Wnt inhibitory factor (WIF)-1 promotes melanogenesis in normal human melanocytes

Pigment Cell and Melanoma Research

Volumn 27, Issue 1, 2014, Pages 72-81

  Park, Tae Jun ^a   Kim, Misun ^a   Kim, Hyeran ^a   Park, Sun Yi ^a   Park, Kyoung Chan ^b   Ortonne, Jean Paul ^c   Kang, Hee Young ^a  

^a Ajou University School of Medicine   (South Korea)

^b Seoul National University Bundang Hospital   (South Korea)

^c CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

Author keywords

Melanocytes; Melanogenesis; Melasma; Wnt inhibitory factor 1

Indexed keywords

BETA CATENIN; LENTIVIRUS VECTOR; MELANIN; MESSENGER RNA; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT INHIBITORY FACTOR 1;

ARTICLE; CHLOASMA; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; KERATINOCYTE; MALE; MELANOCYTE; MELANOGENESIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SKIN; SKIN CELL; SKIN PIGMENTATION; UPREGULATION; WESTERN BLOTTING;

MELANOCYTES; MELANOGENESIS; MELASMA; WNT INHIBITORY FACTOR-1;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELLS, CULTURED; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; MALE; MELANOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REPRESSOR PROTEINS;

EID: 84890790586     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/pcmr.12168     Document Type: Article

References (24)

1. Bellei, B., Pitisci, A., Catricalà, C., Larue, L., and Picardo, M. (2011). Wnt/β-catenin signaling is stimulated by α-melanocyte-stimulating hormone in melanoma and melanocyte cells: implication in cell differentiation. Pigment Cell Melanoma Res. 24, 309-325.
2. Chien, A.J., Conrad, W.H., and Moon, R.T. (2009). A Wnt survival guide: from flies to human disease. J. Invest. Dermatol. 129, 1614-1627.
3. Cho, S.W., Yang, J.Y., Sun, H.J., Jung, J.Y., Her, S.J., Cho, H.Y., Choi, H.J., Kim, S.W., Kim, S.Y., and Shin, C.S. (2009). Wnt inhibitory factor (WIF)-1 inhibits osteoblastic differentiation in mouse embryonic mesenchymal cells. Bone 44, 1069-1077.
4. Chow, T.W., Ong, M.T., and Shamsuddin, S. (2013). WIF-1 might play additional role in carcinogenesis and cancer growth via EGFR signaling pathway. J. Biochem. Tech. 4, 645-647.
5. Dunn, K.J., Brady, M., Ochsenbauer-Jambor, C., Snyder, S., Incao, A., and Pavan, W.J. (2005). WNT1 and WNT3a promote expansion of melanocytes through distinct modes of action. Pigment Cell Res. 18, 167-180.
6. Fang, X., Yu, S.X., Lu, Y., Bast, R.C. Jr, Woodgett, J.R., and Mills, G.B. (2002). Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. Proc. Natl Acad. Sci. USA 97, 11960-11965.
7. Grimes, P.E., Yamada, N., and Bhawan, J. (2005). Light microscopic, immunohistochemical, and ultrastructural alterations in patients with melasma. Am. J. Dermatopathol. 27, 96-101.
8. Gudjonsson, J.E., Johnston, A., Stoll, S.W. et al. (2010). Evidence for altered Wnt signaling in psoriatic skin. J. Invest. Dermatol. 130, 1849-1859.
9. Hari, L., Brault, V., Kléber, M., Lee, H.Y., Ille, F., Leimeroth, R., Paratore, C., Suter, U., Kemler, R., and Sommer, L. (2002). Lineage-specific requirements of beta-catenin in neural crest development. J. Cell Biol. 159, 867-880.
10. Kang, H.Y., Suzuki, I., Lee, D.J., Ha, J., Reiniche, P., Aubert, J., Deret, S., Zugaj, D., Voegel, J.J., and Ortonne, J.P. (2011). Transcriptional profiling shows altered expression of wnt pathway- and lipid metabolism-related genes as well as melanogenesis-related genes in melasma. J. Invest. Dermatol. 131, 1692-1700.
11. Keil, K.P., Mehta, V., Branam, A.M., Abler, L.L., Buresh-Stiemke, R.A., Joshi, P.S., Schmitz, C.T., Marker, P.C., and Vezina, C.M. (2012). Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development. Endocrinology 153, 6091-6103.
12. Kim, J.Y., Lee, T.R., and Lee, A.Y. (2013). Reduced WIF-1 Expression Stimulates Skin Hyperpigmentation in Patients with Melasma. J. Invest. Dermatol. 133, 191-200.
13. Kress, E., Rezza, A., Nadjar, J., Samarut, J., and Plateroti, M. (2009). The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestine. J. Biol. Chem. 284, 1234-1241.
14. Luciani, F., Champeval, D., Herbette, A. et al. (2011). Biological and mathematical modeling of melanocyte development. Development 138, 3943-3954.
15. von Marschall, Z., and Fisher, L.W. (2010). Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling. Biochem. Biophys. Res. Commun. 400, 299-304.
16. Mii, Y., and Taira, M. (2009). Secreted Frizzled-related proteins enhance the diffusion of Wnt ligands and expand their signalling range. Development 136, 4083-4088.
17. Moll, I., Houdek, P., Schmidt, H., and Moll, R. (1998). Characterization of epidermal wound healing in a human skin organ culture model: acceleration by transplanted keratinocytes. J. Invest. Dermatol. 111, 251-258.
18. Novak, A., and Dedhar, S. (1999). Signaling through beta-catenin and Lef/Tcf. Cell. Mol. Life Sci. 56, 523-537.
19. Torres-Álvarez, B., Mesa-Garza, I.G., Castanedo-Cázares, J.P. et al. (2011). Histochemical and immunohistochemical study in melasma: evidence of damage in the basal membrane. Am. J. Dermatopathol. 33, 291-295.
20. Wu, J., Fang, J., Yang, Z., Chen, F., Liu, J., and Wang, Y. (2012). Wnt inhibitory factor-1 regulates glioblastoma cell cycle and proliferation. J. Clin. Neurosci. 19, 1428-1432.
21. Yamaguchi, Y., Passeron, T., Hoashi, T. et al. (2008). Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/beta-catenin signaling in keratinocytes. FASEB J. 22, 1009-1020.
22. Yamaguchi, Y., Morita, A., Maeda, A., and Hearing, V.J. (2009). Regulation of skin pigmentation and thickness by Dickkopf 1 (DKK1). J. Investig. Dermatol. Symp. Proc. 14, 73-75.
23. Yamamura, S., Kawakami, K., Hirata, H., Ueno, K., Saini, S., Majid, S., and Dahiya, R. (2010). Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer. Mol. Cancer Ther. 9, 1680-1687.
24. Yoshino, K., Rubin, J.S., Higinbotham, K.G., Uren, A., Anest, V., Plisov, S.Y., and Perantoni, A.O. (2001). Secreted Frizzled-related proteins can regulate metanephric development. Mech. Dev. 102, 45-55.