Early anti-correlated BOLD signal changes of physiologic origin

NeuroImage

Volumn 87, Issue , 2014, Pages 287-296

  Bright, Molly G ^a,b   Bianciardi, Marta ^a,c   de Zwart, Jacco A ^a   Murphy, Kevin ^b   Duyn, Jeff H ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Anti correlated BOLD; Deactivation; FMRI; Negative BOLD; Physiology; Respiratory challenge

Indexed keywords

ADULT; ARTICLE; BOLD SIGNAL; BRAIN REGION; BREATHING; CONTROLLED STUDY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HUMAN; HYPOCAPNIA; PRIORITY JOURNAL; STIMULUS RESPONSE; TASK PERFORMANCE; VASOCONSTRICTION; VISUAL STIMULATION; WHITE MATTER; YOUNG ADULT;

ANTI-CORRELATED BOLD; DEACTIVATION; FMRI; NEGATIVE BOLD; PHYSIOLOGY; RESPIRATORY CHALLENGE;

ADULT; BRAIN; BRAIN MAPPING; FEMALE; HEMODYNAMICS; HUMANS; HYPOCAPNIA; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN; RESPIRATION; YOUNG ADULT;

EID: 84890933895     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2013.10.055     Document Type: Article

References (35)

1. Bandettini P.A., Wong E.C., Hinks R.S., Tikofsky R.S., Hyde J.S. Time course EPI of human brain function during task activation. Magn. Reson. Med. 1992, 25:390-397.
2. Bianciardi M., Fukunaga M., van Gelderen P., de Zwart J.A., Duyn J.H. Negative BOLD-fMRI signals in large cerebral veins. J. Cereb. Blood Flow Metab. 2011, 31:401-412.
3. Birn R.M., Smith M.A., Jones T.B., Bandettini P.A. The respiration response function: the temporal dynamics of fMRI signal fluctuations related to changes in respiration. NeuroImage 2008, 40:644-654.
4. Blockley N.P., Driver I.D., Francis S.T., Fisher J.A., Gowland P.A. An improved method for acquiring cerebrovascular reactivity maps. Magn. Reson. Med. 2011, 65:1278-1286.
5. Boxerman J.L., Hamberg L.M., Rosen B.R., Weisskoff R.M. MR contrast due to intravascular magnetic susceptibility perturbations. Magn. Reson. Med. 1995, 34:555-566.
6. Brian J.E. Carbon dioxide and the cerebral circulation. Anesthesiology 1998, 88:1365-1386.
7. Bright M.G., Murphy K. Removing motion and physiological artifacts from intrinsic BOLD fluctuations using short echo data. NeuroImage 2013, 64:526-537.
8. Bright M.G., Bulte D.P., Jezzard P., Duyn J.H. Characterization of regional heterogeneity in cerebrovascular reactivity dynamics using novel hypocapnia task and BOLD fMRI. NeuroImage 2009, 48:166-175.
9. Bright M.G., Bulte D.P., Jezzard P., Duyn J.H. Characterizing the BOLD response to transient respiratory challenges at 7 Tesla. Presented at the 11th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Montreal, Canada 2011.
10. Buxton R.B. Interpreting oxygenation-based neuroimaging signals: the importance and the challenge of understanding brain oxygen metabolism. Front. Neuroenerg. 2010, 2:8. 10.3389/fnene.2010.00008.
11. Buxton R.B. Dynamic models of BOLD contrast. NeuroImage 2012, 62:953-961.
12. Buxton R.B., Wong E.C., Frank L.R. Dynamics of blood flow and oxygenation changes during brain activation: the balloon model. Magn. Reson. Med. 1998, 39:855-864.
13. de Zwart J.A., van Gelderen P., Jansma J.M., Fukunaga M., Bianciardi M., Duyn J.H. Hemodynamic nonlinearities affect BOLD fMRI response timing and amplitude. NeuroImage 2009, 47:1649-1658.
14. Fukunaga M., Horovitz S.G., de Zwart J.A., van Gelderen P., Balkin T.J., Braun A.R., Duyn J.H. Metabolic origin of BOLD signal fluctuations in the absence of stimuli. J. Cereb. Blood Flow Metab. 2008, 28:1377-1387.
15. Goense J., Merkle H., Logothetis N.K. High-resolution fMRI reveals laminar differences in neurovascular coupling between positive and negative bold responses. Neuron 2012, 76:629-639.
16. Gonzalez-Castillo J., Saad Z.S., Handwerker D.A., Inati S.J., Brenowitz N., Bandettini P.A. Whole-brain, time-locked activation with simple tasks revealed using massive averaging and model-free analysis. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:5487-5492.
17. Hall E.L., Driver I.D., Croal P.L., Francis S.T., Gowland P.A., Morris P.G., Brookes M.J. The effect of hypercapnia on resting and stimulus induced MEG signals. NeuroImage 2011, 58:1034-1043.
18. Harel N., Lee S.-P., Nagaoka T., Kim D.-S., Kim S.-G. Origin of negative blood oxygenation level-dependent fMRI signals. J. Cereb. Blood Flow Metab. 2002, 22:908-917.
19. Kastrup A., Baudewig J., Schnaudigel S., Huonker R., Becker L., Sohns J.M., Dechent P., Klingner C., Witte O.W. Behavioral correlates of negative BOLD signal changes in the primary somatosensory cortex. NeuroImage 2008, 41:1364-1371.
20. Kellman P., Gelderen P.V., de Zwart J.A., Duyn J.H. Method for functional MRI mapping of nonlinear response. NeuroImage 2003, 19:190-199.
21. Kwong K.K., Belliveau J.W., Chesler D.A., Goldberg I.E., Weisskoff R.M., Poncelet B.P., Kennedy D.N., Hoppel B.E., Cohen M.S., Turner R. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. Sci. 1992, 89:5675-5679.
22. Leopold D.A., Maier A. Ongoing physiological processes in the cerebral cortex. NeuroImage 2012, 62:2190-2200.
23. Mandell D.M., Han J.S., Poublanc J., Crawley A.P., Kassner A., Fisher J.A., Mikulis D.J. Selective reduction of blood flow to white matter during hypercapnia corresponds with leukoaraiosis. Stroke 2008, 39:1993-1998.
24. McKay L.C., Evans K.C., Frackowiak R.S.J., Corfield D.R. Neural correlates of voluntary breathing in humans. J. Appl. Physiol. 2003, 95:1170-1178.
25. Mokri B. The Monro-Kellie hypothesis: applications in CSF volume depletion. Neurology 2001, 56:1746-1748.
26. Murphy K., Birn R.M., Handwerker D.A., Jones T.B., Bandettini P.A. The impact of global signal regression on resting state correlations: are anti-correlated networks introduced?. NeuroImage 2009, 44:893-905.
27. Ogawa S., Tank D.W., Menon R., Ellermann J.M., Kim S.G., Merkle H., Ugurbil K. Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc. Natl. Acad. Sci. 1992, 89:5951-5955.
28. Pasley B.N., Inglis B.A., Freeman R.D. Analysis of oxygen metabolism implies a neural origin for the negative BOLD response in human visual cortex. NeuroImage 2007, 36:269-276.
29. Piechnik S.K., Evans J., Bary L.H., Wise R.G., Jezzard P. Functional changes in CSF volume estimated using measurement of water T2relaxation. Magn. Reson. Med. 2009, 61:579-586.
30. Schäfer K., Blankenburg F., Kupers R., Grüner J.M., Law I., Lauritzen M., Larsson H.B.W. Negative BOLD signal changes in ipsilateral primary somatosensory cortex are associated with perfusion decreases and behavioral evidence for functional inhibition. NeuroImage 2012, 59:3119-3127.
31. Shmuel A., Augath M., Oeltermann A., Logothetis N.K. Negative functional MRI response correlates with decreases in neuronal activity in monkey visual area V1. Nat. Neurosci. 2006, 9:569-577.
32. Silva A.C., Koretsky A.P., Duyn J.H. Functional MRI impulse response for BOLD and CBV contrast in rat somatosensory cortex. Magn. Reson. Med. 2007, 57:1110-1118.
33. van Gelderen P., de Zwart J.A., Starewicz P., Hinks R.S., Duyn J.H. Real-time shimming to compensate for respiration-induced B0 fluctuations. Magn. Reson. Med. 2007, 57:362-368.
34. Zappe A.C., Uludag K., Oeltermann A., Ugurbil K., Logothetis N.K. The influence of moderate hypercapnia on neural activity in the anesthetized nonhuman primate. Cereb. Cortex 2008, 18:2666-2673.
35. Zhang Y., Brady M., Smith S. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Trans. Med. Imaging 2001, 20(1):45-57. (Jan).