Hepatitis C virus modulates lipid regulatory factor Angiopoietin-like 3 gene expression by repressing HNF-1α activity

Journal of Hepatology

Volumn 60, Issue 1, 2014, Pages 30-38

  Foka, Pelagia ^a   Karamichali, Eirini ^a   Dalagiorgou, Georgia ^a   Serti, Elisavet ^a   Doumba, Polyxeni P ^b   Pissas, George ^a   Kakkanas, Athanassios ^a   Kazazi, Dorothea ^a   Kochlios, Emmanouil ^a   Gaitanou, Maria ^a   Koskinas, John ^b   Georgopoulou, Urania ^a   Mavromara, Penelope ^a  

^a HELLENIC PASTEUR INSTITUTE   (Greece)

^b HIPPOKRATION HOSPITAL   (Greece)

Author keywords

Core; HCV infection; Lipid metabolism; Phosphorylation; Transcriptional regulation

Indexed keywords

ANGIOPOIETIN; ANGIOPOIETIN LIKE 3; DYRK1B PROTEIN; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; LUCIFERASE; MESSENGER RNA; PROTEIN; PROTEIN P16; PROTEIN P21; PROTEIN P23; UNCLASSIFIED DRUG; CIS ACTING ELEMENT; PROTEIN INHIBITOR;

ADULT; AGED; ARTICLE; BINDING AFFINITY; CELL FRACTIONATION; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEPATITIS C VIRUS; HUMAN; IMMUNOFLUORESCENCE; LIPID BLOOD LEVEL; LIPID METABOLISM; LIPOGENESIS; MALE; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; VIRUS CORE; VIRUS REPLICATION; WESTERN BLOTTING; CELL MIGRATION; DNA BINDING; GENE MUTATION; GENETIC TRANSFECTION; HEPATITIS C; HUMAN CELL; HUMAN TISSUE; LIVER CELL; PROTEIN INTERACTION;

ANGIOPOIETIN-LIKE 3; ANGPTL-3; APOE; APOLIPOPROTEIN E; CHIP; CHROMATIN IMMUNOPRECIPITATION; CORE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ELISA; EMSA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HCV; HCV INFECTION; HDL; HEPATIC LIPASE; HEPATIC NUCLEAR FACTOR-1Α; HEPATITIS C VIRUS; HIGH DENSITY LIPOPROTEIN; HL; HNF-1Α; LDL; LIPID METABOLISM; LIPOPROTEIN LIPASE; LIVER-X RECEPTOR; LOW DENSITY LIPOPROTEIN; LPL; LXR; MINIBRAIN RELATED KINASE/DUAL-SPECIFICITY YAK RELATED KINASE 1B; MIRK/DYRK1B; NASH; NON-ALCOHOLIC STEATOHEPATITIS; OPEN READING FRAME; ORF; PEROXISOME PROLIFARATOR-ACTIVATED RECEPTOR Β; PHOSPHOINOSITIDE-3-KINASE; PHOSPHORYLATION; PI3K; PPARΒ; QRT-PCR; QUANTITATIVE REVERSE-TRANSCRIPTION POLYMERASE CHAIN REACTION; RELATIVE LUCIFERASE ACTIVITY; RETINOIC-X RECEPTOR; RLA; RXR; SREBP1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTIONAL REGULATION; VERY LOW DENSITY LIPOPROTEIN; VLDL;

ADULT; ANGIOPOIETINS; DNA; DOWN-REGULATION; FEMALE; HEPACIVIRUS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; MIDDLE AGED; ORPHAN NUCLEAR RECEPTORS; PROMOTER REGIONS, GENETIC; RETINOID X RECEPTORS;

EID: 84890568217     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.08.016     Document Type: Article

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