Advance in studies on anti-tumor mechanism of matrine

Zhongguo Zhongyao Zazhi

Volumn 38, Issue 20, 2013, Pages 3409-3412

  Guo, Lin Feng ^a   Tong, Shan Shan ^a   Yu, Jiang Nan ^a   Xu, Xi Ming ^a  

^a JIANGSU UNIVERSITY   (China)

Author keywords

Anti tumor; Matrine; Mechanism

Indexed keywords

ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRINE;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; AUTOPHAGY; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE ARREST; CELL MIGRATION; MEDICAL EDUCATION; MEDICINAL PLANT; REVIEW; SOPHORA ALOPECUROIDES; SOPHORA FLAVESCENS; SOPHORA SUBPROSTRATA;

EID: 84890339700     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20132001     Document Type: Review

References (29)

1. Fu Q, Fang Q, Feng B L, et al. Matrine-imprinted monolithic stationary phase for extraction and purification of matrine from Sophorae flavescentis Ait [J]. J Chromatogr B, 2011, 879(13): 894.
2. Guo Z F, Zhang L X, Song C Y, et al. Molecularly imprinted solid-phase extraction of matrine from radix Sophorae tonkinensis [J]. Analyst, 2011, 136(4): 3016.
3. Küçükb N, Özkan S, Adigüzel N. Characterisation and antimicrobial activity of Sophora alopecuroides L. var. alopecuroides alkaloid extracts [J]. Turk J Biol, 2011, 35: 379.
4. Zhang B, Liu Z Y, Li Y Y, et al. Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice [J]. Eur J Pharmacol, 2011, 44(5): 573.
5. Zhao J, Wan X Y, Luo M, et al. Antifibrotic effects of glycyrrhizin and matrine in vitro and in vivo [J]. Biomed Prevent Nutr, 2012, 2(2): 132.
6. + currents (Ik) in PC12 cells [J]. Neurochem Res, 2012, 37(10): 2143.
7. Li X L, Chu W M, Liu J L, et al. Antiarrhythmic properties of long-term treatment with matrine in arrhythmic rat induced by coronary ligation [J]. Biol Pharm Bull, 2009, 32 (9): 1521.
8. Dai Z J, Gao J, Ji Z Z, et al. Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3 [J]. J Ethnopharmacol, 2009, 12(3): 91.
9. Zhang P, Wang Z M, Chong T, et al. Matrine inhibits proliferation and induces apoptosis of the androgen independent prostate cancer cell line PC-3 [J]. Mol Med Rep, 2011, 5(3): 783.
10. Han Y X, Zhang S H, Wu J B, et al. Matrine induces apoptosis of human multiple myeloma cells via activation of the mitochondrial pathway [J]. Leuk Lymphoma, 2010, 51(7): 1337.
11. Zhang J Q, Li Y M, Liu T, et al. Antitumor effect of matrine in human hepatoma G2 cells by inducing apoptosis and autophagy [J]. World J Gastroenterol, 2010, 16(34): 4281.
12. Zhang Z P, Wang Z F, Wu W G, et al. Effects of matrine on proliferation and apoptosis in allbladder carcinoma cells (GBC-SD) [J]. Phytother Res, 2012, 26(6): 932.
13. Zhao B W, Li B, Bai S W, et al. Effects of matrine on proliferation and apoptosis of cultured retinoblastoma cells [J]. Graefes Arch Clin Exp Ophthalmol, 2012, 250(6): 897.
14. Zhu P, Chen J M, Chen S Z, et al. Matrine inhibits vascular smooth muscle cell proliferation by modulating the expression of cell cycle regulatory genes [J]. Acta Pharm Sin, 2010, 31 (10): 1329.
15. Gozuacik D, Kimchi A. Autophagy and cell death [J]. Curr Top Dev Biol, 2007, 78: 217.
16. Zhang S J, Qi J P, Sun L B, et al. Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells [J]. Mol Biol Rep, 2009, 36(4): 791.
17. Li Y, Zhang J, Ma H, et al. Protective role of autophagy in matrine induced gastric cancer cell death [J]. Int J Oncol, 2013, 42(4): 1417.
18. Zhang Y, Zhang H, Yu P F, et al. Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration [J]. Cytotechnology, 2009, 59(3): 191.
19. Liu X Y, Fang H, Yang Z G, et al. Matrine inhibits invasiveness and metastasis of humanmalignant melanoma cell line A375 in vitro [J]. Int J Dermatol, 2008, 47(5): 448.
20. Yu H B, Zhang X B, Li D Y, et al. Matrine inhibits matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells [J]. J Asian Nat Prod Res, 2011, 13(3): 242.
21. Zhang L, Wang T, Wen X, et al. Effect of matrine on HeLa cell adhesion and migration [J]. Eur J Pharmacol, 2007, 563(1): 69.
22. Sangmin Kim, Jae Hyuck Choi, Hye In Lim, et al. Silibinin prevents TPA-induced MMP-9 expression and VEGF secretion by inactivation of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells [J]. Phytomedicine, 2009, 16(6): 573.
23. Liu B, Peng X C, Zheng X L, et al. MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo [J]. Lung Cancer, 2009, 66(2): 169.
24. Li H, Tan G, Jiang X, et al. Theraprutic effects of matrine on primary and metastatic breast cancer [J]. Am J Chin, 2010, 38(6): 1115.
25. Luo C, Zhong H J, Zhu L M, et al. Inhibition of matrine against gastric cancer cell line MNK45 growth and its anti-tumor mechanism [J]. Mol Biol Rep, 2012, 39(5): 5459.
26. Rebecca G, Matthew S, Sankar G. NF-κB, inflammation, and metabolic disease [J]. Cell Metabolism, 2011, 13(1): 11.
27. Klein U, Ghosh S. The Two Faces of NF-κB signaling in cancer evelopment and therapy [J]. Cancer Cell, 2011, 20(5): 556.
28. Hu M J, Zeng H, Wu Y L, et al. Synergistic effects of matrine and 5-fluorouracil on tumor growth of the implanted gastric cancer in nude mice [J]. Chin J Dig Dis, 2005, 6(2): 68.
29. Yu P F, Liu Q, Liu K, et al. Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-κB signaling [J]. Cytotechnology, 2009, 59(3): 219.