메뉴 건너뛰기




Volumn 348, Issue 1, 2014, Pages 59-68

Chemopreventive effects of an HDAC2-selective inhibitor on rat colon carcinogenesis and apcmin1 mouse intestinal tumorigenesiss

Author keywords

[No Author keywords available]

Indexed keywords

AR 42; CELL CYCLE PROTEIN; CELL DIVISION CYCLE HOMOLOG 25C; CYCLIN DEPENDENT KINASE 2; CYCLINE; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE INHIBITOR; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG; VORINOSTAT;

EID: 84890541495     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.208645     Document Type: Article
Times cited : (12)

References (49)
  • 2
    • 0035959853 scopus 로고    scopus 로고
    • Role of lxcxe motif-dependent interactions in the activity of the retinoblastoma protein
    • Chan HM, Smith L, and La Thangue NB (2001) Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein. Oncogene 20:6152-6163.
    • (2001) Oncogene , vol.20 , pp. 6152-6163
    • Chan, H.M.1    Smith, L.2    La Thangue, N.B.3
  • 3
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M (2008) Epigenetics in cancer. N Engl J Med 358:1148-1159.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 5
    • 33751177396 scopus 로고    scopus 로고
    • Final results of a phase i study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxyamic acid, saha) in patients with leukemia and myelodysplastic syndrome
    • Garcia-Manero G, Yang H, Bueso-Ramos C, Ferrajoli A, Cortes J, Wierda WG, Faderl S, Koller C, Morris G, and Rosner G, et al. (2005) Final results of a phase I study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxyamic acid, SAHA) in patients with leukemia and myelodysplastic syndrome. Blood 106:785a.
    • (2005) Blood , vol.106
    • Garcia-Manero, G.1    Yang, H.2    Bueso-Ramos, C.3    Ferrajoli, A.4    Cortes, J.5    Wierda, W.G.6    Faderl, S.7    Koller, C.8    Morris, G.9    Rosner, G.10
  • 7
    • 0030798245 scopus 로고    scopus 로고
    • Histone acetylation in chromatin structure and transcription
    • Grunstein M (1997) Histone acetylation in chromatin structure and transcription. Nature 389:349-352.
    • (1997) Nature , vol.389 , pp. 349-352
    • Grunstein, M.1
  • 8
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA (2000) The hallmarks of cancer. Cell 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 9
    • 34248208217 scopus 로고    scopus 로고
    • Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-dna binding activity
    • Harms KL and Chen X (2007) Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity. Cancer Res 67: 3145-3152.
    • (2007) Cancer Res , vol.67 , pp. 3145-3152
    • Harms, K.L.1    Chen, X.2
  • 11
    • 0033615352 scopus 로고    scopus 로고
    • Ppardelta is an apcregulated target of nonsteroidal anti-inflammatory drugs
    • He TC, Chan TA, Vogelstein B, and Kinzler KW (1999) PPARdelta is an APCregulated target of nonsteroidal anti-inflammatory drugs. Cell 99:335-345.
    • (1999) Cell , vol.99 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 12
    • 17144371342 scopus 로고    scopus 로고
    • Novel link between e2f and p53: Proapoptotic cofactors of p53 are transcriptionally upregulated by e2f
    • Hershko T, Chaussepied M, Oren M, and Ginsberg D (2005) Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F. Cell Death Differ 12:377-383.
    • (2005) Cell Death Differ , vol.12 , pp. 377-383
    • Hershko, T.1    Chaussepied, M.2    Oren, M.3    Ginsberg, D.4
  • 13
    • 17144378591 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase 2 increases apoptosis and p21cip1/ waf1 expression, independent of histone deacetylase 1
    • Huang BH, Laban M, Leung CH, Lee L, Lee CK, Salto-Tellez M, Raju GC, and Hooi SC (2005) Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/ WAF1 expression, independent of histone deacetylase 1. Cell Death Differ 12: 395-404.
    • (2005) Cell Death Differ , vol.12 , pp. 395-404
    • Huang, B.H.1    Laban, M.2    Leung, C.H.3    Lee, L.4    Lee, C.K.5    Salto-Tellez, M.6    Raju, G.C.7    Hooi, S.C.8
  • 14
    • 0037380598 scopus 로고    scopus 로고
    • Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
    • JiangM and Milner J (2003) Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells. Genes Dev 17:832-837.
    • (2003) Genes Dev , vol.17 , pp. 832-837
    • Jiang, M.1    Milner, J.2
  • 16
    • 0034617261 scopus 로고    scopus 로고
    • Histone deacetylases specifically down-regulate p53-dependent gene activation
    • Juan LJ, Shia WJ, Chen MH, Yang WM, Seto E, Lin YS, and Wu CW (2000) Histone deacetylases specifically down-regulate p53-dependent gene activation. J Biol Chem 275:20436-20443.
    • (2000) J Biol Chem , vol.275 , pp. 20436-20443
    • Juan, L.J.1    Shia, W.J.2    Chen, M.H.3    Yang, W.M.4    Seto, E.5    Lin, Y.S.6    Wu, C.W.7
  • 17
    • 84859565614 scopus 로고    scopus 로고
    • Hdac2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins
    • Jung KH, Noh JH, Kim JK, Eun JW, Bae HJ, Xie HJ, Chang YG, Kim MG, Park H, and Lee JY, et al. (2012) HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins. J Cell Biochem 113:2167-2177.
    • (2012) J Cell Biochem , vol.113 , pp. 2167-2177
    • Jung, K.H.1    Noh, J.H.2    Kim, J.K.3    Eun, J.W.4    Bae, H.J.5    Xie, H.J.6    Chang, Y.G.7    Kim, M.G.8    Park, H.9    Lee, J.Y.10
  • 20
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW and Vogelstein B (1996) Lessons from hereditary colorectal cancer. Cell 87:159-170.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 23
    • 0034654011 scopus 로고    scopus 로고
    • Acetylation: A regulatory modification to rival phosphorylation?
    • Kouzarides T (2000) Acetylation: a regulatory modification to rival phosphorylation? EMBO J 19:1176-1179.
    • (2000) EMBO J , vol.19 , pp. 1176-1179
    • Kouzarides, T.1
  • 24
    • 84872475091 scopus 로고    scopus 로고
    • Blocking the class i histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating tgf-beta and egfr signaling
    • Liu N, He S, Ma L, Ponnusamy M, Tang J, Tolbert E, Bayliss G, Zhao TC, Yan H, and Zhuang S (2013) Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signaling. PLoS ONE 8:e54001.
    • (2013) PLoS ONE , vol.8
    • Liu, N.1    He, S.2    Ma, L.3    Ponnusamy, M.4    Tang, J.5    Tolbert, E.6    Bayliss, G.7    Zhao, T.C.8    Yan, H.9    Zhuang, S.10
  • 26
    • 72449176846 scopus 로고    scopus 로고
    • Molecular basis of colorectal cancer
    • Markowitz SD and Bertagnolli MM (2009) Molecular basis of colorectal cancer. New Engl J Med 361:2449-2460.
    • (2009) New Engl J Med , vol.361 , pp. 2449-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 27
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • Minucci S and Pelicci PG (2006) Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat Rev Cancer 6:38-51.
    • (2006) Nat Rev Cancer , vol.6 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 28
    • 84863708472 scopus 로고    scopus 로고
    • National Cancer Institute Available at: Accessed 12 October 2013
    • National Cancer Institute (2013) Cancer facts and figures. Available at: http://www.cancer.gov/cancertopics/types/colon-and-rectal. Accessed 12 October 2013.
    • (2013) Cancer facts and figures
  • 30
    • 81755176121 scopus 로고    scopus 로고
    • Aberrant regulation of hdac2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of g1/s cell cycle proteins
    • Noh JH, Jung KH, Kim JK, Eun JW, Bae HJ, Xie HJ, Chang YG, Kim MG, Park WS, and Lee JY, et al. (2011) Aberrant regulation of HDAC2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of G1/S cell cycle proteins. PLoS ONE 6:e28103.
    • (2011) PLoS ONE , vol.6
    • Noh, J.H.1    Jung, K.H.2    Kim, J.K.3    Eun, J.W.4    Bae, H.J.5    Xie, H.J.6    Chang, Y.G.7    Kim, M.G.8    Park, W.S.9    Lee, J.Y.10
  • 31
    • 33644836549 scopus 로고    scopus 로고
    • Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies
    • O'Connor OA, Heaney ML, Schwartz L, Richardson S, Willim R, MacGregor-Cortelli B, Curly T, Moskowitz C, Portlock C, and Horwitz S,, et al. (2006) Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies. J Clin Oncol 24:166-173.
    • (2006) J Clin Oncol , vol.24 , pp. 166-173
    • O'Connor, O.A.1    Heaney, M.L.2    Schwartz, L.3    Richardson, S.4    Willim, R.5    MacGregor-Cortelli, B.6    Curly, T.7    Moskowitz, C.8    Portlock, C.9    Horwitz, S.10
  • 32
    • 0033579412 scopus 로고    scopus 로고
    • Regulation of the p53 tumor suppressor protein
    • Oren M (1999). Regulation of the p53 tumor suppressor protein. J Biol Chem 274: 36031-36034.
    • (1999) J Biol Chem , vol.274 , pp. 36031-36034
    • Oren, M.1
  • 33
    • 0026583746 scopus 로고
    • Cyclin a is required at two points in the human cell cycle
    • Pagano M, Pepperkok R, Verde F, Ansorge W, and Draetta G (1992) Cyclin A is required at two points in the human cell cycle. EMBO J 11:961-971.
    • (1992) EMBO J , vol.11 , pp. 961-971
    • Pagano, M.1    Pepperkok, R.2    Verde, F.3    Ansorge, W.4    Draetta, G.5
  • 36
    • 0036463649 scopus 로고    scopus 로고
    • Apoptosis-based therapies
    • Reed JC (2002) Apoptosis-based therapies. Nat Rev Drug Discov 1:111-121.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 111-121
    • Reed, J.C.1
  • 37
    • 0026532413 scopus 로고
    • Human cyclin-dependent kinase 2 is activated during the s and g2 phases of the cell cycle and associates with cyclin a
    • Rosenblatt J, Gu Y, and Morgan DO (1992) Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. Proc Natl Acad Sci USA 89:2824-2828.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 2824-2828
    • Rosenblatt, J.1    Gu, Y.2    Morgan, D.O.3
  • 41
  • 42
    • 0033230581 scopus 로고    scopus 로고
    • The cellular response to p53: The decision between life and death
    • Sionov RV and Haupt Y (1999) The cellular response to p53: the decision between life and death. Oncogene 18:6145-6157.
    • (1999) Oncogene , vol.18 , pp. 6145-6157
    • Sionov, R.V.1    Haupt, Y.2
  • 43
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl BD and Allis CD (2000) The language of covalent histone modifications. Nature 403:41-45.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 45
    • 38949086502 scopus 로고    scopus 로고
    • Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and hdac2 expression is associated with shorter psa relapse time after radical prostatectomy
    • Weichert W, Röske A, Gekeler V, Beckers T, Stephan C, Jung K, Fritzsche FR, Niesporek S, Denkert C, and Dietel M, et al. (2008) Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy. Br J Cancer 98: 604-610.
    • (2008) Br J Cancer , vol.98 , pp. 604-610
    • Weichert, W.1    Röske, A.2    Gekeler, V.3    Beckers, T.4    Stephan, C.5    Jung, K.6    Fritzsche, F.R.7    Niesporek, S.8    Denkert, C.9    Dietel, M.10
  • 46
    • 61849144810 scopus 로고    scopus 로고
    • Hdac family: What are the cancer relevant targets?
    • Witt O, Deubzer HE, Milde T, and Oehme I (2009) HDAC family: What are the cancer relevant targets? Cancer Lett 277:8-21.
    • (2009) Cancer Lett , vol.277 , pp. 8-21
    • Witt, O.1    Deubzer, H.E.2    Milde, T.3    Oehme, I.4
  • 48
    • 0032582671 scopus 로고    scopus 로고
    • Cloning and characterization of the mouse histone deacetylase-2 gene
    • Zeng Y, Tang CM, Yao YL, Yang WM, and Seto E (1998) Cloning and characterization of the mouse histone deacetylase-2 gene. J Biol Chem 273:28921-28930.
    • (1998) J Biol Chem , vol.273 , pp. 28921-28930
    • Zeng, Y.1    Tang, C.M.2    Yao, Y.L.3    Yang, W.M.4    Seto, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.