Transgenic expression of GM-CSF in T cells causes disseminated histiocytosis

American Journal of Pathology

Volumn 184, Issue 1, 2014, Pages 184-199

  Van Nieuwenhuijze, Annemarie E ^a   Coghill, Elise ^a   Gray, Daniel ^a,b   Prato, Sandro ^a,b   Metcalf, Donald ^a,b   Alexander, Warren S ^a,b   Wicks, Ian P ^a,b,c  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 5; PROTEIN KINASE LCK; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CELL; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL POPULATION; COLONY FORMING CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; EMBRYO; FEMALE; GENE OVEREXPRESSION; GENETIC ENGINEERING; HISTIOCYTE; HISTIOCYTOSIS; HISTOPATHOLOGY; IN VIVO STUDY; LANGERHANS CELL HISTIOCYTOSIS; LYMPH NODE CELL; LYMPHADENOPATHY; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; LYMPHOID ORGAN; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY T LYMPHOCYTE; SPLEEN CELL; SPLENOMEGALY; T LYMPHOCYTE; TH17 CELL; THYMOCYTE; THYMUS; THYMUS ATROPHY; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; BLOTTING, SOUTHERN; CELL DIFFERENTIATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HISTIOCYTOSIS; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 84890424208     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.09.014     Document Type: Article

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