Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells

Stem Cell Reports

Volumn 1, Issue 6, 2013, Pages 499-508

  Hirose, Sho Ichi ^a   Takayama, Naoya ^a,b   Nakamura, Sou ^a,b   Nagasawa, Kazumichi ^c   Ochi, Kiyosumi ^a,b   Hirata, Shinji ^b   Yamazaki, Satoshi ^a   Yamaguchi, Tomoyuki ^a   Otsu, Makoto ^a   Sano, Shinya ^a   Takahashi, Nobuyasu ^d   Sawaguchi, Akira ^d   Ito, Mamoru ^e   Kato, Takashi ^d   Nakauchi, Hiromitsu ^a   Eto, Koji ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c WASEDA UNIVERSITY   (Japan)

^d UNIVERSITY OF MIYAZAKI   (Japan)

^e CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; PROTEIN BCL XL; TRANSCRIPTION FACTOR GATA 1; GATA1 PROTEIN, HUMAN; HEMOGLOBIN; HISTONE ACETYLTRANSFERASE PCAF; OXYGEN; P300-CBP-ASSOCIATED FACTOR; PROTEIN BCL X; RAF PROTEIN;

ARTICLE; CELL IMMORTALIZATION; CELL SIZE; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENUCLEATION; ERYTHROBLAST; ERYTHROPOIESIS; GENE EXPRESSION SYSTEM; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; HEMOGLOBIN SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; STEM CELL; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL DIFFERENTIATION; CULTURE TECHNIQUE; CYTOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; GENETICS; METABOLISM; NONOBESE DIABETIC MOUSE; ONCOGENE MYC; SCID MOUSE;

MUS;

ANIMALS; BCL-X PROTEIN; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL SIZE; EMBRYONIC STEM CELLS; ERYTHROBLASTS; ERYTHROPOIESIS; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; GENES, MYC; HEMOGLOBINS; HUMANS; MICE, INBRED NOD; MICE, SCID; OXYGEN; P300-CBP TRANSCRIPTION FACTORS; PLURIPOTENT STEM CELLS; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS C-RAF; TRANSDUCTION, GENETIC;

EID: 84890986391     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2013.10.010     Document Type: Article

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