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Volumn 8, Issue 3, 2009, Pages 229-235

Mechanism of action of flavonoids as anti-inflammatory agents: A review

Author keywords

Anti inflammatory; Cyclooxygenase activity; Flavonoids; Inflammation; Lipoxygenases

Indexed keywords

AMENTOFLAVONE; ANTHOCYANIN; APIGENIN; ARACHIDONIC ACID; CURCUMIN; CYCLIC AMP PHOSPHODIESTERASE; CYCLOOXYGENASE 2; DIOSMIN; EPIGALLOCATECHIN GALLATE; FLAVANOL DERIVATIVE; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; HESPERIDIN; HISTAMINE RELEASE INHIBITOR; HYDROCINNAMIC ACID; ISOFLAVONE DERIVATIVE; LUTEOLIN; PHOSPHODIESTERASE; PHOSPHORYLASE KINASE; PROCYANIDIN DERIVATIVE; PROSTAGLANDIN SYNTHASE; PROSTANOID; QUERCETIN; RESVERATROL; STILBENE DERIVATIVE; AUTACOID; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN KINASE; PROTEIN KINASE INHIBITOR;

EID: 70349332586     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152809788681029     Document Type: Review
Times cited : (375)

References (51)
  • 1
    • 0031708667 scopus 로고    scopus 로고
    • Effect of plant flavonoids on immune and inflammatory cell function
    • Middleton, E.J. Effect of plant flavonoids on immune and inflammatory cell function. Adv. Exp. Med. Biol., 1998, 439, 175-182.
    • (1998) Adv. Exp. Med. Biol , vol.439 , pp. 175-182
    • Middleton, E.J.1
  • 2
    • 0030775534 scopus 로고    scopus 로고
    • Absorption, metabolism and health effects of dietary flavonoids in man
    • Hollman, P.H.; Batan, M.B. Absorption, metabolism and health effects of dietary flavonoids in man. Biomed. Pharmacother., 1997, 51, 305-310.
    • (1997) Biomed. Pharmacother , vol.51 , pp. 305-310
    • Hollman, P.H.1    Batan, M.B.2
  • 3
    • 0031839464 scopus 로고    scopus 로고
    • Tissue injury by reactive oxygen species and the protective effects of flavonoids
    • De Groot, H.; Rauen, U. Tissue injury by reactive oxygen species and the protective effects of flavonoids. Fundam Clin. Pharmacol., 1998, 12, 249-255.
    • (1998) Fundam Clin. Pharmacol , vol.12 , pp. 249-255
    • De Groot, H.1    Rauen, U.2
  • 4
    • 0035076924 scopus 로고    scopus 로고
    • Bioflavonoidsclassification, pharmacological, Biochemical effects and therapeutic potential
    • Narayana, K.R.; Reddy, M.S.; Chaluvadi, M.R.; Krishna, D.R. Bioflavonoidsclassification, pharmacological, Biochemical effects and therapeutic potential. Ind. J. Pharmacol., 2001, 33, 2-16.
    • (2001) Ind. J. Pharmacol , vol.33 , pp. 2-16
    • Narayana, K.R.1    Reddy, M.S.2    Chaluvadi, M.R.3    Krishna, D.R.4
  • 6
    • 0029610477 scopus 로고
    • Review of the biology of quercetin and related bio-flavonoids
    • Formica, J.V.; Regelson, W. Review of the biology of quercetin and related bio-flavonoids. Food Chem. Toxicol., 1995, 33, 1061-1080.
    • (1995) Food Chem. Toxicol , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 9
    • 10944235044 scopus 로고    scopus 로고
    • Anti-inflammatory plant flavonoids and cellular action mechanisms
    • Kim, H.P.; Son, K.H.; Chang, H.W.; Kang, S.S. Anti-inflammatory plant flavonoids and cellular action mechanisms. J. Pharmacol. Sci., 2004, 96, 229-245.
    • (2004) J. Pharmacol. Sci , vol.96 , pp. 229-245
    • Kim, H.P.1    Son, K.H.2    Chang, H.W.3    Kang, S.S.4
  • 10
    • 0023629450 scopus 로고
    • Effect of chronic treatment with a purified flavonoid fraction on inflammatory granuloma in the rat. Study of prostaglandin E2 and F2 and thromboxane B2 release and histological changes
    • Damon, M.; Flandre, O.; Fichel, F. Effect of chronic treatment with a purified flavonoid fraction on inflammatory granuloma in the rat. Study of prostaglandin E2 and F2 and thromboxane B2 release and histological changes. Arzneim-Forsch/Drug Res., 1987, 37, 1149-1153.
    • (1987) Arzneim-Forsch/Drug Res , vol.37 , pp. 1149-1153
    • Damon, M.1    Flandre, O.2    Fichel, F.3
  • 11
    • 2442586419 scopus 로고    scopus 로고
    • Inhibition of phospholipase C-1 by the prenylated flavonoids from Sophora flavescens
    • Lee, H.S.; Ko, H.R.; Ryu, S.Y.; Oh, W.K.; Kim, B.Y.; Ahn, S.C.; Mheen, T.I.; Ahn, J. S. Inhibition of phospholipase C-1 by the prenylated flavonoids from Sophora flavescens. Planta Med., 1997, 63, 266-268.
    • (1997) Planta Med , vol.63 , pp. 266-268
    • Lee, H.S.1    Ko, H.R.2    Ryu, S.Y.3    Oh, W.K.4    Kim, B.Y.5    Ahn, S.C.6    Mheen, T.I.7    Ahn, J.S.8
  • 12
    • 0032997966 scopus 로고    scopus 로고
    • Inhibition of rat adjuvant-induced arthritis by ginkgetin and biflavone
    • Kim, H.K.; Son, K.H.; Chang, H.W.; Kang, S.S.; Kim, H.P. Inhibition of rat adjuvant-induced arthritis by ginkgetin and biflavone. Planta Med., 1999, 65, 465-467.
    • (1999) Planta Med , vol.65 , pp. 465-467
    • Kim, H.K.1    Son, K.H.2    Chang, H.W.3    Kang, S.S.4    Kim, H.P.5
  • 13
    • 0030888257 scopus 로고    scopus 로고
    • Gil, B.; Jesús Sanz, M.; Terencio, M.C.; Gunasegaran, R.; Payá, M.; Alcarazet M. J. Morelloflavone, a novel bioflavonoid inhibitor of human secretary phospholipase A2 with anti-inflammatory activity. Biochem. Pharmacol., 1997, 53, 733-740.
    • Gil, B.; Jesús Sanz, M.; Terencio, M.C.; Gunasegaran, R.; Payá, M.; Alcarazet M. J. Morelloflavone, a novel bioflavonoid inhibitor of human secretary phospholipase A2 with anti-inflammatory activity. Biochem. Pharmacol., 1997, 53, 733-740.
  • 14
    • 0034062416 scopus 로고    scopus 로고
    • Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells
    • Kimata, M.; Shichijo, M.; Miura, T. Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells. Clin. Exp. Allergy, 2000, 30, 501-508.
    • (2000) Clin. Exp. Allergy , vol.30 , pp. 501-508
    • Kimata, M.1    Shichijo, M.2    Miura, T.3
  • 15
    • 20344407841 scopus 로고    scopus 로고
    • Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications
    • Lastra, C.A.; Villegas, I. Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications. Mol. Nutr. Food Res., 2000, 49(5), 405-430.
    • (2000) Mol. Nutr. Food Res , vol.49 , Issue.5 , pp. 405-430
    • Lastra, C.A.1    Villegas, I.2
  • 16
    • 50449111165 scopus 로고    scopus 로고
    • Update on uses and properties of citrus flavonoids: New findings in anticancer, cardiovascular, and anti-inflammatory activity
    • Benavente-García, O.; Castillo, J. Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity. J. Agric. Food Chem., 2008, 56, 6185-6205.
    • (2008) J. Agric. Food Chem , vol.56 , pp. 6185-6205
    • Benavente-García, O.1    Castillo, J.2
  • 17
    • 84892138934 scopus 로고
    • The impact of plant flavonoids on mammalian biology: Implications for immunity, inflammation, and cancer
    • Ed. Harborne, J. B: London
    • Middleton, E. Jr.; Kandaswami, C. The impact of plant flavonoids on mammalian biology: Implications for immunity, inflammation, and cancer. In: Advances in Flavonoid Research, Ed. Harborne, J. B: London, 1993, 619-652.
    • (1993) Advances in Flavonoid Research , pp. 619-652
    • Middleton Jr., E.1    Kandaswami, C.2
  • 18
    • 0032410759 scopus 로고    scopus 로고
    • Grape juice but not orange or grapefruit juice inhibits platelet activity in dogs and monkeys
    • Osman, H.E.; Maalej, N.; Shanmuganayagam, D.; Folts, J.D. Grape juice but not orange or grapefruit juice inhibits platelet activity in dogs and monkeys. J. Nutr., 1998, 128, 2307-2312.
    • (1998) J. Nutr , vol.128 , pp. 2307-2312
    • Osman, H.E.1    Maalej, N.2    Shanmuganayagam, D.3    Folts, J.D.4
  • 20
    • 0023635446 scopus 로고
    • Modification of arachidonic metabolism by flavonoids
    • Alcaraz, M.J.; Ferrandiz, M.L. Modification of arachidonic metabolism by flavonoids. J. Ethnopharmacol., 1987, 21, 209-29.
    • (1987) J. Ethnopharmacol , vol.21 , pp. 209-229
    • Alcaraz, M.J.1    Ferrandiz, M.L.2
  • 21
    • 0025941984 scopus 로고
    • Inhibition of platelet aggregation by some flavonoids
    • Tzeng, S.H.; Ko, W.C.; Ko, F.N.; Teng, C.M. Inhibition of platelet aggregation by some flavonoids. Thromb. Res., 1991, 64, 91-100.
    • (1991) Thromb. Res , vol.64 , pp. 91-100
    • Tzeng, S.H.1    Ko, W.C.2    Ko, F.N.3    Teng, C.M.4
  • 22
    • 0021259185 scopus 로고
    • Modification of platelet function and arachidonic acid metabolism by bioflavonoids, Structure-activity relations
    • Landolfi, R.; Mower, R.L.; Steiner, M. Modification of platelet function and arachidonic acid metabolism by bioflavonoids, Structure-activity relations. Biochem. Pharmacol., 1984, 33, 1525-30.
    • (1984) Biochem. Pharmacol , vol.33 , pp. 1525-1530
    • Landolfi, R.1    Mower, R.L.2    Steiner, M.3
  • 23
    • 0021083237 scopus 로고
    • Effects of antioxidants on cyclooxygenase and lipoxygenase activities in intact human platelets: Comparison with indomethacin and ETYA
    • Van Wauwe, J.; Goossens, J. Effects of antioxidants on cyclooxygenase and lipoxygenase activities in intact human platelets: comparison with indomethacin and ETYA. Prostaglandins, 1983, 26, 725-730.
    • (1983) Prostaglandins , vol.26 , pp. 725-730
    • Van Wauwe, J.1    Goossens, J.2
  • 24
    • 0029929692 scopus 로고    scopus 로고
    • Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells
    • Dehmlow, C.; Murawski, N.; de Groot, H. Scavenging of reactive oxygen species and inhibition of arachidonic acid metabolism by silibinin in human cells. Life Sci., 1996, 58, 1591-1600.
    • (1996) Life Sci , vol.58 , pp. 1591-1600
    • Dehmlow, C.1    Murawski, N.2    de Groot, H.3
  • 25
    • 0032805257 scopus 로고    scopus 로고
    • Inhibition of leukocyte eicosanoid generation and radical scavenging activities of gnaphalin, a lipophilic flavonol isolated from Helichrysum picardii
    • De la Puerta, R.; Forder, R.A.; Hoult, J.R. Inhibition of leukocyte eicosanoid generation and radical scavenging activities of gnaphalin, a lipophilic flavonol isolated from Helichrysum picardii. Planta Med., 1999, 65, 507-511.
    • (1999) Planta Med , vol.65 , pp. 507-511
    • De la Puerta, R.1    Forder, R.A.2    Hoult, J.R.3
  • 27
    • 0031962808 scopus 로고    scopus 로고
    • Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea pigs
    • Kim, H.P.; Manj, I.; Iversen, L.; Ziboh, V.A. Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea pigs. Prostaglandins Leukot. Essent. Fatty Acids, 1998, 58, 17-24.
    • (1998) Prostaglandins Leukot. Essent. Fatty Acids , vol.58 , pp. 17-24
    • Kim, H.P.1    Manj, I.2    Iversen, L.3    Ziboh, V.A.4
  • 28
    • 0032831286 scopus 로고    scopus 로고
    • Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages
    • Liang, Y.C.; Huang, Y.T.; Tsai, S.H.; Lin-Shiau, S.Y.; Chen, C.F.; Lin, J.K. Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis, 1999, 20, 1945-1952.
    • (1999) Carcinogenesis , vol.20 , pp. 1945-1952
    • Liang, Y.C.1    Huang, Y.T.2    Tsai, S.H.3    Lin-Shiau, S.Y.4    Chen, C.F.5    Lin, J.K.6
  • 29
    • 0026583736 scopus 로고
    • Effects of flavonoids on immune and inflammatory cell function
    • Middleton, E. Jr.; Kandaswami, C. Effects of flavonoids on immune and inflammatory cell function. Biochem. Pharmacol., 1992, 43, 1167-1179.
    • (1992) Biochem. Pharmacol , vol.43 , pp. 1167-1179
    • Middleton Jr., E.1    Kandaswami, C.2
  • 30
    • 0019841431 scopus 로고
    • Inhibitory effect of some flavonoids and flavonoid mixtures on cyclic AMP phosphodiesterase activity of rat heart
    • Petkov, E.; Nokolov, N.; Uzunov, P. Inhibitory effect of some flavonoids and flavonoid mixtures on cyclic AMP phosphodiesterase activity of rat heart. Planta Med., 1981, 43, 183-186.
    • (1981) Planta Med , vol.43 , pp. 183-186
    • Petkov, E.1    Nokolov, N.2    Uzunov, P.3
  • 31
    • 0025794373 scopus 로고
    • Inhibition of adenosine 38, 58-cyclic monophosphate phosphodiesterase by flavonoids from licorice roots and 4-arylcoumarins
    • Kusano, A.; Nikaido, T.; Kuge, T.; Ohmoto, T.; Delle Monache, G.; Botta, B.; Botta, M.; Saitoh, T. Inhibition of adenosine 38, 58-cyclic monophosphate phosphodiesterase by flavonoids from licorice roots and 4-arylcoumarins. Chem. Pharm. Bull., 1991, 39, 930-933.
    • (1991) Chem. Pharm. Bull , vol.39 , pp. 930-933
    • Kusano, A.1    Nikaido, T.2    Kuge, T.3    Ohmoto, T.4    Delle Monache, G.5    Botta, B.6    Botta, M.7    Saitoh, T.8
  • 32
    • 0031730652 scopus 로고    scopus 로고
    • Inhibition of cAMP phosphodiesterase by biflavones of Ginkgo biloba in rat adipose tissue
    • Saponara, R.; Bosisio, E. Inhibition of cAMP phosphodiesterase by biflavones of Ginkgo biloba in rat adipose tissue. J. Nat. Prod., 1998, 61, 1386-1387.
    • (1998) J. Nat. Prod , vol.61 , pp. 1386-1387
    • Saponara, R.1    Bosisio, E.2
  • 33
    • 0032941919 scopus 로고    scopus 로고
    • Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-a expression by human monocytes
    • Manthey, J.A.; Grohmann, K.; Montanari, A.; Ash, K.; Manthey, C.L. Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-a expression by human monocytes. J. Nat. Prod., 1999, 62, 441-444.
    • (1999) J. Nat. Prod , vol.62 , pp. 441-444
    • Manthey, J.A.1    Grohmann, K.2    Montanari, A.3    Ash, K.4    Manthey, C.L.5
  • 34
    • 0033017616 scopus 로고    scopus 로고
    • Suppression of lipopolysaccharide-induced tumor necrosis factorrelease and liver injury in mice by naringin
    • Kawaguchi, K.; Kikuchi, S.; Hasegawa, H.; Maruyama, H.; Morita H.; Kumazawa, Y. Suppression of lipopolysaccharide-induced tumor necrosis factorrelease and liver injury in mice by naringin. J. Pharmacol., 1999, 368, 245-250.
    • (1999) J. Pharmacol , vol.368 , pp. 245-250
    • Kawaguchi, K.1    Kikuchi, S.2    Hasegawa, H.3    Maruyama, H.4    Morita, H.5    Kumazawa, Y.6
  • 36
    • 0030479984 scopus 로고    scopus 로고
    • Selective inhibition of tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression by a novel flavonoid. Lack of effect on transcription factor NF-kB
    • Wolle, J.; Hill, R.R.; Ferguson, E.; Devall, L.J.; Trivedi, B.K.; Newton, R.S.; Saxena, U. Selective inhibition of tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression by a novel flavonoid. Lack of effect on transcription factor NF-kB. Arterioscler. Thromb Vasc. Biol., 1996, 16, 1501-1508.
    • (1996) Arterioscler. Thromb Vasc. Biol , vol.16 , pp. 1501-1508
    • Wolle, J.1    Hill, R.R.2    Ferguson, E.3    Devall, L.J.4    Trivedi, B.K.5    Newton, R.S.6    Saxena, U.7
  • 37
    • 0024550507 scopus 로고
    • Protein kinase C inhibition by plant flavonoids. Kinetic mechanisms and structure-activity relationships
    • Ferriola, P.C.; Cody, V.; Middleton, E. Jr. Protein kinase C inhibition by plant flavonoids. Kinetic mechanisms and structure-activity relationships. Biochem. Pharmacol., 1989, 38, 1617-1624.
    • (1989) Biochem. Pharmacol , vol.38 , pp. 1617-1624
    • Ferriola, P.C.1    Cody, V.2    Middleton Jr., E.3
  • 39
    • 0029912466 scopus 로고    scopus 로고
    • Inhibition of protein kinase C and protooncogene expression in NIH 3T3 cells by apigenin
    • Huang, Y. T.; Kuo, M. L.; Liu, J.Y.; Huang, S.Y.; Lin, J.K. Inhibition of protein kinase C and protooncogene expression in NIH 3T3 cells by apigenin. Eur. J. Cancer, 1996, 32, 146-151.
    • (1996) Eur. J. Cancer , vol.32 , pp. 146-151
    • Huang, Y.T.1    Kuo, M.L.2    Liu, J.Y.3    Huang, S.Y.4    Lin, J.K.5
  • 40
    • 0031394645 scopus 로고    scopus 로고
    • Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin
    • Lin, J.K.; Chen, Y.C.; Huang, Y.T.; Lin-Shiau, S.Y. Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. J. Cell Biochem. Suppl., 1997, 29, 39-48.
    • (1997) J. Cell Biochem. Suppl , vol.29 , pp. 39-48
    • Lin, J.K.1    Chen, Y.C.2    Huang, Y.T.3    Lin-Shiau, S.Y.4
  • 42
    • 0032756794 scopus 로고    scopus 로고
    • Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis associated properties in A431 cells over expressing epidermal growth factor receptor
    • Huang, Y.T.; Hwang, J.J.; Lee, P.P.; Ke, F.C.; Huang, J.H.; Huang, C.J.; Kandaswami, C.; Middleton, E.; Lee, M.T. Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis associated properties in A431 cells over expressing epidermal growth factor receptor. Br. J. Pharmacol., 1999, 128, 999-1010.
    • (1999) Br. J. Pharmacol , vol.128 , pp. 999-1010
    • Huang, Y.T.1    Hwang, J.J.2    Lee, P.P.3    Ke, F.C.4    Huang, J.H.5    Huang, C.J.6    Kandaswami, C.7    Middleton, E.8    Lee, M.T.9
  • 43
    • 0032863640 scopus 로고    scopus 로고
    • Quercetin induced apoptosis in colorectal tumor cells: Possible role of EGF receptor signaling
    • Richter, M.; Ebermann, R.; Marian, B. Quercetin induced apoptosis in colorectal tumor cells: Possible role of EGF receptor signaling. Nutr. Cancer, 1999, 34, 88-99.
    • (1999) Nutr. Cancer , vol.34 , pp. 88-99
    • Richter, M.1    Ebermann, R.2    Marian, B.3
  • 44
    • 0032080609 scopus 로고    scopus 로고
    • A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells
    • Zi, X.; Grasso, A.W.; Kung, H.J.; Agarwal, R. A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells. Cancer Res., 1998, 58, 1920-1929.
    • (1998) Cancer Res , vol.58 , pp. 1920-1929
    • Zi, X.1    Grasso, A.W.2    Kung, H.J.3    Agarwal, R.4
  • 45
    • 0030842112 scopus 로고    scopus 로고
    • Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition
    • Agullo, G.; Gamet, P.L.; Manenti, S.; Viala, C.; Remesy, C.; Chap, H.; Payrastre, B. Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition. Biochem. Pharmacol., 1997, 53, 1649-1657.
    • (1997) Biochem. Pharmacol , vol.53 , pp. 1649-1657
    • Agullo, G.1    Gamet, P.L.2    Manenti, S.3    Viala, C.4    Remesy, C.5    Chap, H.6    Payrastre, B.7
  • 46
    • 0032831286 scopus 로고    scopus 로고
    • Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages
    • Liang, Y.C.; Huang, Y.T.; Tsai, S.H.; Lin-Shiau, S.Y.; Chen C.F.; Lin. J.K.; Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages. Carcinogenesis, 1999, 20, 1945-1952.
    • (1999) Carcinogenesis , vol.20 , pp. 1945-1952
    • Liang, Y.C.1    Huang, Y.T.2    Tsai, S.H.3    Lin-Shiau, S.Y.4    Chen, C.F.5    Lin, J.K.6
  • 47
    • 0033567458 scopus 로고    scopus 로고
    • Suppression of TNF-α -mediated NF-kB activity by myricetin and other flavonoids through downregulating the activity of IKK and ECV304 cell
    • Tsai, S.H.; Liang, Y.C.; Lin-Shiau, S.Y.; Lin, J.K. Suppression of TNF-α -mediated NF-kB activity by myricetin and other flavonoids through downregulating the activity of IKK and ECV304 cell. J. Cell Biochem., 1999, 74, 606-615.
    • (1999) J. Cell Biochem , vol.74 , pp. 606-615
    • Tsai, S.H.1    Liang, Y.C.2    Lin-Shiau, S.Y.3    Lin, J.K.4
  • 48
    • 0032715311 scopus 로고    scopus 로고
    • Silymarin suppresses TNF-α -induced activation of NF-kB, c-Jun N-terminal kinase, and apoptosis
    • Manna, S.K.; Mukhopadhyay, A.; Van, N.T.; Agarwal, B.B. Silymarin suppresses TNF-α -induced activation of NF-kB, c-Jun N-terminal kinase, and apoptosis. J. Immunol., 1999, 163, 6800-6809.
    • (1999) J. Immunol , vol.163 , pp. 6800-6809
    • Manna, S.K.1    Mukhopadhyay, A.2    Van, N.T.3    Agarwal, B.B.4
  • 49
    • 34347381789 scopus 로고    scopus 로고
    • Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection
    • Tipoe, G.L.; Leung, T.M.; Hung, M.W.; Fung, M.L. Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection. Cardiovasc. Hematol. Disord. Drug Targets, 2007, 7, 135-144.
    • (2007) Cardiovasc. Hematol. Disord. Drug Targets , vol.7 , pp. 135-144
    • Tipoe, G.L.1    Leung, T.M.2    Hung, M.W.3    Fung, M.L.4
  • 50
    • 33646379112 scopus 로고    scopus 로고
    • Anti-inflammatory and antiarthritic effects of Yucca schidigera: A review
    • Cheeke, P.; Piacente, S.; Oleszek, W. Anti-inflammatory and antiarthritic effects of Yucca schidigera: A review. J. Inflamm., 2006, 3, 6.
    • (2006) J. Inflamm , vol.3 , pp. 6
    • Cheeke, P.1    Piacente, S.2    Oleszek, W.3
  • 51
    • 48749084269 scopus 로고    scopus 로고
    • Anti-inflammatory activities of flavonoids and a triterpene caffeate isolated from Bauhinia variegate
    • Rao, Y. K.; Fang, S. H.; Tzeng, Y.M. Anti-inflammatory activities of flavonoids and a triterpene caffeate isolated from Bauhinia variegate. Phytother. Res., 2008, 22, 957-962.
    • (2008) Phytother. Res , vol.22 , pp. 957-962
    • Rao, Y.K.1    Fang, S.H.2    Tzeng, Y.M.3


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