Metabolic stress-induced microRNA and mRNA expression profiles of human fibroblasts

Experimental Cell Research

Volumn 320, Issue 2, 2014, Pages 343-353

  Kálmán, Sára ^a   Garbett, Krassimira A ^b   Vereczkei, Andrea ^a,c   Shelton, Richard C ^d   Korade, Željka ^a,e   Mirnics, Károly ^a,b,e  

^a UNIVERSITY OF SZEGED   (Hungary)

^b VANDERBILT UNIVERSITY   (United States)

^c SEMMELWEIS UNIVERSITY   (Hungary)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Galactose; Human fibroblast; Lipid; MiRNA; MRNA; Profiling; QPCR; Stress

Indexed keywords

CHOLESTEROL; GALACTOSE; GLUCOSE; LIPID; MESSENGER RNA; MICRO RNA 129 3P; MICRO RNA 146B 5P; MICRO RNA 543; MICRO RNA 550A; MICRORNA; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIPOLAR DISORDER; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; FOLLOW UP; GENE EXPRESSION; GENE EXPRESSION PROFILING; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR DEPRESSION; MALE; METABOLIC STRESS; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA ISOLATION; SCHIZOPHRENIA; SKIN BIOPSY; UPREGULATION;

GALACTOSE; HUMAN FIBROBLAST; LIPID; MIRNA; MRNA; PROFILING; QPCR; STRESS;

CELLS, CULTURED; CLUSTER ANALYSIS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MALE; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; TRANSCRIPTOME;

EID: 84890858741     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.10.019     Document Type: Article

References (33)

1. Horvath S., Janka Z., Mirnics K. Analyzing schizophrenia by DNA microarrays. Biol. Psychiatry 2010, 69:157-162.
2. Mirnics K., Lewis D.A. Genes and subtypes of schizophrenia. Trends Mol. Med. 2001, 7:281-283.
3. Glorioso C., Sabatini M., Unger T., Hashimoto T., Monteggia L.M., et al. Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Mol. Psychiatry 2006, 11:633-648.
4. Garbett K.A., Horvath S., Ebert P.J., Schmidt M.J., Lwin K., et al. Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression. Mol. Psychiatry 2010, 15:987-995.
5. Garbett K.A., Hsiao E.Y., Kalman S., Patterson P.H., Mirnics K. Effects of maternal immune activation on gene expression patterns in the fetal brain. Transl. Psychiatry 2012, 2:e98.
6. Akin D., Manier D.H., Sanders-Bush E., Shelton R.C. Signal transduction abnormalities in melancholic depression. Int. J. Neuropsychopharmacol. 2005, 8:5-16.
7. Gibson S.A., Korade Z., Shelton R.C. Oxidative stress and glutathione response in tissue cultures from persons with major depression. J. Psychiatry Res. 2012, 46:1326-1332.
8. de Nadal E., Ammerer G., Posas F. Controlling gene expression in response to stress. Nat. Rev. Genet. 2011, 12:833-845.
9. Marroquin L.D., Hynes J., Dykens J.A., Jamieson J.D., Will Y. Circumventing the Crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants. Toxicol. Sci. 2007, 97:539-547.
10. Jacobs R.A., Sly W.S., Majerus P.W. The regulation of fatty acid biosynthesis in human skin fibroblasts. J. Biol. Chem. 1973, 248:1268-1276.
11. Raff R.A. Induction of fatty acid synthesis in cultured mammalian cells: effects of cycloheximide and X-rays. J. Cell Physiol. 1970, 75:341-351.
12. Bensaude I., Callahan J., Philippart M. Fabry's disease as an -galactosidosis: evidence for an -configuration in trihexosyl ceramide. Biochem. Biophys. Res. Commun. 1971, 43:913-918.
13. Malan-Muller S., Hemmings S.M., Seedat S. Big effects of small RNAs: a review of microRNAs in anxiety. Mol. Neurobiol. 2012, 47:726-739.
14. Inui M., Martello G., Piccolo S. MicroRNA control of signal transduction. Nat. Rev. Mol. Cell Biol. 2010, 11:252-263.
15. Manier D.H., Eiring A., Shelton R.C., Sulser F. Beta-adrenoceptor-linked protein kinase A (PKA) activity in human fibroblasts from normal subjects and from patients with major depression. Neuropsychopharmacology. 1996, 15:555-561.
16. APA Diagnostic and Statistical Manual of Mental Disorders 2000, American Psychiatric Association, Washington, DC.
17. Unger T., Korade Z., Lazarov O., Terrano D., Sisodia S.S., Mirnics K. True and false discovery in DNA microarray experiments: transcriptome changes in the hippocampus of presenilin 1 mutant mice. Methods 2005, 37(3):261-273.
18. Mirnics K. Microarrays in brain research: data quality and limitations revisited. Curr. Genomics 2006, 7:11-17.
19. Reich M., Liefeld T., Gould J., Lerner J., Tamayo P., et al. Genepattern 2.0. Nat. Genet. 2006, 38:500-501.
20. Subramanian A., Kuehn H., Gould J., Tamayo P., Mesirov J.P. GSEA-P: a desktop application for gene set enrichment analysis. Bioinformatics 2007, 23:3251-3253.
21. Wang X. miRDB: a microRNA target prediction and functional annotation database with a wiki interface. RNA 2008, 14:1012-1017.
22. Tsai K.W., Wu C.W., Hu L.Y., Li S.C., Liao Y.L., et al. Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. Int. J. Cancer 2011, 129:2600-2610.
23. Cao J., Shen Y., Zhu L., Xu Y., Zhou Y., et al. miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics. Nat. Cell. Biol. 2012, 14:697-706.
24. Kutty R.K., Nagineni C.N., Samuel W., Vijayasarathy C., Jaworski C., et al. Differential regulation of microRNA-146a and microRNA-146b-5p in human retinal pigment epithelial cells by interleukin-1beta, tumor necrosis factor-alpha, and interferon-gamma. Mol. Vis. 2013, 19:737-750.
25. Takahashi N., Nakaoka T., Yamashita N. Profiling of immune-related microRNA expression in human cord blood and adult peripheral blood cells upon proinflammatory stimulation. Eur. J. Haematol. 2012, 88:31-38.
26. Hulsmans M., Van Dooren E., Mathieu C., Holvoet P. Decrease of miR-146b-5p in monocytes during obesity is associated with loss of the anti-inflammatory but not insulin signaling action of adiponectin. PLoS One 2012, 7:e32794.
27. Geraldo M.V., Yamashita A.S., Kimura E.T. MicroRNA miR-146b-5p regulates signal transduction of TGF-beta by repressing SMAD4 in thyroid cancer. Oncogene 2011, 31:1910-1922.
28. Garcia A.I., Buisson M., Bertrand P., Rimokh R., Rouleau E., et al. Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers. EMBO Mol. Med. 2011, 3:279-290.
29. Katakowski M., Zheng X., Jiang F., Rogers T., Szalad A., et al. MiR-146b-5p suppresses EGFR expression and reduces in vitro migration and invasion of glioma. Cancer Invest. 2010, 28:1024-1030.
30. Michel M., Schmidt M.J., Mirnics K. Immune system gene dysregulation in autism and schizophrenia. Dev. Neurobiol. 2012, 72:1277-1287.
31. Naydenov A.V., MacDonald M.L., Ongur D., Konradi C. Differences in lymphocyte electron transport gene expression levels between subjects with bipolar disorder and normal controls in response to glucose deprivation stress. Arch. Gen. Psychiatry 2007, 64:555-564.
32. Manier D.H., Shelton R.C., Ellis T.C., Peterson C.S., Eiring A., et al. Human fibroblasts as a relevant model to study signal transduction in affective disorders. J. Affect. Disord. 2000, 61:51-58.
33. Kang H.J., Kawasawa Y.I., Cheng F., Zhu Y., Xu X., Li M., Sousa A.M., Pletikos M., Meyer K.A., Sedmak G., Guennel T., Shin Y., Johnson M.B., Krsnik Z., Mayer S., Fertuzinhos S., Umlauf S., Lisgo S.N., Vortmeyer A., Weinberger D.R., Mane S., Hyde T.M., Huttner A., Reimers M., Kleinman J.E., Sestan N. Spatio-temporal transcriptome of the human brain. Nature 2011, 478(7370):483-489.