Decrease of miR-146b-5p in monocytes during obesity is associated with loss of the anti-inflammatory but not insulin signaling action of adiponectin

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Hulsmans, Maarten ^a   van Dooren, Els ^a   Mathieu, Chantal ^b   Holvoet, Paul ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; BETA ACTIN; I KAPPA B KINASE GAMMA; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; MANGANESE SUPEROXIDE DISMUTASE; MICRORNA; MICRORNA 146B 5P; REACTIVE OXYGEN METABOLITE; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK3 PROTEIN, HUMAN; MIRN146 MICRORNA, HUMAN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN METABOLISM; INTRACELLULAR SIGNALING; MALE; MONOCYTE; OBESITY; OXIDATIVE STRESS; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; BIOLOGICAL MODEL; BIOSYNTHESIS; BLOOD; CASE CONTROL STUDY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

ADIPONECTIN; ADULT; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INSULIN; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MALE; MICRORNAS; MODELS, BIOLOGICAL; MONOCYTES; NF-KAPPA B; OBESITY; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84857681898     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032794     Document Type: Article

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