A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease

Experimental Neurology

Volumn 252, Issue , 2014, Pages 105-113

  Song, Jung Min ^a   DiBattista, Amanda Marie ^a   Sung, You Me ^e   Ahn, Joo Myung ^a   Turner, R Scott ^a   Yang, Jerry ^c   Pak, Daniel T S ^a   Lee, Hey Kyoung ^b,d   Hoe, Hyang Sook ^a,f  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e Seoul National University   (South Korea)

^f GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3xTg AD mice; BTA EG4; Dendritic spine; Ras signaling

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; ANILINE DERIVATIVE; BENZOTHIAZOLE ANILINE; BENZOTHIAZOLE DERIVATIVE; BTA EG4; CENTRAL NERVOUS SYSTEM AGENTS; ETHYLENE GLYCOL DERIVATIVE; METHIONINE; PRESENILIN 1; RAS PROTEIN; TAU PROTEIN; TETRAETHYLENE GLYCOL DERIVATIVE; UNCLASSIFIED DRUG; VALINE;

AGE; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; BRAIN CORTEX; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITIC SPINE; DRUG MECHANISM; ENZYME ACTIVITY; GENE MUTATION; HETEROZYGOTE; HIPPOCAMPUS; LEARNING DISORDER; MALE; MEMORY DISORDER; MORPHOLOGY; MOUSE; NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; TREATMENT DURATION;

3XTG AD MICE; AD; ALZHEIMER'S DISEASE; AMYLOID-Β; AΒ; BTA-EG(4); DENDRITIC SPINE; RAS SIGNALING;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANILINE COMPOUNDS; ANIMALS; COGNITION DISORDERS; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; MUTATION; PRESENILIN-1; TAU PROTEINS;

EID: 84891102304     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.11.023     Document Type: Article

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