Intratumoural

Journal of Controlled Release

Volumn 39, Issue 1, 1996, Pages 35-46

  Steyger, P S ^a   Baban, D F ^b   Brereton, M ^b   Ulbrich, K ^c   Seymour, L W ^b  

^a RS Dow Neurological Sciences Institute   (United States)

^b UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

^c INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

Author keywords

Drug delivery; Enhanced permeability and retention effect; Polymer conjugate; Vascular endothelial growth factor (VEGF); Vascular permeability

Indexed keywords

COPOLYMER; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; IODINE 125; MESSENGER RNA; N (2 HYDROXYPROPYL)METHACRYLAMIDE; PRODRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CANCER CELL CULTURE; CANCER GRAFT; CHEMOSENSITIVITY; COLORECTAL CARCINOMA; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG RESPONSE; EXTRAVASATION; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; LEUKEMIA P 388; MALE; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029965366     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-3659(95)00131-X     Document Type: Article

References (32)

1. S.K. Huang, E. Mayhew, S. Gilani, D.D. Lasic, F.J. Martin and D. Paphadjopoulos, Pharmacokinetics and therapeutics of sterically stabilised liposomes in mice bearing C26 colon carcinoma, Cancer Res. 52 (1992) 6774-6781.
2. A.A. Gabizon, R. Catane, B. Uziely, B. Kaufman, T. Safra, R. Cohen, F. Martin, A. Huang and Y. Barenholz, Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes, Cancer Res. 54 (1994) 987-992.
3. A. Bernstein, E. Hurwitz, M. maron, R. Arnon, M. Sela and M. Wilchek, Higher antitumour efficacy of daunomycin when linked to dextran: in vivo and in vitro studies, J. Natl. Cancer Inst. 60 (1978) 379-386.
4. J. Cassidy, R. Duncan, G.J. Morrisson, J. Strohalm, D. Plocova, J. Kopecek and S.B. Kaye, Activity of N-(2-hydroxypropyl)methacrylamide copolymers containing daunomycin against a rat tumour model, Biochem. Pharmacol. 38 (1989) 875-880.
5. M. Yokoyama, T. Okano, Y. Sakurai, H. Ekimoto, C. Shibazaki and K. Kataoka, Toxicity and antitumour activity against solid tumours of micelle-forming polymeric anti-cancer drug and its extremely long circulation in blood, Cancer Res. 51 (1991) 3229-3236.
6. R. Duncan, Drug-polymer conjugates: potential for improved chemotherapy, Anticancer Drugs 3 (1992) 175-210.
7. R. Duncan, L.W. Seymour, K.B. O'Hare, P.A. Flanagan, S. Wedge, K. Ulbrich, J. Strohalm, V. Subr, F. Spreafico, M. Grandi, M. Ripamonti, M. Farao and A. Suarato, Preclinical evaluation of polymer-bound doxorubicin, J. Control. Release 19 (1992) 331-346.
8. E.D. Day, J.A. Palnisek and M.D. Pressman, Localization of radioiodinated rat fibrinogen in transplanted rat tumours, J. Natl. Cancer Inst. 23 (1959) 799-805.
9. J. Hradec, Metabolism of serum albumin in tumour-bearing rats, Br. J. Cancer 12 (1961) 290-294.
10. H.I. Peterson and K.L. Appelgren, Experimental studies on the use and retention of labelled proteins in a rat tumour, Eur. J. Cancer 9 (1973) 543-548.
11. H.F. Dvorak, V.S. Harvey and J. McDonagh, Quantitation of fibrinogen influx and fibrin deposition and turnover in Line 1 and Line 10 guinea pig carcinomas, Cancer Res. 44 (1984) 3348-3354.
12. H. Maeda and Y. Matsumura, A new concept for macromolecular therapeutics in cancer therapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS, Cancer Res. 46 (1986) 6387-6392.
13. Y. Takakura, T. Fujita, M. Hashida and H. Sezaki, Disposition characteristics of macromolecules in tumour-bearing mice, Pharm. Res. 7 (1990) 339-436.
14. L.W. Seymour, K. Ulbrich, P.S. Steyger, M. Brereton, V. Subr, J. Strohalm and R. Duncan, Tumour tropism and anticancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma, Br. J. Cancer 70 (1994) 636-641.
15. L.W. Seymour, Y. Miyamoto, H. Maeda, M. Brereton, J. Strohalm, K. Ulbrich and R. Duncan, Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier, Eur. J. Cancer 31A (1995) 766-770.
16. L.W. Seymour, Passive tumour-targeting of macromolecules and drug conjugates, Crit. Rev. Ther. Drug Carrier Syst. 9 (1992) 135-187.
17. D.R. Senger, S.J. Galli, M. Dvorak, C.A. Perruzzi, V.S. Harvey and H.F. Dvorak, Tumour cells secrete a vascular permeability factor that promotes accumulation of ascites fluid, Science 219 (1983) 983-985.
18. L.W. Seymour, R. Duncan, J. Strohalm and J. Kopecek, Effect of molecular weight of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal and intravenous administration to rats, J. Biomed. Mater. Res. 21 (1987) 1341-1358.
19. S. Vansteenkiste, E. Schacht, R. Dunan, L. Seymour, I. Pawluczyk and R. Balswin, Fate of glycosylated dextrans after in vivo administration, J. Control. Release 16 (1991) 91-100.
20. L.W. Seymour, P.A. Flanagan, A. Al-Shamkhani, V. Subr, K. Ulhrich, J. Cassidy and R. Duncan, Synthetic polymers conjugated to monoclonal antibodies: vehicles for tumour-targeted drug delivery, Select. Cancer Ther. 7 (1991) 59-73.
21. P. Chomczynski and N. Sacchi, Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal. Biochem. 162 (1987) 156-159.
22. R.T. D-Aquila, L.J. Bechtel, J.A. Videler, J.J. Eron, P. Gorczya and J.C. Kaplan, Maximising sensitivity and specificity of PCR by pre-amplification heating, Nucl. Acids Res. 19 (1991) 3749.
23. R.C. Tripathi and B.J. Tripathi, A new method for light and electron microscopic localization of fluorescein-labelled dextran in ocular tissue using epoxy-resin embedding, Exp. Eye Res. 25 (1977) 259-264.
24. N. Thorball, FITC-dextran tracers in microcirculatory and permeability studies using combined fluorescence stereo microscopy, fluorescence microscopy and electron microscopy, Histochemistry 71 (1977) 209-233.
25. P.S. Steyger, D.N. Furness, C.M. Hackney and G.P. Richardson, Tubulin and microtubules in cochlear hair cells : Comparative immunocytochemistry and ultrastructure, Hearing Res. 42 (1990) 1-16.
26. S.R. Wedge, Mechanism of action of polymer-anthracyclines; potential to overcome multidrug resistance, Ph.D. Thesis, University of Keele, UK, 1992.
27. W.G. Roberts and T. Hasan, Tumor-secreted vascular permeability factor/vascular endothelial growth factor influences photosensitizer uptake, Cancer Res. 53 (1993) 153-157.
28. T.R. Shockley, K. Lin, J.A. Nagy, R.G. Tompkins, M.L. Yarmush and H.A. Dvorak, Spatial distribution of tumour-specific monoclonal antibodies in human melanoma xenografts, Cancer Res. 52 (1992) 367-376.
29. L.T. Baxter and R.K. Jain, Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure, Cancer Res. 48 (1988) 7022-7032.
30. R.K. Jain, Vascular and interstitial barriers to the delivery of therapeutic agents in tumours, Cancer Metast. Rev. 9 (1991) 253-266.
31. R.K. Jain, Barriers to drug delivery in solid tumors, Sci. Am. 271 (1994) 58-65.
32. Y. Boucher, J.M. Kirkwood, D. Opacic, M. Desantis and R.K. Jain, Interstitial hypertension in superficial metastatic melanomas in humans, Cancer Res. 51 (1991) 6691-6694.