Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn(2) N-Alkylpyridylporphyrins

Journal of Biological Chemistry

Volumn 288, Issue 51, 2013, Pages 36579-36588

  Ezzeddine, Rima ^a   Al Banaw, Anwar ^a   Tovmasyan, Artak ^b   Craik, James D ^a   Batinic Haberle, Ines ^b   Benov, Ludmil T ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL SUBSTITUENT; CELLULAR COMPARTMENTS; CELLULAR STRUCTURE; CELLULAR UPTAKE; LENGTH AND POSITION; MOLECULAR CHARACTERISTICS; MOLECULAR SHAPES; SUBCELLULAR LOCALIZATIONS;

CHEMICAL MODIFICATION; MOLECULES; PORPHYRINS;

ZINC;

ANION; PHOTOSENSITIZING AGENT; PORPHYRIN DERIVATIVE; UNCLASSIFIED DRUG; ZINC N ALKYLPYRIDYLPORPHYRIN DERIVATIVE;

ARTICLE; CELL MEMBRANE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HYDROPHILICITY; LIPOPHILICITY; LYSOSOME; MITOCHONDRION; PHOTODYNAMICS; PHOTOTOXICITY; PRIORITY JOURNAL; STATIC ELECTRICITY;

CELL PROLIFERATION; CELLULAR UPTAKE; FLUORESCENCE; MEMBRANE BILAYER; PHOTODYNAMIC THERAPY; PHOTOSENSITIZER; PHOTOTOXICITY; PORPHYRIN; SUBCELLULAR DISTRIBUTION; ZN PORPHYRIN;

BIOLOGICAL TRANSPORT; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; HUMANS; ISOMERISM; LIGHT; LYSOSOMES; MCF-7 CELLS; METALLOPORPHYRINS; MITOCHONDRIA; RADIATION-SENSITIZING AGENTS; STATIC ELECTRICITY; ZINC;

EID: 84890925891     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.511642     Document Type: Article

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