The metabolism of trifluoperazine (TFP) exhibits atypical kinetic behavior in both human liver microsomes (HLMs) and monkey liver microsomes (MyLM)

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 39, Issue 4, 2014, Pages 335-337

  Xiao, Jin Fang ^a   Liu, Xiao Jun ^a   Liu, Gao Wang ^a   Yang, Xue Ying ^a   Xiao, Pan ^a   Hou, Xiao Min ^a   Wang, Hai Tang ^a   Tang, Jian Jun ^a   Zhang, Ya Ting ^a   Zhen, Chen ^a   Fang, Hai Hong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Substrate inhibition model; Trifluoperazine (TFP); UDP glucuronosyltransferase (UGT) 1A4

Indexed keywords

TRIFLUOPERAZINE;

ANIMAL; HUMAN; LIVER MICROSOME; MACACA FASCICULARIS; METABOLISM; SPECIES DIFFERENCE;

ANIMALS; HUMANS; MACACA FASCICULARIS; MICROSOMES, LIVER; SPECIES SPECIFICITY; TRIFLUOPERAZINE;

EID: 84890832410     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/s13318-013-0163-8     Document Type: Article

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