FACS analysis of neuronal-glial interactions in the nucleus accumbens following morphine administration

Psychopharmacology

Volumn 230, Issue 4, 2013, Pages 525-535

  Schwarz, Jaclyn M ^a,b   Smith, Susan H ^a   Bilbo, Staci D ^a  

^a DUKE UNIVERSITY   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

Author keywords

Astrocytes; Chemokines; Dopamine; Microglia; Opioid

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; MORPHINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL INTERACTION; DOPAMINE RELEASE; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GLIA CELL; IMMUNE RESPONSE; MICROGLIA; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

ANALGESICS, OPIOID; ANIMALS; ASTROCYTES; CHEMOKINES; CYTOKINES; DOPAMINE; DRUG-SEEKING BEHAVIOR; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; MALE; MICROGLIA; MORPHINE; NEURONS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84890433606     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-013-3180-z     Document Type: Article

References (20)

1. Basu S, Dasgupta PS (2000) Dopamine, a neurotransmitter, influences the immune system. J Neuroimmuno 102:113-124
2. Biber K, Neumann H, Inoue K, Boddeke HW (2007) Neuronal 'On' and 'Off' signals control microglia. Trends Neurosci 30:596-602
3. Centonze D, Grande C, Usiello A, Gubellini P, Erbs E, Martin AB, Pisani A, Tognazzi N, Bernardi G, Moratalla R, Borrelli E, Calabresi P (2003) Receptor subtypes involved in the presynaptic and postsynaptic actions of dopamine on striatal interneurons. J Neurosci 23:6245-6254
4. Färber K, Pannasch U, Kettenmann H (2005) Dopamine and noradrenaline control distinct functions in rodent microglial cells. Mol Cell Neurosci 29:128-138
5. Feng G, Mellor RH, Bernstein M, Keller-Peck C, Nguyen QT, Wallace M, Nerbonne JM, Lichtman JW, Sanes JR (2000) Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28:41-51
6. Gaskill PJ, Carvallo L, Eugenin EA, Berman JW (2012) Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse. J Neuroinflamm 9:203-217
7. Huang Y, Smith DE, Ibañez-Sandoval O, Sims JE, Friedman WJ (2011) Neuron-specific effects of interleukin-1β ar emediated by a novel isoform of the IL-1 receptor accessory protein. J Neurosci 31:18048-18059
8. Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, Falke JJ, Leinwand LA, Maier SF, Yin H, Rice KC, Watkins LR (2010) Evidence that opioids may have Toll-like receptor 4 and MD-2 effects. Brain Behav Immun 24:83-95
9. Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, Maslanik T, Chapman TR, Strand KA, Fleshner M, Bachtell RK, Somogyi AA, Yin H, Katz JL, Rice KC, Maier SF, Watkins LR (2012) Opioid activation of Toll-like receptor 4 contributes to drug reinforcement. J Neurosci 32:11187-11200
10. Meng X, Zhang Y, Lao L, Saito R, Li A, Bäckman CM, Berman BM, Ren K, Wei PK, Zhang RX (2013) Spinal interleukin1 promotes thermal hyperalgesia and NMDA NR1 phosphorylation in an inlammatory pain rat model. Pain 154:294-305
11. Nishiyori A, Minami M, Ohtani Y, Takami S, Yamamoto J, Nami K, Kume T, Akaike A, Satoh M (1998) Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia? FEBS Lett 429:167-172
12. Noain D, Avale ME, Wedemeyer C, Calvo D, Peper M, Rubinstein M (2006) Identification of brain neurons expressing the dopamine D4 receptor gene using BAC transgenic mice. Eur J Neurosci 24:2429-2438
13. Sarkar C, Basu B, Chakroborty D, Dasgupta PS, Basu S (2010) The immunoregulatory role of dopamine: an update. Brain Behav Immun 24:525-528
14. Schwarz JM, Bilbo SD (2013) Adolescent morphine exposure affects long-term microglial function and later-life relapse liability in a model of addiction. J Neurosci 33:961-971
15. Schwarz JM, Hutchinson MR, Bilbo SD (2011) Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. J Neurosci 31:17835-17847
16. Srinivasan D, Yen JH, Joseph DJ, Friedman W (2004) Cell-type specific interleukin-1β signaling in the CNS. J Neurosci 24:6482-6488
17. Wang X, Loram LC, Ramos K, de Jesus AJ, Thomas J, Cheng K, Reddy A, Somogyi AA, Hutchinson MR, Watkins LR, Yin H (2012) Morphine activates neuroinflammation in a manner parallel to endotoxin. Proc Natl Acad Sci U S A 109:6325-6330
18. Williamson LL, Sholar PW, Mistry, RS, Smith SH, Bilbo SD (2011) Microglia and memory: modulation by early-life infection. J Neurosci 31:15511-15521
19. Wolf Y, Yona S, Kim KW, Jung S (2013) Microglia, seen from the CX3CR1 angle. Front Cell Neurosci 7:26
20. Zujovic V, Benavides J, Vigé X, Carter C, Taupin V (2000) Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation. Glia 29:305-315