-
1
-
-
33646134826
-
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
-
Banziger C, Soldini D, Schutt C, Zipperlen P, Hausmann G, Basler K. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 2006;125:509-22.
-
(2006)
Cell
, vol.125
, pp. 509-522
-
-
Banziger, C.1
Soldini, D.2
Schutt, C.3
Zipperlen, P.4
Hausmann, G.5
Basler, K.6
-
2
-
-
33646123992
-
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
-
Bartscherer K, Pelte N, Ingelfinger D, Boutros M. Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 2006;125:523-33.
-
(2006)
Cell
, vol.125
, pp. 523-533
-
-
Bartscherer, K.1
Pelte, N.2
Ingelfinger, D.3
Boutros, M.4
-
4
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
DOI 10.1038/nature03319
-
Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005;434:843-50. (Pubitemid 40558990)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
5
-
-
49049103833
-
Wnt signaling and cancer development: Therapeutic implication
-
Paul S, Dey A. Wnt signaling and cancer development: therapeutic implication. Neoplasma 2008;55:165-76.
-
(2008)
Neoplasma
, vol.55
, pp. 165-176
-
-
Paul, S.1
Dey, A.2
-
6
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
DOI 10.1242/jcs.00623
-
Kawano Y, Kypta R. Secreted antagonists of the Wnt signalling pathway. J Cell Sci 2003;116:2627-34. (Pubitemid 36857216)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.13
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
7
-
-
0033118492
-
A new secreted protein that binds to Wnt proteins and inhibits their activites
-
DOI 10.1038/18899
-
Hsieh JC, Kodjabachian L, Rebbert ML, et al. A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature 1999;398:431-6. (Pubitemid 29180376)
-
(1999)
Nature
, vol.398
, Issue.6726
, pp. 431-436
-
-
Hsieh, J.-C.1
Kodjabachian, L.2
Rebbert, M.L.3
Rattner, A.4
Smallwood, P.M.5
Samos, C.H.6
Nusse, R.7
Dawid, I.B.8
Nathans, J.9
-
8
-
-
0030905162
-
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors
-
Rattner A, Hsieh JC, Smallwood PM, et al. A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A 1997;94:2859-63.
-
(1997)
Proc Natl Acad Sci U S a
, vol.94
, pp. 2859-2863
-
-
Rattner, A.1
Hsieh, J.C.2
Smallwood, P.M.3
-
9
-
-
4444343396
-
Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma
-
DOI 10.1038/sj.onc.1207881
-
Lee AY, He B, You L, et al. Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene 2004;23:6672-6. (Pubitemid 39265531)
-
(2004)
Oncogene
, vol.23
, Issue.39
, pp. 6672-6676
-
-
Lee, A.Y.1
He, B.2
You, L.3
Dadfarmay, S.4
Xu, Z.5
Mazieres, J.6
Mikami, I.7
McCormick, F.8
Jablons, D.M.9
-
10
-
-
34948898013
-
Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer
-
DOI 10.1038/sj.bjc.6603968, PII 6603968
-
Cheng YY, Yu J, Wong YP, et al. Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer. Br J Cancer 2007;97:895-901. (Pubitemid 47519311)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.7
, pp. 895-901
-
-
Cheng, Y.Y.1
Yu, J.2
Wong, Y.P.3
Man, E.P.S.4
To, K.F.5
Jin, V.X.6
Li, J.7
Tao, Q.8
Sung, J.J.Y.9
Chan, F.K.L.10
Leung, W.K.11
-
11
-
-
34547851719
-
Hypermethylation of SFRP2 as a potential marker for stool-based detection of colorectal cancer and precancerous lesions
-
DOI 10.1007/s10620-007-9755-y
-
Huang Z, Li L, Wang J. Hypermethylation of SFRP2 as a potential marker for stool-based detection of colorectal cancer and precancerous lesions. Dig Dis Sci 2007;52:2287-91. (Pubitemid 47246528)
-
(2007)
Digestive Diseases and Sciences
, vol.52
, Issue.9
, pp. 2287-2291
-
-
Huang, Z.1
Li, L.2
Wang, J.3
-
12
-
-
36349001733
-
SFRP2 methylation in fecal DNA - A marker for colorectal polyps
-
Oberwalder M, Zitt M, Wontner C, et al. SFRP2 methylation in fecal DNA - a marker for colorectal polyps. Int J Colorectal Dis 2008;23:15-9.
-
(2008)
Int J Colorectal Dis
, vol.23
, pp. 15-19
-
-
Oberwalder, M.1
Zitt, M.2
Wontner, C.3
-
13
-
-
40049096639
-
Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening
-
DOI 10.3748/wjg.14.524
-
Wang DR, Tang D. Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening. World J Gastroenterol 2008;14:524-31. (Pubitemid 351320817)
-
(2008)
World Journal of Gastroenterology
, vol.14
, Issue.4
, pp. 524-531
-
-
Wang, D.-R.1
Tang, D.2
-
14
-
-
58149345192
-
Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer
-
Veeck J, Noetzel E, Bektas N, et al. Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer. Mol Cancer 2008;7:83.
-
(2008)
Mol Cancer
, vol.7
, pp. 83
-
-
Veeck, J.1
Noetzel, E.2
Bektas, N.3
-
15
-
-
40849116461
-
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
-
DOI 10.1038/sj.bjc.6604259, PII 6604259
-
Suzuki H, Toyota M, Carraway H, et al. Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br J Cancer 2008;98:1147-56. (Pubitemid 351399804)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.6
, pp. 1147-1156
-
-
Suzuki, H.1
Toyota, M.2
Caraway, H.3
Gabrielson, E.4
Ohmura, T.5
Fujikane, T.6
Nishikawa, N.7
Sogabe, Y.8
Nojima, M.9
Sonoda, T.10
Mori, M.11
Hirata, K.12
Imai, K.13
Shinomura, Y.14
Baylin, S.B.15
Tokino, T.16
-
16
-
-
60749096511
-
SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway
-
Chung MT, Lai HC, Sytwu HK, et al. SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway. Gynecol Oncol 2009;112:646-53.
-
(2009)
Gynecol Oncol
, vol.112
, pp. 646-653
-
-
Chung, M.T.1
Lai, H.C.2
Sytwu, H.K.3
-
17
-
-
0034738968
-
Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells
-
Roth W, Wild-Bode C, Platten M, et al. Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells. Oncogene 2000;19:4210-20.
-
(2000)
Oncogene
, vol.19
, pp. 4210-4220
-
-
Roth, W.1
Wild-Bode, C.2
Platten, M.3
-
18
-
-
2442597995
-
Autocrine/paracrine secreted Frizzled-related protein 2 induces cellular resistance to apoptosis a possible mechanism of mammary tumorigenesis
-
Lee JL, Lin CT, Chueh LL, Chang CJ. Autocrine/paracrine secreted Frizzled-related protein 2 induces cellular resistance to apoptosis: a possible mechanism of mammary tumorigenesis. J Biol Chem 2004;279:14602-9.
-
(2004)
J Biol Chem
, vol.279
, pp. 14602-14609
-
-
Lee, J.L.1
Lin, C.T.2
Chueh, L.L.3
Chang, C.J.4
-
19
-
-
59449088654
-
The frizzled-related sFRP2 gene is a target of thyroid hormone receptor α1 and activates β-catenin signaling in mouse intestine
-
Kress E, Rezza A, Nadjar J, Samarut J, Plateroti M. The frizzled-related sFRP2 gene is a target of thyroid hormone receptor α1 and activates β-catenin signaling in mouse intestine. J Biol Chem 2009;284:1234-41.
-
(2009)
J Biol Chem
, vol.284
, pp. 1234-1241
-
-
Kress, E.1
Rezza, A.2
Nadjar, J.3
Samarut, J.4
Plateroti, M.5
-
20
-
-
0029683606
-
The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
-
Yost C, Torres M, Miller JR, Huang E, Kimelman D, Moon RT. The axisinducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev 1996;10:1443-54. (Pubitemid 26260702)
-
(1996)
Genes and Development
, vol.10
, Issue.12
, pp. 1443-1454
-
-
Yost, C.1
Torres, M.2
Miller, J.R.3
Huang, E.4
Kimelman, D.5
Moon, R.T.6
-
21
-
-
33744519452
-
Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase
-
DOI 10.1074/jbc.M508778200
-
Taurin S, Sandbo N, Qin Y, Browning D, Dulin NO. Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase. J Biol Chem 2006;281:9971-6. (Pubitemid 43864529)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.15
, pp. 9971-9976
-
-
Taurin, S.1
Sandbo, N.2
Qin, Y.3
Browning, D.4
Dulin, N.O.5
-
22
-
-
34249661591
-
Phosphorylation of β-catenin by AKT promotes β-catenin transcriptional activity
-
DOI 10.1074/jbc.M611871200
-
Fang D, Hawke D, Zheng Y, et al. Phosphorylation of β-catenin by AKT promotes β-catenin transcriptional activity. J Biol Chem 2007;282:11221-9. (Pubitemid 47100795)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.15
, pp. 11221-11229
-
-
Fang, D.1
Hawke, D.2
Zheng, Y.3
Xia, Y.4
Meisenhelder, J.5
Nika, H.6
Mills, G.B.7
Kobayashi, R.8
Hunter, T.9
Lu, Z.10
-
23
-
-
70249107457
-
FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis
-
Wang L, Sun Y, Jiang M, Zhang S, Wolfl S. FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis. Cancer Invest 2009;27:816-24.
-
(2009)
Cancer Invest
, vol.27
, pp. 816-824
-
-
Wang, L.1
Sun, Y.2
Jiang, M.3
Zhang, S.4
Wolfl, S.5
-
24
-
-
34548586570
-
Secreted frizzled related protein 2 (sFRP2) decreases susceptibility to UV-induced apoptosis in primary culture of canine mammary gland tumors by NF-κB activation or JNK suppression
-
Lee JL, Chang CJ, Chueh LL, Lin CT. Secreted frizzled related protein 2 (sFRP2) decreases susceptibility to UV-induced apoptosis in primary culture of canine mammary gland tumors by NF-κB activation or JNK suppression. Breast Cancer Res Treat 2006;100:49-58.
-
(2006)
Breast Cancer Res Treat
, vol.100
, pp. 49-58
-
-
Lee, J.L.1
Chang, C.J.2
Chueh, L.L.3
Lin, C.T.4
-
26
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden KH, Prives C. Blinded by the light: the growing complexity of p53. Cell 2009;137:413-31.
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
27
-
-
0020563501
-
Tissue and cell type-specific expression of two human c-onc genes
-
Muller R, Tremblay JM, Adamson ED, Verma IM. Tissue and cell type-specific expression of two human c-onc genes. Nature 1983;304:454-6.
-
(1983)
Nature
, vol.304
, pp. 454-456
-
-
Muller, R.1
Tremblay, J.M.2
Adamson, E.D.3
Verma, I.M.4
-
28
-
-
0037039162
-
Frizzled receptors activate a novel JNKdependent pathway that may lead to apoptosis
-
Lisovsky M, Itoh K, Sokol SY. Frizzled receptors activate a novel JNKdependent pathway that may lead to apoptosis. Curr Biol 2002;12:53-8.
-
(2002)
Curr Biol
, vol.12
, pp. 53-58
-
-
Lisovsky, M.1
Itoh, K.2
Sokol, S.Y.3
-
29
-
-
1442286330
-
The role of Bcl-2 family members in tumorigenesis
-
Kirkin V, Joos S, Zornig M. The role of Bcl-2 family members in tumorigenesis. Biochim Biophys Acta 2004;1644:229-49.
-
(2004)
Biochim Biophys Acta
, vol.1644
, pp. 229-249
-
-
Kirkin, V.1
Joos, S.2
Zornig, M.3
-
30
-
-
0036716281
-
The Bcl2 family: Regulators of the cellular life-or-death switch
-
Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2002;2:647-56.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
31
-
-
33644928489
-
BCL2 family of apoptosis-related genes: Functions and clinical implications in cancer
-
Thomadaki H, Scorilas A. BCL2 family of apoptosis-related genes: functions and clinical implications in cancer. Crit Rev Clin Lab Sci 2006;43:1-67.
-
(2006)
Crit Rev Clin Lab Sci
, vol.43
, pp. 1-67
-
-
Thomadaki, H.1
Scorilas, A.2
-
32
-
-
0024521936
-
Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to entermitosis
-
Minshull J, Blow JJ, Hunt T. Translation of cyclin mRNA is necessary for extracts of activated Xenopus eggs to entermitosis. Cell 1989;56:947-56.
-
(1989)
Cell
, vol.56
, pp. 947-956
-
-
Minshull, J.1
Blow, J.J.2
Hunt, T.3
-
33
-
-
0033870724
-
Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication
-
Soria JC, Jang SJ, Khuri FR, et al. Overexpression of cyclin B1 in early-stage non-small cell lung cancer and its clinical implication. Cancer Res 2000;60:4000-4.
-
(2000)
Cancer Res
, vol.60
, pp. 4000-4004
-
-
Soria, J.C.1
Jang, S.J.2
Khuri, F.R.3
-
34
-
-
85047698576
-
Overexpression of B-type cyclins alters chromosomal segregation
-
Sarafan-Vasseur N, Lamy A, Bourguignon J, et al. Overexpression of B-type cyclins alters chromosomal segregation. Oncogene 2002;21:2051-7.
-
(2002)
Oncogene
, vol.21
, pp. 2051-2057
-
-
Sarafan-Vasseur, N.1
Lamy, A.2
Bourguignon, J.3
-
35
-
-
33847377524
-
NF-Y-dependent cyclin B2 expression in colorectal adenocarcinoma
-
Park SH, Yu GR, Kim WH, Moon WS, Kim JH, Kim DG. NF-Y-dependent cyclin B2 expression in colorectal adenocarcinoma. Clin Cancer Res 2007;13:858-67.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 858-867
-
-
Park, S.H.1
Yu, G.R.2
Kim, W.H.3
Moon, W.S.4
Kim, J.H.5
Kim, D.G.6
-
36
-
-
18344381018
-
Cyclin e in normal and neoplastic cell cycles
-
Hwang HC, Clurman BE. Cyclin E in normal and neoplastic cell cycles. Oncogene 2005;24:2776-86.
-
(2005)
Oncogene
, vol.24
, pp. 2776-2786
-
-
Hwang, H.C.1
Clurman, B.E.2
-
37
-
-
0033575920
-
Deregulated cyclin e induces chromosome instability
-
Spruck CH, Won KA, Reed SI. Deregulated cyclin E induces chromosome instability. Nature 1999;401:297-300. (Pubitemid 129515546)
-
(1999)
Nature
, vol.401
, Issue.6750
, pp. 297-300
-
-
Spruck, C.H.1
Won, K.-A.2
Reed, S.I.3
|