-
1
-
-
64549158960
-
Hepatic nuclear factor 1-alpha: inflammation, genetics, and atherosclerosis
-
Armendariz AD, Krauss RM. 2009. Hepatic nuclear factor 1-alpha: inflammation, genetics, and atherosclerosis. Curr. Opin. Lipidol. 20:106-111.
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 106-111
-
-
Armendariz, A.D.1
Krauss, R.M.2
-
2
-
-
0036312080
-
Hepatocyte nuclear factor-1α recruits the transcriptional co-activator p300 on the GLUT2 gene promoter
-
Ban N, et al. 2002. Hepatocyte nuclear factor-1α recruits the transcriptional co-activator p300 on the GLUT2 gene promoter. Diabetes 51:1409-1418.
-
(2002)
Diabetes
, vol.51
, pp. 1409-1418
-
-
Ban, N.1
-
3
-
-
0034623816
-
Efficient initiation of HCV RNA replication in cell culture
-
Blight KJ, Kolykhalov AA, Rice CM. 2000. Efficient initiation of HCV RNA replication in cell culture. Science 290:1972-1974.
-
(2000)
Science
, vol.290
, pp. 1972-1974
-
-
Blight, K.J.1
Kolykhalov, A.A.2
Rice, C.M.3
-
4
-
-
0036893332
-
Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication
-
Blight KJ, McKeating JA, Rice CM. 2002. Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J. Virol. 76: 13001-13014.
-
(2002)
J. Virol.
, vol.76
, pp. 13001-13014
-
-
Blight, K.J.1
McKeating, J.A.2
Rice, C.M.3
-
5
-
-
18644363653
-
Bi- allelic inactivation of TCF1 in hepatic adenomas
-
Bluteau O, et al. 2002. Bi-allelic inactivation of TCF1 in hepatic adenomas. Nat. Genet. 32:312-315.
-
(2002)
Nat. Genet.
, vol.32
, pp. 312-315
-
-
Bluteau, O.1
-
6
-
-
67849133617
-
Efficient production of infectious hepatitis C virus with adaptive mutations in cultured hepatoma cells
-
Bungyoku Y, et al. 2009. Efficient production of infectious hepatitis C virus with adaptive mutations in cultured hepatoma cells. J. Gen. Virol. 90:1681-1691.
-
(2009)
J. Gen. Virol.
, vol.90
, pp. 1681-1691
-
-
Bungyoku, Y.1
-
7
-
-
0034674711
-
Identification of transacting factors responsible for the tissue-specific expression of human glucose transporter type 2 isoform gene Cooperative role of hepatocyte nuclear factors 1α and 3α
-
Cha JY, Kim H, Kim KS, Hur MW, Ahn Y. 2000. Identification of transacting factors responsible for the tissue-specific expression of human glucose transporter type 2 isoform gene. Cooperative role of hepatocyte nuclear factors 1α and 3α. J. Biol. Chem. 275:18358-18365.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18358-18365
-
-
Cha, J.Y.1
Kim, H.2
Kim, K.S.3
Hur, M.W.4
Ahn, Y.5
-
8
-
-
80053592700
-
Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic
-
Denamur S, et al. 2011. Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic. Free Radic. Biol. Med. 51:1656-1665.
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 1656-1665
-
-
Denamur, S.1
-
9
-
-
55249099620
-
Hepatitis C virus infection induces apoptosis through a Bax-triggered, mitochondrion-mediated, caspase 3-dependent pathway
-
Deng L, et al. 2008. Hepatitis C virus infection induces apoptosis through a Bax-triggered, mitochondrion-mediated, caspase 3-dependent pathway. J. Virol. 82:10375-10385.
-
(2008)
J. Virol.
, vol.82
, pp. 10375-10385
-
-
Deng, L.1
-
10
-
-
33744791738
-
NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequencedependent manner
-
Deng L, et al. 2006. NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequencedependent manner. J. Gen. Virol. 87:1703-1713.
-
(2006)
J. Gen. Virol.
, vol.87
, pp. 1703-1713
-
-
Deng, L.1
-
11
-
-
80052290588
-
Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated FoxO1-dependent pathway
-
Deng L, et al. 2011. Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway. J. Virol. 85:8556-8568.
-
(2011)
J. Virol.
, vol.85
, pp. 8556-8568
-
-
Deng, L.1
-
12
-
-
34250822281
-
Chaperone-mediated autophagy
-
Dice JF. 2007. Chaperone-mediated autophagy. Autophagy 3:295-299.
-
(2007)
Autophagy
, vol.3
, pp. 295-299
-
-
Dice, J.F.1
-
13
-
-
64549142339
-
Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes
-
Dionisio N, et al. 2009. Hepatitis C virus NS5A and core proteins induce oxidative stress-mediated calcium signalling alterations in hepatocytes. J. Hepatol. 50:872-882.
-
(2009)
J. Hepatol.
, vol.50
, pp. 872-882
-
-
Dionisio, N.1
-
14
-
-
80052166468
-
Impact of the autophagy machinery on hepatitis C virus infection
-
Dreux M, Chisari FV. 2011. Impact of the autophagy machinery on hepatitis C virus infection. Viruses 3:1342-1357.
-
(2011)
Viruses
, vol.3
, pp. 1342-1357
-
-
Dreux, M.1
Chisari, F.V.2
-
15
-
-
29744467205
-
Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes
-
Griffin S, Clarke D, McCormick C, Rowlands D, Harris M. 2005. Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes. J. Virol. 79:15525-15536.
-
(2005)
J. Virol.
, vol.79
, pp. 15525-15536
-
-
Griffin, S.1
Clarke, D.2
McCormick, C.3
Rowlands, D.4
Harris, M.5
-
16
-
-
84455204716
-
HCV NS5A: a multifunctional regulator of cellular pathways and virus replication
-
Tan SL (ed), Horizon Bioscience, Norfolk, United Kingdom
-
He Y, Staschke KA, Tan SL. 2006. HCV NS5A: a multifunctional regulator of cellular pathways and virus replication. In Tan SL (ed), HepatitisC viruses: genomes and molecular biology. Horizon Bioscience, Norfolk, United Kingdom. http://www.ncbi.nlm.nih.gov/books/NBK1621/.
-
(2006)
HepatitisC viruses: genomes and molecular biology
-
-
He, Y.1
Staschke, K.A.2
Tan, S.L.3
-
17
-
-
16244394753
-
Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system
-
Ikeda M, et al. 2005. Efficient replication of a full-length hepatitis C virus genome, strain O, in cell culture, and development of a luciferase reporter system. Biochem. Biophys. Res. Commun. 329:1350-1359.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.329
, pp. 1350-1359
-
-
Ikeda, M.1
-
18
-
-
44649194072
-
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk
-
Inubushi S, et al. 2008. Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk. J. Gen. Virol. 89:1231-1242.
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 1231-1242
-
-
Inubushi, S.1
-
19
-
-
64549151555
-
HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters
-
Kasai D, et al. 2009. HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters. J. Hepatol. 50:883-894.
-
(2009)
J. Hepatol.
, vol.50
, pp. 883-894
-
-
Kasai, D.1
-
20
-
-
0031944313
-
Laron dwarfism and non-insulindependent diabetes mellitus in the Hnf-1α knockout mouse
-
Lee YH, Sauer B, Gonzalez FJ. 1998. Laron dwarfism and non-insulindependent diabetes mellitus in the Hnf-1α knockout mouse. Mol. Cell Biol. 18:3059-3068.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 3059-3068
-
-
Lee, Y.H.1
Sauer, B.2
Gonzalez, F.J.3
-
21
-
-
34547094367
-
Hepatitis C virus
-
Knipe DM, et al (ed), 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA
-
Lemon SM, Walker C, Alter MJ, Yi M. 2007. Hepatitis C virus, p 1291-1304. In Knipe DM, et al (ed), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
-
(2007)
Fields virology
, pp. 1291-1304
-
-
Lemon, S.M.1
Walker, C.2
Alter, M.J.3
Yi, M.4
-
22
-
-
80054087824
-
Mitochondrial ROS generation for regulation of autophagic pathways in cancer
-
Li ZY, Yang Y, Ming M, Liu B. 2011. Mitochondrial ROS generation for regulation of autophagic pathways in cancer. Biochem. Biophys. Res. Commun. 414:5-8.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.414
, pp. 5-8
-
-
Li, Z.Y.1
Yang, Y.2
Ming, M.3
Liu, B.4
-
23
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach BD, et al. 2005. Complete replication of hepatitis C virus in cell culture. Science 309:623-626.
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
-
24
-
-
12944262229
-
Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
-
Macheda ML, Rogers S, Best JD. 2005. Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J. Cell Physiol. 202: 654-662.
-
(2005)
J. Cell Physiol.
, vol.202
, pp. 654-662
-
-
Macheda, M.L.1
Rogers, S.2
Best, J.D.3
-
25
-
-
47949112573
-
Monogenic diabetes: implications for therapy of rare types of disease
-
Malecki MT, Mlynarski W. 2008. Monogenic diabetes: implications for therapy of rare types of disease. Diabetes Obes. Metab. 10:607-616.
-
(2008)
Diabetes Obes. Metab.
, vol.10
, pp. 607-616
-
-
Malecki, M.T.1
Mlynarski, W.2
-
26
-
-
0033025254
-
Association of diabetes mellitus and chronic hepatitis C virus infection
-
Mason AL, et al. 1999. Association of diabetes mellitus and chronic hepatitis C virus infection. Hepatology 29:328-333.
-
(1999)
Hepatology
, vol.29
, pp. 328-333
-
-
Mason, A.L.1
-
27
-
-
33746281707
-
Production of infectious hepatitis C virus particles in three-dimensional cultures of the cell line carrying the genomelength dicistronic viral RNA of genotype 1b
-
Murakami K, et al. 2006. Production of infectious hepatitis C virus particles in three-dimensional cultures of the cell line carrying the genomelength dicistronic viral RNA of genotype 1b. Virology 351:381-392.
-
(2006)
Virology
, vol.351
, pp. 381-392
-
-
Murakami, K.1
-
28
-
-
81155123213
-
Inhibition of hepatitis C virus replication through adenosine monophosphateactivated protein kinase-dependent and -independent pathways
-
Nakashima K, Takeuchi K, Chihara K, Hotta H, Sada K. 2011. Inhibition of hepatitis C virus replication through adenosine monophosphateactivated protein kinase-dependent and -independent pathways. Microbiol. Immunol. 55:774-782.
-
(2011)
Microbiol. Immunol.
, vol.55
, pp. 774-782
-
-
Nakashima, K.1
Takeuchi, K.2
Chihara, K.3
Hotta, H.4
Sada, K.5
-
29
-
-
79956358281
-
Mechanisms of hepatitis C virus-related insulin resistance
-
Negro F. 2011. Mechanisms of hepatitis C virus-related insulin resistance. Clin. Res. Hepatol Gastroenterol. 35:358-363.
-
(2011)
Clin. Res. Hepatol Gastroenterol.
, vol.35
, pp. 358-363
-
-
Negro, F.1
-
30
-
-
64549126864
-
Hepatitis C virus and type 2 diabetes
-
Negro F, Alaei M. 2009. Hepatitis C virus and type 2 diabetes. World J. Gastroenterol. 15:1537-1547.
-
(2009)
World J. Gastroenterol.
, vol.15
, pp. 1537-1547
-
-
Negro, F.1
Alaei, M.2
-
31
-
-
0030031453
-
Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome
-
Pontoglio M, et al. 1996. Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome. Cell 84:575-585.
-
(1996)
Cell
, vol.84
, pp. 575-585
-
-
Pontoglio, M.1
-
32
-
-
1642464020
-
Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitisCvirus replication: role of JNK, p38 MAPK and AP-1
-
Qadri I, et al. 2004. Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitisCvirus replication: role of JNK, p38 MAPK and AP-1. Biochem. J. 378:919-928.
-
(2004)
Biochem. J.
, vol.378
, pp. 919-928
-
-
Qadri, I.1
-
33
-
-
33846483634
-
E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein
-
Shirakura M, et al. 2007. E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein. J. Virol. 81:1174-1185.
-
(2007)
J. Virol.
, vol.81
, pp. 1174-1185
-
-
Shirakura, M.1
-
34
-
-
0027155403
-
Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene
-
Takeda J, Kayano T, Fukomoto H, Bell GI. 1993. Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene. Diabetes 42:773-777.
-
(1993)
Diabetes
, vol.42
, pp. 773-777
-
-
Takeda, J.1
Kayano, T.2
Fukomoto, H.3
Bell, G.I.4
-
36
-
-
19644393931
-
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
-
Tellinghuisen TL, Marcotrigiano J, Rice CM. 2005. Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature 435:374-379.
-
(2005)
Nature
, vol.435
, pp. 374-379
-
-
Tellinghuisen, T.L.1
Marcotrigiano, J.2
Rice, C.M.3
-
37
-
-
22544470874
-
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
-
Wakita T, et al. 2005. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat. Med. 11:791-796.
-
(2005)
Nat. Med.
, vol.11
, pp. 791-796
-
-
Wakita, T.1
-
38
-
-
70349095986
-
Non- structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice
-
Wang AG, et al. 2009. Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice. J. Pathol. 219:253-262.
-
(2009)
J. Pathol.
, vol.219
, pp. 253-262
-
-
Wang, A.G.1
-
39
-
-
0032538883
-
Dominantnegative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line
-
Wang H, Maechler P, Hagenfeldt KA, Wollheim CB. 1998. Dominantnegative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line. EMBO J. 17:6701-6713.
-
(1998)
EMBO J
, vol.17
, pp. 6701-6713
-
-
Wang, H.1
Maechler, P.2
Hagenfeldt, K.A.3
Wollheim, C.B.4
-
40
-
-
10544249874
-
Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)
-
Yamagata K, et al. 1996. Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3). Nature 384:455-458.
-
(1996)
Nature
, vol.384
, pp. 455-458
-
-
Yamagata, K.1
|