A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 50, 2013, Pages

  Windheim, Mark ^a,b   Southcombe, Jennifer H ^a,c   Kremmer, Elisabeth ^d   Chaplin, Lucy ^a   Urlaub, Doris ^e   Falk, Christine S ^b   Claus, Maren ^e   Mihm, Janine ^f   Braithwaite, Myles ^a   Dennehy, Kevin ^g   Renz, Harald ^h   Sester, Martina ^f   Watzl, Carsten ^e   Burgert, Hans Gerhard ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^f SAARLAND UNIVERSITY   (Germany)

^g UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^h PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Ad19a Ad64; E3 protein shedding; Epidemic keratoconjunctivitis; Subversion of leukocytes

Indexed keywords

BLOCKING ANTIBODY; CD45 ANTIGEN; CELL SURFACE PROTEIN; RECOMBINANT PROTEIN; SEC49K PROTEIN; SEC49K RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; INTRACELLULAR SIGNALING; LEUKOCYTE; LEUKOCYTE ACTIVATION; LEUKOCYTE FUNCTION; LYMPHOID CELL LINE; MEMBRANE BINDING; MOLECULAR WEIGHT; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; SPECIES COMPOSITION; T LYMPHOCYTE; TARGET CELL;

EID: 84890282771     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1312420110     Document Type: Article

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