Gossypol exhibits a strong influence towards UDP-glucuronosyltransferase (UGT) 1A1, 1A9 and 2B7-mediated metabolism of xenobiotics and endogenous substances

Molecules

Volumn 17, Issue 5, 2012, Pages 4896-4903

  Zhang, Yong Sheng ^a   Yuan, Jun ^a   Fang, Zhong Ze ^b   Tu, Yan Yang ^a   Hu, Cui Min ^c   Li, Gan ^a   Wang, Liang ^a   Deng, Jian Ping ^a   Yao, Jia Jiu ^a   Li, Hai Rong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NONE   (United States)

Author keywords

Enzyme inhibition; Gossypol; UDP glucuronosyltransferase (UGT)

Indexed keywords

BILIRUBIN URIDINE DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; BILIRUBIN URIDINE-DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; ENZYME INHIBITOR; ESTRADIOL; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; GOSSYPOL; ISOENZYME; PROPOFOL; URIDINE DIPHOSPHATE GLUCURONIC ACID; XENOBIOTIC AGENT; ZIDOVUDINE;

ARTICLE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME SPECIFICITY; ENZYMOLOGY; HUMAN; KINETICS; LIVER MICROSOME; METABOLISM;

ENZYME INHIBITORS; ESTRADIOL; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; GOSSYPOL; HUMANS; ISOENZYMES; KINETICS; MICROSOMES, LIVER; PROPOFOL; SUBSTRATE SPECIFICITY; URIDINE DIPHOSPHATE GLUCURONIC ACID; XENOBIOTICS; ZIDOVUDINE;

EID: 84861525720     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17054896     Document Type: Article

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