Antioxidant and hepatoprotective activities of five eggplant varieties

Food and Chemical Toxicology

Volumn 48, Issue 10, 2010, Pages 3017-3021

  Akanitapichat, Pannarat ^a   Phraibung, Kallayanee ^a   Nuchklang, Kwunchai ^a   Prompitakkul, Suparichart ^a  

^a UBON RATCHATHANI UNIVERSITY   (Thailand)

Author keywords

Antioxidant; Eggplant; Hepatoprotective

Indexed keywords

CATECHIN; FLAVONOID; GALLIC ACID; METHANOL; PHENOL; TERT BUTYL HYDROPEROXIDE;

ANTIOXIDANT ACTIVITY; ARTICLE; AUBERGINE; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER PROTECTION; NONHUMAN; VARIETAS;

ANTIOXIDANTS; BENZOTHIAZOLES; BIPHENYL COMPOUNDS; CELL LINE; CELL SURVIVAL; DRUG-INDUCED LIVER INJURY; HUMANS; PHENOLS; PICRATES; PLANT EXTRACTS; PROTECTIVE AGENTS; SOLANUM MELONGENA; SULFONIC ACIDS; TERT-BUTYLHYDROPEROXIDE; THAILAND;

SOLANUM MELONGENA;

EID: 77956344763     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.07.045     Document Type: Article

References (33)

1. Alía M., Ramos S., Mateos R., Granado-Serrano A.B., Bravo L., Goya L. Quercetin protects human hepatoma HepG2 against oxidative stress induced by tert-butyl hydroperoxide. Toxicol. Appl. Pharmacol. 2006, 212:110-118.
2. Apak R., Güçlü K., Demirata B., Özyürek M., Çelik S., Bektaşoĝlu B., Berker K., Özyurt D. Comparative evaluation of various total antioxidant capacity assays applied to phenolic compounds with the CUPRAC assay. Molecules 2007, 12:1496-1547.
3. Bors W., Michel C., Stettmaier K. Structure-activity relationships governing antioxidant capacities of plant polyphenols. Methods Enzymol. 2001, 335:166-180.
4. Brand-Williams W., Cuvelier M.E., Berset C. Use of a free radical method to evaluate antioxidant activity. LWT - Food Sci. Technol. 1995, 28:25-30.
5. Cao G., Sofic E., Prior R.L. Antioxidant capacity of tea and common vegetables. J. Agric. Food Chem. 1996, 44:3426-3431.
6. Dewanto V., Wu X., Adom K.K., Liu R.H. Thermal processing enhances the nutritional value of tomatoes by increasing total antioxidant activity. J. Agric. Food Chem. 2002, 50:3010-3014.
7. Djordjevic V.B. Free radicals in cell biology. Int. Rev. Cytol. 2004, 237:57-89.
8. Han S.W., Tae J., Kim J.A., Kim D.K., Seo G.S., Yun K.J., Choi S.C., Kim T.H., Nah Y.H., Lee Y.M. The aqueous extract of Solanum melongena inhibits PAR2 agonist-induced inflammation. Clin. Chim. Acta 2003, 328:39-44.
9. Hanson P.M., Yang R.-Y., Tsou S.C.S., Ledesma D., Engle L., Lee T.-C. Diversity in eggplant (Solanum melongena) for superoxide scavenging activity, total phenolics, and ascorbic acid. J. Food Compos. Anal. 2006, 19:594-600.
10. Huang H.Y., Chang C.K., Tso T.K., Huang J.J., Chang W.W., Tsai Y.C. Antioxidant activities of various fruits and vegetables produced in Taiwan. Int. J. Food Sci. Nutr. 2004, 55:423-429.
11. Kaneyuki T., Noda Y., Traber M.G., Mori A., Packer L. Superoxide anion and hydroxyl radical scavenging activities of vegetable extracts measured using electron spin resonance. Biochem. Mol. Biol. Int. 1999, 47:979-989.
12. Kinjo J., Hirakawa T., Tsuchihashi R., Nagao T., Okawa M., Nohara T., Okabe H. Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells. Biol. Pharm. Bull. 2003, 26:1357-1360.
13. Knasmüller S., Parzefall W., Sanyal R., Ecker S., Schwab C., Uhl M., Mersch-Sundermann V., Williamson G., Hietsch G., Langer T., Darroudi F., Natarajan A.T. Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens. Mutat. Res. 1998, 402:185-202.
14. Lima C.F., Fernandes-Ferreira M., Pereira-Wilson C. Phenolic compounds protect HepG2 cells from oxidative damage: relevance of glutathione levels. Life Sci. 2006, 79:2056-2068.
15. Lima C.F., Valentao P.C.R., Andrade P.B., Seabra R.M., Fernandes-Ferreira M., Pereira-Wilson C. Water and methanolic extracts of Salvia officinalis protect HepG2 cells from t-BHP induced oxidative damage. Chem. Biol. Interact. 2007, 167:107-115.
16. Liu M., Li X.Q., Weber C., Lee C.Y., Brown J., Liu R.H. Antioxidant and antiproliferative activities of raspberries. J. Agric. Food Chem. 2002, 50:2926-2930.
17. Loguercio C., Federico A. Oxidative stress in viral and alcoholic hepatitis. Free Radical Biol. Med. 2003, 34:1-10.
18. Matsubara K., Kaneyuki T., Miyake T., Mori M. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels. J. Agric. Food Chem. 2005, 53:6272-6275.
19. Morisco F., Vitaglione P., Amoruso D., Russo B., Fogliano V., Caporaso N. Foods and liver health. Mol. Aspects Med. 2008, 29:144-150.
20. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
21. Nagata K., Suzuki H., Sakaguchi S. Common pathogenic mechanism in development progression of liver injury caused by non-alcoholic or alcoholic steatohepatitis. J. Toxicol. Sci. 2007, 32:453-468.
22. Noda Y., Kneyuki T., Igarashi K., Mori A., Packer L. Antioxidant activity of nasunin, an anthocyanin in eggplant peels. Toxicology 2000, 148:119-123.
23. Nothmann J., Rylski I., Spigelman M. Color and variations in color intensity of fruit of eggplant cultivars. Sci. Hortic. 1976, 4:191-197.
24. Re R., Pellegrini N., Proteggente A., Pannala A., Yang M., Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biol. Med. 1999, 26:1231-1237.
25. Rice-Evans C., Miller N., Paganga G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 1997, 2:152-159.
26. Rush G.F., Gorski J.R., Ripple M.G., Sowinski J., Bugelski P., Hewitt W.R. Organic hydroperoxide-induced lipid peroxidation and cell death in isolated hepatocytes. Toxicol. Appl. Pharmacol. 1985, 78:473-483.
27. Stommel J.R., Whitaker B.D. Phenolic acid content and composition of eggplant fruit in a germplasm core subset. J. Am. Soc. Hortic. Sci. 2003, 128:704-710.
28. Sudheesh S., Presannakumar G., Vijayakumar S., Vijayalakshmi N.R. Hypolipidemic effect of flavonoids from Solanum melongena. Plant Foods Hum. Nutr. 1997, 51:321-330.
29. Thabrew M.I., Hughes R.D., McFarlane I.G. Screening of hepatoprotective plant components using a HepG2 cell cytotoxicity assay. J. Pharm. Pharmacol. 1997, 49:1132-1135.
30. Thaipong K., Boonprakob U., Crosby K., Cisneros-Zevallos L., Hawkins Byrne D. Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts. J. Food Compos. Anal. 2006, 19:669-675.
31. Valko M., Rhodes C.J., Moncol J., Izakovic M., Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 2006, 160:1-40.
32. Willcox J.K., Ash S.L., Catignani G.L. Antioxidants and prevention of chronic disease. Crit. Rev. Food. Sci. Nutr. 2004, 44:275-295.
33. Yang J., Meyers K.J., van der Heide J., Liu R.H. Varietal differences in phenolic content and antioxidant and antiproliferative activities of onions. J. Agric. Food Chem. 2004, 52:6787-6793.