Research advances on chemical constituents of Solanum melongena and their pharmacological activities

Chinese Traditional and Herbal Drugs

Volumn 44, Issue 18, 2013, Pages 2615-2622

  Sun, Jing ^a   Gu, Yu Fan ^a   Li, Man Man ^a   Su, Xiao Qin ^a   Li, Hui ^a   Li, Jun ^a   Tu, Peng Fei ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Alkaloid; Caffeoylquinic acid ester; Flavonoid; Solanum melongena L.; Steroidal glycoside

Indexed keywords

PLANT EXTRACT; SOLANUM MELONGENA EXTRACT; UNCLASSIFIED DRUG;

AUBERGINE; DRUG ACTIVITY; DRUG RESEARCH; REVIEW;

EID: 84890323147     PISSN: 02532670     EISSN: None     Source Type: Journal    
DOI: 10.7501/j.issn.0253-2670.2013.18.025     Document Type: Review

References (61)

1. 1999.
2. Whitaker B D, Stommel J R. Distribution of hydroxycinnamic acid conjugates in fruit of commercial eggplant (Solanum melongena L.) cultivars [J]. J Agric Food Chem, 2003, 51: 3448-3454.
3. Ma C, Dastmalchi K, Whitaker B D, et al. Two new antioxidant malonated caffeoylquinic acid isomers in fruit of wild eggplant relatives [J]. J Agric Food Chem, 2011, 59: 9645-9651.
4. Watanabe S, Sakamura S, Obata Y. The structures of acylated anthocyanins in eggplant and perilla and the position of acylation [J]. Agric Biol Chem, 1966, 30: 420-422.
5. 2001, 39(5): 370-378.
6. Ichiyanagi T, Kashiwada Y, Shida Y, et al. Nasunin from eggplant consists of cis-trans isomers of delphinidin 3-[4-(p-coumaroyl)-L-rhamnosyl (1-6) glucopyranoside]-5-glucopyranoside [J]. J Agric Food Chem, 2005, 53: 9472-9477.
7. Sadilova E, Stintzing F C, Carle R. Anthocyanins, colour and antioxidant properties of eggplant (Solanum melongena L.) and violet pepper (Capsicum annuum L.) peel extracts [J]. Z Naturforsch, 2006, 61: 527-535.
8. Tanchev S S, Ruskov P J, Timberlake C F. Anthocyanins of Bulgarian aubergine (Solanum melongena) [J]. Phytochemistry, 1970, 9: 1681-1682.
9. Azuma K, Ohyama A, Ippoushi K. Structures and antioxidant activity of anthocyanins in many accessions of eggplant and its relatives [J]. J Agric Food Chem, 2008, 56: 10154-10159.
10. Barnabas C G G, Nagarajan S. Chemical and pharmacological studies on the leaves of Solanum melongena [J]. Fitoterapia, 1989, 60(1): 77-78.
11. 2009, 9: 2385-2386.
12. 2010.
13. Shen G H, Kiem P V, Cai X F, et al. Solanoflavone, A new biflavonol glycoside from Solanum melongena: seeking for anti-inflammatory components [J]. Arch Pharm Res, 2005, 28(6): 657-659.
14. 1999, 6(6): 381-382.
15. Yoshihara T, Takamatsu S, Sakamura S. Three new phenolic amides from the roots of eggplant (Solanum melongena L.) [J]. Agric Biol Chem, 1978, 42(3): 623-627.
16. Liu X C, Luo J G, Kong L Y. Phenylethyl cinnamides as potential α-glucosidase inhibitors from the roots of Solanum melongena [J]. Nat Prod Commun, 2011, 6(6): 851-853.
17. El-Khrisy E A M, Abdel-Hafez O M, Mahmood K, et al. Constituents of Solanum melongena var. esculentum fruits [J]. Fitoterapia, 1986, 57(6): 440-441.
18. Ahmed K M. Constituents of the aerial parts and roots of some Solanum melongena varieties [J]. Egypt J Pharm Sci, 1996, 37(1/6): 37-44.
19. Eanes C R, Tek N, Kirsoy O, et al. Development of practical HPLC methods of the separation and determination of eggplant steroidal glycoalkaloids and their aglycones [J]. J Liq Chromatogr Relat Technol, 2008, 31: 984-1000.
20. Chiang H C, Chen Y Y. Xanthine oxidase inhibitors from the roots of eggplant (Solanum melongena L.) [J]. J Enzyme Inhib, 1993, 7(3): 225-235.
21. Shvets S A, Kintya P K. Purification of diosgenin from eggplant root. Russia, SU1736500 A1 [P]. 1992-05-30.
22. Shabana M M, Nour M G. Sapogenins from Agave sisalana Perr. and Solanum melongena L. growing in Egypt [J]. Egypt J Pharm Sci, 1976, 16(3): 359-365.
23. Kintya P K, Shvets S A. Melongoside L and melongoside M, steroidal saponins from Solanum melongena seeds [J]. Phytochemistry, 1985, 24(1): 197-198.
24. Kintya P K, Shvets S A. Melongosides N O and P: steroidal saponins from seeds of Solanum melongena [J]. Phytochemistry, 1985, 24(7): 1567-1569.
25. Yoshihara T, Hagihara Y, Nagaoka T, et al. Fungitoxic compounds from the roots of the eggplant stock [J]. Ann Phytopath Soc Japan, 1988, 54(4): 453-459.
26. MacLeod A J, De Troconis N G. Aroma volatiles of aubergine (Solanum melongena) [J]. Phytochemistry, 1983, 22(9): 2077-2079.
27. 2005(3): 10-11.
28. 2003, 19(4): 26-28.
29. 2005, 16(9): 860-861.
30. 2007, 2(3): 59-60.
31. 2007, 2(4): 49-50.
32. 2005, 16(12): 1254-1255.
33. 2005, 16(11): 1088-1089.
34. Han S W, Tae J, Kim J A, et al. The aqueous extract of Solanum melongena inhibits PAR2 agonist-induced inflammation [J]. Clin Chim Acta, 2003, 328: 39-44.
35. Ashish S, Yadav S. Analgesic activity of root extract of Solanum melongena Linn. root [J]. Int J Res Ayurveda Pharm, 2011, 2(5): 1615-1617.
36. Vohora S B, Kumar I, Khan M S. Effect of alkaloids of Solanum melongena on the central nervous system [J]. J Ethnopharmacol, 1984, 11(3): 331-336.
37. Akanitapichat P, Phraibung K, Nuchklang K, et al. Antioxidant and hepatoprotective activities of five eggplant varieties [J]. Food Chem Toxicol, 2010, 18: 3017-3021.
38. Hanson P M, Yang R Y, Tsou S C S, et al. Diversity in eggplant (Solanum melongena) for superoxide scavenging activity, total phenolics, and ascorbic acid [J]. J Food Compos Anal, 2006, 19(6/7): 594-600.
39. Roberto L S, Marta F, Giuseppe M, et al. Thermal treatment of eggplant (Solanum melongena L.) increases the antioxidant content and the inhibitory effect on human neutrophil burst [J]. J Agric Food Chem, 2010, 58(6): 3371-3379.
40. Sudheesh S, Sandhya C, Koshy A S, et al. Antioxidant activity of flavonoids from Solanum melongena [J]. Phytother Res, 1999, 13: 393-396.
41. Noda Y, Kaneyuki T, Igarashi K, et al. Antioxidant activity of nasunin, an anthocyanin in eggplant [J]. Res Commun Mol Pathol Pharmacol, 1998, 102: 175-187.
42. 2008, 24(2): 62-64.
43. Odetolal A A, Iranloye Y O, Akinloye O. Hypolipidaemic potentials of Solanum melongena and Solanum gilo on hypercholesterolemic rabbits [J]. Pakistan J Nutr, 2004, 3(3): 180-187.
44. Sudheesh S, Presannakumar G, Vijayakumar S, et al. Hypolipidemic effect of flavonoids from Solanum melongena [J]. Plant Food Hum Nutr, 1997, 51: 321-330.
45. Botelho F V, Eneas L R, Cesar G C, et al. Effects of eggplant (Solanum melongena) on the atherogenesis and oxidative stress in LDL receptor knock out mice (LDLR-/-) [J]. Food Chem Toxicol, 2004, 42: 1259-1267.
46. Guimaraes P R, Galvao A M, Batista C M. Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects [J]. Braz J Med Biol Res, 2000, 33(9): 1027-1036.
47. 2007, 2(2): 53-54.
48. Kwon Y I, Apostolidis E, Shetty K. In vitro studies of eggplant (Solanum melongena) phenolics as inhibitors of key enzymes relevant for type 2 diabetes and hypertension [J]. Bioresour Technol, 2008, 99(8): 2981-2988.
49. Ferreira L, Carvalho J C T, Maistro E L. Standardized Solanum melongena extract presents protective effects against chromosomal aberrations induced by doxorubicin in Wistar rat bone marrow cells [J]. Cytologia, 2003, 68(2): 177-181.
50. Nagase H, Sasaki K, Kito H, et al. Inhibitory effect of delphinidin from Solanum melongena on human fibrosarcoma HT-1080 invasiveness in vitro [J]. Planta Med, 1998, 64(3): 216-219.
51. 2000(3): 8-9.
52. Matsubara K, Kaneyuki T, Miyake T, et al. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels [J]. J Agric Food Chem, 2005, 53: 6272-6275.
53. 2001, 12(1): 3-4.
54. Lee Y M, Jeong H J, Na H J, et al. Inhibition of immunologic and nonimmunologic stimulation-mediated anaphylactic reactions by water extract of white eggplant (Solanum melongena) [J]. Pharmacol Res, 2001, 43(4): 405-409.
55. Purushothaman A, Ahmad T, Meenatchi P, et al. Combined effects of Solanum trilobatum and Solanum melongena against β-galactosamine induced hepatic damage in rats with reference to marker enzymes and antioxidants status [J]. Biochem: An Indian J, 2012, 6(2): 49-56.
56. Das J, Lahan J P, Srivastava R B. Solanum melongena, a potential source of antifungal agent [J]. Indian J Microbiol, 2010, 50(1): 62-69.
57. Mans D R A, Toelsie J, Mohan S, et al. Spasmogenic effect of a Solanum melongena leaf extract on guiea pig tracheal chains and its possible mechanism (s) [J]. J Ethnopharmacol, 2004, 95: 329-333.
58. Blankemeyer J T, McWilliams M L, Rayburn J R, et al. Developmental toxicology of solamargine and solasonine glycoalkaloids in frog embryos [J]. Food Chem Toxicol, 1998, 36(5): 383-389.
59. Patil B C, Sharman R P, Salunkhe D K, et al. Evaluation of solanine toxicity [J]. Food Cosmet Toxicol, 1972, 10(3): 395-398.
60. Slanina P. Solanine (glcoalkaloids) in potatos: toxicological evaluation [J]. Food Chem Toxicol, 1990, 28(11): 759-761.
61. 2010.