MicroRNA 203 expression in keratinocytes is dependent on regulation of p53 levels by E6

Journal of Virology

Volumn 84, Issue 20, 2010, Pages 10644-10652

  McKenna, Declan J ^a   McDade, Simon S ^a   Patel, Daksha ^a   McCance, Dennis J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN PAPILLOMAVIRUS TYPE 16 ONCOPROTEIN E6; HUMAN PAPILLOMAVIRUS TYPE 16 ONCOPROTEIN E7; MICRORNA; ONCOPROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA DAMAGE; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; WESTERN BLOTTING;

BASE SEQUENCE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DNA DAMAGE; DNA PRIMERS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HOST-PATHOGEN INTERACTIONS; HUMAN PAPILLOMAVIRUS 16; HUMANS; KERATINOCYTES; MICRORNAS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS E7 PROTEINS; REPRESSOR PROTEINS; TUMOR SUPPRESSOR PROTEIN P53;

HUMAN PAPILLOMAVIRUS TYPE 16;

EID: 77957195647     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00703-10     Document Type: Article

References (49)

1. Andl, T., E. P. Murchison, F. Liu, Y. Zhang, M. Yunta-Gonzalez, J. W. Tobias, C. D. Andl, J. T. Seykora, G. J. Hannon, and S. E. Millar. 2006. The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr. Biol. 16:1041-1049.
2. Bauersachs, J., and T. Thum. 2007. MicroRNAs in the broken heart. Eur. J. Clin. Invest. 37:829-833.
3. Bernstein, E., S. Y. Kim, M. A. Carmell, E. P. Murchison, H. Alcorn, M. Z. Li, A. A. Mills, S. J. Elledge, K. V. Anderson, and G. J. Hannon. 2003. Dicer is essential for mouse development. Nat. Genet. 35:215-217.
4. Bommer, G. T., I. Gerin, Y. Feng, A. J. Kaczorowski, R. Kuick, R. E. Love, Y. Zhai, T. J. Giordano, Z. S. Qin, B. B. Moore, O. A. MacDougald, K. R. Cho, and E. R. Fearon. 2007. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr. Biol. 17:1298-1307.
5. Brosh, R., R. Shalgi, A. Liran, G. Landan, K. Korotayev, G. H. Nguyen, E. Enerly, H. Johnsen, Y. Buganim, H. Solomon, I. Goldstein, S. Madar, N. Goldfinger, A. L. Børresen-Dale, D. Ginsberg, C. C. Harris, Y. Pilpel, M. Oren, and V. Rotter. 2008. p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation. Mol. Syst. Biol. 4:229.
6. Chang, T. C., E. A. Wentzel, O. A. Kent, K. Ramachandran, M. Mullendore, K. H. Lee, G. Feldmann, M. Yamakuchi, M. Ferlito, C. J. Lowenstein, D. E. Arking, M. A. Beer, A. Maitra, and J. T. Mendell. 2007. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell 26:745-752.
7. Cowland, J. B., C. Hother, and K. Grønbaek. 2007. MicroRNAs and cancer. APMIS 115:1090-1106.
8. Dai, Y., Y. S. Huang, M. Tang, T. Y. Lv, C. X. Hu, Y. H. Tan, Z. M. Xu, and Y. B. Yin. 2007. Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus 16:939-946.
9. Dalal, S., Q. Gao, E. J. Androphy, and V. Band. 1996. Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells. J. Virol. 70:683-688. (Pubitemid 26028982)
10. Davison, T. S., C. Vagner, M. Kaghad, A. Ayed, D. Caput, and C. H. Arrowsmith. 1999. p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53. J. Biol. Chem. 274:18709-18714.
11. De Laurenzi, V., A. Rossi, A. Terrinoni, D. Barcaroli, M. Levrero, A. Costanzo, R. A. Knight, P. Guerrieri, and G. Melino. 2000. p63 and p73 transactivate differentiation gene promoters in human keratinocytes. Biochem. Biophys. Res. Commun. 273:342-346.
12. Eichten, A., M. Westfall, J. A. Pietenpol, and K. Münger. 2002. Stabilization and functional impairment of the tumor suppressor p53 by the human papillomavirus type 16 E7 oncoprotein. Virology 295:74-85.
13. Erson, A. E., and E. M. Petty. 2008. MicroRNAs in development and disease. Clin. Genet. 74:296-306.
14. Feramisco, J. D., R. L. Cayce, and H. Tsao. 2008. Recent updates on genetics: teaching old dogmas new tricks. Pediatr. Dermatol. 25:99-108.
15. Gaiddon, C., M. Lokshin, J. Ahn, T. Zhang, and C. Prives. 2001. A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol. Cell. Biol. 21:1874-1887.
16. Guess, J. C., and D. J. McCance. 2005. Decreased migration of Langerhans precursor-like cells in response to human keratinocytes expressing human papillomavirus type 16 E6/E7 is related to reduced macrophage inflammatory protein-3alpha production. J. Virol. 79:14852-14862.
17. He, L., X. He, L. P. Lim, E. de Stanchina, Z. Xuan, Y. Liang, W. Xue, L. Zender, J. Magnus, D. Ridzon, A. L. Jackson, P. S. Linsley, C. Chen, S. W. Lowe, M. A. Cleary, and G. J. Hannon. 2007. A microRNA component of the p53 tumour suppressor network. Nature 447:1130-1134.
18. Incassati, A., D. Patel, and D. J. McCance. 2006. Induction of tetraploidy through loss of p53 and upregulation of Plk1 by human papillomavirus type-16 E6. Oncogene 25:2444-2451.
19. Katoh, I., K. I. Aisaki, S. I. Kurata, S. Ikawa, and Y. Ikawa. 2000. p51A (TAp63gamma), a p53 homolog, accumulates in response to DNA damage for cell regulation. Oncogene 19:3126-3130. (Pubitemid 30438471)
20. Keyes, W. M., Y. Wu, H. Vogel, X. Guo, S. W. Lowe, and A. A. Mills. 2005. p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev. 19:1986-1999.
21. Klingelhutz, A. J., S. A. Foster, and J. K. McDougall. 1996. Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 380:79-82.
22. Knight, S. W., and B. L. Bass. 2001. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293:2269-2271.
23. Latronico, M. V., D. Catalucci, and G. Condorelli. 2007. Emerging role of microRNAs in cardiovascular biology. Circ. Res. 101:1225-1236.
24. Lee, H., and D. Kimelman. 2002. A dominant-negative form of p63 is required for epidermal proliferation in zebrafish. Dev. Cell 2:607-616. (Pubitemid 34538141)
25. Lena, A. M., R. Shalom-Feuerstein, P. Rivetti di Val Cervo, D. Aberdam, R. A. Knight, G. Melino, and E. Candi. 2008. miR-203 represses 'stemness' by repressing DeltaNp63. Cell Death Differ. 15:1187-1195.
26. Li, Y., Z. Zhou, and C. Chen. 2008. WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis. Cell Death Differ. 5:1941-1951.
27. Liu, Y., J. J. Chen, Q. Gao, S. Dalal, Y. Hong, C. P. Mansur, V. Band, and E. J. Androphy. 1999. Multiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cells. J. Virol. 73:7297-7307.
28. Loots, G., and I. Ovcharenko. 2004. rVista 2.0: evolutionary analysis of transcription factor binding sites. Nucleic Acids Res. 32:W217-W221.
29. Marchbank, A., L. J. Su, P. Walsh, J. DeGregori, K. Penheiter, T. B. Grayson, R. P. Dellavalle, and L. A. Lee. 2003. The CUSP DeltaNp63alpha isoform of human p63 is downregulated by solar-simulated ultraviolet radiation. J. Dermatol. Sci. 32:71-74.
30. McCance, D. J., R. Kopan, E. Fuchs, and L. A. Laimins. 1988. Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. Proc. Natl. Acad. Sci. U. S. A. 85:7169-7173.
31. Melar-New, M., and L. A. Laimins. 2010. Human papillomaviruses modulate expression of microRNA 203 upon epithelial differentiation to control levels of p63 proteins. J. Virol. 84:5212-5221.
32. Mills, A. A., B. Zheng, X. J. Wang, H. Vogel, D. R. Roop, and A. Bradley. 1999. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398:708-713.
33. Okada, Y., M. Osada, S. Kurata, S. Sato, K. Aisaki, Y. Kageyama, K. Kihara, Y. Ikawa, and I. Katoh. 2002. p53 gene family p51(p63)-encoded, secondary transactivator p51B(TAp63alpha) occurs without forming an immunoprecipitable complex with MDM2, but responds to genotoxic stress by accumulation. Exp. Cell Res. 276:194-200.
34. Ratovitski, E., B. Trink, and D. Sidransky. 2006. p63 and p73: teammates or adversaries? Cancer Cell 9:1-2.
35. Rinne, T., H. G. Brunner, and H. van Bokhoven. 2007. p63-associated disorders. Cell Cycle 6:262-268.
36. Rossi, M., R. I. Aqeilan, M. Neale, E. Candi, P. Salomoni, R. A. Knight, C. M. Croce, and G. Melino. 2006. The E3 ubiquitin ligase Itch controls the protein stability of p63. Proc. Natl. Acad. Sci. U. S. A. 103:12753-12758.
37. Sonkoly, E., T. Wei, P. C. Janson, A. Sääf, L. Lundeberg, M. Tengvall-Linder, G. Norstedt, H. Alenius, B. Homey, A. Scheynius, M. Ståhle, and A. Pivarcsi. 2007. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One 2:e610.
38. Sullivan, C. S., and D. Ganem. 2005. MicroRNAs and viral infection. Mol. Cell 20:3-7.
39. Suzuki, H. I., K. Yamagata, K. Sugimoto, T. Iwamoto, S. Kato, and K. Miyazono. 2009. Modulation of microRNA processing by p53. Nature 460: 529-534.
40. Tarasov, V., P. Jung, B. Verdoodt, D. Lodygin, A. Epanchintsev, A. Menssen, G. Meister, and H. Hermeking. 2007. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6:1586-1593.
41. Truong, A. B., and P. A. Khavari. 2007. Control of keratinocyte proliferation and differentiation by p63. Cell Cycle 6:295-299.
42. Truong, A. B., M. Kretz, T. W. Ridky, R. Kimmel, and P. A. Khavari. 2006. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev. 20:3185-3197.
43. Vilgelm, A., W. El-Rifai, and A. Zaika. 2008. Therapeutic prospects for p73 and p63: rising from the shadow of p53. Drug Resist. Updat. 11:152-163.
44. Visone, R., and C. M. Croce. 2009. MiRNAs and cancer. Am. J. Pathol. 174:1131-1138.
45. Westfall, M. D., A. S. Joyner, C. E. Barbieri, M. Livingstone, and J. A. Pietenpol. 2005. Ultraviolet radiation induces phosphorylation and ubiquitin- mediated degradation of DeltaNp63alpha. Cell Cycle 4:710-716.
46. Yang, A., M. Kaghad, Y. Wang, E. Gillett, M. D. Fleming, V. Dötsch, N. C. Andrews, D. Caput, and F. McKeon. 1998. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant- negative activities. Mol. Cell 2:305-316.
47. Yang, A., R. Schweitzer, D. Sun, M. Kaghad, N. Walker, R. T. Bronson, C. Tabin, A. Sharpe, D. Caput, C. Crum, and F. McKeon. 1999. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398:714-718.
48. Yi, R., D. O'Carroll, H. A. Pasolli, Z. Zhang, F. S. Dietrich, A. Tarakhovsky, and E. Fuchs. 2006. Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat. Genet. 38:356-362.
49. Yi, R., M. N. Poy, M. Stoffel, and E. Fuchs. 2008. A skin microRNA promotes differentiation by repressing 'stemness'. Nature 452:225-229.