Early life manganese exposure upregulates tumor-associated genes in the hypothalamus of female rats: Relationship to manganese-induced precocious puberty

Toxicological Sciences

Volumn 136, Issue 2, 2013, Pages 373-381

  Srivastava, Vinod K ^a   Hiney, Jill K ^a   Dees, William L ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

KiSS 1; Mammalian target of rapamycin; Manganese; Puberty; Ras homologue enriched in brain

Indexed keywords

CARBON DIOXIDE; ESTRADIOL; GONADORELIN; MANGANESE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; BLOOD ANALYSIS; BRAIN TISSUE; CONTROLLED STUDY; ENTERIC FEEDING; ENVIRONMENTAL EXPOSURE; FEMALE; GENE; GENE EXPRESSION; HYPOTHALAMUS; NONHUMAN; PERINATAL PERIOD; PRECOCIOUS PUBERTY; PREOPTIC AREA; PUBERTY; RAT; TUMOR ASSOCIATED GENE; UPREGULATION;

KISS-1; MAMMALIAN TARGET OF RAPAMYCIN.; MANGANESE; PUBERTY; RAS HOMOLOGUE ENRICHED IN BRAIN;

ANIMALS; FEMALE; HYPOTHALAMUS; MANGANESE; NEOPLASM PROTEINS; NEOPLASMS, EXPERIMENTAL; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEXUAL MATURATION; UP-REGULATION;

EID: 84890391714     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft195     Document Type: Article

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