-
1
-
-
77956358309
-
Pancreatic cancer. Epidemiology and risk factors
-
Krejs, G. J. (2010) Pancreatic cancer. Epidemiology and risk factors. Dig. Dis. 28, 355-358
-
(2010)
Dig. Dis.
, vol.28
, pp. 355-358
-
-
Krejs, G.J.1
-
2
-
-
33750606190
-
Diagnosing pancreatic cancer. The role of percutaneous biopsy and CT
-
Amin, Z., Theis, B., Russell, R. C., House, C., Novelli, M., and Lees, W. R. (2006) Diagnosing pancreatic cancer. The role of percutaneous biopsy and CT. Clin. Radiol. 61, 996-1002
-
(2006)
Clin. Radiol.
, vol.61
, pp. 996-1002
-
-
Amin, Z.1
Theis, B.2
Russell, R.C.3
House, C.4
Novelli, M.5
Lees, W.R.6
-
3
-
-
77950231730
-
Pancreatic cancer. Survival, errors, and evidence
-
Gudjonsson, B. (2009) Pancreatic cancer. Survival, errors, and evidence. Eur. J. Gastroenterol. Hepatol. 21, 1379-1382
-
(2009)
Eur. J. Gastroenterol. Hepatol.
, vol.21
, pp. 1379-1382
-
-
Gudjonsson, B.1
-
4
-
-
79952284127
-
Hallmarks of cancer. The next generation
-
Hanahan, D., and Weinberg, R. A. (2011) Hallmarks of cancer. The next generation. Cell 144, 646-674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
84856655854
-
Proteomic analysis reveals Warburg effect and anomalous metabolism of glutamine in pancreatic cancer cells
-
Zhou, W., Capello, M., Fredolini, C., Racanicchi, L., Piemonti, L., Liotta, L. A., Novelli, F., and Petricoin, E. F. (2012) Proteomic analysis reveals Warburg effect and anomalous metabolism of glutamine in pancreatic cancer cells. J. Proteome Res. 11, 554-563
-
(2012)
J. Proteome Res.
, vol.11
, pp. 554-563
-
-
Zhou, W.1
Capello, M.2
Fredolini, C.3
Racanicchi, L.4
Piemonti, L.5
Liotta, L.A.6
Novelli, F.7
Petricoin, E.F.8
-
6
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby, R. A., and Gillies, R. J. (2004) Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer 4, 891-899
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
7
-
-
0034333026
-
Pancreatic tumors show high levels of hypoxia
-
Koong, A. C., Mehta, V. K., Le, Q. T., Fisher, G. A., Terris, D. J., Brown, J. M., Bastidas, A. J., and Vierra, M. (2000) Pancreatic tumors show high levels of hypoxia. Int. J. Radiat. Oncol. Biol. Phys. 48, 919-922
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.48
, pp. 919-922
-
-
Koong, A.C.1
Mehta, V.K.2
Le, Q.T.3
Fisher, G.A.4
Terris, D.J.5
Brown, J.M.6
Bastidas, A.J.7
Vierra, M.8
-
8
-
-
44449147036
-
Tumor cell metabolism. Cancer's Achilles' heel
-
Kroemer, G., and Pouyssegur, J. (2008) Tumor cell metabolism. Cancer's Achilles' heel. Cancer Cell 13, 472-482
-
(2008)
Cancer Cell
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
9
-
-
0021750757
-
Contributions of glycolysis and oxidative phosphorylation to adenosine 5′-triphosphate production in AS-30D hepatoma cells
-
Nakashima, R. A., Paggi, M. G., and Pedersen, P. L. (1984) Contributions of glycolysis and oxidative phosphorylation to adenosine 5′-triphosphate production in AS-30D hepatoma cells. Cancer Res. 44, 5702-5706
-
(1984)
Cancer Res.
, vol.44
, pp. 5702-5706
-
-
Nakashima, R.A.1
Paggi, M.G.2
Pedersen, P.L.3
-
10
-
-
0026074512
-
Calcium pump of the plasma membrane
-
Carafoli, E. (1991) Calcium pump of the plasma membrane. Physiol. Rev. 71, 129-153
-
(1991)
Physiol. Rev.
, vol.71
, pp. 129-153
-
-
Carafoli, E.1
-
11
-
-
0023069451
-
Intracellular calcium homeostasis
-
Carafoli, E. (1987) Intracellular calcium homeostasis. Annu. Rev. Biochem. 56, 395-433
-
(1987)
Annu. Rev. Biochem.
, vol.56
, pp. 395-433
-
-
Carafoli, E.1
-
13
-
-
33644872533
-
Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis
-
Criddle, D. N., Murphy, J., Fistetto, G., Barrow, S., Tepikin, A. V., Neoptolemos, J. P., Sutton, R., and Petersen, O. H. (2006) Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis. Gastroenterology 130, 781-793
-
(2006)
Gastroenterology
, vol.130
, pp. 781-793
-
-
Criddle, D.N.1
Murphy, J.2
Fistetto, G.3
Barrow, S.4
Tepikin, A.V.5
Neoptolemos, J.P.6
Sutton, R.7
Petersen, O.H.8
-
14
-
-
34250698918
-
Calcium signalling and pancreatic cell death. Apoptosis or necrosis?
-
Criddle, D. N., Gerasimenko, J. V., Baumgartner, H. K., Jaffar, M., Voronina, S., Sutton, R., Petersen, O. H., and Gerasimenko, O. V. (2007) Calcium signalling and pancreatic cell death. Apoptosis or necrosis? Cell Death Differ. 14, 1285-1294
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1285-1294
-
-
Criddle, D.N.1
Gerasimenko, J.V.2
Baumgartner, H.K.3
Jaffar, M.4
Voronina, S.5
Sutton, R.6
Petersen, O.H.7
Gerasimenko, O.V.8
-
15
-
-
14044251591
-
Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane
-
Campanella, M. E., Chu, H., and Low, P. S. (2005) Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane. Proc. Natl. Acad. Sci. U.S.A. 102, 2402-2407
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2402-2407
-
-
Campanella, M.E.1
Chu, H.2
Low, P.S.3
-
18
-
-
84855858785
-
Insulin protects pancreatic acinar cells from cytosolic calcium overload and inhibition of the plasma membrane calcium pump
-
Mankad, P., James, A., Siriwardena, A. K., Elliott, A. C., and Bruce, J. I. (2012) Insulin protects pancreatic acinar cells from cytosolic calcium overload and inhibition of the plasma membrane calcium pump. J. Biol. Chem. 287, 1823-1836
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 1823-1836
-
-
Mankad, P.1
James, A.2
Siriwardena, A.K.3
Elliott, A.C.4
Bruce, J.I.5
-
20
-
-
0035829074
-
Glucose catabolism in the rabbit VX2 tumor model for liver cancer. Characterization and targeting hexokinase
-
Ko, Y. H., Pedersen, P. L., and Geschwind, J. F. (2001) Glucose catabolism in the rabbit VX2 tumor model for liver cancer. Characterization and targeting hexokinase. Cancer Lett. 173, 83-91
-
(2001)
Cancer Lett.
, vol.173
, pp. 83-91
-
-
Ko, Y.H.1
Pedersen, P.L.2
Geschwind, J.F.3
-
21
-
-
0028109165
-
Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer
-
Berrozpe, G., Schaeffer, J., Peinado, M. A., Real, F. X., and Perucho, M. (1994) Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. Int. J. Cancer 58, 185-191
-
(1994)
Int. J. Cancer
, vol.58
, pp. 185-191
-
-
Berrozpe, G.1
Schaeffer, J.2
Peinado, M.A.3
Real, F.X.4
Perucho, M.5
-
22
-
-
0027733796
-
K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mu-tant- enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization
-
Hruban, R. H., van Mansfeld, A. D., Offerhaus, G. J., van Weering, D. H., Allison, D. C., Goodman, S. N., Kensler, T. W., Bose, K. K., Cameron, J. L., and Bos, J. L. (1993) K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mu-tant- enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. Am. J. Pathol. 143, 545-554
-
(1993)
Am. J. Pathol.
, vol.143
, pp. 545-554
-
-
Hruban, R.H.1
Van Mansfeld, A.D.2
Offerhaus, G.J.3
Van Weering, D.H.4
Allison, D.C.5
Goodman, S.N.6
Kensler, T.W.7
Bose, K.K.8
Cameron, J.L.9
Bos, J.L.10
-
23
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
Hingorani, S. R., Petricoin, E. F., Maitra, A., Rajapakse, V., King, C., Jacobetz, M. A., Ross, S., Conrads, T. P., Veenstra, T. D., Hitt, B. A., Kawaguchi, Y., Johann, D., Liotta, L. A., Crawford, H. C., Putt, M. E., Jacks, T., Wright, C. V., Hruban, R. H., Lowy, A. M., and Tuveson, D. A. (2003) Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 4, 437-450
-
(2003)
Cancer Cell
, vol.4
, pp. 437-450
-
-
Hingorani, S.R.1
Petricoin, E.F.2
Maitra, A.3
Rajapakse, V.4
King, C.5
Jacobetz, M.A.6
Ross, S.7
Conrads, T.P.8
Veenstra, T.D.9
Hitt, B.A.10
Kawaguchi, Y.11
Johann, D.12
Liotta, L.A.13
Crawford, H.C.14
Putt, M.E.15
Jacks, T.16
Wright, C.V.17
Hruban, R.H.18
Lowy, A.M.19
Tuveson, D.A.20
more..
-
24
-
-
77952327640
-
Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes
-
Schmidt, M. M., and Dringen, R. (2009) Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes. Front. Neuroenergetics 1, 1
-
(2009)
Front. Neuroenergetics
, vol.1
, pp. 1
-
-
Schmidt, M.M.1
Dringen, R.2
-
25
-
-
18744390391
-
+-ATP- synthase, suppresses the TNF-induced apoptosis
-
+-ATP-synthase, suppresses the TNF-induced apoptosis. Oncogene 21, 8149-8157
-
(2002)
Oncogene
, vol.21
, pp. 8149-8157
-
-
Shchepina, L.A.1
Pletjushkina, O.Y.2
Avetisyan, A.V.3
Bakeeva, L.E.4
Fetisova, E.K.5
Izyumov, D.S.6
Saprunova, V.B.7
Vyssokikh, M.Y.8
Chernyak, B.V.9
Skulachev, V.P.10
-
31
-
-
78649675903
-
2+-mediated motility of human pancreatic duct cells
-
2+-mediated motility of human pancreatic duct cells. Am. J. Physiol. Cell Physiol. 299, C1493-C1503
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.299
-
-
Dong, H.1
Shim, K.N.2
Li, J.M.3
Estrema, C.4
Ornelas, T.A.5
Nguyen, F.6
Liu, S.7
Ramamoorthy, S.L.8
Ho, S.9
Carethers, J.M.10
Chow, J.Y.11
-
34
-
-
0034737703
-
2+ entry pathway by store depletion in cultured hippocampal neurones
-
2+ entry pathway by store depletion in cultured hippocampal neurones. FEBS Lett. 470, 269-272
-
(2000)
FEBS Lett.
, vol.470
, pp. 269-272
-
-
Bouron, A.1
-
36
-
-
0004180703
-
-
2nd Ed., CRC/Taylor& Francis, Boca Raton, FL
-
Putney, J. W. (2006) Calcium Signaling, 2nd Ed., pp. 73-74, CRC/Taylor& Francis, Boca Raton, FL
-
(2006)
Calcium Signaling
, pp. 73-74
-
-
Putney, J.W.1
-
37
-
-
77951695106
-
Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells
-
Voronina, S. G., Barrow, S. L., Simpson, A. W., Gerasimenko, O. V., da Silva Xavier, G., Rutter, G. A., Petersen, O. H., and Tepikin, A. V. (2010) Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells. Gastroenterology 138, 1976-1987
-
(2010)
Gastroenterology
, vol.138
, pp. 1976-1987
-
-
Voronina, S.G.1
Barrow, S.L.2
Simpson, A.W.3
Gerasimenko, O.V.4
Da Silva Xavier, G.5
Rutter, G.A.6
Petersen, O.H.7
Tepikin, A.V.8
-
38
-
-
78651245402
-
Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells
-
Maléth, J., Venglovecz, V., Rázga, Z., Tiszlavicz, L., Rakonczay, Z., Jr., and Hegyi, P. (2011) Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells. Gut 60, 136-138
-
(2011)
Gut
, vol.60
, pp. 136-138
-
-
Maléth, J.1
Venglovecz, V.2
Rázga, Z.3
Tiszlavicz, L.4
Rakonczay Jr., Z.5
Hegyi, P.6
-
39
-
-
84855831798
-
Plasma membrane calcium pump regulation by metabolic stress
-
Bruce, J. (2010) Plasma membrane calcium pump regulation by metabolic stress. World J. Biol. Chem. 1, 221-228
-
(2010)
World J. Biol. Chem.
, vol.1
, pp. 221-228
-
-
Bruce, J.1
-
40
-
-
84863269083
-
Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma
-
Chaika, N. V., Yu, F., Purohit, V., Mehla, K., Lazenby, A. J., DiMaio, D., Anderson, J. M., Yeh, J. J., Johnson, K. R., Hollingsworth, M. A., and Singh, P. K. (2012) Differential expression of metabolic genes in tumor and stromal components of primary and metastatic loci in pancreatic adenocarcinoma. PloS ONE 7, e32996
-
(2012)
PloS ONE
, vol.7
-
-
Chaika, N.V.1
Yu, F.2
Purohit, V.3
Mehla, K.4
Lazenby, A.J.5
DiMaio, D.6
Anderson, J.M.7
Yeh, J.J.8
Johnson, K.R.9
Hollingsworth, M.A.10
Singh, P.K.11
-
41
-
-
4744341871
-
Advanced cancers. Eradication in all cases using 3-bromopyruvate therapy to deplete ATP
-
Ko, Y. H., Smith, B. L., Wang, Y., Pomper, M. G., Rini, D. A., Torbenson, M. S., Hullihen, J., and Pedersen, P. L. (2004) Advanced cancers. Eradication in all cases using 3-bromopyruvate therapy to deplete ATP. Biochem. Biophys. Res. Commun. 324, 269-275
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 269-275
-
-
Ko, Y.H.1
Smith, B.L.2
Wang, Y.3
Pomper, M.G.4
Rini, D.A.5
Torbenson, M.S.6
Hullihen, J.7
Pedersen, P.L.8
-
42
-
-
43649097186
-
3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs
-
Ihrlund, L. S., Hernlund, E., Khan, O., and Shoshan, M. C. (2008) 3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs. Mol. Oncol. 2, 94-101
-
(2008)
Mol. Oncol.
, vol.2
, pp. 94-101
-
-
Ihrlund, L.S.1
Hernlund, E.2
Khan, O.3
Shoshan, M.C.4
-
43
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration.Aswitch in the decision between apoptosis and necrosis
-
Leist, M., Single, B., Castoldi, A. F., Kühnle, S., and Nicotera, P. (1997) Intracellular adenosine triphosphate (ATP) concentration.Aswitch in the decision between apoptosis and necrosis. J. Exp. Med. 185, 1481-1486
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
Castoldi, A.F.3
Kühnle, S.4
Nicotera, P.5
-
44
-
-
60849101819
-
Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells. ROS-mediated cell death by 3-BrPA
-
Kim, J. S., Ahn, K. J., Kim, J. A., Kim, H. M., Lee, J. D., Lee, J. M., Kim, S. J., and Park, J. H. (2008) Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells. ROS-mediated cell death by 3-BrPA. J. Bioenerg. Biomembr. 40, 607-618
-
(2008)
J. Bioenerg. Biomembr.
, vol.40
, pp. 607-618
-
-
Kim, J.S.1
Ahn, K.J.2
Kim, J.A.3
Kim, H.M.4
Lee, J.D.5
Lee, J.M.6
Kim, S.J.7
Park, J.H.8
-
45
-
-
65449119234
-
Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate
-
Chen, Z., Zhang, H., Lu, W., and Huang, P. (2009) Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. Biochim. Biophys. Acta 1787, 553-560
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 553-560
-
-
Chen, Z.1
Zhang, H.2
Lu, W.3
Huang, P.4
-
46
-
-
4244006599
-
Signalling mechanisms and oxidative stress in apoptosis
-
Slater, A. F., Stefan, C., Nobel, I., van den Dobbelsteen, D. J., and Orrenius, S. (1995) Signalling mechanisms and oxidative stress in apoptosis. Toxicol. Lett. 82, 149-153
-
(1995)
Toxicol. Lett.
, vol.82
, pp. 149-153
-
-
Slater, A.F.1
Stefan, C.2
Nobel, I.3
Van Den Dobbelsteen, D.J.4
Orrenius, S.5
-
47
-
-
0037308233
-
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes
-
Kim, J. S., Qian, T., and Lemasters, J. J. (2003) Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology 124, 494-503
-
(2003)
Gastroenterology
, vol.124
, pp. 494-503
-
-
Kim, J.S.1
Qian, T.2
Lemasters, J.J.3
-
48
-
-
0032437405
-
Intracellular ATP, a switch in the decision between apoptosis and necrosis
-
Nicotera, P., Leist, M., and Ferrando-May, E. (1998) Intracellular ATP, a switch in the decision between apoptosis and necrosis. Toxicol. Lett. 102, 139-142
-
(1998)
Toxicol. Lett.
, vol.102
, pp. 139-142
-
-
Nicotera, P.1
Leist, M.2
Ferrando-May, E.3
-
49
-
-
0022137012
-
Energy costs of ion pumping by animal tissues
-
Milligan, L. P., and McBride, B. W. (1985) Energy costs of ion pumping by animal tissues. J. Nutr. 115, 1374-1382
-
(1985)
J. Nutr.
, vol.115
, pp. 1374-1382
-
-
Milligan, L.P.1
McBride, B.W.2
-
50
-
-
0033118649
-
Contributions of mitochondria to animal physiology. From homeostatic sensor to calcium signalling and cell death
-
Duchen, M. R. (1999) Contributions of mitochondria to animal physiology. From homeostatic sensor to calcium signalling and cell death. J. Physiol. 516, 1-17
-
(1999)
J. Physiol.
, vol.516
, pp. 1-17
-
-
Duchen, M.R.1
-
52
-
-
33846649569
-
Phosphorylation of the plasma membrane calcium pump at high ATP concentration. On the mechanism of ATP hydrolysis
-
Echarte, M. M., Rossi, R. C., and Rossi, J. P. (2007) Phosphorylation of the plasma membrane calcium pump at high ATP concentration. On the mechanism of ATP hydrolysis. Biochemistry 46, 1034-1041
-
(2007)
Biochemistry
, vol.46
, pp. 1034-1041
-
-
Echarte, M.M.1
Rossi, R.C.2
Rossi, J.P.3
-
55
-
-
38649097246
-
2+ responses induced by bile
-
2+ responses induced by bile. Pflugers Arch. 455, 1025-1039
-
(2008)
Pflugers Arch.
, vol.455
, pp. 1025-1039
-
-
Barrow, S.L.1
Voronina, S.G.2
Da Silva Xavier, G.3
Chvanov, M.A.4
Longbottom, R.E.5
Gerasimenko, O.V.6
Petersen, O.H.7
Rutter, G.A.8
Tepikin, A.V.9
-
56
-
-
0020478636
-
Effect of red cell membrane binding on the catalytic activity of glyceraldehyde-3-phosphate dehydrogenase
-
Tsai, I. H., Murthy, S. N., and Steck, T. L. (1982) Effect of red cell membrane binding on the catalytic activity of glyceraldehyde-3-phosphate dehydrogenase. J. Biol. Chem. 257, 1438-1442
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 1438-1442
-
-
Tsai, I.H.1
Murthy, S.N.2
Steck, T.L.3
|