Activation of the cAMP/PKA pathway induces UT-A1 urea transporter monoubiquitination and targets it for lysosomal degradation

American Journal of Physiology - Renal Physiology

Volumn 305, Issue 12, 2013, Pages

  Su, Hua ^a,b   Chen, Minguang ^a   Sands, Jeff M ^a   Chen, Guangping ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Endocy tosis; Membrane protein; Phosphorylation; Trafficking; Vasopressin

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; PROTEIN; UNCLASSIFIED DRUG; UREA TRANSPORTER A1 PROTEIN; VASOPRESSIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; UBIQUITINATION;

ENDOCYTOSIS; MEMBRANE PROTEIN; PHOSPHORYLATION; TRAFFICKING; VASOPRESSIN;

ANIMALS; BENZOATES; COLFORSIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOGS; ENDOCYTOSIS; ENZYME INHIBITORS; FURANS; HEK293 CELLS; HUMANS; KIDNEY; LYSOSOMES; MADIN DARBY CANINE KIDNEY CELLS; MEMBRANE TRANSPORT PROTEINS; MODELS, ANIMAL; PYRAZOLES; SERINE; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 84890349504     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00393.2013     Document Type: Article

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