BF3·etherate-mediated Friedel-Crafts arylation of 2-hydroxy-1,4-benzoxazines: Synthesis of 2-aryl-1,4-benzoxazine derivatives

Journal of Organic Chemistry

Volumn 78, Issue 24, 2013, Pages 12819-12824

  Naganaboina, Ram Tilak ^a   Peddinti, Rama Krishna ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLATIONS; CARBON-CARBON BOND FORMATION; ELECTRON-RICH ARENES; FRIEDEL-CRAFTS;

CHEMICAL REACTIONS;

AROMATIC COMPOUNDS;

BENZOXAZINE DERIVATIVE; METHYL 2 [2 (2 HYDROXY 5 METHYLPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (2 HYDROXY 5 METHYLPHENYL) 6 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (2 HYDROXY 5 METHYLPHENYL) 7 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (2,4 DIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (2,4 DIMETHOXYPHENYL) 6 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (2,4 DIMETHOXYPHENYL) 7 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (2,4,6 TRIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (3 HYDROXY 2,4 DIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (3 HYDROXY 2,4 DIMETHOXYPHENYL) 6 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (3 HYDROXY 2,4 DIMETHOXYPHENYL) 7 METHYL 2H BENZO[B][1,4]OXACIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 6 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [2 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 7 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 BROMO 2 (2 HYDROXY 5 METHYLPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 BROMO 2 (2,4 DIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 BROMO 2 (2,4,6 TRIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 BROMO 2 (3 HYDROXY 2,4 DIMETHOXYPHENYL) 6 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 BROMO 2 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 CHLORO 2 (2 HYDROXY 5 METHYLPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 CHLORO 2 (2,4 DIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 CHLORO 2 (2,4,6 TRIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 CHLORO 2 (3 HYDROXY 2,4 DIMETHOXYPHENYL) 6 METHYL 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 CHLORO 2 (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 METHYL 2 (2,4,6 TRIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 TERT BUTYL (3,5 DI TERT BUTYL 4 HYDROXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 TERT BUTYL 2 (2 HYDROXY 5 METHYLPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 TERT BUTYL 2 (2,4 DIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [6 TERT BUTYLL 2 (2,4,6 TRIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; METHYL 2 [7 METHYL 2 (2,4,6 TRIMETHOXYPHENYL) 2H BENZO[B][1,4]OXAZIN 3 (4H) YLIDENE]ACETATE; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; DRUG SYNTHESIS; ELECTRON; FRIEDEL CRAFTS REACTION; INFRARED SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; THIN LAYER CHROMATOGRAPHY; X RAY ANALYSIS;

EID: 84890905180     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo402254n     Document Type: Article

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