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Volumn 25, Issue 1, 2014, Pages 8-14

What are lipoproteins doing in the brainα

Author keywords

Astrocyte; Brain; Lipoprotein; Lipoprotein receptor; Metabolism; Neuron

Indexed keywords

APOLIPOPROTEIN E; CLUSTERIN; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN; LIPOPROTEIN LIPASE; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; LRP1 RECEPTOR; SCAVENGER RECEPTOR BI; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 84890987858     PISSN: 10432760     EISSN: 18793061     Source Type: Journal    
DOI: 10.1016/j.tem.2013.10.003     Document Type: Review
Times cited : (174)

References (68)
  • 1
    • 84858783222 scopus 로고    scopus 로고
    • Lipid-based carriers of microRNAs and intercellular communication
    • Vickers K.C., Remaley A.T. Lipid-based carriers of microRNAs and intercellular communication. Curr. Opin. Lipidol. 2012, 23:91-97.
    • (2012) Curr. Opin. Lipidol. , vol.23 , pp. 91-97
    • Vickers, K.C.1    Remaley, A.T.2
  • 2
    • 0034017316 scopus 로고    scopus 로고
    • Lipoproteins in the central nervous system
    • Ladu M.J., et al. Lipoproteins in the central nervous system. Ann. N. Y. Acad. Sci. 2000, 903:167-175.
    • (2000) Ann. N. Y. Acad. Sci. , vol.903 , pp. 167-175
    • Ladu, M.J.1
  • 3
    • 0036919653 scopus 로고    scopus 로고
    • CSF lipoproteins and Alzheimer's disease
    • Neely M.D., Montine T.J. CSF lipoproteins and Alzheimer's disease. J. Nutr. Health Aging 2002, 6:383-391.
    • (2002) J. Nutr. Health Aging , vol.6 , pp. 383-391
    • Neely, M.D.1    Montine, T.J.2
  • 4
    • 0034954555 scopus 로고    scopus 로고
    • Characterization of four lipoprotein classes in human cerebrospinal fluid
    • Koch S., et al. Characterization of four lipoprotein classes in human cerebrospinal fluid. J. Lipid Res. 2001, 42:1143-1151.
    • (2001) J. Lipid Res. , vol.42 , pp. 1143-1151
    • Koch, S.1
  • 5
    • 0017193105 scopus 로고
    • Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous system
    • Felgenhauer K., et al. Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous system. J. Neurol. Sci. 1976, 30:113-128.
    • (1976) J. Neurol. Sci. , vol.30 , pp. 113-128
    • Felgenhauer, K.1
  • 6
    • 0018775396 scopus 로고
    • A heterogenous, pore-vesicle membrane model for protein transfer from blood to cerebrospinal fluid at the choroid plexus
    • Rapoport S.I., Pettigrew K.D. A heterogenous, pore-vesicle membrane model for protein transfer from blood to cerebrospinal fluid at the choroid plexus. Microvasc. Res. 1979, 18:105-119.
    • (1979) Microvasc. Res. , vol.18 , pp. 105-119
    • Rapoport, S.I.1    Pettigrew, K.D.2
  • 7
    • 84868352782 scopus 로고    scopus 로고
    • Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice
    • Liu M., et al. Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice. Am. J. Physiol Regul. Integr. Comp Physiol 2012, 303:R903-R908.
    • (2012) Am. J. Physiol Regul. Integr. Comp Physiol , vol.303
    • Liu, M.1
  • 8
    • 77953248905 scopus 로고    scopus 로고
    • Formation and function of apolipoprotein E-containing lipoproteins in the nervous system
    • Vance J.E., Hayashi H. Formation and function of apolipoprotein E-containing lipoproteins in the nervous system. Biochim. Biophys. Acta 2010, 1801:806-818.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 806-818
    • Vance, J.E.1    Hayashi, H.2
  • 9
    • 0344011516 scopus 로고    scopus 로고
    • Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse
    • Quan G., et al. Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse. Brain Res. Dev. Brain Res. 2003, 146:87-98.
    • (2003) Brain Res. Dev. Brain Res. , vol.146 , pp. 87-98
    • Quan, G.1
  • 10
    • 79960459422 scopus 로고    scopus 로고
    • Cholesterol metabolism in neurons and astrocytes
    • Pfrieger F.W., Ungerer N. Cholesterol metabolism in neurons and astrocytes. Prog. Lipid Res. 2011, 50:357-371.
    • (2011) Prog. Lipid Res. , vol.50 , pp. 357-371
    • Pfrieger, F.W.1    Ungerer, N.2
  • 11
    • 84868516421 scopus 로고    scopus 로고
    • Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis
    • Chen J., et al. Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis. Biochim. Biophys. Acta 2013, 1831:263-275.
    • (2013) Biochim. Biophys. Acta , vol.1831 , pp. 263-275
    • Chen, J.1
  • 12
    • 77955566963 scopus 로고    scopus 로고
    • Apolipoproteins in the brain: implications for neurological and psychiatric disorders
    • Elliott D.A., et al. Apolipoproteins in the brain: implications for neurological and psychiatric disorders. Clin. Lipidol. 2010, 51:555-573.
    • (2010) Clin. Lipidol. , vol.51 , pp. 555-573
    • Elliott, D.A.1
  • 13
    • 0034663183 scopus 로고    scopus 로고
    • Apolipoprotein J (clusterin) and Alzheimer's disease
    • Calero M., et al. Apolipoprotein J (clusterin) and Alzheimer's disease. Microsc. Res. Tech. 2000, 50:305-315.
    • (2000) Microsc. Res. Tech. , vol.50 , pp. 305-315
    • Calero, M.1
  • 14
    • 0034802522 scopus 로고    scopus 로고
    • Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice
    • DeMattos R.B., et al. Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice. Neurochem. Int. 2001, 39:415-425.
    • (2001) Neurochem. Int. , vol.39 , pp. 415-425
    • DeMattos, R.B.1
  • 15
    • 33847240080 scopus 로고    scopus 로고
    • Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1
    • Hayashi H., et al. Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1. J. Neurosci. 2007, 27:1933-1941.
    • (2007) J. Neurosci. , vol.27 , pp. 1933-1941
    • Hayashi, H.1
  • 16
    • 84863504256 scopus 로고    scopus 로고
    • Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease
    • Holtzman D.M., et al. Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. Cold Spring Harb. Perspect. Med. 2012, 2:a006312.
    • (2012) Cold Spring Harb. Perspect. Med. , vol.2
    • Holtzman, D.M.1
  • 17
    • 84879058565 scopus 로고    scopus 로고
    • Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease
    • Martiskainen H., et al. Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease. Expert Opin. Ther. Targets 2013, 17:781-794.
    • (2013) Expert Opin. Ther. Targets , vol.17 , pp. 781-794
    • Martiskainen, H.1
  • 18
    • 84877326649 scopus 로고    scopus 로고
    • ApoE influences amyloid-beta (Abeta) clearance despite minimal apoE/Abeta association in physiological conditions
    • Verghese P.B., et al. ApoE influences amyloid-beta (Abeta) clearance despite minimal apoE/Abeta association in physiological conditions. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:E1807-E1816.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110
    • Verghese, P.B.1
  • 19
    • 83655169782 scopus 로고    scopus 로고
    • Preferential interactions between ApoE-containing lipoproteins and Abeta revealed by a detection method that combines size exclusion chromatography with non-reducing gel-shift
    • Ladu M.J., et al. Preferential interactions between ApoE-containing lipoproteins and Abeta revealed by a detection method that combines size exclusion chromatography with non-reducing gel-shift. Biochim. Biophys. Acta 2012, 1821:295-302.
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 295-302
    • Ladu, M.J.1
  • 20
    • 77953728876 scopus 로고    scopus 로고
    • Oxidative stress impairs learning and memory in apoE knockout mice
    • Evola M., et al. Oxidative stress impairs learning and memory in apoE knockout mice. Pharmacol. Biochem. Behav. 2010, 96:181-186.
    • (2010) Pharmacol. Biochem. Behav. , vol.96 , pp. 181-186
    • Evola, M.1
  • 21
    • 0032941603 scopus 로고    scopus 로고
    • A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E
    • Xu Y., et al. A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E. J. Lipid Res. 1999, 40:50-58.
    • (1999) J. Lipid Res. , vol.40 , pp. 50-58
    • Xu, Y.1
  • 22
    • 44949262269 scopus 로고    scopus 로고
    • Human apolipoprotein C-I expression in mice impairs learning and memory functions
    • Abildayeva K., et al. Human apolipoprotein C-I expression in mice impairs learning and memory functions. J. Lipid Res. 2008, 49:856-869.
    • (2008) J. Lipid Res. , vol.49 , pp. 856-869
    • Abildayeva, K.1
  • 23
    • 79953272165 scopus 로고    scopus 로고
    • Apolipoprotein CI knock-out mice display impaired memory functions
    • Berbee J.F., et al. Apolipoprotein CI knock-out mice display impaired memory functions. J. Alzheimers Dis. 2011, 23:737-747.
    • (2011) J. Alzheimers Dis. , vol.23 , pp. 737-747
    • Berbee, J.F.1
  • 24
    • 84866384152 scopus 로고    scopus 로고
    • Lipid rafts, synaptic transmission and plasticity: impact in age-related neurodegenerative diseases
    • Sebastiao A.M., et al. Lipid rafts, synaptic transmission and plasticity: impact in age-related neurodegenerative diseases. Neuropharmacology 2013, 64:97-107.
    • (2013) Neuropharmacology , vol.64 , pp. 97-107
    • Sebastiao, A.M.1
  • 25
    • 84858703061 scopus 로고    scopus 로고
    • Lipid rafts: a signalling platform linking lipoprotein metabolism to atherogenesis
    • Lemaire-Ewing S., et al. Lipid rafts: a signalling platform linking lipoprotein metabolism to atherogenesis. Atherosclerosis 2012, 221:303-310.
    • (2012) Atherosclerosis , vol.221 , pp. 303-310
    • Lemaire-Ewing, S.1
  • 26
    • 84877881574 scopus 로고    scopus 로고
    • Lipid raft disarrangement as a result of neuropathological progresses: A novel strategy for early diagnosisα
    • Marin R., et al. Lipid raft disarrangement as a result of neuropathological progresses: A novel strategy for early diagnosisα. Neuroscience 2013, 245:26-39.
    • (2013) Neuroscience , vol.245 , pp. 26-39
    • Marin, R.1
  • 27
    • 84864851111 scopus 로고    scopus 로고
    • Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers
    • Sorci-Thomas M.G., et al. Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers. J. Lipid Res. 2012, 53:1890-1909.
    • (2012) J. Lipid Res. , vol.53 , pp. 1890-1909
    • Sorci-Thomas, M.G.1
  • 28
    • 84862698102 scopus 로고    scopus 로고
    • Neuronal porosome proteome: molecular dynamics and architecture
    • Lee J.S., et al. Neuronal porosome proteome: molecular dynamics and architecture. J. Proteomics 2012, 75:3952-3962.
    • (2012) J. Proteomics , vol.75 , pp. 3952-3962
    • Lee, J.S.1
  • 29
    • 79952200124 scopus 로고    scopus 로고
    • Conformation states of the neuronal porosome complex
    • Cho W.J., et al. Conformation states of the neuronal porosome complex. Cell Biol. Int. 2010, 34:1129-1132.
    • (2010) Cell Biol. Int. , vol.34 , pp. 1129-1132
    • Cho, W.J.1
  • 30
    • 52649113152 scopus 로고    scopus 로고
    • EM 3D contour maps provide protein assembly at the nanoscale within the neuronal porosome complex
    • Cho W.J., et al. EM 3D contour maps provide protein assembly at the nanoscale within the neuronal porosome complex. J. Microsc. 2008, 232:106-111.
    • (2008) J. Microsc. , vol.232 , pp. 106-111
    • Cho, W.J.1
  • 31
    • 7044246147 scopus 로고    scopus 로고
    • Structure, isolation, composition and reconstitution of the neuronal fusion pore
    • Cho W.J., et al. Structure, isolation, composition and reconstitution of the neuronal fusion pore. Cell Biol. Int. 2004, 28:699-708.
    • (2004) Cell Biol. Int. , vol.28 , pp. 699-708
    • Cho, W.J.1
  • 32
    • 33745586296 scopus 로고    scopus 로고
    • Cholesterol is critical to the integrity of neuronal porosome/fusion pore
    • Jeremic A., et al. Cholesterol is critical to the integrity of neuronal porosome/fusion pore. Ultramicroscopy 2006, 106:674-677.
    • (2006) Ultramicroscopy , vol.106 , pp. 674-677
    • Jeremic, A.1
  • 33
    • 34548433783 scopus 로고    scopus 로고
    • Neuronal fusion pore assembly requires membrane cholesterol
    • Cho W.J., et al. Neuronal fusion pore assembly requires membrane cholesterol. Cell Biol. Int. 2007, 31:1301-1308.
    • (2007) Cell Biol. Int. , vol.31 , pp. 1301-1308
    • Cho, W.J.1
  • 34
    • 61349176514 scopus 로고    scopus 로고
    • Porosome in astrocytes
    • Lee J.S., et al. Porosome in astrocytes. J. Cell. Mol. Med. 2009, 13:365-372.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 365-372
    • Lee, J.S.1
  • 35
    • 58749104335 scopus 로고    scopus 로고
    • Nanoscale 3D contour map of protein assembly within the astrocyte porosome complex
    • Cho W.J., et al. Nanoscale 3D contour map of protein assembly within the astrocyte porosome complex. Cell Biol. Int. 2009, 33:224-229.
    • (2009) Cell Biol. Int. , vol.33 , pp. 224-229
    • Cho, W.J.1
  • 36
    • 0035140090 scopus 로고    scopus 로고
    • Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E
    • Goti D., et al. Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E. J. Neurochem. 2001, 76:498-508.
    • (2001) J. Neurochem. , vol.76 , pp. 498-508
    • Goti, D.1
  • 37
    • 0036193774 scopus 로고    scopus 로고
    • Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice
    • Mardones P., et al. Alpha-tocopherol metabolism is abnormal in scavenger receptor class B type I (SR-BI)-deficient mice. J. Nutr. 2002, 132:443-449.
    • (2002) J. Nutr. , vol.132 , pp. 443-449
    • Mardones, P.1
  • 38
    • 2542485364 scopus 로고    scopus 로고
    • Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model
    • Balazs Z., et al. Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model. J. Neurochem. 2004, 89:939-950.
    • (2004) J. Neurochem. , vol.89 , pp. 939-950
    • Balazs, Z.1
  • 39
    • 0037044840 scopus 로고    scopus 로고
    • ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells
    • Panzenboeck U., et al. ABCA1 and scavenger receptor class B, type I, are modulators of reverse sterol transport at an in vitro blood-brain barrier constituted of porcine brain capillary endothelial cells. J. Biol. Chem. 2002, 277:42781-42789.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42781-42789
    • Panzenboeck, U.1
  • 40
    • 4444315061 scopus 로고    scopus 로고
    • Scavenger receptor class B, type I mediates uptake of lipoprotein-associated phosphatidylcholine by primary porcine cerebrovascular endothelial cells
    • Sovic A., et al. Scavenger receptor class B, type I mediates uptake of lipoprotein-associated phosphatidylcholine by primary porcine cerebrovascular endothelial cells. Neurosci. Lett. 2004, 368:11-14.
    • (2004) Neurosci. Lett. , vol.368 , pp. 11-14
    • Sovic, A.1
  • 41
    • 43849109491 scopus 로고    scopus 로고
    • Increased locomotor activity in mice lacking the low-density lipoprotein receptor
    • Elder G.A., et al. Increased locomotor activity in mice lacking the low-density lipoprotein receptor. Behav. Brain Res. 2008, 191:256-265.
    • (2008) Behav. Brain Res. , vol.191 , pp. 256-265
    • Elder, G.A.1
  • 42
    • 82855172098 scopus 로고    scopus 로고
    • Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress
    • de O.J., et al. Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress. Neuroscience 2011, 197:99-106.
    • (2011) Neuroscience , vol.197 , pp. 99-106
    • de, O.J.1
  • 43
    • 84867557477 scopus 로고    scopus 로고
    • -/-): evidence of antioxidant imbalance and increased acetylcholinesterase activity in the prefrontal cortex
    • -/-): evidence of antioxidant imbalance and increased acetylcholinesterase activity in the prefrontal cortex. J. Alzheimers Dis. 2012, 32:495-511.
    • (2012) J. Alzheimers Dis. , vol.32 , pp. 495-511
    • Moreira, E.L.1
  • 44
    • 84866178329 scopus 로고    scopus 로고
    • A missense founder mutation in VLDLR is associated with dysequilibrium syndrome without quadrupedal locomotion
    • Ali B.R., et al. A missense founder mutation in VLDLR is associated with dysequilibrium syndrome without quadrupedal locomotion. BMC Med. Genet. 2012, 13:80.
    • (2012) BMC Med. Genet. , vol.13 , pp. 80
    • Ali, B.R.1
  • 45
    • 38349112372 scopus 로고    scopus 로고
    • Identification of a nonsense mutation in the very low-density lipoprotein receptor gene (VLDLR) in an Iranian family with dysequilibrium syndrome
    • Moheb L.A., et al. Identification of a nonsense mutation in the very low-density lipoprotein receptor gene (VLDLR) in an Iranian family with dysequilibrium syndrome. Eur. J. Hum. Genet. 2008, 16:270-273.
    • (2008) Eur. J. Hum. Genet. , vol.16 , pp. 270-273
    • Moheb, L.A.1
  • 46
    • 23944470349 scopus 로고    scopus 로고
    • Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification
    • Boycott K.M., et al. Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification. Am. J. Hum. Genet. 2005, 77:477-483.
    • (2005) Am. J. Hum. Genet. , vol.77 , pp. 477-483
    • Boycott, K.M.1
  • 47
    • 41949138166 scopus 로고    scopus 로고
    • Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans
    • Ozcelik T., et al. Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:4232-4236.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 4232-4236
    • Ozcelik, T.1
  • 48
    • 0033003134 scopus 로고    scopus 로고
    • Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2
    • Trommsdorff M., et al. Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell 1999, 97:689-701.
    • (1999) Cell , vol.97 , pp. 689-701
    • Trommsdorff, M.1
  • 49
    • 0037131401 scopus 로고    scopus 로고
    • Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning
    • Weeber E.J., et al. Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning. J. Biol. Chem. 2002, 277:39944-39952.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39944-39952
    • Weeber, E.J.1
  • 50
    • 79951938024 scopus 로고    scopus 로고
    • ApoE receptor 2 regulates synapse and dendritic spine formation
    • Dumanis S.B., et al. ApoE receptor 2 regulates synapse and dendritic spine formation. PLoS ONE 2011, 6:e17203.
    • (2011) PLoS ONE , vol.6
    • Dumanis, S.B.1
  • 51
    • 77951630116 scopus 로고    scopus 로고
    • The very low density lipoprotein receptor is not necessary for maintaining brain polyunsaturated fatty acid concentrations
    • Rahman T., et al. The very low density lipoprotein receptor is not necessary for maintaining brain polyunsaturated fatty acid concentrations. Prostaglandins Leukot. Essent. Fatty Acids 2010, 82:141-145.
    • (2010) Prostaglandins Leukot. Essent. Fatty Acids , vol.82 , pp. 141-145
    • Rahman, T.1
  • 52
    • 0030972045 scopus 로고    scopus 로고
    • No evidence for direct incorporation of esterified palmitic acid from plasma into brain lipids of awake adult rat
    • Purdon D., et al. No evidence for direct incorporation of esterified palmitic acid from plasma into brain lipids of awake adult rat. J. Lipid Res. 1997, 38:526-530.
    • (1997) J. Lipid Res. , vol.38 , pp. 526-530
    • Purdon, D.1
  • 53
    • 23744516021 scopus 로고    scopus 로고
    • Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2
    • Beffert U., et al. Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron 2005, 47:567-579.
    • (2005) Neuron , vol.47 , pp. 567-579
    • Beffert, U.1
  • 54
    • 84874088008 scopus 로고    scopus 로고
    • Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris
    • Fernandez-Castaneda A., et al. Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris. J. Biol. Chem. 2013, 288:4538-4548.
    • (2013) J. Biol. Chem. , vol.288 , pp. 4538-4548
    • Fernandez-Castaneda, A.1
  • 55
    • 78649788839 scopus 로고    scopus 로고
    • Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins
    • Matsuo M., et al. Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins. Biochim. Biophys. Acta 2011, 1811:31-38.
    • (2011) Biochim. Biophys. Acta , vol.1811 , pp. 31-38
    • Matsuo, M.1
  • 56
    • 50349092250 scopus 로고    scopus 로고
    • LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies
    • Lillis A.P., et al. LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol. Rev. 2008, 88:887-918.
    • (2008) Physiol. Rev. , vol.88 , pp. 887-918
    • Lillis, A.P.1
  • 57
    • 34748897213 scopus 로고    scopus 로고
    • Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1
    • Liu Q., et al. Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron 2007, 56:66-78.
    • (2007) Neuron , vol.56 , pp. 66-78
    • Liu, Q.1
  • 58
    • 78650347671 scopus 로고    scopus 로고
    • Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration
    • Liu Q., et al. Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. J. Neurosci. 2010, 30:17068-17078.
    • (2010) J. Neurosci. , vol.30 , pp. 17068-17078
    • Liu, Q.1
  • 59
    • 79960849792 scopus 로고    scopus 로고
    • Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models
    • Huang Y. Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models. Biochem. Soc. Trans. 2011, 39:924-932.
    • (2011) Biochem. Soc. Trans. , vol.39 , pp. 924-932
    • Huang, Y.1
  • 60
    • 77957289206 scopus 로고    scopus 로고
    • Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice
    • Buttini M., et al. Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice. Am. J. Pathol. 2010, 177:563-569.
    • (2010) Am. J. Pathol. , vol.177 , pp. 563-569
    • Buttini, M.1
  • 61
    • 84875111700 scopus 로고    scopus 로고
    • Cellular source-specific effects of apolipoprotein (apo) E4 on dendrite arborization and dendritic spine development
    • Jain S., et al. Cellular source-specific effects of apolipoprotein (apo) E4 on dendrite arborization and dendritic spine development. PLoS ONE 2013, 8:e59478.
    • (2013) PLoS ONE , vol.8
    • Jain, S.1
  • 62
    • 79956212740 scopus 로고    scopus 로고
    • Amyloid-beta protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease
    • Rolyan H., et al. Amyloid-beta protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease. J. Neural Transm. 2011, 118:699-712.
    • (2011) J. Neural Transm. , vol.118 , pp. 699-712
    • Rolyan, H.1
  • 63
    • 79851497711 scopus 로고    scopus 로고
    • Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system
    • Liu Q., et al. Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. PLoS Biol. 2011, 9:e1000575.
    • (2011) PLoS Biol. , vol.9
    • Liu, Q.1
  • 64
    • 4744352010 scopus 로고    scopus 로고
    • Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice
    • May P., et al. Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Mol. Cell. Biol. 2004, 24:8872-8883.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8872-8883
    • May, P.1
  • 65
    • 78650862930 scopus 로고    scopus 로고
    • Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity
    • Wang H., et al. Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. Cell Metab. 2011, 13:105-113.
    • (2011) Cell Metab. , vol.13 , pp. 105-113
    • Wang, H.1
  • 67
    • 84864189791 scopus 로고    scopus 로고
    • Lipoprotein lipase in the brain and nervous system
    • Wang H., Eckel R.H. Lipoprotein lipase in the brain and nervous system. Annu. Rev. Nutr. 2012, 32:147-160.
    • (2012) Annu. Rev. Nutr. , vol.32 , pp. 147-160
    • Wang, H.1    Eckel, R.H.2
  • 68
    • 65549113066 scopus 로고    scopus 로고
    • Presynaptic defects underlying impaired learning and memory function in lipoprotein lipase-deficient mice
    • Xian X., et al. Presynaptic defects underlying impaired learning and memory function in lipoprotein lipase-deficient mice. J. Neurosci. 2009, 29:4681-4685.
    • (2009) J. Neurosci. , vol.29 , pp. 4681-4685
    • Xian, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.