-
2
-
-
4344567362
-
Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice
-
Serganova I, Doubrovin M, Vider J, et al. Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice. Cancer Res. 2004;64(17): 6101-6108.
-
(2004)
Cancer Res
, vol.64
, Issue.17
, pp. 6101-6108
-
-
Serganova, I.1
Doubrovin, M.2
Vider, J.3
-
3
-
-
84855708762
-
HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway
-
Qiang L, Wu T, Zhang HW, et al. HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway. Cell Death Differ. 2012;19(2):284-294.
-
(2012)
Cell Death Differ
, vol.19
, Issue.2
, pp. 284-294
-
-
Qiang, L.1
Wu, T.2
Zhang, H.W.3
-
4
-
-
33751256842
-
Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: Implications for angiogenesis and glioma cell invasion
-
Zagzag D, Lukyanov Y, Lan L, et al. Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Lab Invest. 2006;86(12):1221-1232.
-
(2006)
Lab Invest
, vol.86
, Issue.12
, pp. 1221-1232
-
-
Zagzag, D.1
Lukyanov, Y.2
Lan, L.3
-
5
-
-
34250340883
-
Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF- induced cell migration
-
Eckerich C, Zapf S, Fillbrandt R, et al. Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF- induced cell migration. Int J Cancer. 2007;121(2):276-283.
-
(2007)
Int J Cancer
, vol.121
, Issue.2
, pp. 276-283
-
-
Eckerich, C.1
Zapf, S.2
Fillbrandt, R.3
-
6
-
-
71949097180
-
HIF-1alpha blocks differentiation of malignant gliomas
-
Lu H, Li Y, Shu M, et al. HIF-1alpha blocks differentiation of malignant gliomas. FEBS J. 2009;276(24):7291-7304.
-
(2009)
FEBS J
, vol.276
, Issue.24
, pp. 7291-7304
-
-
Lu, H.1
Li, Y.2
Shu, M.3
-
7
-
-
1642387020
-
Hypoxia-inducible factor (HIF-1)alpha: Its protein stability and biological functions
-
Lee JW, Bae SH, Jeong JW, et al. Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med. 2004;36(1):1-12.
-
(2004)
Exp Mol Med
, vol.36
, Issue.1
, pp. 1-12
-
-
Lee, J.W.1
Bae, S.H.2
Jeong, J.W.3
-
8
-
-
78649396776
-
Cycling hypoxia increases U87 glioma cell radioresistance via ROS induced higher and long-term HIF-1 signal transduction activity
-
Hsieh CH, Lee CH, Liang JA, et al. Cycling hypoxia increases U87 glioma cell radioresistance via ROS induced higher and long-term HIF-1 signal transduction activity. Oncol Rep. 2010;24(6):1629-1636.
-
(2010)
Oncol Rep
, vol.24
, Issue.6
, pp. 1629-1636
-
-
Hsieh, C.H.1
Lee, C.H.2
Liang, J.A.3
-
9
-
-
80052831432
-
NADPH oxidase subunit 4-mediated reactive oxygen species contribute to cycling hypoxia-promoted tumor progression in glioblastoma multiforme
-
Hsieh CH, Shyu WC, Chiang CY, et al. NADPH oxidase subunit 4-mediated reactive oxygen species contribute to cycling hypoxia-promoted tumor progression in glioblastoma multiforme. PLoS One. 2011;6(9):e23945.
-
(2011)
PLoS One
, vol.6
, Issue.9
-
-
Hsieh, C.H.1
Shyu, W.C.2
Chiang, C.Y.3
-
10
-
-
77958569924
-
Nitric oxide-mediated augmentation of neutrophil reactive oxygen and nitrogen species formation: Critical use of probes
-
Kumar S, Patel S, Jyoti A, et al. Nitric oxide-mediated augmentation of neutrophil reactive oxygen and nitrogen species formation: Critical use of probes. Cytometry A. 2010;77(11):1038-1048.
-
(2010)
Cytometry A
, vol.77
, Issue.11
, pp. 1038-1048
-
-
Kumar, S.1
Patel, S.2
Jyoti, A.3
-
11
-
-
0027427588
-
Characterization of hypoxia inducible factor 1 and regulation of DNA blinding activity by hypoxia
-
Wang GL, Semenza GL. Characterization of hypoxia inducible factor 1 and regulation of DNA blinding activity by hypoxia. J Biol Chem. 1993;268(29):21513-21518.
-
(1993)
J Biol Chem
, vol.268
, Issue.29
, pp. 21513-21518
-
-
Wang, G.L.1
Semenza, G.L.2
-
12
-
-
54249164450
-
HIF-1 regulation: Not so easy come, easy go
-
Yee Koh M, Spivak-Kroizman TR, Powis G. HIF-1 regulation: not so easy come, easy go. Trends Biochem Sci. 2008;33(11):526-534.
-
(2008)
Trends Biochem Sci
, vol.33
, Issue.11
, pp. 526-534
-
-
Yee, K.M.1
Spivak-Kroizman, T.R.2
Powis, G.3
-
13
-
-
65749102069
-
The HIF-1-active microenvironment: An environmental target for cancer therapy
-
Kizaka-Kondoh S, Tanaka S, Harada H, et al. The HIF-1-active microenvironment: an environmental target for cancer therapy. Adv Drug Deliv Rev. 2009;61(7-8): 623-632.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.7-8
, pp. 623-632
-
-
Kizaka-Kondoh, S.1
Tanaka, S.2
Harada, H.3
-
14
-
-
43649093915
-
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
-
Kaelin WG Jr, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell. 2008;30(4):393-402.
-
(2008)
Mol Cell
, vol.30
, Issue.4
, pp. 393-402
-
-
Kaelin Jr., W.G.1
Ratcliffe, P.J.2
-
15
-
-
13944276440
-
OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha
-
Baek JH, Mahon PC, Oh J, et al. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha. Mol Cell. 2005;17(4):503-512.
-
(2005)
Mol Cell
, vol.17
, Issue.4
, pp. 503-512
-
-
Baek, J.H.1
Mahon, P.C.2
Oh, J.3
-
16
-
-
11844263980
-
Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia
-
Schnitzer SE, Schmid T, Zhou J, et al. Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia. FEBS Lett. 2005;579(2):529-533.
-
(2005)
FEBS Lett
, vol.579
, Issue.2
, pp. 529-533
-
-
Schnitzer, S.E.1
Schmid, T.2
Zhou, J.3
-
17
-
-
44449159236
-
Reactive oxygen species and HIF-1 signalling in cancer
-
Galanis A, Pappa A, Giannakakis A, et al. Reactive oxygen species and HIF-1 signalling in cancer. Cancer Lett. 2008;266(1):12-20.
-
(2008)
Cancer Lett
, vol.266
, Issue.1
, pp. 12-20
-
-
Galanis, A.1
Pappa, A.2
Giannakakis, A.3
-
18
-
-
33745631769
-
Cell signaling. H2O2, a necessary evil for cell signaling
-
Rhee SG. Cell signaling. H2O2, a necessary evil for cell signaling. Science. 2006;312(5782):1882-1883.
-
(2006)
Science
, vol.312
, Issue.5782
, pp. 1882-1883
-
-
Rhee, S.G.1
-
19
-
-
70549092785
-
Mitochondrial reactive oxygen species regulate hypoxic signaling
-
Hamanaka RB, Chandel NS. Mitochondrial reactive oxygen species regulate hypoxic signaling. Curr Opin Cell Biol. 2009;21(6):894-899.
-
(2009)
Curr Opin Cell Biol
, vol.21
, Issue.6
, pp. 894-899
-
-
Hamanaka, R.B.1
Chandel, N.S.2
-
20
-
-
70450278715
-
Reactive oxygen species-generating mitochondrial DNA mutation up-regulates HIF-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway
-
Koshikawa N, Hayashi J, Nakagawara A, et al. Reactive oxygen species-generating mitochondrial DNA mutation up-regulates HIF-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway. J Biol Chem. 2009;284(48): 33185-33194.
-
(2009)
J Biol Chem
, vol.284
, Issue.48
, pp. 33185-33194
-
-
Koshikawa, N.1
Hayashi, J.2
Nakagawara, A.3
-
21
-
-
34249309925
-
Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of HIF-1alpha and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway
-
Jin HO, An S, Lee HC, et al. Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of HIF-1alpha and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway. Cell Signal. 2007;19(7):1393-1403.
-
(2007)
Cell Signal
, vol.19
, Issue.7
, pp. 1393-1403
-
-
Jin, H.O.1
An, S.2
Lee, H.C.3
-
22
-
-
20344386238
-
Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling
-
Emerling BM, Platanias LC, Black E, et al. Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Mol Cell Biol. 2005;25(12):4853-4862.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.12
, pp. 4853-4862
-
-
Emerling, B.M.1
Platanias, L.C.2
Black, E.3
-
23
-
-
70349301394
-
Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells
-
Lee WY, Liu KW, Yeung JH. Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells. Cancer Lett. 2009;285(1):46-57.
-
(2009)
Cancer Lett
, vol.285
, Issue.1
, pp. 46-57
-
-
Lee, W.Y.1
Liu, K.W.2
Yeung, J.H.3
-
24
-
-
36749059523
-
Up-regulation of cyclooxygenase-2 by cobalt chloride-induced hypoxia is medi-ated by phospholipase D isozymes in human astroglioma cells
-
Ahn BH, Park MH, Lee YH, et al. Up-regulation of cyclooxygenase-2 by cobalt chloride-induced hypoxia is medi-ated by phospholipase D isozymes in human astroglioma cells. Biochim Biophys Acta. 2007;1773(12): 1721-1731.
-
(2007)
Biochim Biophys Acta
, vol.1773
, Issue.12
, pp. 1721-1731
-
-
Ahn, B.H.1
Park, M.H.2
Lee, Y.H.3
|