Agonistic anti-human Fas monoclonal antibody induces fibroblast-like synoviocyte apoptosis in haemophilic arthropathy: Potential therapeutic implications

Haemophilia

Volumn 20, Issue 1, 2014, Pages

  Romano, E ^a   Manetti, M ^b   Peruzzi, F ^a   Melchiorre, D ^a   Milia, A F ^b   Bellando Randone, S ^a   Nishioka, K ^c   Innocenti, M ^d   Carulli, C ^d   Linari, S ^a   Morfini, M ^a   Ibba Manneschi, L ^b   Matucci Cerinic, M ^a   Guiducci, S ^a  

^a CAREGGI UNIVERSITY HOSPITAL   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c TOKYO MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Agonistic anti Fas IgM antibody; Apoptosis; Fibroblast like synoviocytes; Haemophilic arthropathy; Synovitis

Indexed keywords

CASPASE 3; FAS ANTIBODY; FAS ANTIGEN; FAS MONOCLONAL ANTIBODY; FIBROBLAST GROWTH FACTOR 2; IMMUNOGLOBULIN M ANTIBODY; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL VIABILITY; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FIBROBLAST LIKE SYNOVIOCYTE; HEMOPHILIC ARTHROPATHY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATORY CELL; JOINT BIOPSY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM; WESTERN BLOTTING;

AGONISTIC ANTI-FAS IGM ANTIBODY; APOPTOSIS; FIBROBLAST-LIKE SYNOVIOCYTES; HAEMOPHILIC ARTHROPATHY; SYNOVITIS;

ADULT; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; APOPTOSIS; ARTHRITIS, RHEUMATOID; CASPASE 3; CELL SURVIVAL; FIBROBLASTS; HEMARTHROSIS; HEMOPHILIA A; HUMANS; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; SYNOVIAL MEMBRANE; YOUNG ADULT;

EID: 84890859386     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/hae.12304     Document Type: Article

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