[Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes

Journal of Biological Chemistry

Volumn 288, Issue 49, 2013, Pages 35358-35371

  Wang, Yuhong ^a   Zankov, Dimitar P ^a   Jiang, Min ^a   Zhang, Mei ^a   Henderson, Scott C ^a   Tseng, Gea Ny ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIAC MYOCYTES; COLOCALIZATION; DELAYED RECTIFIER; INTRACELLULAR COMPARTMENTS; PROTEIN TRANSLOCATION; STRESS-INDUCED; VENTRICULAR MYOCYTES; VENTRICULAR REPOLARIZATION;

BIOCHEMISTRY; BIOLOGY;

CELL MEMBRANES;

CALNEXIN; DELAYED RECTIFIER POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KCNQ1; SLOW DELAYED RECTIFIER POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL SURFACE; CELL VACUOLE; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM STRESS; FLUORESCENCE ANALYSIS; HEART MUSCLE CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTRACELLULAR SPACE; MOLECULAR DYNAMICS; MOLECULAR IMAGING; MOLECULAR MODEL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SWINE;

CONFOCAL MICROSCOPY; ENDOPLASMIC RETICULUM (ER); POTASSIUM CHANNELS; STRESS RESPONSE; TRAFFICKING;

ANIMALS; CALCIUM; CALNEXIN; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOSOL; FLUORESCENCE RESONANCE ENERGY TRANSFER; GUINEA PIGS; HEART ATRIA; HEART VENTRICLES; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; MYOCYTES, CARDIAC; OXIDATIVE STRESS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN TRANSPORT; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECOMBINANT FUSION PROTEINS;

EID: 84890276776     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.504746     Document Type: Article

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