ARG098, a novel anti-human Fas antibody, suppresses synovial hyperplasia and prevents cartilage destruction in a severe combined immunodeficient-HuRAg mouse model

BMC Musculoskeletal Disorders

Volumn 11, Issue , 2010, Pages

  Odani Kawabata, Noriko ^a   Takai Imamura, Miwa ^a   Katsuta, Osamu ^a   Nakamura, Hiroshi ^b   Nishioka, Kusuki ^b   Funahashi, Keiko ^c   Matsubara, Tsukasa ^c   Sasano, Minoru ^a   Aono, Hiroyuki ^a  

^a SANTEN PHARMACEUTICAL CO LTD   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Matsubara Mayflower Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARG 098; FAS ANTIBODY; UNCLASSIFIED DRUG; FAS ANTIGEN; HYBRID PROTEIN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL VIABILITY; CONTROLLED STUDY; DRUG BINDING; DRUG POTENCY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; RHEUMATOID ARTHRITIS; SEVERE COMBINED IMMUNODEFICIENCY; SYNOVIUM; ANIMAL; C57BL MOUSE; CELL CULTURE; CHONDROPATHY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HYPERPLASIA; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; MOUSE MUTANT; PATHOLOGY; SYNTHESIS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; CARTILAGE DISEASES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HUMANS; HYPERPLASIA; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; MICE, SCID; RECOMBINANT FUSION PROTEINS; SYNOVIAL MEMBRANE;

EID: 77957109239     PISSN: None     EISSN: 14712474     Source Type: Journal    
DOI: 10.1186/1471-2474-11-221     Document Type: Article

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