Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII

Basic Research in Cardiology

Volumn 108, Issue 6, 2013, Pages

  Sag, Can M ^a,b   Wolff, Hendrik A ^a   Neumann, Kay ^a   Opiela, Marie Kristin ^a   Zhang, Juqian ^b   Steuer, Felicia ^a   Sowa, Thomas ^a   Gupta, Shamindra ^a   Schirmer, Markus ^a   Hünlich, Mark ^a   Rave Fränk, Margret ^a   Hess, Clemens F ^a   Anderson, Mark E ^c   Shah, Ajay M ^b   Christiansen, Hans ^a,d   Maier, Lars S ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF IOWA   (United States)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Calcium; CaMKII; Excitation contraction coupling; Free radicals; Irradiation

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; PHOSPHOLAMBAN; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM HANDLING; CALCIUM TRANSPORT; CONTROLLED STUDY; HEART DISEASE; HEART LEFT VENTRICLE CONTRACTILITY; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; IONIZING RADIATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SARCOPLASMIC RETICULUM;

ANIMALS; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; ECHOCARDIOGRAPHY; ELECTRON SPIN RESONANCE SPECTROSCOPY; IMMUNOBLOTTING; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MYOCYTES, CARDIAC; RADIATION, IONIZING; REACTIVE OXYGEN SPECIES;

EID: 84890308682     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-013-0385-6     Document Type: Article

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