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Volumn 38, Issue 19, 2013, Pages 3239-3245

Advance in studies on biotransformation of flavonoids by intestinal bacteria

Author keywords

Biotransformation; Flavonoids; Impacting factor; Intestinal bacteria; Reaction type

Indexed keywords

FLAVONOID;

EID: 84890396776     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20131904     Document Type: Review
Times cited : (10)

References (52)
  • 1
    • 70349332586 scopus 로고    scopus 로고
    • Mechanism of action of flavonoids as anti-inflammatory agents: A review
    • Rathee P, Chaudhary H, Rathee S, et al. Mechanism of action of flavonoids as anti-inflammatory agents: a review [J]. Inflamm Allergy Drug Targets, 2009, 8(3): 229.
    • (2009) Inflamm Allergy Drug Targets , vol.8 , Issue.3 , pp. 229
    • Rathee, P.1    Chaudhary, H.2    Rathee, S.3
  • 2
    • 65649100099 scopus 로고    scopus 로고
    • Flavonoids, vascular function and cardiovascular protection
    • Grassi D, Desideri G, Croce G, et al. Flavonoids, vascular function and cardiovascular protection [J]. Curr Pharm Des, 2009, 15 (10): 1072.
    • (2009) Curr Pharm Des , vol.15 , Issue.10 , pp. 1072
    • Grassi, D.1    Desideri, G.2    Croce, G.3
  • 3
    • 0036898114 scopus 로고    scopus 로고
    • The clinical importance of the metabolite equol - A clue to the effectiveness of soy and its isoflavones
    • Setchell K D, Brown N M, Lydeking-Olsen E. The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones [J]. J Nutr, 2002, 132(12): 3577.
    • (2002) J Nutr , vol.132 , Issue.12 , pp. 3577
    • Setchell, K.D.1    Brown, N.M.2    Lydeking-Olsen, E.3
  • 4
    • 84861476719 scopus 로고    scopus 로고
    • EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity
    • Lee Y H, Kwak J, Choi H K, et al. EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity [J]. Int J Mol Med, 2012, 30(1): 69.
    • (2012) Int J Mol Med , vol.30 , Issue.1 , pp. 69
    • Lee, Y.H.1    Kwak, J.2    Choi, H.K.3
  • 5
    • 85081792544 scopus 로고    scopus 로고
    • Chinese source
    • 2011, 42(11): 2335.
    • (2011) , vol.42 , Issue.11 , pp. 2335
  • 6
    • 32944466887 scopus 로고    scopus 로고
    • Ecological and evolutionary forces shaping microbial diversity in the human intestine
    • Ley R E, Peterson D A, Gordon J I. Ecological and evolutionary forces shaping microbial diversity in the human intestine [J]. Cell, 2006, 124(4): 837.
    • (2006) Cell , vol.124 , Issue.4 , pp. 837
    • Ley, R.E.1    Peterson, D.A.2    Gordon, J.I.3
  • 7
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Arumugam M, et al. A human gut microbial gene catalogue established by metagenomic sequencing [J]. Nature, 2010, 464(7285): 59.
    • (2010) Nature , vol.464 , Issue.7285 , pp. 59
    • Qin, J.1    Li, R.2    Arumugam, M.3
  • 8
    • 79953733693 scopus 로고    scopus 로고
    • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
    • Wang Z, Elizabeth K, Brian J. B, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease [J]. Nature, 2011, 472(7341): 57.
    • (2011) Nature , vol.472 , Issue.7341 , pp. 57
    • Wang, Z.1    Elizabeth, K.2    Brian, J.B.3
  • 9
    • 85081801477 scopus 로고    scopus 로고
    • Chinese source
    • 2005, 4(4): 39.
    • (2005) , vol.4 , Issue.4 , pp. 39
  • 10
    • 85081794593 scopus 로고    scopus 로고
    • Chinese source
    • 2006, 5(3): 30.
    • (2006) , vol.5 , Issue.3 , pp. 30
  • 11
    • 84867746407 scopus 로고    scopus 로고
    • Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations
    • Zhang C, Zhang M, Pang X, et al. Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations [J]. ISME J, 2012, 6(10): 1848.
    • (2012) ISME J , vol.6 , Issue.10 , pp. 1848
    • Zhang, C.1    Zhang, M.2    Pang, X.3
  • 12
    • 85027927719 scopus 로고    scopus 로고
    • Enterotypes of the human gut microbiome
    • Arumugam M, Raes J, Pelletier E, et al. Enterotypes of the human gut microbiome [J]. Nature, 2011, 473(7346): 174.
    • (2011) Nature , vol.473 , Issue.7346 , pp. 174
    • Arumugam, M.1    Raes, J.2    Pelletier, E.3
  • 13
    • 84864722033 scopus 로고    scopus 로고
    • Gut microbiota composition correlates with diet and health in the elderly
    • Claesson M J, Jeffery I B, Conde S, et al. Gut microbiota composition correlates with diet and health in the elderly [J]. Nature, 2012, 488(7410): 178.
    • (2012) Nature , vol.488 , Issue.7410 , pp. 178
    • Claesson, M.J.1    Jeffery, I.B.2    Conde, S.3
  • 14
    • 85081796892 scopus 로고    scopus 로고
    • Chinese source
    • 2011, 36(1): 19.
    • (2011) , vol.36 , Issue.1 , pp. 19
  • 15
    • 85081801111 scopus 로고    scopus 로고
    • Chinese source
    • 2010, 34(5): 79.
    • (2010) , vol.34 , Issue.5 , pp. 79
  • 16
    • 0033978259 scopus 로고    scopus 로고
    • Anaerobic degradation of flavonoids by Eubacterium ramulus
    • Schneider H, Blaut M. Anaerobic degradation of flavonoids by Eubacterium ramulus [J]. Arch Microbiol, 2000, 173(1): 71.
    • (2000) Arch Microbiol , vol.173 , Issue.1 , pp. 71
    • Schneider, H.1    Blaut, M.2
  • 17
    • 0142104439 scopus 로고    scopus 로고
    • Anaerobic degradation of flavonoids by Clostridium orbiscindens
    • Schoefer L, Mohan R, Schwiertz A, et al. Anaerobic degradation of flavonoids by Clostridium orbiscindens [J]. Appl Environ Microbiol, 2003, 69(10): 5849.
    • (2003) Appl Environ Microbiol , vol.69 , Issue.10 , pp. 5849
    • Schoefer, L.1    Mohan, R.2    Schwiertz, A.3
  • 18
    • 84868613767 scopus 로고    scopus 로고
    • Intestinal bacterium Eubacterium cellulosolvens deglycosylates flavonoid C-and O-glucosides
    • Braune A, Blaut M. Intestinal bacterium Eubacterium cellulosolvens deglycosylates flavonoid C-and O-glucosides [J]. Appl Environ Microbiol, 2012, 78(22): 8151.
    • (2012) Appl Environ Microbiol , vol.78 , Issue.22 , pp. 8151
    • Braune, A.1    Blaut, M.2
  • 19
    • 85081794718 scopus 로고    scopus 로고
    • Chinese source
    • 2009, 49(4): 479.
    • (2009) , vol.49 , Issue.4 , pp. 479
  • 20
    • 0031987813 scopus 로고    scopus 로고
    • Intestinal bacterial metabolism of flavonoids and its relation to some biological activities
    • Kim D H, Jung E A, Sohng I S, et al. Intestinal bacterial metabolism of flavonoids and its relation to some biological activities [J]. Arch Pharm Res, 1998, 21(1): 17.
    • (1998) Arch Pharm Res , vol.21 , Issue.1 , pp. 17
    • Kim, D.H.1    Jung, E.A.2    Sohng, I.S.3
  • 21
    • 48849106250 scopus 로고    scopus 로고
    • Biotransformation of C-glucosylisoflavone puerarin to estrogenic (3S)-equol in co-culture of two human intestinal bacteria
    • Jin J S, Nishihata T, Kakiuchi N, et al. Biotransformation of C-glucosylisoflavone puerarin to estrogenic (3S)-equol in co-culture of two human intestinal bacteria [J]. Biol Pharm Bull, 2008, 31(8): 1621.
    • (2008) Biol Pharm Bull , vol.31 , Issue.8 , pp. 1621
    • Jin, J.S.1    Nishihata, T.2    Kakiuchi, N.3
  • 22
    • 78650849540 scopus 로고    scopus 로고
    • The C-glucosyl bond of puerarin was cleaved hydrolytically by a human intestinal bacterium strain PUE to yield its aglycone daidzein and an intact glucose
    • Nakamura K, Nishihata T, Jin J S, et al. The C-glucosyl bond of puerarin was cleaved hydrolytically by a human intestinal bacterium strain PUE to yield its aglycone daidzein and an intact glucose [J]. Chem Pharm Bull, 2011, 59(1): 23.
    • (2011) Chem Pharm Bull , vol.59 , Issue.1 , pp. 23
    • Nakamura, K.1    Nishihata, T.2    Jin, J.S.3
  • 23
    • 85081792665 scopus 로고    scopus 로고
    • Chinese source
    • 2011, 36(4), 443.
    • (2011) , vol.36 , Issue.4 , pp. 443
  • 24
    • 0034544829 scopus 로고    scopus 로고
    • Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistin
    • Hur H G, Lay J O Jr, Beger R D, et al. Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistin [J]. Arch Microbiol, 2000, 174(6): 422.
    • (2000) Arch Microbiol , vol.174 , Issue.6 , pp. 422
    • Hur, H.G.1    Lay, Jr.J.O.B.R.D.2
  • 25
    • 0037359126 scopus 로고    scopus 로고
    • Transformation of flavonoids by intestinal microorganisms
    • Blaut M, Schoefer L, Braune A. Transformation of flavonoids by intestinal microorganisms [J]. Int J Vitam Nutr Res, 2003, 73 (2): 79.
    • (2003) Int J Vitam Nutr Res , vol.73 , Issue.2 , pp. 79
    • Blaut, M.1    Schoefer, L.2    Braune, A.3
  • 26
    • 8144230744 scopus 로고    scopus 로고
    • Cloning and expression of a phloretin hydrolase gene from Eubacterium ramulus and characterization of the recombinant enzyme
    • Schoefer L, Braune A, Blaut M. Cloning and expression of a phloretin hydrolase gene from Eubacterium ramulus and characterization of the recombinant enzyme [J]. Appl Environ Microbiol, 2004, 70(10): 6131.
    • (2004) Appl Environ Microbiol , vol.70 , Issue.10 , pp. 6131
    • Schoefer, L.1    Braune, A.2    Blaut, M.3
  • 27
    • 77952096064 scopus 로고    scopus 로고
    • Isolation and characterization of the equol-producing bacterium Slackia sp. strain NATTS
    • Tsuji H, Moriyama K, Nomoto K, et al. Isolation and characterization of the equol-producing bacterium Slackia sp. strain NATTS [J]. Arch Microbiol, 2010, 192(4): 279.
    • (2010) Arch Microbiol , vol.192 , Issue.4 , pp. 279
    • Tsuji, H.1    Moriyama, K.2    Nomoto, K.3
  • 28
    • 84857080143 scopus 로고    scopus 로고
    • Identification of an enzyme system for daidzein-to-equol conversion in Slackia sp. strain NATTS
    • Tsuji H, Moriyama K, Nomoto K, et al. Identification of an enzyme system for daidzein-to-equol conversion in Slackia sp. strain NATTS [J]. Appl Environ Microbiol, 2012, 78(4): 1228.
    • (2012) Appl Environ Microbiol , vol.78 , Issue.4 , pp. 1228
    • Tsuji, H.1    Moriyama, K.2    Nomoto, K.3
  • 29
    • 79958812230 scopus 로고    scopus 로고
    • Isolation of catechin-converting human intestinal bacteria
    • Kutschera M, Engst W, Blaut M, et al. Isolation of catechin-converting human intestinal bacteria [J]. J Appl Microbiol, 2011, 111(1): 165.
    • (2011) J Appl Microbiol , vol.111 , Issue.1 , pp. 165
    • Kutschera, M.1    Engst, W.2    Blaut, M.3
  • 30
    • 84871545316 scopus 로고    scopus 로고
    • Isolation and characterization of a human intestinal bacterium Eggerthella sp. CAT-1 capable of cleaving the C-ring of (+)-catechin and (-)-epicatechin, followed by p-dehydroxylation of the B-ring
    • Jin J S, Hattori M. Isolation and characterization of a human intestinal bacterium Eggerthella sp. CAT-1 capable of cleaving the C-ring of (+)-catechin and (-)-epicatechin, followed by p-dehydroxylation of the B-ring [J]. Biol Pharm Bull, 2012; 35 (12): 2252.
    • (2012) Biol Pharm Bull , vol.35 , Issue.12 , pp. 2252
    • Jin, J.S.1    Hattori, M.2
  • 31
    • 0031009218 scopus 로고    scopus 로고
    • Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria
    • Meselhy M R, Nakamura N, Hattori M. Biotransformation of (-)-epicatechin 3-O-gallate by human intestinal bacteria [J]. Chem Pharm Bull, 1997, 45(5): 888.
    • (1997) Chem Pharm Bull , vol.45 , Issue.5 , pp. 888
    • Meselhy, M.R.1    Nakamura, N.2    Hattori, M.3
  • 32
    • 33847056543 scopus 로고    scopus 로고
    • Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces
    • Tamura M, Tsushida T, Shinohara K. Isolation of an isoflavone-metabolizing, Clostridium-like bacterium, strain TM-40, from human faeces [J]. Anaerobe, 2007, 13(1): 32.
    • (2007) Anaerobe , vol.13 , Issue.1 , pp. 32
    • Tamura, M.1    Tsushida, T.2    Shinohara, K.3
  • 33
    • 0036278213 scopus 로고    scopus 로고
    • Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein
    • Hur H G, Beger R D, Heinze T M, et al. Isolation of an anaerobic intestinal bacterium capable of cleaving the C-ring of the isoflavonoid daidzein [J]. Arch Microbiol, 2002, 178(1): 8.
    • (2002) Arch Microbiol , vol.178 , Issue.1 , pp. 8
    • Hur, H.G.1    Beger, R.D.2    Heinze, T.M.3
  • 34
    • 12244305578 scopus 로고    scopus 로고
    • Enantioselective synthesis of 5-equol from dihydrodaidzein by a newly isolated anaerobic huaman intestinal bacterium
    • Wang X L, Hur H G, Lee J H, et al. Enantioselective synthesis of 5-equol from dihydrodaidzein by a newly isolated anaerobic huaman intestinal bacterium [J]. Appl Environ Microbiol, 2005, 71(1): 214.
    • (2005) Appl Environ Microbiol , vol.71 , Issue.1 , pp. 214
    • Wang, X.L.1    Hur, H.G.2    Lee, J.H.3
  • 35
    • 84861455394 scopus 로고    scopus 로고
    • Identification of rutin deglycosy-lated metabolites produced by human intestinal bacteria using UP-LC-Q-TOF/MS
    • Yang J, Qian D, Jiang S, et al. Identification of rutin deglycosy-lated metabolites produced by human intestinal bacteria using UP-LC-Q-TOF/MS [J]. J Chromatogr B Analyt Technol Biomed Life Sci, 2012, 898: 95.
    • (2012) J Chromatogr B Analyt Technol Biomed Life Sci , vol.898 , pp. 95
    • Yang, J.1    Qian, D.2    Jiang, S.3
  • 36
    • 36649002618 scopus 로고    scopus 로고
    • Human intestinal hydrolysis of phenol glycosides: A study with quercetin and p-nitrophenol glycosides using ileostomy fluid
    • Knaup B, Kahle K, Erk T, et al. Human intestinal hydrolysis of phenol glycosides: a study with quercetin and p-nitrophenol glycosides using ileostomy fluid [J]. Mol Nutr Food Res, 2007, 51 (11): 1423.
    • (2007) Mol Nutr Food Res , vol.51 , Issue.11 , pp. 1423
    • Knaup, B.1    Kahle, K.2    Erk, T.3
  • 37
    • 0037766468 scopus 로고    scopus 로고
    • Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals
    • Rafii F, Davis C, Park M, et al. Variations in metabolism of the soy isoflavonoid daidzein by human intestinal microfloras from different individuals [J]. Arch Microbiol, 2003, 180 (1): 11.
    • (2003) Arch Microbiol , vol.180 , Issue.1 , pp. 11
    • Rafii, F.1    Davis, C.2    Park, M.3
  • 38
    • 14344267019 scopus 로고    scopus 로고
    • Gut bacterial metabolism of the soy isoflavone daidzein: Exploring the relevance to human health
    • Atkinson C, Frankenfeld C L, Lampe J W. Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health [J]. Exp Biol Med, 2005, 230(3): 155.
    • (2005) Exp Biol Med , vol.230 , Issue.3 , pp. 155
    • Atkinson, C.1    Frankenfeld, C.L.2    Lampe, J.W.3
  • 39
    • 85081793722 scopus 로고    scopus 로고
    • Chinese source
    • 2004, 39(2): 153.
    • (2004) , vol.39 , Issue.2 , pp. 153
  • 40
    • 41849099278 scopus 로고    scopus 로고
    • Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization (FISH)
    • Hein E M, Rose K, van't Slot G, et al. Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization (FISH) [J]. J Agric Food Chem, 2008, 56(6): 2281.
    • (2008) J Agric Food Chem , vol.56 , Issue.6 , pp. 2281
    • Hein, E.M.1    Rose, K.2    Van't, S.G.3
  • 41
    • 1242279337 scopus 로고    scopus 로고
    • Degradation of flavonoid aglycones by rabbit, rat and human fecal flora
    • Lin Y T, Hsiu S L, Hou Y C, et al. Degradation of flavonoid aglycones by rabbit, rat and human fecal flora [J]. Biol Pharm Bull, 2003, 26(5): 747.
    • (2003) Biol Pharm Bull , vol.26 , Issue.5 , pp. 747
    • Lin, Y.T.1    Hsiu, S.L.2    Hou, Y.C.3
  • 42
    • 75249104780 scopus 로고    scopus 로고
    • Greater apparent absorption of flavonoids is associated with lesser human fecal flavonoid disappearance rates
    • Simons A L, Renouf M, Murphy P A, et al. Greater apparent absorption of flavonoids is associated with lesser human fecal flavonoid disappearance rates [J]. J Agric Food Chem, 2010, 58 (1): 141.
    • (2010) J Agric Food Chem , vol.58 , Issue.1 , pp. 141
    • Simons, A.L.1    Renouf, M.2    Murphy, P.A.3
  • 43
    • 0035209197 scopus 로고    scopus 로고
    • The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp. strain SDG-2, a human intestinal bacterium
    • Wang L Q, Meselhy M R, Li Y, et al. The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp. strain SDG-2, a human intestinal bacterium [J]. Chem Pharm Bull, 2001, 49(12): 1640.
    • (2001) Chem Pharm Bull , vol.49 , Issue.12 , pp. 1640
    • Wang, L.Q.1    Meselhy, M.R.2    Li, Y.3
  • 44
    • 85081800517 scopus 로고    scopus 로고
    • Chinese source
    • 2010, 18(13): 1360.
    • (2010) , vol.18 , Issue.13 , pp. 1360
  • 45
    • 85081796726 scopus 로고    scopus 로고
    • Chinese source
    • 2008, 16(19): 2144.
    • (2008) , vol.16 , Issue.19 , pp. 2144
  • 46
    • 60449103715 scopus 로고    scopus 로고
    • Equol is more active than soy isoflavone itself to compete for binding to thromboxane A (2) receptor in human platelets
    • Munoz Y, Garrido A, Valladares L. Equol is more active than soy isoflavone itself to compete for binding to thromboxane A (2) receptor in human platelets [J]. Thromb Res, 2009, 123(5): 740.
    • (2009) Thromb Res , vol.123 , Issue.5 , pp. 740
    • Munoz, Y.1    Garrido, A.2    Valladares, L.3
  • 47
    • 85081796482 scopus 로고    scopus 로고
    • Chinese source
    • 2003, 28(9): 842.
    • (2003) , vol.28 , Issue.9 , pp. 842
  • 48
    • 85081791109 scopus 로고    scopus 로고
    • Chinese source
    • 2006: 7(10): 1510.
    • (2006) , vol.7 , Issue.10 , pp. 1510
  • 49
    • 85081801417 scopus 로고    scopus 로고
    • Chinese source
    • 2009, 28(6): 370.
    • (2009) , vol.28 , Issue.6 , pp. 370
  • 50
    • 80052065175 scopus 로고    scopus 로고
    • Antibiotic overuse: Stop the killing of beneficial bacteria
    • Martin B. Antibiotic overuse: stop the killing of beneficial bacteria [J]. Nature, 2011, 476(7361): 393.
    • (2011) Nature , vol.476 , Issue.7361 , pp. 393
    • Martin, B.1
  • 51
    • 84870585864 scopus 로고    scopus 로고
    • The inhibitory effect of polyphenols on human gut microbiota
    • Duda-Chodak A. The inhibitory effect of polyphenols on human gut microbiota [J]. J Physiol Pharmacol, 2012, 63 (5): 497.
    • (2012) J Physiol Pharmacol , vol.63 , Issue.5 , pp. 497
    • Duda-Chodak, A.1
  • 52
    • 85081794348 scopus 로고    scopus 로고
    • Chinese source
    • 2006, 14(10): 973.
    • (2006) , vol.14 , Issue.10 , pp. 973


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