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Volumn 27, Issue 12, 2013, Pages 1770-1775

Neuroprotective effects of formononetin against NMDA-induced apoptosis in cortical neurons

Author keywords

apoptosis; formononetin; isoflavone; N methyl D asparate

Indexed keywords

CASPASE 3; FORMONONETIN; N METHYL DEXTRO ASPARTIC ACID; PROCASPASE 3; PROTEIN BAX; PROTEIN BCL 2;

EID: 84890562519     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4928     Document Type: Article
Times cited : (52)

References (40)
  • 3
    • 0037213368 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
    • Borner C,. 2003. The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol Immunol 39: 615-647.
    • (2003) Mol Immunol , vol.39 , pp. 615-647
    • Borner, C.1
  • 4
    • 0029614765 scopus 로고
    • Neural apoptosis
    • Bredesen DE,. 1995. Neural apoptosis. Ann Neurol 38: 839-851.
    • (1995) Ann Neurol , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 5
    • 0027226219 scopus 로고
    • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
    • Brewer GJ, Torricelli JR, Evege EK, Price PJ,. 1993. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res 35: 567-576.
    • (1993) J Neurosci Res , vol.35 , pp. 567-576
    • Brewer, G.J.1    Torricelli, J.R.2    Evege, E.K.3    Price, P.J.4
  • 6
    • 55349109231 scopus 로고    scopus 로고
    • Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats
    • Chen X, Liu J, Gu X, Ding F,. 2008. Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats. Brain Res 1238: 189-198.
    • (2008) Brain Res , vol.1238 , pp. 189-198
    • Chen, X.1    Liu, J.2    Gu, X.3    Ding, F.4
  • 7
    • 34247131825 scopus 로고    scopus 로고
    • Neuroprotective effects of tetramethylpyrazine on hydrogen peroxide-induced apoptosis in PC12 cells
    • Cheng XR, Zhang L, Hu JJ, Sun L, Du GH,. 2007. Neuroprotective effects of tetramethylpyrazine on hydrogen peroxide-induced apoptosis in PC12 cells. Cell Biol Int 31: 438-443.
    • (2007) Cell Biol Int , vol.31 , pp. 438-443
    • Cheng, X.R.1    Zhang, L.2    Hu, J.J.3    Sun, L.4    Du, G.H.5
  • 8
    • 0032967382 scopus 로고    scopus 로고
    • The role of excitotoxicity in neurodegenerative disease: Implications for therapy
    • Doble A,. 1999. The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol Ther 81: 163-221.
    • (1999) Pharmacol Ther , vol.81 , pp. 163-221
    • Doble, A.1
  • 9
    • 67349252376 scopus 로고    scopus 로고
    • Apoptosis and the receptor specificity of its mechanisms during the neurotoxic action of glutamate
    • Evstratova AA, Mironova EV, Dvoretskova EA, Antonov SM,. 2009. Apoptosis and the receptor specificity of its mechanisms during the neurotoxic action of glutamate. Neurosci Behav Physiol 39: 353-362.
    • (2009) Neurosci Behav Physiol , vol.39 , pp. 353-362
    • Evstratova, A.A.1    Mironova, E.V.2    Dvoretskova, E.A.3    Antonov, S.M.4
  • 10
    • 0029001403 scopus 로고
    • Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain
    • Gillardon F, Wickert H, Zimmermann M,. 1995. Up-regulation of bax and down-regulation of bcl-2 is associated with kainate-induced apoptosis in mouse brain. Neurosci Lett 192: 85-88.
    • (1995) Neurosci Lett , vol.192 , pp. 85-88
    • Gillardon, F.1    Wickert, H.2    Zimmermann, M.3
  • 11
    • 65849509914 scopus 로고    scopus 로고
    • Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly
    • Gu B, Nakamichi N, Zhang WS, et al,. 2009. Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly. J Neurosci Res 87: 2145-2156.
    • (2009) J Neurosci Res , vol.87 , pp. 2145-2156
    • Gu, B.1    Nakamichi, N.2    Zhang, W.S.3
  • 12
    • 0037301661 scopus 로고    scopus 로고
    • The Yin and Yang of NMDA receptor signaling
    • Hardingham GE, Bading H,. 2003. The Yin and Yang of NMDA receptor signaling. Trends Neurosci 26: 81-89.
    • (2003) Trends Neurosci , vol.26 , pp. 81-89
    • Hardingham, G.E.1    Bading, H.2
  • 13
    • 0037636423 scopus 로고    scopus 로고
    • Identification of CYP1A2 as the main isoform for the phase i hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones
    • Hu M, Krausz K, Chen J, et al,. 2003. Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones. Drug Metab Dispos 31: 924-931.
    • (2003) Drug Metab Dispos , vol.31 , pp. 924-931
    • Hu, M.1    Krausz, K.2    Chen, J.3
  • 14
    • 0029565945 scopus 로고
    • Excitotoxicity and neurodegenerative diseases
    • Ikonomidou C, Turski L,. 1995. Excitotoxicity and neurodegenerative diseases. Curr Opin Neurol 8: 487-497.
    • (1995) Curr Opin Neurol , vol.8 , pp. 487-497
    • Ikonomidou, C.1    Turski, L.2
  • 15
    • 0242573273 scopus 로고    scopus 로고
    • The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1
    • Krapivinsky G, Krapivinsky L, Manasian Y, et al,. 2003. The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1. Neuron 40: 775-784.
    • (2003) Neuron , vol.40 , pp. 775-784
    • Krapivinsky, G.1    Krapivinsky, L.2    Manasian, Y.3
  • 17
    • 80052083256 scopus 로고    scopus 로고
    • Neuroprotective effects of estrogen against oxidative toxicity through activation of GPR30 receptor
    • doi: 10.1111/j.1440-1681.2011.05549.x.
    • Liu SB, Han J, Zhang N, Tian Z, Li XB, Zhao MG,. 2011. Neuroprotective effects of estrogen against oxidative toxicity through activation of GPR30 receptor. Clin Exp Pharmacol Physiol, doi: 10.1111/j.1440-1681.2011.05549.x.
    • (2011) Clin Exp Pharmacol Physiol
    • Liu, S.B.1    Han, J.2    Zhang, N.3    Tian, Z.4    Li, X.B.5    Zhao, M.G.6
  • 18
    • 84859299181 scopus 로고    scopus 로고
    • G-protein-coupled receptor 30 mediates rapid neuroprotective effects of estrogen via depression of NR2B-containing NMDA receptors
    • Liu SB, Zhang N, Guo YY, et al,. 2012. G-protein-coupled receptor 30 mediates rapid neuroprotective effects of estrogen via depression of NR2B-containing NMDA receptors. J Neurosci 32: 4887-4900.
    • (2012) J Neurosci , vol.32 , pp. 4887-4900
    • Liu, S.B.1    Zhang, N.2    Guo, Y.Y.3
  • 19
    • 33947331063 scopus 로고    scopus 로고
    • NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
    • Liu Y, Wong TP, Aarts M, et al,. 2007. NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J Neurosci 27: 2846-2857.
    • (2007) J Neurosci , vol.27 , pp. 2846-2857
    • Liu, Y.1    Wong, T.P.2    Aarts, M.3
  • 20
    • 0034110889 scopus 로고    scopus 로고
    • Endothelium-dependent relaxation of rat aorta and main pulmonary artery by the phytoestrogens genistein and daidzein
    • Mishra SK, Abbot SE, Choudhury Z, et al,. 2000. Endothelium-dependent relaxation of rat aorta and main pulmonary artery by the phytoestrogens genistein and daidzein. Cardiovasc Res 46: 539-546.
    • (2000) Cardiovasc Res , vol.46 , pp. 539-546
    • Mishra, S.K.1    Abbot, S.E.2    Choudhury, Z.3
  • 21
    • 62549107554 scopus 로고    scopus 로고
    • Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover)
    • Mu H, Bai YH, Wang ST, Zhu ZM, Zhang YW,. 2009. Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover). Phytomedicine 16: 314-319.
    • (2009) Phytomedicine , vol.16 , pp. 314-319
    • Mu, H.1    Bai, Y.H.2    Wang, S.T.3    Zhu, Z.M.4    Zhang, Y.W.5
  • 22
    • 21044431892 scopus 로고    scopus 로고
    • Contribution of mitogen-activated protein kinases to NMDA-induced neurotoxicity in the rat retina
    • Munemasa Y, Ohtani-Kaneko R, Kitaoka Y, et al,. 2005. Contribution of mitogen-activated protein kinases to NMDA-induced neurotoxicity in the rat retina. Brain Res 1044: 227-240.
    • (2005) Brain Res , vol.1044 , pp. 227-240
    • Munemasa, Y.1    Ohtani-Kaneko, R.2    Kitaoka, Y.3
  • 23
    • 0029068871 scopus 로고
    • Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
    • Nicholson DW, Ali A, Thornberry NA, et al,. 1995. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376: 37-43.
    • (1995) Nature , vol.376 , pp. 37-43
    • Nicholson, D.W.1    Ali, A.2    Thornberry, N.A.3
  • 24
    • 59449108594 scopus 로고    scopus 로고
    • The isoflavones mixture from Trifolium pratense L. Protects HCN 1-A neurons from oxidative stress
    • Occhiuto F, Palumbo DR, Samperi S, et al,. 2009. The isoflavones mixture from Trifolium pratense L. protects HCN 1-A neurons from oxidative stress. Phytother Res 23: 192-196.
    • (2009) Phytother Res , vol.23 , pp. 192-196
    • Occhiuto, F.1    Palumbo, D.R.2    Samperi, S.3
  • 25
    • 0034320568 scopus 로고    scopus 로고
    • Mechanisms of apoptosis
    • Reed JC,. 2000. Mechanisms of apoptosis. Am J Pathol 157: 1415-1430.
    • (2000) Am J Pathol , vol.157 , pp. 1415-1430
    • Reed, J.C.1
  • 26
    • 54549111959 scopus 로고    scopus 로고
    • The protective effects of Achyranthes bidentata polypeptides against NMDA-induced cell apoptosis in cultured hippocampal neurons through differential modulation of NR2A- and NR2B-containing NMDA receptors
    • Shen H, Yuan Y, Ding F, Liu J, Gu X,. 2008. The protective effects of Achyranthes bidentata polypeptides against NMDA-induced cell apoptosis in cultured hippocampal neurons through differential modulation of NR2A- and NR2B-containing NMDA receptors. Brain Res Bull 77: 274-281.
    • (2008) Brain Res Bull , vol.77 , pp. 274-281
    • Shen, H.1    Yuan, Y.2    Ding, F.3    Liu, J.4    Gu, X.5
  • 27
    • 84861461188 scopus 로고    scopus 로고
    • Neuroprotective effects of Salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro
    • Shi TY, Feng SF, Xing JH, et al,. 2012. Neuroprotective effects of Salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro. Neurotox Res 21: 358-367.
    • (2012) Neurotox Res , vol.21 , pp. 358-367
    • Shi, T.Y.1    Feng, S.F.2    Xing, J.H.3
  • 28
    • 0017261006 scopus 로고
    • Hypolipidemic principles of Cicer arietinum: Biochanin-A and formononetin
    • Siddiqui MT, Siddiqi M,. 1976. Hypolipidemic principles of Cicer arietinum: biochanin-A and formononetin. Lipids 11: 243-246.
    • (1976) Lipids , vol.11 , pp. 243-246
    • Siddiqui, M.T.1    Siddiqi, M.2
  • 29
    • 3543029896 scopus 로고    scopus 로고
    • The soy isoflavone, genistein, protects human cortical neuronal cells from oxidative stress
    • Sonee M, Sum T, Wang C, Mukherjee SK,. 2004. The soy isoflavone, genistein, protects human cortical neuronal cells from oxidative stress. Neurotoxicology 25: 885-891.
    • (2004) Neurotoxicology , vol.25 , pp. 885-891
    • Sonee, M.1    Sum, T.2    Wang, C.3    Mukherjee, S.K.4
  • 30
    • 33646551731 scopus 로고    scopus 로고
    • Minocycline protects PC12 cells against NMDA-induced injury via inhibiting 5-lipoxygenase activation
    • Song Y, Wei EQ, Zhang WP, et al,. 2006. Minocycline protects PC12 cells against NMDA-induced injury via inhibiting 5-lipoxygenase activation. Brain Res 1085: 57-67.
    • (2006) Brain Res , vol.1085 , pp. 57-67
    • Song, Y.1    Wei, E.Q.2    Zhang, W.P.3
  • 31
    • 0031738018 scopus 로고    scopus 로고
    • Phytoestrogens act as estrogen agonists in an estrogen-responsive pituitary cell line
    • Stahl S, Chun TY, Gray WG,. 1998. Phytoestrogens act as estrogen agonists in an estrogen-responsive pituitary cell line. Toxicol Appl Pharmacol 152: 41-48.
    • (1998) Toxicol Appl Pharmacol , vol.152 , pp. 41-48
    • Stahl, S.1    Chun, T.Y.2    Gray, W.G.3
  • 32
    • 15144345497 scopus 로고    scopus 로고
    • Pro-caspase-3 is a major physiologic target of caspase-8
    • Stennicke HR, Jurgensmeier JM, Shin H, et al,. 1998. Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem 273: 27084-27090.
    • (1998) J Biol Chem , vol.273 , pp. 27084-27090
    • Stennicke, H.R.1    Jurgensmeier, J.M.2    Shin, H.3
  • 33
    • 84863291336 scopus 로고    scopus 로고
    • Formononetin protects neurons against hypoxia-induced cytotoxicity through upregulation of ADAM10 and sAbetaPPalpha
    • Sun M, Zhou T, Zhou L, et al,. 2012. Formononetin protects neurons against hypoxia-induced cytotoxicity through upregulation of ADAM10 and sAbetaPPalpha. J Alzheimers Dis 28: 795-808.
    • (2012) J Alzheimers Dis , vol.28 , pp. 795-808
    • Sun, M.1    Zhou, T.2    Zhou, L.3
  • 34
    • 84866891041 scopus 로고    scopus 로고
    • Formononetin Attenuates IL-1β-Induced Apoptosis and NF-κB Activation in INS-1 Cells
    • Wang Y, Zhu Y, Gao L, et al,. 2012. Formononetin Attenuates IL-1β-Induced Apoptosis and NF-κB Activation in INS-1 Cells. Molecules 17: 10052-10064.
    • (2012) Molecules , vol.17 , pp. 10052-10064
    • Wang, Y.1    Zhu, Y.2    Gao, L.3
  • 35
    • 77953812949 scopus 로고    scopus 로고
    • Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways
    • Wu JH, Li Q, Wu MY, et al,. 2010. Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways. J Nutr Biochem 21: 613-620.
    • (2010) J Nutr Biochem , vol.21 , pp. 613-620
    • Wu, J.H.1    Li, Q.2    Wu, M.Y.3
  • 36
    • 77957841900 scopus 로고    scopus 로고
    • Neuroprotective effects of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors
    • Yang Q, Yang ZF, Liu SB, et al,. 2010. Neuroprotective effects of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors. Neurochem Res 35: 1353-1360.
    • (2010) Neurochem Res , vol.35 , pp. 1353-1360
    • Yang, Q.1    Yang, Z.F.2    Liu, S.B.3
  • 37
    • 14844331823 scopus 로고    scopus 로고
    • Isoflavonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate
    • Yu D, Duan Y, Bao Y, Wei C, An L,. 2005. Isoflavonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate. J Ethnopharmacol 98: 89-94.
    • (2005) J Ethnopharmacol , vol.98 , pp. 89-94
    • Yu, D.1    Duan, Y.2    Bao, Y.3    Wei, C.4    An, L.5
  • 38
    • 65349187738 scopus 로고    scopus 로고
    • Protection of PC12 cells against superoxide-induced damage by isoflavonoids from Astragalus mongholicus
    • Yu DH, Bao YM, An LJ, Yang M,. 2009. Protection of PC12 cells against superoxide-induced damage by isoflavonoids from Astragalus mongholicus. Biomed Environ Sci 22: 50-54.
    • (2009) Biomed Environ Sci , vol.22 , pp. 50-54
    • Yu, D.H.1    Bao, Y.M.2    An, L.J.3    Yang, M.4
  • 39
    • 57449116650 scopus 로고    scopus 로고
    • Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation
    • Yu S, Liu M, Gu X, Ding F,. 2008. Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation. Cell Mol Neurobiol 28: 1067-1078.
    • (2008) Cell Mol Neurobiol , vol.28 , pp. 1067-1078
    • Yu, S.1    Liu, M.2    Gu, X.3    Ding, F.4
  • 40
    • 79551491772 scopus 로고    scopus 로고
    • Anti-apoptotic effects of hyperoside via inhibition of NR2B-containing NMDA receptors
    • Zhang XN, Li JM, Yang Q, et al,. 2010. Anti-apoptotic effects of hyperoside via inhibition of NR2B-containing NMDA receptors. Pharmacol Rep 62: 949-955.
    • (2010) Pharmacol Rep , vol.62 , pp. 949-955
    • Zhang, X.N.1    Li, J.M.2    Yang, Q.3


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