Clostridium difficile PCR ribotype 046 is common among neonatal pigs and humans in Sweden

Clinical Microbiology and Infection

Volumn 20, Issue 1, 2014, Pages

  Noren T ^a   Johansson, K ^a   Unemo, M ^a  

^a ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Clostridium difficile; Clostridium difficile infection; Human; PCR ribotype 046; Piglet

Indexed keywords

MOXIFLOXACIN;

ANTIBIOTIC RESISTANCE; BACTERIAL STRAIN; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; EPIDEMIC; FECES COMPOSITION; NOTE; PIGLET; POLYMERASE CHAIN REACTION SYSTEM; PREVALENCE; PRIORITY JOURNAL; SWEDEN; SWINE;

CLOSTRIDIUM DIFFICILE; SUIDAE;

CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; HUMAN; PCR RIBOTYPE 046; PIGLET;

ANIMALS; ANIMALS, NEWBORN; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; FECES; HUMANS; POLYMERASE CHAIN REACTION; RIBOTYPING; SWEDEN; SWINE; SWINE DISEASES; ZOONOSES;

EID: 84890804205     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/1469-0691.12296     Document Type: Article

References (24)

1. Kuijper EJ, Barbut F, Brazier JS et al. Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008. Euro Surveill 2008; 13: Pii: 18942.
2. Al Saif N, Brazier JS. The distribution of Clostridium difficile in the environment of South Wales. J Med Microbiol 1996; 45: 133-137.
3. Hopman NE, Keessen EC, Harmanus C et al. Acquisition of Clostridium difficile by piglets. Vet Microbiol 2011; 149: 186-192.
4. Hensgens MPM, Keessen EC, Squire MM et al. Clostridium difficile infection in the community: a zoonotic disease? Clin Microbiol Infect 2012; 18: 635-645.
5. Debast SB, van Leengoed LA, Goorhuis A, Harmanus C, Kuijper EJ, Bergwerff AA. Clostridium difficile PCR ribotype 078 toxinotype V found in diarrhoeal pigs identical to isolates from affected humans. Environ Microbiol 2009; 11: 505-511.
6. Songer JG. The emergence of Clostridium difficile as a pathogen of food animals. Anim Health Res Rev 2004; 5: 321-326.
7. Songer JG, Anderson MA. Clostridium difficile: an important pathogen of food animals. Anaerobe 2006; 12: 1-4.
8. Steele J, Feng H, Parry N, Tzipori S. Piglet models of acute or chronic Clostridium difficile illness. J Infect Dis 2010; 201: 428-434.
9. Alvarez-Perez S, Blanco JL, Bouza E et al. Prevalence of Clostridium difficile in diarrhoeic and non-diarrhoeic piglets. Vet Microbiol 2009; 137: 302-305.
10. Keel MK, Songer JG. The distribution and density of Clostridium difficile toxin receptors on the intestinal mucosa of neonatal pigs. Vet Pathol 2007; 44: 814-822.
11. Knight DR, Thean S, Putsathit P, Fenwick S, Riley TV. Cross-sectional study reveals high prevalence of Clostridium difficile non-PCR ribotype 078 strains in Australian veal calves at slaughter. Appl Environ Microbiol 2013; 79: 263.
12. Goorhuis A, Debast SB, van Leengoed LA et al. Clostridium difficile PCR ribotype 078: an emerging strain in humans and in pigs? J Clin Microbiol 2008; 46: 1157.
13. Båverud V. Clostridium difficile diarrhea: infection control in horses. Vet Clin North Am Equine Pract 2004; 20: 615-630.
14. Von Abercron SM, Karlsson F, Wigh GT, Wierup M, Krovacek K. Low occurrence of Clostridium difficile in retail ground meat in Sweden. J Food Prot 2009; 72: 1732-1734.
15. Åkerlund T, Alefjord I, Dohnhammar U, Struwe J, Noren T, Tegmark-Wisell K. Geographical clustering of cases of infection with moxifloxacin-resistant Clostridium difficile PCR-ribotypes 012, 017 and 046 in Sweden, 2008 and 2009. Euro Surveill 2011; 16: Pii: 19813.
16. Bauer MP, Notemans DW, van Barthems BH et al. Clostridium difficile infection in Europe: a hospital-based survey. Lancet 2011; 377: 63-73.
17. Weese JS, Avery BP, Rousseau J, Reid-Smith RJ. Detection and enumeration of Clostridium difficile spores in retail beef and pork. Appl Environ Microbiol 2009; 75: 5009-5011.
18. Noren T, Alriksson I, Åkerlund T, Burman LG, Unemo M. In vitro susceptibility to 17 antimicrobials of clinical Clostridium difficile isolates collected in 1993-2007 in Sweden. Clin Microbiol Infect 2010; 16: 1104-1110.
19. Noren T, Åkerlund T, Bäck E et al. Molecular epidemiology of hospital-associated and community-acquired Clostridium difficile infection in a Swedish county. J Clin Microbiol 2004; 42: 3635-3643.
20. Stubbs SL, Brazier JS, O'Neill GL, Duerden BI. PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J Clin Microbiol 1999; 37: 461-463.
21. Keessen EC, Gaastra W, Lipman LJ. Clostridium difficile infection in humans and animals, differences and similarities. Vet Microbiol 2011; 153: 205-217.
22. Weese JS, Wakeford T, Reid-Smith R, Rousseau J, Friendship R. Longitudinal investigation of Clostridium difficile shedding in piglets. Anaerobe 2010; 16: 501-504.
23. Grave K, Torren-Edo J, Mackay D. Comparison of the sales of veterinary antibacterial agents between 10 European countries. J Antimicrob Chemother 2010; 65: 2037-2040.
24. Stabler RA, Gerding DN, Songer JG et al. Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. J Bacteriol 2006; 188: 7297-7305.