHINGTON   (United States)

ⁱ Center for Domestic Preparedness   (United States)

^j ROSWELL PARK CANCER INSTITUTE   (United States)

^k SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^l University at Buffalo ^*

more..

Author keywords

Anniston; Exposure; Polychlorinated biphenyls

Indexed keywords

BODY FLUIDS; POLYCHLORINATED BIPHENYLS; PRINCIPAL COMPONENT ANALYSIS; PUBLIC HEALTH; SURVEYS;

ANNISTON; EXPOSURE; MEDIAN CONCENTRATION; POLYCHLORINATED BIPHENYL (PCBS); POLYCHLORINATED BIPHENYL CONGENER; QUESTIONNAIRE INFORMATION; RELATIVE CONTRIBUTION; SUBSTITUTION PATTERNS;

ORGANIC POLLUTANTS;

DECACHLORINATED POLYCHLORINATED BIPHENYL DERIVATIVE; HEPTACHLOROBIPHENYL DERIVATIVE; OCTACHLORINATED POLYCHLORINATED BIPHENYL DERIVATIVE; PENTACHLOROBIPHENYL DERIVATIVE; POLYCHLORINATED BIPHENYL DERIVATIVE; TETRACHLORINATED POLYCHLORINATED BIPHENYL DERIVATIVE; TRICHLORINATED POLYCHLORINATED BIPHENYL DERIVATIVE; UNCLASSIFIED DRUG;

AFRICAN AMERICAN; CONCENTRATION (COMPOSITION); ENVIRONMENTAL RISK; HEALTH IMPACT; HEALTH RISK; HEALTH SURVEY; PCB; POLLUTION EXPOSURE; PRINCIPAL COMPONENT ANALYSIS; SERUM;

ADULT; AFRICAN AMERICAN; AGE DISTRIBUTION; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD LEVEL; CAUCASIAN; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; ETHNIC DIFFERENCE; FEMALE; GEOGRAPHIC DISTRIBUTION; HEALTH SURVEY; HUMAN; LIMIT OF DETECTION; MALE; OCCUPATION; PRIORITY JOURNAL; RESIDENTIAL AREA; UNITED STATES;

ALABAMA; ANNISTON; UNITED STATES;

ACHS; AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY; ANNISTON; ANNISTON COMMUNITY HEALTH SURVEY; ATSDR; CDC; CENTERS FOR DISEASE CONTROL AND PREVENTION; CI; CONFIDENCE INTERVAL; EPA; EXPOSURE; GEOMETRIC MEAN; GM; LIMIT OF DETECTION; LOD; NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY; NHANES; PCBS; POLYCHLORINATED BIPHENYLS; U.S. ENVIRONMENTAL PROTECTION AGENCY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALABAMA; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; HEALTH SURVEYS; HUMANS; MALE; MIDDLE AGED; POLYCHLORINATED BIPHENYLS; PRINCIPAL COMPONENT ANALYSIS; UNITED STATES; YOUNG ADULT;

EID: 84891291228     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2013.12.041     Document Type: Article

References (76)

1. 21 Code of Federal Regulations 109.30 Tolerances for polychlorinated biphenyls (PCB's) 2012, [1 April].
2. ADPH (Alabama Department of Public Health) Health consultation: Monsanto Company, Anniston, Calhoun County, Alabama. CERCLIS No. ALD004019048 1995.
3. ADPH (Alabama Department of Public Health) Health consultation: Cobbtown/Sweet Valley Community PCB exposure investigation 1996, [Anniston, Calhoun County, Alabama].
4. ADPH (Alabama Department of Public Health) Alabama fish consumption advisory guidelines 2002-2011 [Accessed 01/27/2012]. http://adph.org/tox/index.asp?id=1360.
5. ASTM (American Society for Testing and Materials) Committee on standards designation, D4210-89: 2-7 1989, ASTM, Philadelphia.
6. ATSDR (Agency for Toxic Substances and Disease Registry) Toxicological profile for polychlorinated biphenyls (PCBs) 2000, U.S. Department of Health and Human Services, Atlanta.
7. ATSDR (Agency for Toxic Substances, Disease Registry) Health consultation: evaluation of soil, blood & air data from Anniston, Alabama. Monsanto Company, Anniston, Calhoun County, Alabama. CERCLIS No. ALD004019048 2000, U.S. Department of Health and Human Services, Atlanta.
8. ATSDR (Agency for Toxic Substances, Disease Registry) Health consultation: exposure investigation report. Monsanto Company, Anniston, Calhoun County, Alabama. CERCLIS No. ALD004019048 2000, U.S. Department of Health and Human Services, Atlanta.
9. ATSDR (Agency for Toxic Substances, Disease Registry) Updated assessment of PCB exposures in Anniston, AL; Anniston PCB site, Anniston, Calhoun County, Alabama. EPA Facility ID: ALD004019048 2006, U.S. Department of Health and Human Services, Atlanta.
10. Bernert J.T., Turner W.E., Patterson D.G., Needham L.L. Calculation of serum "total lipid" concentrations for the adjustment of persistent organohalogen toxicant measurements in human samples. Chemosphere 2007, 68:824-831.
11. Brown J.F., Lawton R.W. Factors controlling the distribution and levels of PCBs after occupational exposure. PCBs 2001, 103-109. University Press of Kentucky, Lexington, KY. L.W. Robertson, L.G. Hansen (Eds.).
12. Carpenter D.O., Morris D.L., Legator M. Initial attempts to profile health effects with types of exposures in Anniston, Alabama. Fresenius Environ Bull 2003, 12:191-195.
13. Chemical Industry Archives, Environmental Working Group Trial Transcript, Owens v. Monsanto CV-96-J-440-E, (N.D. Alabama April 5, 2001), pg. 551, line 1; a memo from E.S. Tucker to W.B. Papageorge, December 21, 1970 (both Monsanto, PCB results for hog's liver and fat samples) [Accessed: February 15, 2013]. http://www.chemicalindustryarchives.org/dirtysecrets/annistonindepth/wildlife.asp.
14. Choi A.L., Levy J.I., Dockery D.W., Ryan L.M., Tolbert P.E., Altshul L.M., et al. Does living near a Superfund site contribute to higher polychlorinated biphenyl (PCB) exposure?. Environ Health Perspect 2006, 114(7):1092-1098.
15. Codru N., Schymura M.J., Negoita S. Diabetes in relation to serum levels of polychlorinated biphenyls and chlorinated pesticides in adult Native Americans. Environ Health Perspect 2007, 115(10):1442-1447.
16. De Roos A.M., Hartge P., Lubin J.H., Colt J.S., Davis S., Cerhan J.R., et al. Persistent organochlorine chemicals in plasma and risk of non-Hodgkin's lymphoma. Cancer Res 2005, 65(23):11214-11226.
17. DeCaprio A.P., Johnson G.W., Tarbell A.M., Carpenter D.O., Chiarenzelli J.R., Morse G.S., et al. Polychlorinated biphenyl (PCB) exposure assessment by multivariate statistical analysis of serum congener profiles in an adult Native American population. Environ Res 2005, 98(3):284-302.
18. Durfee R.L. Production and usage of PCBs in the United States. Proceedings of the National Conference on Polychlorinated Biphenyls, Chicago, 1975. EPA-560/6-75-004 1976, 103-107. U.S. Environmental Protection Agency, Washington, DC.
19. EPA (U.S.Environmental Protection Agency) PCBs in the United States: industrial use and environmental distribution. NTIS PB252012 1976, U.S. Environmental Protection Agency, Office of Toxic Substances, Washington, DC.
20. Everett C.J., Mainous A.G., Frithsen I.L., Player M.S., Matheson E.M. Association of polychlorinated biphenyls with hypertension in the 1999-2002 National Health and Nutrition Examination Survey. Environ Res 2008, 108(1):94-97.
21. Fischbein A., Wolff M.S., Lilis R., Thornton J., Selikoff I.J. Clinical findings among PCB-exposed capacitor manufacturing workers. Ann N Y Acad Sci 1979, 320:703-715.
22. Fitzgerald E.F., Belanger E.E., Gomez M.I., Hwang S.A., Jansing R.L., Hicks H.E. Environmental exposures to polychlorinated biphenyls (PCBs) among older residents of upper Hudson River communities. Environ Res 2007, 104:352-360.
23. Fitzgerald E.F., Hwang S.A., Gomez M., Bush B., Yang B.Z., Tarbell A. Environmental and occupational exposures and serum PCB concentrations and patterns among Mohawk men at Akwesasne. J Expo Sci Environ Epidemiol 2007, 17(3):269-278.
24. Fitzgerald E.F., Shrestha S., Gomez M.I., McCaffrey R.J., Zimmerman E.A., Kannan K., et al. Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and neuropsychological status among older adults in New York. Neurotoxicology 2012, 33(1):8-15.
25. Frame G.M., Cochran J.W., Bowadt S.S. Complete PCB congener distributions for 17 Aroclor mixtures determined by 3 HRGC systems optimized for comprehensive, quantitative, congener-specific analysis. J High Resolut Chromatogr 1996, 19(12):657-668.
26. Goncharov A., Bloom M., Pavuk M., Birman I., Carpenter D.O. Blood pressure and hypertension in relation to levels of serum polychlorinated biphenyls in residents of Anniston, Alabama. J Hypertens 2010, 28(10):2053-2060.
27. Goncharov A., Pavuk M., Foushee H.R., Carpenter D.O., for the Anniston Environmental Health Research Consortium Blood pressure in relation to concentrations of PCB congeners and chlorinated pesticides. Environ Health Perspect 2011, 119(3):319-325.
28. Grunwald, M., 2001, January 1. Monsanto Hid Decades Of Pollution But No One Was Ever Told. Washington Post.
29. Ha M.H., Lee D.H., Son H.K., Park S.K., Jacobs D.R. Association between serum concentrations of persistent organic pollutants and prevalence of newly diagnosed hypertension: results from the National Health and Nutrition Examination Survey 1999-2002. J Hum Hypertens 2009, 23:274-286.
30. Hansen L.G. Stepping backward to improve assessment of PCB congener toxicities. Environ Health Perspect 1998, 106(Suppl. 1):171-189.
31. Hansen L.G. The ortho-side of PCBs. Occurrence and disposition 1999, Kluwer Academic Publishers, Boston.
32. Hansen L. Identification of steady state and episodic PCB congeners from multiple pathway exposures. PCBs 2001, 47-56. University Press of Kentucky, Lexington, KY. L.W. Robertson, L.G. Hansen (Eds.).
33. Hansen L.G., DeCaprio A.P., Nisbet I.C.T. PCB congener comparisons reveal exposure histories for residents of Anniston, Alabama, USA. Fresenius Environ Bull 2003, 12(2):181-190.
34. Hardell L., van Bavel B., Lindström G., Carlberg M., Eriksson M., Dreifaldt A.C., et al. Concentrations of polychlorinated biphenyls in blood and the risk for testicular cancer. Int J Androl 2004, 27(5):282-290.
35. Heilmann C., Grandjean P., Weihe P., Nielsen F., Budtz-Jørgensen E. Reduced antibody responses to vaccinations in children exposed to polychlorinated biphenyls. PLoS Med 2006, 3(8):1352-1359.
36. Hermanson M.H., Johnson G.W. Polychlorinated biphenyls in tree bark near a former manufacturing plant in Anniston, Alabama. Chemosphere 2007, 68:191-198.
37. Hermanson M.H., Scholten C.A., Compher K. Variable air temperature response of gas-phase atmospheric polychlorinated biphenyls near a former manufacturing facility. Environ Sci Technol 2003, 37:4038-4042.
38. Hornung R.W., Reed D.R. Estimation of average concentration in the presence of nondetectable values. App Occup Environ Hyg 1990, 5(1):46-51.
39. Hovinga M.E., Sowers M., Humphrey H.E. Historical changes in serum PCB and DDT levels in an environmentally-exposed cohort. Arch Environ Contam Toxicol 1992, 22(4):362-366.
40. Humphrey H.E., Budd M.L. Michigan's fisheater cohorts: a prospective history of exposure. Toxicol Ind Health 1996, 12(3-4):499-505.
41. IARC (International Agency for Research on Cancer) Polychlorinated Dibenzo-para-dioxins and polychlorinated dibenzofurans. IARC Monogr Eval Carcinog Risks Hum 1997, 69.
42. Johnson G.W., Ehrlich R., Full W. Principal component analysis and receptor models in environmental forensics. Introduction to environmental forensics 2002, Academic Press. B.L. Murphy, R.D. Morrison (Eds.).
43. Joliffe I.T. Principal component analysis 2002, Springer. 2nd ed.
44. Kimbrough R.D., Krouskas C.A., Carson M.L., Long T.F., Bevan C., Tardiff R.G. Human uptake of persistent chemicals from contaminated soil: PCDD/Fs and PCBs. Regul Toxicol Pharmacol 2010, 57:43-54.
45. Kreiss K., Zack M.M., Kimbrough R.D., Needham L.L., Smrek A.L., Jones B.T. Association of blood pressure and polychlorinated biphenyl levels. JAMA 1981, 245(24):2505-2509.
46. Laden F., Collman G., Iwamoto K., Alberg A.J., Berkowitz G.S., Freudenheim J.L., Hankinson S.E., Helzlsouer K.J., Holford T.R., Huang H.Y., Moysich K.B., Tessari J.D., Wolff M.S., Zheng T., Hunter D.J. 1,1-Dichloro-2,2-bis(pchlorophenyl)ethylene and polychlorinated biphenyls and breast cancer: combined analysis of five U.S. studies. J. Natl. Cancer Inst 2001, 93(10):768-776.
47. Langer P., Tajtáková M., Guretzki H.J., Kocan A., Petrík J., Chovancová J., et al. High prevalence of anti-glutamic acid decarboxylase (anti-GAD) antibodies in employees at a polychlorinated biphenyl production factory. Arch Environ Health 2002, 57(5):412-415.
48. Langer P., Kočan A., Tajtáková M., Sušienková K., Rádiková Ž., Koška J., et al. Multiple adverse thyroid and metabolic health signs in the population from the area heavily polluted by organochlorine cocktail (PCB, DDE, HCB, dioxin). Thyroid Res 2009, 2(3).
49. Lee D.H., Lee I.K., Jin S.H., Steffes M., Jacobs D.R. Association between serum concentrations of persistent organic pollutants and insulin resistance among nondiabetic adults: results from the National Health and Nutrition Examination Survey 1999-2002. Diabetes Care 2007, 30(3):622-628.
50. Lee D.H., Lind P.M., Jacobs D.R., Salihovic S., van Bavel B., Lind L. Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study. Diabetes Care 2011, 34(8):1778-1784.
51. Löffler G., van Bavel B. Potential pathways and exposure to explain the human body burden of organochlorine compounds: a multivariate statistical analysis of human monitoring in Würzburg, Germany. Chemosphere 2000, 40(9-11):1075-1082.
52. Longnecker M.P., Wolff M.S., Gladen B.C., Brock J.W., Grandjean P., Jacobson J.L., et al. Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment. Environ Health Perspect 2003, 111(1):65-70.
53. Love D. My city was gone: one American town's toxic secret, its angry band of locals, and a $700million day in court 2007, Harper Perennial Publishers.
54. Martín-Jiménez T., Hansen L.G. Toxicokinetic extrapolation of PCB exposure in Anniston, Alabama. PCBs: human and environmental disposition and toxicology 2008, 70-79. University of Illinois Press, Champaign, IL. L.W. Robertson, L.G. Hansen (Eds.).
55. Megson D., O'Sullivan G., Comber S., Worsfold P.J., Lohan M.C., Edwards M.R., et al. Elucidating the structural properties that influence the persistence of PCBs in humans using the National Health and Nutrition Examination Survey (NHANES) dataset. Sci Total Environ 2013, 461-462:99-107.
56. Nisbet I.C., Sarofim A.F. Rates and routes of transport of PCBs in the environment. Environ Health Perspect 1972, 1:21-38.
57. Orloff K.G., Dearwent S., Metcalf S., Kathman S., Turner W. Human exposure to polychlorinated biphenyls in a residential community. Arch Environ Contam Toxicol 2003, 44:125-131.
58. Park H.Y., Hertz-Picciotto I., Petrik J., Palkovicova L., Kocan A., Trnovec T. Prenatal PCB exposure and thymus size at birth in neonates in Eastern Slovakia. Environ Health Perspect 2008, 116(1):104-109.
59. Patterson D.G., Wong L.Y., Turner W.E., Caudill S.P., Dipietro E.S., McClure P.C., et al. Levels in the U.S. population of those persistent organic pollutants (2003-2004) included in the Stockholm Convention or in other Long-Range Transboundary Air Pollution Agreements. Environ Sci Technol 2009, 43(4):1211-1218.
60. Persky V., Turyk M., Anderson H.A., Hanrahan L.P., Falk C., Steenport D.N., et al. The effects of PCB exposure and fish consumption on endogenous hormones. Environ Health Perspect 2001, 109:1275-1283.
61. Rylander L., Rignell-Hydborn A., Hagmar L. A cross-sectional study of the association between persistent organochlorine pollutants and diabetes. Environ Health 2005, 4:28-33.
62. Safe S. Toxicology, structure-function relationship, and human and environmental health impacts of polychlorinated biphenyls: progress and problems. Environ Health Perspect 1993, 100:259-268.
63. Salay E., Garabrant D. Polychlorinated biphenyls and thyroid hormones in adults: a systematic review appraisal of epidemiological studies. Chemosphere 2009, 74(11):1413-1419.
64. Schecter A., Cramer P., Boggess K., Stanley J., Päpke O., Olson J., et al. Intake of dioxins and related compounds from food in the US population. J Toxicol Environ Health A 2001, 63:101-118.
65. Schenker N., Gentleman J.F., Rose D., Hing E., Shimizu I.M. Combining estimates from complementary surveys: a case study using prevalence estimates from national health surveys of households and nursing homes. Public Health Rep 2002, 117(4):393-407.
66. Seegal R.F., Fitzgerald E.F., Hills E.A., Wolff M.S., Haase R.F., Todd A.C., et al. Estimating the half-lives of PCB congeners in former capacitor workers measured over a 28-year interval. J Expo Sci Environ Epidemiol 2011, 21:234-246.
67. Silverstone A.E., Rosenbaum P.F., Weinstock R.S., Bartell S.M., Foushee H.R., Shelton C., et al. Polychlorinated biphenyl (PCB) exposure and diabetes: results from the Anniston Community Health Survey. Environ Health Perspect 2012, 120(5):727-732.
68. Sjödin A., Jones R.S., Lapeza C.R., Focant J.F., McGahee E.E., Patterson D.G. Semiautomated high-throughput extraction and cleanup method for the measurement of polybrominated diphenyl ethers, polybrominated biphenyls, and polychlorinated biphenyls in human serum. Anal Chem 2004, 76:1921-1927.
69. Startin J.R. Dioxins in food. Dioxins and health 1994, 115-137. Plenum Press, New York. A. Schecter (Ed.).
70. Taylor K.W., Novak R.F., Anderson H.A., Birnbaum L.S., Blystone C., Devito M., et al. Evaluation of the association between persistent organic pollutants (POPs) and diabetes in epidemiological studies: a national toxicology program workshop review. Environ Health Perspect 2013, 121(7):774-783.
71. Turyk M.E., Anderson H.A., Persky V.W. Relationships of thyroid hormones with polychlorinated biphenyls, dioxins, furans, and DDE in adults. Environ Health Perspect 2007, 115:1197-1203.
72. Van den Berg M., Birnbaum L.S., Denison M., De Vito M., Farland W., Feeley M., et al. The 2005 World Health Organization reevaluation of human and mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol Sci 2006, 93(2):223-241.
73. Vasiliu O., Cameron L., Gardiner J., Deguire P., Karmaus W. Polybromated biphenyls, polychlorinated biphenyls, body weight, and incidence of adult-onset diabetes mellitus. Epidemiology 2006, 17(4):352-359.
74. Wang S.-L., Su P.-H., Jong S.-B., Guo Y.L., Chou W.-L., Päpke O. In utero exposure to dioxins and polychlorinated biphenyls and its relations to thyroid function and growth hormone in newborns. Environ Health Perspect 2005, 113(11):1645-1650.
75. Warner J., Osuch J.R., Karmaus W., Landgraf J.R., Taffe B., O'Keefe M., et al. Common classification schemes for PCB congeners and the gene expression of CYP17, CYP19, ESR1 and ESR2. Sci Total Environ 2012, 414:81-89.
76. Wolff M.S., Fischbein A., Thornton J., Rice C., Lilis R., Selikoff I.J. Body burden of polychlorinated biphenyls among persons employed in capacitor manufacturing. Int Arch Environ Health 1982, 49:199-208.