A common pathway for a rare disease?

Science

Volumn 342, Issue 6165, 2013, Pages 1453-1454

  Vafai, Scott B ^a,b,c   Mootha, Vamsi K ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; IRON SULFUR PROTEIN; LACTIC ACID; MAMMALIAN TARGET OF RAPAMYCIN; MITOCHONDRIAL DNA; PYRUVIC ACID; RAPAMYCIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MTOR PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; NEUROPROTECTIVE AGENT; TARGET OF RAPAMYCIN KINASE;

CHILD HEALTH; DISEASE INCIDENCE; DRUG; MITOCHONDRION; NUMERICAL MODEL;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; BASAL GANGLION; BRAIN DAMAGE; BRAIN MITOCHONDRION; BRAIN STEM; CHILD; CHILDHOOD MORTALITY; DEGENERATIVE DISEASE; DISEASE COURSE; ENZYME DEFICIENCY; HUMAN; INFANT; LEIGH DISEASE; LIFESPAN; MOUSE; NEUROIMAGING; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; OXIDATIVE PHOSPHORYLATION; PARKINSON DISEASE; PRIORITY JOURNAL; PUTAMEN; RARE DISEASE; SHORT SURVEY; SYMPTOM; ANIMAL; ANTAGONISTS AND INHIBITORS; MITOCHONDRIAL DISEASES; MOLECULARLY TARGETED THERAPY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG ANTAGONISM; NOTE;

ANIMALS; LEIGH DISEASE; MITOCHONDRIAL DISEASES; MOLECULAR TARGETED THERAPY; MULTIPROTEIN COMPLEXES; NEUROPROTECTIVE AGENTS; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84890809938     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1248449     Document Type: Short Survey

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